| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 17.14M (10.23%) | 1.13M Increased by +6.59% | Sep 30, 24 |
| 2 | BlackRock Inc | 14.26M (8.51%) | 2.46M Increased by +17.28% | Jun 30, 24 |
| 3 | T. Rowe Price Associates, Inc. | 12.58M (7.50%) | 417.61K Increased by +3.32% | Sep 30, 24 |
| 4 | Darwin Global Management, Ltd. | 10.50M (6.26%) | 6.96M Increased by +66.27% | Sep 30, 24 |
| 5 | FMR Inc | 7.19M (4.29%) | -113.61K Decreased by -1.58% | Sep 30, 24 |
| 6 | Capital Research & Mgmt Co - Division 3 | 6.52M (3.89%) | 653.90K Increased by +10.02% | Sep 30, 24 |
| 7 | State Street Corp | 6.18M (3.69%) | 1.52M Increased by +24.53% | Sep 30, 24 |
| 8 | State Street Corporation | 5.91M (3.52%) | -24.81K Decreased by -0.42% | Mar 31, 24 |
| 9 | Deep Track Capital, LP | 4.78M (2.85%) | -566.32K Decreased by -11.84% | Mar 31, 24 |
| 10 | Baker Bros Advisors LP | 4.42M (2.63%) | 839.88K Increased by +19.02% | Sep 30, 24 |
| 11 | Geode Capital Management, LLC | 3.81M (2.27%) | 172.66K Increased by +4.53% | Sep 30, 24 |
| 12 | JPMorgan Chase & Co | 3.31M (1.97%) | 380.16K Increased by +11.50% | Sep 30, 24 |
| 13 | RTW INVESTMENTS, LLC | 3.27M (1.95%) | -368.10K Decreased by -11.25% | Sep 30, 24 |
| 14 | Artisan Partners Limited Partnership | 2.88M (1.72%) | 394.67K Increased by +13.68% | Sep 30, 24 |
| 15 | Franklin Resources Inc | 2.72M (1.62%) | 3.10K Increased by +0.11% | Sep 30, 24 |
| 16 | Ameriprise Financial Inc | 2.58M (1.54%) | 49.42K Increased by +1.92% | Sep 30, 24 |
| 17 | Suvretta Capital Management, LLC | 2.52M (1.50%) | 498.80K Increased by +19.78% | Jun 30, 24 |
| 18 | AllianceBernstein L.P. | 2.45M (1.46%) | -42.18K Decreased by -1.72% | Sep 30, 24 |
| 19 | Fidelity International Ltd | 2.44M (1.46%) | 921.63K Increased by +37.78% | Sep 30, 24 |
| 20 | William Blair Investment Management, LLC | 2.42M (1.44%) | -1.05M Decreased by -43.32% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BioPharma Credit Ord | 6.93M (4.13%) | 6.93M Increased by +100.00% | Jun 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 5.44M (3.24%) | -22.17K Decreased by -0.41% | Oct 31, 24 |
| 3 | T. Rowe Price New Horizons | 4.77M (2.85%) | -15.03K Decreased by -0.32% | Sep 30, 24 |
| 4 | US Small-Cap Growth II Equity Comp | 4.77M (2.85%) | -16.96K Decreased by -0.36% | Sep 30, 24 |
| 5 | iShares Russell 2000 ETF | 4.37M (2.61%) | -9.14K Decreased by -0.21% | Nov 27, 24 |
| 6 | Vanguard Small Cap Index | 4.31M (2.57%) | 8.45K Increased by +0.20% | Oct 31, 24 |
| 7 | American Funds Growth Fund of Amer A | 3.92M (2.34%) | 547.24K Increased by +13.97% | Sep 30, 24 |
| 8 | Capital Group Growth Fnd of Amer Comp | 3.92M (2.34%) | 547.24K Increased by +13.97% | Sep 30, 24 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 2.56M (1.53%) | -12.08K Decreased by -0.47% | Oct 31, 24 |
| 10 | T. Rowe Price Health Sciences | 2.54M (1.51%) | -24.69K Decreased by -0.97% | Sep 30, 24 |
| 11 | SPDR® S&P Biotech ETF | 2.49M (1.48%) | -75.51K Decreased by -3.04% | Nov 27, 24 |
| 12 | Bellevue Healthcare Ord | 2.41M (1.44%) | -805.59K Decreased by -33.39% | Nov 30, 23 |
| 13 | Vanguard Small Cap Growth Index Inv | 2.37M (1.41%) | -6.09K Decreased by -0.26% | Oct 31, 24 |
| 14 | Delaware US Small Cap Core Equity (SMA) | 2.21M (1.32%) | -428.38K Decreased by -19.42% | Mar 31, 24 |
| 15 | Macquarie US Small Cap Core Equity | 2.21M (1.32%) | -428.38K Decreased by -19.42% | Mar 31, 24 |
| 16 | Pictet-Biotech P USD | 2.03M (1.21%) | -9.62K Decreased by -0.47% | Jul 31, 23 |
| 17 | T. Rowe Price Small-Cap Value | 1.96M (1.17%) | -4.10K Decreased by -0.21% | Sep 30, 23 |
| 18 | American Funds SMALLCAP World A | 1.84M (1.10%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 19 | Fidelity Small Cap Index | 1.59M (0.95%) | -39.98K Decreased by -2.52% | Aug 31, 24 |
| 20 | First Trust NYSE Arca Biotech ETF | 1.45M (0.86%) | 0.00 Increased by 0.00% | Jan 31, 24 |