| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 7.49M (10.70%) | 523.46K Increased by +6.99% | Jun 30, 25 |
| 2 | Paradigm Biocapital Advisors LP | 4.28M (6.12%) | 912.25K Increased by +21.30% | Jun 30, 25 |
| 3 | RTW INVESTMENTS, LLC | 4.00M (5.71%) | -168.84K Decreased by -4.22% | Jun 30, 25 |
| 4 | Wellington Management Company LLP | 3.73M (5.32%) | -991.45K Decreased by -26.60% | Jun 30, 25 |
| 5 | COMMODORE CAPITAL LP | 3.52M (5.04%) | -947.84K Decreased by -26.89% | Jun 30, 25 |
| 6 | Deerfield Management Co | 3.38M (4.83%) | 210.70K Increased by +6.23% | Jun 30, 25 |
| 7 | venBio Select Advisor LLC | 3.16M (4.51%) | 155.56K Increased by +4.93% | Jun 30, 25 |
| 8 | Samlyn Capital, LLC | 2.38M (3.40%) | -288.75K Decreased by -12.14% | Mar 31, 25 |
| 9 | T. Rowe Price Associates, Inc. | 2.26M (3.23%) | 1.17M Increased by +51.56% | Jun 30, 25 |
| 10 | Holocene Advisors, LP | 2.23M (3.18%) | 351.62K Increased by +15.80% | Jun 30, 25 |
| 11 | Westfield Capital Management Company, L.P. | 2.04M (2.92%) | 541.17K Increased by +26.50% | Jun 30, 25 |
| 12 | BRAIDWELL LP | 1.90M (2.72%) | 358.18K Increased by +18.84% | Sep 30, 23 |
| 13 | Boxer Capital LLC | 1.90M (2.71%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Boxer Capital Management, LLC | 1.90M (2.71%) | 1.90M Increased by +100.00% | Dec 31, 24 |
| 15 | Franklin Resources Inc | 1.84M (2.62%) | -153.62K Decreased by -8.36% | Jun 30, 25 |
| 16 | Logos Global Management LP | 1.70M (2.43%) | 1.70M Increased by +100.00% | Jun 30, 24 |
| 17 | Polar Capital Holdings PLC | 1.61M (2.30%) | -95.81K Decreased by -5.95% | Jun 30, 25 |
| 18 | Woodline Partners LP | 1.54M (2.20%) | 142.73K Increased by +9.25% | Jun 30, 25 |
| 19 | Federated Hermes Inc | 1.53M (2.18%) | 483.96K Increased by +31.66% | Jun 30, 25 |
| 20 | Driehaus Capital Management LLC | 1.37M (1.95%) | 112.09K Increased by +8.20% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 1.69M (2.41%) | -687.83K Decreased by -40.69% | Jun 30, 25 |
| 2 | Fidelity Select Health Care | 1.16M (1.66%) | -40.00K Decreased by -3.45% | Jul 31, 25 |
| 3 | HBM Healthcare Investments AG Ord | 1.00M (1.43%) | 82.59K Increased by +8.26% | Jun 30, 25 |
| 4 | Polar Capital Healthcare Opports Inc | 948.58K (1.35%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 5 | Federated Hermes Kaufmann Small Cap A | 825.00K (1.18%) | 117.71K Increased by +14.27% | Jun 30, 25 |
| 6 | Federated Hermes Kaufmann Small Cap Grow | 825.00K (1.18%) | 117.71K Increased by +14.27% | Jun 30, 25 |
| 7 | Strategic Advisers Fidelity US TtlStk | 745.89K (1.07%) | -52.40K Decreased by -7.03% | Jul 31, 25 |
| 8 | Fidelity® Select Biotechnology | 730.45K (1.04%) | -63.80K Decreased by -8.73% | Nov 30, 23 |
| 9 | Fidelity Select Biotechnology | 708.85K (1.01%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | Federated Hermes Kaufmann Growth | 684.50K (0.98%) | 356.50K Increased by +52.08% | Jun 30, 25 |
| 11 | Federated Hermes Kaufmann R | 684.50K (0.98%) | 356.50K Increased by +52.08% | Jun 30, 25 |
| 12 | Fidelity Advisor Health Care I | 650.00K (0.93%) | -40.00K Decreased by -6.15% | Jul 31, 25 |
| 13 | Franklin Biotechnology Discv A(acc)USD | 638.75K (0.91%) | -144.83K Decreased by -22.67% | Aug 31, 25 |
| 14 | T. Rowe Price New Horizons | 592.27K (0.85%) | 113.69K Increased by +19.20% | Jun 30, 25 |
| 15 | US Small-Cap Growth II Equity Comp | 592.27K (0.85%) | 227.79K Increased by +38.46% | Jun 30, 25 |
| 16 | Pictet-Biotech P USD | 582.63K (0.83%) | 61.26K Increased by +10.52% | May 31, 25 |
| 17 | Franklin Small Cap Growth SMA | 565.58K (0.81%) | 565.54K Increased by +99.99% | Jun 30, 25 |
| 18 | Franklin US Small Cap Growth Equity | 565.58K (0.81%) | 40.88K Increased by +7.23% | Jun 30, 25 |
| 19 | Lord Abbett Developing Growth A | 554.74K (0.79%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | Fidelity Small Cap Growth | 550.82K (0.79%) | 0.00 Increased by 0.00% | Jun 30, 25 |