| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 18.22M (10.94%) | 1.08M Increased by +5.90% | Dec 31, 24 |
| 2 | BlackRock Inc | 16.03M (9.63%) | 1.06M Increased by +6.63% | Dec 31, 24 |
| 3 | Darwin Global Management, Ltd. | 12.96M (7.79%) | 2.46M Increased by +19.01% | Dec 31, 24 |
| 4 | T. Rowe Price Associates, Inc. | 12.70M (7.63%) | 123.43K Increased by +0.97% | Dec 31, 24 |
| 5 | Capital Research & Mgmt Co - Division 3 | 7.12M (4.28%) | 593.21K Increased by +8.34% | Dec 31, 24 |
| 6 | State Street Corp | 6.11M (3.67%) | -72.08K Decreased by -1.18% | Dec 31, 24 |
| 7 | State Street Corporation | 5.91M (3.55%) | -24.81K Decreased by -0.42% | Mar 31, 24 |
| 8 | Baker Bros Advisors LP | 5.01M (3.01%) | 590.95K Increased by +11.80% | Dec 31, 24 |
| 9 | FMR Inc | 4.86M (2.92%) | -2.34M Decreased by -48.09% | Dec 31, 24 |
| 10 | Deep Track Capital, LP | 4.78M (2.87%) | -566.32K Decreased by -11.84% | Mar 31, 24 |
| 11 | Geode Capital Management, LLC | 4.09M (2.46%) | 273.76K Increased by +6.70% | Dec 31, 24 |
| 12 | JPMorgan Chase & Co | 3.29M (1.97%) | -3.33M Decreased by -101.22% | Dec 31, 24 |
| 13 | Artisan Partners Limited Partnership | 3.13M (1.88%) | 242.24K Increased by +7.75% | Dec 31, 24 |
| 14 | RTW INVESTMENTS, LLC | 3.01M (1.81%) | -257.45K Decreased by -8.54% | Dec 31, 24 |
| 15 | Ameriprise Financial Inc | 2.85M (1.71%) | 269.68K Increased by +9.46% | Dec 31, 24 |
| 16 | Fidelity International Ltd | 2.64M (1.58%) | 198.41K Increased by +7.52% | Dec 31, 24 |
| 17 | Suvretta Capital Management, LLC | 2.52M (1.51%) | 498.80K Increased by +19.78% | Jun 30, 24 |
| 18 | William Blair Investment Management, LLC | 2.43M (1.46%) | 12.54K Increased by +0.52% | Dec 31, 24 |
| 19 | AllianceBernstein L.P. | 2.36M (1.42%) | -86.53K Decreased by -3.66% | Dec 31, 24 |
| 20 | Loomis, Sayles & Company LP | 2.33M (1.40%) | -51.53K Decreased by -2.21% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 5.73M (3.44%) | 86.76K Increased by +1.51% | Mar 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 5.46M (3.28%) | 368.94K Increased by +6.76% | Sep 30, 24 |
| 3 | T. Rowe Price New Horizons | 4.61M (2.77%) | -62.37K Decreased by -1.35% | Mar 31, 25 |
| 4 | US Small-Cap Growth II Equity Comp | 4.61M (2.77%) | -138.04K Decreased by -2.99% | Mar 31, 25 |
| 5 | Capital Group Growth Fnd of Amer Comp | 4.54M (2.73%) | 63.68K Increased by +1.40% | Mar 31, 25 |
| 6 | American Funds Growth Fund of Amer A | 4.54M (2.73%) | 63.68K Increased by +1.40% | Mar 31, 25 |
| 7 | Vanguard Small Cap Index | 4.52M (2.71%) | -50.47K Decreased by -1.12% | Mar 31, 25 |
| 8 | iShares Russell 2000 ETF | 4.25M (2.55%) | -34.46K Decreased by -0.81% | Apr 29, 25 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 2.76M (1.65%) | 35.45K Increased by +1.29% | Mar 31, 25 |
| 10 | T. Rowe Price Health Sciences | 2.59M (1.56%) | -21.76K Decreased by -0.84% | Mar 31, 25 |
| 11 | Vanguard Small Cap Growth Index Inv | 2.53M (1.52%) | -33.35K Decreased by -1.32% | Mar 31, 25 |
| 12 | Bellevue Healthcare Ord | 2.41M (1.45%) | -805.59K Decreased by -33.39% | Nov 30, 23 |
| 13 | BioPharma Credit Ord | 2.33M (1.40%) | -2.54M Decreased by -109.23% | Jun 30, 24 |
| 14 | Macquarie US Small Cap Core Equity | 2.21M (1.33%) | -428.38K Decreased by -19.42% | Mar 31, 24 |
| 15 | Delaware US Small Cap Core Equity (SMA) | 2.21M (1.33%) | -428.38K Decreased by -19.42% | Mar 31, 24 |
| 16 | Pictet-Biotech P USD | 2.03M (1.22%) | -9.62K Decreased by -0.47% | Jul 31, 23 |
| 17 | T. Rowe Price Small-Cap Value | 1.96M (1.18%) | -4.10K Decreased by -0.21% | Sep 30, 23 |
| 18 | American Funds SMALLCAP World A | 1.84M (1.11%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | T. Rowe Price Integrated US SmCapGrEq | 1.76M (1.06%) | 757.66K Increased by +43.02% | Dec 31, 24 |
| 20 | SPDR® S&P Biotech ETF | 1.74M (1.05%) | -30.53K Decreased by -1.75% | Apr 30, 25 |