| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 7.53M (10.63%) | 607.61K Increased by +8.07% | Dec 31, 24 |
| 2 | venBio Select Advisor LLC | 5.67M (8.01%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Driehaus Capital Management LLC | 4.52M (6.39%) | -75.13K Decreased by -1.66% | Dec 31, 24 |
| 4 | Wellington Management Company LLP | 3.78M (5.34%) | -65.84K Decreased by -1.74% | Dec 31, 24 |
| 5 | BRAIDWELL LP | 2.91M (4.12%) | 206.71K Increased by +7.09% | Dec 31, 24 |
| 6 | HHG PLC | 2.87M (4.05%) | 314.36K Increased by +10.97% | Dec 31, 24 |
| 7 | COMMODORE CAPITAL LP | 2.74M (3.87%) | 40.00K Increased by +1.46% | Dec 31, 24 |
| 8 | Polar Capital Holdings PLC | 2.70M (3.81%) | 253.01K Increased by +9.38% | Dec 31, 24 |
| 9 | Capital Research & Mgmt Co - Division 3 | 2.55M (3.60%) | -33.96K Decreased by -1.33% | Dec 31, 24 |
| 10 | Capital World Investors | 2.29M (3.24%) | -387.00K Decreased by -16.87% | Dec 31, 24 |
| 11 | BlackRock Inc | 2.11M (2.97%) | -326.00 Decreased by -0.02% | Dec 31, 24 |
| 12 | Paradigm Biocapital Advisors LP | 2.04M (2.89%) | -441.59K Decreased by -21.61% | Jun 30, 24 |
| 13 | Adage Capital Partners Gp LLC | 1.86M (2.63%) | -220.50K Decreased by -11.83% | Dec 31, 24 |
| 14 | Bvf Inc | 1.83M (2.58%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | Pictet Asset Manangement SA | 1.50M (2.11%) | -32.30K Decreased by -2.16% | Dec 31, 24 |
| 16 | AllianceBernstein L.P. | 1.44M (2.04%) | 18.45K Increased by +1.28% | Dec 31, 24 |
| 17 | T. Rowe Price Investment Management,Inc. | 1.44M (2.03%) | -65.98K Decreased by -4.59% | Dec 31, 24 |
| 18 | JPMorgan Chase & Co | 1.36M (1.92%) | -596.67K Decreased by -43.97% | Dec 31, 24 |
| 19 | Rock Springs Capital Management LP | 1.25M (1.77%) | -64.62K Decreased by -5.16% | Dec 31, 24 |
| 20 | Marshall Wace Asset Management Ltd | 1.20M (1.69%) | -189.19K Decreased by -15.83% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 4.83M (6.82%) | -420.69K Decreased by -8.71% | Dec 31, 24 |
| 2 | Vanguard Health Care Inv | 2.54M (3.59%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Polar Capital Biotech S Inc | 1.75M (2.47%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Fidelity Select Health Care | 1.25M (1.77%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 5 | Strategic Advisers Fidelity US TtlStk | 1.07M (1.51%) | 241.18K Increased by +22.51% | Feb 28, 25 |
| 6 | Fidelity Advisor Health Care I | 780.00K (1.10%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 7 | Fidelity Advisor Biotechnology I | 710.76K (1.00%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 8 | Pictet Biotech | 658.54K (0.93%) | 658.54K Increased by +100.00% | Mar 31, 24 |
| 9 | Polar Capital Healthcare Opports Inc | 652.16K (0.92%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 10 | Pictet-Biotech P USD | 635.94K (0.90%) | -10.25K Decreased by -1.61% | Dec 31, 24 |
| 11 | JPMorgan Small Cap Growth A | 614.42K (0.87%) | -6.91K Decreased by -1.12% | Feb 28, 25 |
| 12 | Lord Abbett Developing Growth A | 544.23K (0.77%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 13 | Fidelity Select Biotechnology | 539.63K (0.76%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 14 | Janus Henderson US SMID Cap Growth | 529.57K (0.75%) | -10.88K Decreased by -2.05% | Dec 31, 24 |
| 15 | Janus Henderson US SMID Cap Growth MA | 529.57K (0.75%) | 529.57K Increased by +100.00% | Dec 31, 24 |
| 16 | Janus Henderson Triton D | 526.70K (0.74%) | -2.87K Decreased by -0.55% | Jan 31, 25 |
| 17 | Bridge Builder Small/Mid Cap Growth | 502.26K (0.71%) | 14.12K Increased by +2.81% | Mar 31, 25 |
| 18 | Fidelity Advisor® Health Care I | 500.00K (0.71%) | -40.00K Decreased by -8.00% | Nov 30, 23 |
| 19 | Candriam Eqs L Biotech C USD Cap | 489.08K (0.69%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 20 | Fidelity® Select Biotechnology | 487.33K (0.69%) | -42.60K Decreased by -8.74% | Nov 30, 23 |