| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 1.09M (9.09%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | VR Adviser, LLC | 1.05M (8.75%) | 285.80K Increased by +27.18% | Mar 31, 25 |
| 3 | TCG Crossover Management, LLC | 1.01M (8.37%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Adage Capital Partners Gp LLC | 990.00K (8.24%) | 620.05K Increased by +62.63% | Mar 31, 25 |
| 5 | Bvf Inc | 924.64K (7.69%) | -168.15K Decreased by -18.19% | Mar 31, 25 |
| 6 | Bain Capital Life Sciences Investors, LLC | 703.08K (5.85%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Vivo Capital, LLC | 684.28K (5.69%) | 13.68K Increased by +2.00% | Mar 31, 25 |
| 8 | GSA Capital Partners LLP | 540.45K (4.50%) | 403.47K Increased by +74.66% | Dec 31, 23 |
| 9 | Vanguard Group Inc | 509.58K (4.24%) | 292.07K Increased by +57.32% | Mar 31, 25 |
| 10 | Vestal Point Capital LP | 504.54K (4.20%) | 504.54K Increased by +100.00% | Mar 31, 25 |
| 11 | Monashee Investment Management LLC | 369.10K (3.07%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | West Family Investments LLC | 368.91K (3.07%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Susquehanna International Group, LLP | 342.48K (2.85%) | 299.85K Increased by +87.55% | Mar 31, 25 |
| 14 | Connor Clark & Lunn Inv Mgmt Ltd | 316.83K (2.64%) | -12.37K Decreased by -3.90% | Dec 31, 23 |
| 15 | Citadel Advisors Llc | 287.77K (2.39%) | 287.77K Increased by +100.00% | Mar 31, 25 |
| 16 | State Street Corporation | 287.04K (2.39%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 17 | Ikarian Capital, LLC | 248.94K (2.07%) | 195.00K Increased by +78.33% | Mar 31, 25 |
| 18 | XTX Topco Ltd | 161.06K (1.34%) | -41.70K Decreased by -25.89% | Dec 31, 23 |
| 19 | Longwood Capital Partners LLC | 125.71K (1.05%) | 71.23K Increased by +56.67% | Mar 31, 25 |
| 20 | Aberdeen Group PLC | 120.88K (1.01%) | 120.88K Increased by +100.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | MEDICAL BioHealth EUR Acc | 903.90K (7.52%) | -1.06M Decreased by -117.68% | Jan 31, 24 |
| 2 | APO Medical Opportunities R | 777.57K (6.47%) | -484.29K Decreased by -62.28% | Jan 31, 24 |
| 3 | Fidelity® Extended Market Index | 430.40K (3.58%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 417.12K (3.47%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | RIM Global Bioscience EUR | 284.96K (2.37%) | -153.79K Decreased by -53.97% | Dec 31, 23 |
| 6 | BlackRock Extended Mkt Composite | 228.25K (1.90%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | Fidelity® Total Market Index | 123.53K (1.03%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | Vanguard US Total Market Shares ETF | 121.55K (1.01%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | Fidelity® Series Total Market Index | 116.71K (0.97%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 10 | abrdn Healthcare Investors | 84.12K (0.70%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 82.47K (0.69%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Bridgeway Ultra-Small Company | 60.06K (0.50%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 13 | Vanguard Instl Ttl Stck Mkt Idx Tr | 54.78K (0.46%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 14 | Spartan Total Market Index Pool E | 51.58K (0.43%) | 0.00 Increased by 0.00% | Feb 29, 24 |
| 15 | SSgA U.S. Extended Market Index Class I | 43.30K (0.36%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 16 | abrdn Life Sciences Investors | 36.76K (0.31%) | 0.00 Increased by 0.00% | May 31, 25 |
| 17 | NT Ext Eq Mkt Indx Fd DC Lending Tier 5 | 33.54K (0.28%) | 33.40K Increased by +99.59% | Jun 30, 24 |
| 18 | Vifag 2002 SICAV | 26.66K (0.22%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 19 | Fidelity Extended Market Index | 26.38K (0.22%) | -252.00 Decreased by -0.96% | Apr 30, 25 |
| 20 | Sun Life CC&L Group Income & Growth Seg | 17.53K (0.15%) | 17.53K Increased by +100.00% | May 31, 24 |