| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 8.88M (10.77%) | 2.11M Increased by +23.80% | Dec 31, 25 |
| 2 | Redmile Group, LLC | 7.73M (9.38%) | -361.10K Decreased by -4.67% | Mar 31, 26 |
| 3 | Deep Track Capital, LP | 7.04M (8.54%) | 979.43K Increased by +13.92% | Dec 31, 25 |
| 4 | Vanguard Group Inc | 5.95M (7.22%) | 1.46M Increased by +24.55% | Dec 31, 25 |
| 5 | General Atlantic Llc | 4.90M (5.94%) | 4.90M Increased by +100.00% | Dec 31, 25 |
| 6 | Morgan Stanley - Brokerage Accounts | 4.88M (5.92%) | 2.62M Increased by +53.68% | Dec 31, 25 |
| 7 | Vestal Point Capital LP | 4.69M (5.69%) | 1.22M Increased by +25.91% | Dec 31, 25 |
| 8 | Baker Bros Advisors LP | 4.66M (5.65%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 9 | FMR Inc | 4.23M (5.14%) | -4.65M Decreased by -109.90% | Dec 31, 25 |
| 10 | State Street Corp | 3.56M (4.32%) | 697.11K Increased by +19.58% | Dec 31, 25 |
| 11 | T. Rowe Price Associates, Inc. | 3.25M (3.94%) | 2.15M Increased by +66.16% | Dec 31, 25 |
| 12 | Point72 Asset Management, L.P. | 3.21M (3.90%) | 340.18K Increased by +10.59% | Dec 31, 25 |
| 13 | Wasatch Advisors Inc. | 2.75M (3.34%) | -814.87K Decreased by -29.63% | Dec 31, 23 |
| 14 | State Street Corporation | 2.73M (3.31%) | 1.81M Increased by +66.24% | Mar 31, 24 |
| 15 | Pictet Asset Manangement SA | 2.73M (3.31%) | -741.46K Decreased by -27.20% | Mar 31, 26 |
| 16 | T. Rowe Price Investment Management,Inc. | 2.47M (3.00%) | 45.67K Increased by +1.85% | Jun 30, 25 |
| 17 | Rubric Capital Management LP | 2.47M (3.00%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 18 | Soleus Capital Management, L.P. | 2.42M (2.94%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 19 | Geode Capital Management, LLC | 2.38M (2.89%) | 502.32K Increased by +21.06% | Dec 31, 25 |
| 20 | Deutsche Bank AG | 2.30M (2.79%) | -191.77K Decreased by -8.36% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.23M (3.92%) | 30.63K Increased by +0.95% | Mar 31, 26 |
| 2 | State Street® SPDR® S&P® Biotech ETF | 3.14M (3.81%) | -22.30K Decreased by -0.71% | Apr 30, 26 |
| 3 | iShares Russell 2000 ETF | 2.38M (2.89%) | 20.07K Increased by +0.84% | Apr 30, 26 |
| 4 | Xtrackers MSCI World Swap ETF 1C | 2.14M (2.60%) | -13.47K Decreased by -0.63% | Dec 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 2.13M (2.58%) | 196.50K Increased by +9.23% | Sep 30, 24 |
| 6 | Pictet-Biotech P USD | 1.78M (2.16%) | 1.78M Increased by +100.00% | Jan 31, 26 |
| 7 | ARK Genomic Revolution ETF | 1.72M (2.09%) | 72.94K Increased by +4.23% | Apr 30, 26 |
| 8 | Fidelity Select Health Care | 1.69M (2.05%) | 90.00K Increased by +5.33% | Jul 31, 25 |
| 9 | ARK Genomic Revolution | 1.63M (1.97%) | 96.44K Increased by +5.93% | Mar 31, 26 |
| 10 | US Small-Cap Growth II Equity Comp | 1.35M (1.64%) | 14.21K Increased by +1.05% | Jun 30, 25 |
| 11 | Eventide Healthcare & Life Sciences I | 1.30M (1.58%) | 1.30M Increased by +100.00% | Dec 31, 25 |
| 12 | Nikko AM ARK Pstv Chg Innovt P JPY Acc | 1.10M (1.33%) | 273.18K Increased by +24.86% | Jun 30, 25 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 1.08M (1.32%) | 39.23K Increased by +3.62% | Mar 31, 26 |
| 14 | Strategic Advisers Fidelity US TtlStk | 1.03M (1.25%) | 20.00K Increased by +1.93% | Jul 31, 25 |
| 15 | Fidelity Advisor Health Care I | 1.00M (1.21%) | 50.00K Increased by +5.00% | Jul 31, 25 |
| 16 | T. Rowe Price New Horizons | 999.63K (1.21%) | -348.37K Decreased by -34.85% | Jul 31, 25 |
| 17 | T. Rowe Price Integrated US SmCapGrEq | 985.71K (1.20%) | 492.85K Increased by +50.00% | Dec 31, 24 |
| 18 | Fidelity Small Cap Index | 981.17K (1.19%) | 11.47K Increased by +1.17% | Feb 28, 26 |
| 19 | Amova ARK Pstv Chg Innovt P JPY Acc | 964.52K (1.17%) | -20.76K Decreased by -2.15% | Mar 31, 26 |
| 20 | Fidelity Small Cap Growth | 948.30K (1.15%) | 0.00 Increased by 0.00% | Feb 28, 26 |