| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 4.49M (12.87%) | 205.32K Increased by +4.57% | Sep 30, 23 |
| 2 | Vanguard Group Inc | 3.73M (10.69%) | -13.63K Decreased by -0.37% | Sep 30, 23 |
| 3 | BlackRock Inc | 2.93M (8.41%) | 210.95K Increased by +7.19% | Sep 30, 23 |
| 4 | Fairmount Funds Management LLC | 2.36M (6.77%) | 18.84K Increased by +0.8% | Dec 31, 23 |
| 5 | Bvf Inc | 2.13M (6.11%) | 0 Increased by 0% | Sep 30, 23 |
| 6 | FMR Inc | 1.86M (5.33%) | -270.41K Decreased by -14.55% | Sep 30, 23 |
| 7 | Citadel Advisors Llc | 1.3M (3.71%) | 841.31K Increased by +64.93% | Sep 30, 23 |
| 8 | Deep Track Capital, LP | 1.14M (3.27%) | 756.54K Increased by +66.32% | Sep 30, 23 |
| 9 | RA Capital Management, LLC | 1M (2.87%) | 0 Increased by 0% | Sep 30, 23 |
| 10 | State Street Corporation | 867.65K (2.49%) | 42.46K Increased by +4.89% | Sep 30, 23 |
| 11 | Geode Capital Management, LLC | 778.5K (2.23%) | 68.73K Increased by +8.83% | Sep 30, 23 |
| 12 | Alethea Capital Management, LLC | 758.79K (2.18%) | -1.15K Decreased by -0.15% | Sep 30, 23 |
| 13 | Pictet Asset Manangement SA | 646.43K (1.85%) | 646.43K Increased by +100% | Sep 30, 23 |
| 14 | Bellevue Group AG | 635.37K (1.82%) | 3.88K Increased by +0.61% | Dec 31, 23 |
| 15 | Jefferies Financial Group Inc | 553.2K (1.59%) | 553.2K Increased by +100% | Sep 30, 23 |
| 16 | Point72 Asset Management, L.P. | 531.94K (1.53%) | 63.93K Increased by +12.02% | Sep 30, 23 |
| 17 | Partner Fund Management LP | 523.21K (1.5%) | 27.63K Increased by +5.28% | Sep 30, 23 |
| 18 | Millennium Management LLC | 503.04K (1.44%) | -232.06K Decreased by -46.13% | Sep 30, 23 |
| 19 | Perceptive Advisors LLC | 481.65K (1.38%) | 210.16K Increased by +43.63% | Sep 30, 23 |
| 20 | Woodline Partners LP | 452.11K (1.3%) | 12.18K Increased by +2.69% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.19M (3.42%) | 2.31K Increased by +0.19% | Jan 31, 24 |
| 2 | Vanguard Small Cap Index | 966.73K (2.77%) | 2.69K Increased by +0.28% | Jan 31, 24 |
| 3 | iShares Russell 2000 ETF | 879.39K (2.52%) | -16.07K Decreased by -1.83% | Jan 31, 24 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 571.45K (1.64%) | 205 Increased by +0.04% | Jan 31, 24 |
| 5 | Vanguard Small Cap Growth Index Inv | 540.12K (1.55%) | 1.95K Increased by +0.36% | Jan 31, 24 |
| 6 | Eventide Healthcare & Life Sciences I | 346.71K (0.99%) | 346.71K Increased by +100% | Sep 30, 23 |
| 7 | Fidelity Small Cap Index | 346.16K (0.99%) | 6.78K Increased by +1.96% | Nov 30, 23 |
| 8 | Fidelity® Small Cap Index | 339.38K (0.97%) | 9.36K Increased by +2.76% | Oct 31, 23 |
| 9 | Vanguard Small Cap Value Index Inv | 339.12K (0.97%) | -522 Decreased by -0.15% | Nov 30, 23 |
| 10 | iShares Russell 2000 Growth ETF | 309.86K (0.89%) | 363 Increased by +0.12% | Jan 31, 24 |
| 11 | iShares Biotechnology ETF | 287.45K (0.82%) | -263 Decreased by -0.09% | Jan 31, 24 |
| 12 | Pictet-Biotech P USD | 282.08K (0.81%) | -1.34K Decreased by -0.47% | Jul 31, 23 |
| 13 | FIAM Small Cap Core CIT Cl B | 246.04K (0.71%) | 0 Increased by 0% | Nov 30, 23 |
| 14 | FIAM Small Cap Core Composite | 243.34K (0.7%) | 109.24K Increased by +44.89% | Sep 30, 23 |
| 15 | Fidelity Select Biotechnology | 223K (0.64%) | 0 Increased by 0% | Dec 31, 23 |
| 16 | Fidelity® Select Biotechnology | 223K (0.64%) | -33.8K Decreased by -15.16% | Nov 30, 23 |
| 17 | Fidelity Global Innovators Cl F | 214.18K (0.61%) | 389 Increased by +0.18% | Sep 30, 23 |
| 18 | Fidelity Extended Market Index | 214.18K (0.61%) | 4.1K Increased by +1.91% | Dec 31, 23 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 210.65K (0.6%) | 1.6K Increased by +0.76% | Jan 31, 24 |
| 20 | Fidelity® Extended Market Index | 210.08K (0.6%) | 3.67K Increased by +1.75% | Nov 30, 23 |