| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | venBio Select Advisor LLC | 12.22M (14.51%) | 1.11M Increased by +9.09% | Dec 31, 24 |
| 2 | EcoR1 Capital, LLC | 11.89M (14.12%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Wellington Management Company LLP | 11.80M (14.01%) | -3.77M Decreased by -31.91% | Dec 31, 24 |
| 4 | Vanguard Group Inc | 10.05M (11.93%) | 230.45K Increased by +2.29% | Dec 31, 24 |
| 5 | Morgan Stanley - Brokerage Accounts | 9.63M (11.43%) | 6.24M Increased by +64.79% | Dec 31, 24 |
| 6 | JPMorgan Chase & Co | 7.77M (9.23%) | 1.41M Increased by +18.21% | Sep 30, 24 |
| 7 | BlackRock Inc | 6.48M (7.69%) | 285.62K Increased by +4.41% | Dec 31, 24 |
| 8 | State Street Corp | 4.53M (5.37%) | 484.29K Increased by +10.70% | Dec 31, 24 |
| 9 | Deep Track Capital, LP | 4.27M (5.08%) | -125.73K Decreased by -2.94% | Dec 31, 24 |
| 10 | Octagon Capital Advisors LP | 3.01M (3.57%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | T. Rowe Price Investment Management,Inc. | 2.99M (3.55%) | -1.06M Decreased by -35.61% | Sep 30, 24 |
| 12 | State Street Corporation | 2.91M (3.46%) | -5.89K Decreased by -0.20% | Mar 31, 24 |
| 13 | Siren, L.L.C. | 2.82M (3.34%) | 649.03K Increased by +23.05% | Dec 31, 24 |
| 14 | Jennison Associates LLC | 2.76M (3.28%) | 939.29K Increased by +34.03% | Dec 31, 24 |
| 15 | UBS Group AG | 2.59M (3.07%) | 2.27M Increased by +87.83% | Dec 31, 24 |
| 16 | Assenagon Asset Management SA | 2.14M (2.55%) | 1.41M Increased by +65.74% | Sep 30, 24 |
| 17 | FMR Inc | 2.13M (2.53%) | -772.59K Decreased by -36.31% | Dec 31, 24 |
| 18 | BRAIDWELL LP | 2.10M (2.49%) | -1.03M Decreased by -48.90% | Dec 31, 24 |
| 19 | Slate Path Capital LP | 2.07M (2.46%) | 2.07M Increased by +100.00% | Sep 30, 23 |
| 20 | Cormorant Asset Management, LLC | 2.00M (2.38%) | 690.00K Increased by +34.50% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 8.48M (10.07%) | -1.61M Decreased by -19.01% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.32M (3.94%) | 26.28K Increased by +0.79% | Jan 31, 25 |
| 3 | Vanguard Small Cap Index | 2.70M (3.20%) | 4.80K Increased by +0.18% | Jan 31, 25 |
| 4 | SPDR® S&P Biotech ETF | 2.59M (3.07%) | 19.52K Increased by +0.75% | Feb 27, 25 |
| 5 | US Small-Cap Growth II Equity Comp | 1.79M (2.12%) | 1.79M Increased by +100.00% | Jun 30, 23 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 1.65M (1.95%) | 440.00 Increased by +0.03% | Jan 31, 25 |
| 7 | Vanguard Small Cap Growth Index Inv | 1.53M (1.81%) | -2.53K Decreased by -0.17% | Jan 31, 25 |
| 8 | Polar Capital Biotech S Inc | 1.50M (1.78%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | DWS Vermögensbildungsfonds I LD | 1.32M (1.57%) | 1.00 Increased by +0.00% | Dec 31, 24 |
| 10 | JPM US Mid Cap Growth-Composite | 1.30M (1.55%) | 294.66K Increased by +22.62% | Sep 30, 24 |
| 11 | JPMorgan Mid Cap Growth I | 1.30M (1.55%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 12 | T. Rowe Price Health Sciences | 1.29M (1.53%) | -29.49K Decreased by -2.28% | Mar 31, 24 |
| 13 | Fidelity® Select Biotechnology | 1.28M (1.52%) | 56.40K Increased by +4.41% | Nov 30, 23 |
| 14 | T. Rowe Price US Mid-Cap Growth Equity | 1.20M (1.42%) | -145.16K Decreased by -12.13% | Sep 30, 24 |
| 15 | T. Rowe Price Small-Cap Stock | 1.09M (1.29%) | -1.60K Decreased by -0.15% | Dec 31, 23 |
| 16 | T. Rowe Price US Small-Cap Core Equity | 1.09M (1.29%) | -1.60K Decreased by -0.15% | Dec 31, 23 |
| 17 | Jennison Health Sciences Equity | 1.03M (1.22%) | 471.07K Increased by +45.78% | Dec 31, 24 |
| 18 | PGIM Jennison Health Sciences Z | 1.03M (1.22%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 19 | Hartford MidCap Y | 1.00M (1.19%) | -676.41K Decreased by -67.49% | Sep 30, 24 |
| 20 | Vanguard Explorer Inv | 986.55K (1.17%) | 0.00 Increased by 0.00% | Dec 31, 24 |