| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Darwin Global Management, Ltd. | 19.34M (10.11%) | 3.95M Increased by +20.40% | Jun 30, 25 |
| 2 | Vanguard Group Inc | 17.64M (9.22%) | -623.63K Decreased by -3.53% | Jun 30, 25 |
| 3 | JPMorgan Chase & Co | 15.64M (8.17%) | 9.28M Increased by +59.36% | Jun 30, 25 |
| 4 | T. Rowe Price Associates, Inc. | 11.23M (5.87%) | -1.69M Decreased by -15.07% | Jun 30, 25 |
| 5 | BlackRock Inc | 11.14M (5.82%) | -4.91M Decreased by -44.03% | Jun 30, 25 |
| 6 | Baker Bros Advisors LP | 7.71M (4.03%) | 2.33M Increased by +30.24% | Jun 30, 25 |
| 7 | Capital Research & Mgmt Co - Division 3 | 7.48M (3.91%) | 280.37K Increased by +3.75% | Jun 30, 25 |
| 8 | State Street Corporation | 5.91M (3.09%) | -24.81K Decreased by -0.42% | Mar 31, 24 |
| 9 | FMR Inc | 5.09M (2.66%) | 1.70M Increased by +33.36% | Jun 30, 25 |
| 10 | Deep Track Capital, LP | 4.78M (2.50%) | -566.32K Decreased by -11.84% | Mar 31, 24 |
| 11 | State Street Corp | 4.28M (2.24%) | -1.47M Decreased by -34.35% | Jun 30, 25 |
| 12 | D. E. Shaw & Co LP | 3.42M (1.79%) | 2.69M Increased by +78.53% | Jun 30, 25 |
| 13 | Geode Capital Management, LLC | 3.34M (1.75%) | -948.03K Decreased by -28.38% | Jun 30, 25 |
| 14 | Artisan Partners Limited Partnership | 3.31M (1.73%) | 97.07K Increased by +2.93% | Jun 30, 25 |
| 15 | RTW INVESTMENTS, LLC | 3.08M (1.61%) | 70.00K Increased by +2.27% | Jun 30, 25 |
| 16 | Ameriprise Financial Inc | 2.96M (1.55%) | 6.35K Increased by +0.21% | Jun 30, 25 |
| 17 | Adage Capital Partners Gp LLC | 2.86M (1.49%) | -587.49K Decreased by -20.55% | Jun 30, 25 |
| 18 | Suvretta Capital Management, LLC | 2.52M (1.32%) | 498.80K Increased by +19.78% | Jun 30, 24 |
| 19 | AllianceBernstein L.P. | 2.42M (1.27%) | 59.95K Increased by +2.47% | Mar 31, 25 |
| 20 | Fidelity International Ltd | 2.39M (1.25%) | -247.96K Decreased by -10.37% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | JPMorgan Large Cap Growth I | 7.10M (3.71%) | 1.57M Increased by +22.06% | Jul 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 5.75M (3.00%) | -128.70K Decreased by -2.24% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 5.46M (2.85%) | 368.94K Increased by +6.76% | Sep 30, 24 |
| 4 | American Funds Growth Fund of Amer A | 4.74M (2.48%) | 196.69K Increased by +4.15% | Jun 30, 25 |
| 5 | Capital Group Growth Fnd of Amer Comp | 4.74M (2.48%) | 196.69K Increased by +4.15% | Jun 30, 25 |
| 6 | Vanguard Small Cap Index | 4.42M (2.31%) | -28.14K Decreased by -0.64% | Jul 31, 25 |
| 7 | iShares Russell 2000 ETF | 4.32M (2.26%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | US Small-Cap Growth II Equity Comp | 3.62M (1.89%) | -996.88K Decreased by -27.57% | Jun 30, 25 |
| 9 | BioPharma Credit Ord | 3.17M (1.66%) | 838.84K Increased by +26.48% | Dec 31, 24 |
| 10 | Vanguard Small Cap Growth Index Inv | 2.49M (1.30%) | -5.21K Decreased by -0.21% | Jul 31, 25 |
| 11 | T. Rowe Price New Horizons | 2.45M (1.28%) | -1.16M Decreased by -47.46% | Jul 31, 25 |
| 12 | T. Rowe Price Health Sciences | 2.43M (1.27%) | 14.46K Increased by +0.60% | Jul 31, 25 |
| 13 | Bellevue Healthcare Ord | 2.41M (1.26%) | -805.59K Decreased by -33.39% | Nov 30, 23 |
| 14 | Delaware US Small Cap Core Equity (SMA) | 2.21M (1.15%) | -428.38K Decreased by -19.42% | Mar 31, 24 |
| 15 | Macquarie US Small Cap Core Equity | 2.21M (1.15%) | -428.38K Decreased by -19.42% | Mar 31, 24 |
| 16 | Pictet-Biotech P USD | 2.03M (1.06%) | -9.62K Decreased by -0.47% | Jul 31, 23 |
| 17 | T. Rowe Price Small-Cap Value | 1.96M (1.03%) | -4.10K Decreased by -0.21% | Sep 30, 23 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 1.96M (1.02%) | -851.00K Decreased by -43.46% | Jul 31, 25 |
| 19 | American Funds SMALLCAP World A | 1.84M (0.96%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | T. Rowe Price Integrated US SmCapGrEq | 1.76M (0.92%) | 757.66K Increased by +43.02% | Dec 31, 24 |