| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 6.90M (12.41%) | 25.59K Increased by +0.37% | Dec 31, 24 |
| 2 | RTW INVESTMENTS, LLC | 4.17M (7.50%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | COMMODORE CAPITAL LP | 3.87M (6.97%) | 524.18K Increased by +13.53% | Dec 31, 24 |
| 4 | Wellington Management Company LLP | 3.50M (6.29%) | 610.14K Increased by +17.44% | Dec 31, 24 |
| 5 | Deerfield Management Co | 2.97M (5.35%) | -435.75K Decreased by -14.66% | Dec 31, 24 |
| 6 | Samlyn Capital, LLC | 2.67M (4.80%) | 57.78K Increased by +2.17% | Dec 31, 24 |
| 7 | venBio Select Advisor LLC | 2.13M (3.82%) | 770.00K Increased by +36.24% | Dec 31, 24 |
| 8 | Franklin Resources Inc | 1.98M (3.57%) | -271.97K Decreased by -13.70% | Dec 31, 24 |
| 9 | BRAIDWELL LP | 1.90M (3.42%) | 358.18K Increased by +18.84% | Sep 30, 23 |
| 10 | Boxer Capital LLC | 1.90M (3.42%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | Boxer Capital Management, LLC | 1.90M (3.42%) | 1.90M Increased by +100.00% | Dec 31, 24 |
| 12 | Holocene Advisors, LP | 1.88M (3.38%) | 242.03K Increased by +12.87% | Dec 31, 24 |
| 13 | Polar Capital Holdings PLC | 1.71M (3.07%) | 439.19K Increased by +25.74% | Dec 31, 24 |
| 14 | Logos Global Management LP | 1.70M (3.06%) | 1.70M Increased by +100.00% | Jun 30, 24 |
| 15 | Paradigm Biocapital Advisors LP | 1.69M (3.04%) | -765.00K Decreased by -45.27% | Dec 31, 24 |
| 16 | Federated Hermes Inc | 1.59M (2.87%) | -413.43K Decreased by -25.95% | Dec 31, 24 |
| 17 | BlackRock Inc | 1.59M (2.85%) | -58.25K Decreased by -3.67% | Dec 31, 24 |
| 18 | Morgan Stanley - Brokerage Accounts | 1.35M (2.43%) | -1.65M Decreased by -122.50% | Sep 30, 24 |
| 19 | Driehaus Capital Management LLC | 1.28M (2.30%) | -78.63K Decreased by -6.14% | Dec 31, 24 |
| 20 | Bvf Inc | 1.28M (2.30%) | 106.80K Increased by +8.35% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 2.38M (4.28%) | 797.38K Increased by +33.53% | Mar 31, 25 |
| 2 | Fidelity Select Health Care | 1.19M (2.14%) | 87.10K Increased by +7.32% | Mar 31, 25 |
| 3 | Polar Capital Healthcare Opports Inc | 948.58K (1.71%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Federated Hermes Kaufmann Small Cap Grow | 941.49K (1.69%) | -168.61K Decreased by -17.91% | Dec 31, 24 |
| 5 | Franklin Biotechnology Discv A(acc)USD | 870.48K (1.57%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Fidelity Select Biotechnology | 856.75K (1.54%) | -18.20K Decreased by -2.12% | Mar 31, 25 |
| 7 | HBM Healthcare Investments AG Ord | 855.20K (1.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | Strategic Advisers Fidelity US TtlStk | 741.45K (1.33%) | 26.91K Increased by +3.63% | Mar 31, 25 |
| 9 | Fidelity® Select Biotechnology | 730.45K (1.31%) | -63.80K Decreased by -8.73% | Nov 30, 23 |
| 10 | Federated Hermes Kaufmann Small Cap A | 707.29K (1.27%) | -234.20K Decreased by -33.11% | Mar 31, 25 |
| 11 | Fidelity Advisor Health Care I | 696.08K (1.25%) | 24.28K Increased by +3.49% | Mar 31, 25 |
| 12 | Federated Hermes Kaufmann Growth | 634.06K (1.14%) | -240.94K Decreased by -38.00% | Dec 31, 24 |
| 13 | Federated Hermes Kaufmann R | 634.06K (1.14%) | -240.94K Decreased by -38.00% | Dec 31, 24 |
| 14 | Lord Abbett Developing Growth A | 554.74K (1.00%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Fidelity Small Cap Growth | 550.82K (0.99%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 16 | Pictet-Biotech P USD | 545.29K (0.98%) | 8.68K Increased by +1.59% | Jan 31, 25 |
| 17 | Franklin US Small Cap Growth Equity | 529.06K (0.95%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Franklin Small Cap Growth Adv | 524.70K (0.94%) | -4.36K Decreased by -0.83% | Mar 31, 25 |
| 19 | Franklin Biotechnology Discovery A | 499.70K (0.90%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | Polar Capital Biotech S Inc | 450.00K (0.81%) | 0.00 Increased by 0.00% | Mar 31, 25 |