| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 8.34M (62.08%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Perceptive Advisors LLC | 5.36M (39.90%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Sands Capital Ventures, LLC | 2.12M (15.80%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Citadel Advisors Llc | 2.12M (15.78%) | -20.98K Decreased by -0.99% | Dec 31, 24 |
| 5 | BlackRock Inc | 945.50K (7.04%) | 158.51K Increased by +16.77% | Dec 31, 24 |
| 6 | Wellington Management Company LLP | 888.13K (6.61%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 671.63K (5.00%) | 34.09K Increased by +5.08% | Dec 31, 24 |
| 8 | Marshall Wace Asset Management Ltd | 597.79K (4.45%) | -212.06K Decreased by -35.47% | Dec 31, 24 |
| 9 | NEA Management Company, LLC | 430.25K (3.20%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 10 | Geode Capital Management, LLC | 301.39K (2.24%) | -714.00 Decreased by -0.24% | Dec 31, 24 |
| 11 | Goldman Sachs Group Inc | 237.55K (1.77%) | 39.38K Increased by +16.58% | Dec 31, 24 |
| 12 | State Street Corp | 236.60K (1.76%) | 10.71K Increased by +4.52% | Dec 31, 24 |
| 13 | Federated Hermes Inc | 226.38K (1.68%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 14 | State Street Corporation | 133.28K (0.99%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 15 | Northern Trust Corp | 117.32K (0.87%) | 11.93K Increased by +10.16% | Dec 31, 24 |
| 16 | Exome Asset Management LLC | 116.76K (0.87%) | 116.76K Increased by +100.00% | Sep 30, 24 |
| 17 | Charles Schwab Investment Management Inc | 113.84K (0.85%) | -2.41K Decreased by -2.12% | Dec 31, 24 |
| 18 | Dafna Capital Management LLC | 112.41K (0.84%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 19 | UBS O'Connor LLC | 102.78K (0.77%) | 23.54K Increased by +22.90% | Dec 31, 24 |
| 20 | Bridgeway Capital Management, LLC | 74.60K (0.56%) | -2.38K Decreased by -3.19% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HBM Healthcare Investments AG Ord | 566.65K (4.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 412.43K (3.07%) | 2.97K Increased by +0.72% | Mar 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 387.41K (2.88%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 268.14K (2.00%) | -2.16K Decreased by -0.81% | Apr 29, 25 |
| 5 | Federated Hermes Kaufmann Growth | 219.81K (1.64%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 6 | Federated Hermes Kaufmann R | 219.81K (1.64%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 176.37K (1.31%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | iShares Biotechnology ETF | 138.33K (1.03%) | 316.00 Increased by +0.23% | Apr 30, 25 |
| 9 | Fidelity Small Cap Index | 116.96K (0.87%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 10 | iShares Russell 2000 Value ETF | 112.94K (0.84%) | -385.00 Decreased by -0.34% | Apr 30, 25 |
| 11 | Fidelity® Small Cap Index | 75.50K (0.56%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 12 | Fidelity Extended Market Index | 75.31K (0.56%) | 979.00 Increased by +1.30% | Mar 31, 25 |
| 13 | Bridgeway Ultra-Small Company Market | 73.00K (0.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 64.10K (0.48%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | State St Russell Sm/Mid Cp® Indx SL Cl I | 64.10K (0.48%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Schwab US Small-Cap ETF™ | 64.08K (0.48%) | -28.00 Decreased by -0.04% | Apr 30, 25 |
| 17 | Vanguard Russell 2000 ETF | 55.34K (0.41%) | 1.25K Increased by +2.26% | Mar 31, 25 |
| 18 | A4Investments SICAV SIF ACCI IlanaA2EURH | 54.07K (0.40%) | 22.89K Increased by +42.33% | Mar 31, 25 |
| 19 | Fidelity® Extended Market Index | 52.58K (0.39%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Loncar Cancer Immunotherapy ETF | 46.72K (0.35%) | 0.00 Increased by 0.00% | Apr 30, 24 |