| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | venBio Select Advisor LLC | 12.22M (14.47%) | 1.11M Increased by +9.09% | Dec 31, 24 |
| 2 | EcoR1 Capital, LLC | 11.89M (14.07%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Wellington Management Company LLP | 11.80M (13.97%) | -3.77M Decreased by -31.91% | Dec 31, 24 |
| 4 | Vanguard Group Inc | 10.05M (11.89%) | 230.45K Increased by +2.29% | Dec 31, 24 |
| 5 | Morgan Stanley - Brokerage Accounts | 9.63M (11.40%) | 6.24M Increased by +64.79% | Dec 31, 24 |
| 6 | JPMorgan Chase & Co | 7.77M (9.20%) | 1.41M Increased by +18.21% | Sep 30, 24 |
| 7 | BlackRock Inc | 6.48M (7.67%) | 285.62K Increased by +4.41% | Dec 31, 24 |
| 8 | State Street Corp | 4.53M (5.36%) | 484.29K Increased by +10.70% | Dec 31, 24 |
| 9 | Deep Track Capital, LP | 4.27M (5.06%) | -125.73K Decreased by -2.94% | Dec 31, 24 |
| 10 | Octagon Capital Advisors LP | 3.01M (3.56%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | T. Rowe Price Investment Management,Inc. | 2.99M (3.53%) | -1.06M Decreased by -35.61% | Sep 30, 24 |
| 12 | State Street Corporation | 2.91M (3.44%) | -5.89K Decreased by -0.20% | Mar 31, 24 |
| 13 | Siren, L.L.C. | 2.82M (3.33%) | 649.03K Increased by +23.05% | Dec 31, 24 |
| 14 | Jennison Associates LLC | 2.76M (3.27%) | 939.29K Increased by +34.03% | Dec 31, 24 |
| 15 | UBS Group AG | 2.59M (3.06%) | 2.27M Increased by +87.83% | Dec 31, 24 |
| 16 | Assenagon Asset Management SA | 2.14M (2.54%) | 1.41M Increased by +65.74% | Sep 30, 24 |
| 17 | FMR Inc | 2.13M (2.52%) | -772.59K Decreased by -36.31% | Dec 31, 24 |
| 18 | BRAIDWELL LP | 2.10M (2.48%) | -1.03M Decreased by -48.90% | Dec 31, 24 |
| 19 | Slate Path Capital LP | 2.07M (2.45%) | 2.07M Increased by +100.00% | Sep 30, 23 |
| 20 | Cormorant Asset Management, LLC | 2.00M (2.37%) | 690.00K Increased by +34.50% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 9.29M (10.99%) | 809.16K Increased by +8.71% | Mar 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.34M (3.95%) | 14.14K Increased by +0.42% | Mar 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 3.30M (3.91%) | 2.68K Increased by +0.08% | Sep 30, 24 |
| 4 | Vanguard Small Cap Index | 2.64M (3.12%) | -63.26K Decreased by -2.40% | Mar 31, 25 |
| 5 | SPDR® S&P Biotech ETF | 2.15M (2.54%) | -37.67K Decreased by -1.75% | Apr 30, 25 |
| 6 | US Small-Cap Growth II Equity Comp | 1.79M (2.12%) | 1.79M Increased by +100.00% | Jun 30, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 1.63M (1.93%) | -15.22K Decreased by -0.93% | Mar 31, 25 |
| 8 | Polar Capital Biotech S Inc | 1.50M (1.78%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Vanguard Small Cap Growth Index Inv | 1.48M (1.76%) | -31.73K Decreased by -2.14% | Mar 31, 25 |
| 10 | DWS Vermögensbildungsfonds I LD | 1.32M (1.56%) | -8.00 Decreased by -0.00% | Mar 31, 25 |
| 11 | JPM US Mid Cap Growth-Composite | 1.30M (1.54%) | 294.66K Increased by +22.62% | Sep 30, 24 |
| 12 | JPMorgan Mid Cap Growth I | 1.30M (1.54%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 13 | T. Rowe Price Health Sciences | 1.29M (1.53%) | -29.49K Decreased by -2.28% | Mar 31, 24 |
| 14 | Fidelity® Select Biotechnology | 1.28M (1.51%) | 56.40K Increased by +4.41% | Nov 30, 23 |
| 15 | T. Rowe Price US Mid-Cap Growth Equity | 1.20M (1.42%) | -145.16K Decreased by -12.13% | Sep 30, 24 |
| 16 | T. Rowe Price Small-Cap Stock | 1.09M (1.29%) | -1.60K Decreased by -0.15% | Dec 31, 23 |
| 17 | T. Rowe Price US Small-Cap Core Equity | 1.09M (1.29%) | -1.60K Decreased by -0.15% | Dec 31, 23 |
| 18 | Vanguard Explorer Inv | 1.06M (1.25%) | 69.22K Increased by +6.56% | Mar 31, 25 |
| 19 | PGIM Jennison Health Sciences Z | 1.03M (1.22%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | Hartford MidCap Y | 1.00M (1.19%) | -676.41K Decreased by -67.49% | Sep 30, 24 |