| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Wellington Management Company LLP | 12.30M (15.88%) | 502.40K Increased by +4.08% | Mar 31, 25 |
| 2 | venBio Select Advisor LLC | 12.22M (15.78%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | EcoR1 Capital, LLC | 11.90M (15.36%) | 4.96K Increased by +0.04% | Mar 31, 25 |
| 4 | Vanguard Group Inc | 10.13M (13.08%) | 84.33K Increased by +0.83% | Mar 31, 25 |
| 5 | Morgan Stanley - Brokerage Accounts | 9.63M (12.43%) | -1.10K Decreased by -0.01% | Mar 31, 25 |
| 6 | JPMorgan Chase & Co | 7.77M (10.03%) | 1.41M Increased by +18.21% | Sep 30, 24 |
| 7 | BlackRock Inc | 6.33M (8.17%) | -148.39K Decreased by -2.34% | Mar 31, 25 |
| 8 | Deep Track Capital, LP | 5.00M (6.45%) | 725.08K Increased by +14.50% | Mar 31, 25 |
| 9 | AQR Capital Management LLC | 4.08M (5.26%) | 2.22M Increased by +54.47% | Mar 31, 25 |
| 10 | State Street Corp | 3.94M (5.09%) | -583.75K Decreased by -14.81% | Mar 31, 25 |
| 11 | Bank of America Corp | 3.13M (4.04%) | 1.45M Increased by +46.34% | Mar 31, 25 |
| 12 | T. Rowe Price Investment Management,Inc. | 2.99M (3.85%) | -1.06M Decreased by -35.61% | Sep 30, 24 |
| 13 | State Street Corporation | 2.91M (3.76%) | -5.89K Decreased by -0.20% | Mar 31, 24 |
| 14 | UBS Group AG | 2.59M (3.34%) | 2.27M Increased by +87.83% | Dec 31, 24 |
| 15 | Siren, L.L.C. | 2.58M (3.33%) | -237.86K Decreased by -9.23% | Mar 31, 25 |
| 16 | Jennison Associates LLC | 2.48M (3.20%) | -282.87K Decreased by -11.42% | Mar 31, 25 |
| 17 | Assenagon Asset Management SA | 2.14M (2.77%) | 1.41M Increased by +65.74% | Sep 30, 24 |
| 18 | Octagon Capital Advisors LP | 2.09M (2.70%) | -912.98K Decreased by -43.60% | Mar 31, 25 |
| 19 | Slate Path Capital LP | 2.07M (2.67%) | 2.07M Increased by +100.00% | Sep 30, 23 |
| 20 | Cormorant Asset Management, LLC | 2.00M (2.58%) | 690.00K Increased by +34.50% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 9.29M (11.99%) | 809.16K Increased by +8.71% | Mar 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.41M (4.40%) | 72.73K Increased by +2.13% | Apr 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 3.30M (4.26%) | 2.68K Increased by +0.08% | Sep 30, 24 |
| 4 | Vanguard Small Cap Index | 2.65M (3.43%) | 18.50K Increased by +0.70% | Apr 30, 25 |
| 5 | SPDR® S&P Biotech ETF | 2.07M (2.68%) | 12.26K Increased by +0.59% | May 31, 25 |
| 6 | US Small-Cap Growth II Equity Comp | 1.79M (2.31%) | 1.79M Increased by +100.00% | Jun 30, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 1.65M (2.13%) | 17.13K Increased by +1.04% | Apr 30, 25 |
| 8 | Vanguard Small Cap Growth Index Inv | 1.48M (1.91%) | -3.35K Decreased by -0.23% | Apr 30, 25 |
| 9 | Polar Capital Biotech S Inc | 1.43M (1.84%) | -75.00K Decreased by -5.26% | Apr 30, 25 |
| 10 | DWS Vermögensbildungsfonds I LD | 1.32M (1.70%) | -7.00 Decreased by -0.00% | Apr 30, 25 |
| 11 | JPM US Mid Cap Growth-Composite | 1.30M (1.68%) | 294.66K Increased by +22.62% | Sep 30, 24 |
| 12 | JPMorgan Mid Cap Growth I | 1.30M (1.68%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 13 | T. Rowe Price Health Sciences | 1.29M (1.67%) | -29.49K Decreased by -2.28% | Mar 31, 24 |
| 14 | Fidelity® Select Biotechnology | 1.28M (1.65%) | 56.40K Increased by +4.41% | Nov 30, 23 |
| 15 | T. Rowe Price US Mid-Cap Growth Equity | 1.20M (1.54%) | -145.16K Decreased by -12.13% | Sep 30, 24 |
| 16 | T. Rowe Price Small-Cap Stock | 1.09M (1.40%) | -1.60K Decreased by -0.15% | Dec 31, 23 |
| 17 | T. Rowe Price US Small-Cap Core Equity | 1.09M (1.40%) | -1.60K Decreased by -0.15% | Dec 31, 23 |
| 18 | Vanguard Explorer Inv | 1.06M (1.36%) | 69.22K Increased by +6.56% | Mar 31, 25 |
| 19 | Hartford MidCap Y | 1.00M (1.29%) | -676.41K Decreased by -67.49% | Sep 30, 24 |
| 20 | Worldwide Healthcare Ord | 911.00K (1.18%) | 0.00 Increased by 0.00% | Oct 31, 24 |