| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 8.88M (12.41%) | 596.86K Increased by +6.72% | Jun 30, 25 |
| 2 | venBio Select Advisor LLC | 5.40M (7.54%) | -341.67K Decreased by -6.33% | Jun 30, 25 |
| 3 | BlackRock Inc | 5.37M (7.49%) | 3.33M Increased by +62.05% | Jun 30, 25 |
| 4 | Driehaus Capital Management LLC | 4.34M (6.06%) | -249.21K Decreased by -5.75% | Jun 30, 25 |
| 5 | BRAIDWELL LP | 3.61M (5.04%) | 895.15K Increased by +24.83% | Jun 30, 25 |
| 6 | HHG PLC | 3.58M (5.00%) | 252.64K Increased by +7.06% | Jun 30, 25 |
| 7 | Capital Research & Mgmt Co - Division 3 | 3.18M (4.44%) | 92.82K Increased by +2.92% | Jun 30, 25 |
| 8 | COMMODORE CAPITAL LP | 3.02M (4.23%) | 700.00K Increased by +23.14% | Jun 30, 25 |
| 9 | Polar Capital Holdings PLC | 2.70M (3.78%) | 80.22K Increased by +2.97% | Jun 30, 25 |
| 10 | Capital World Investors | 2.22M (3.11%) | -69.82K Decreased by -3.14% | Mar 31, 25 |
| 11 | Wellington Management Company LLP | 2.17M (3.04%) | -1.61M Decreased by -74.24% | Jun 30, 25 |
| 12 | Paradigm Biocapital Advisors LP | 2.04M (2.85%) | -441.59K Decreased by -21.61% | Jun 30, 24 |
| 13 | Vestal Point Capital LP | 2.00M (2.79%) | 700.00K Increased by +35.00% | Jun 30, 25 |
| 14 | Bvf Inc | 1.83M (2.55%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | Holocene Advisors, LP | 1.81M (2.53%) | 1.81M Increased by +100.00% | Jun 30, 25 |
| 16 | AllianceBernstein L.P. | 1.52M (2.12%) | 189.14K Increased by +12.46% | Jun 30, 25 |
| 17 | Pictet Asset Manangement SA | 1.47M (2.06%) | -3.17K Decreased by -0.21% | Jun 30, 25 |
| 18 | T. Rowe Price Investment Management,Inc. | 1.44M (2.01%) | -65.98K Decreased by -4.59% | Dec 31, 24 |
| 19 | State Street Corp | 1.38M (1.93%) | 1.07M Increased by +77.86% | Jun 30, 25 |
| 20 | Deep Track Capital, LP | 1.35M (1.89%) | 350.00K Increased by +25.93% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 3.83M (5.34%) | -1.48M Decreased by -38.59% | Jun 30, 25 |
| 2 | Polar Capital Biotech S Inc | 2.00M (2.79%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 3 | iShares Russell 2000 ETF | 1.83M (2.56%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 4 | Strategic Advisers Fidelity US TtlStk | 1.77M (2.47%) | 73.48K Increased by +4.16% | Jul 31, 25 |
| 5 | Vanguard Health Care Inv | 1.60M (2.23%) | -942.73K Decreased by -58.94% | Jun 30, 25 |
| 6 | Fidelity Select Health Care | 1.28M (1.79%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 7 | Fidelity Small Cap Index | 762.45K (1.06%) | 762.45K Increased by +100.00% | Jun 30, 25 |
| 8 | Fidelity Advisor Health Care I | 740.00K (1.03%) | -20.00K Decreased by -2.70% | Jul 31, 25 |
| 9 | Fidelity Advisor Biotechnology I | 710.76K (0.99%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | iShares Russell 2000 Growth ETF | 667.62K (0.93%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 11 | Pictet Biotech | 658.54K (0.92%) | 658.54K Increased by +100.00% | Mar 31, 24 |
| 12 | Polar Capital Healthcare Opports Inc | 652.16K (0.91%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 13 | Pictet-Biotech P USD | 625.53K (0.87%) | 7.66K Increased by +1.22% | May 31, 25 |
| 14 | Pictet-Global Megatrend Sel I USD | 555.58K (0.78%) | 124.77K Increased by +22.46% | May 31, 25 |
| 15 | Lord Abbett Developing Growth A | 544.23K (0.76%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 16 | JPMorgan Small Cap Growth A | 537.59K (0.75%) | -5.79K Decreased by -1.08% | Jul 31, 25 |
| 17 | American Century Small Cap Growth Inv | 534.80K (0.75%) | 534.80K Increased by +100.00% | Jun 30, 25 |
| 18 | American Century U.S. Small Cap Growth | 534.80K (0.75%) | 534.80K Increased by +100.00% | Jun 30, 25 |
| 19 | Fidelity Stock Selector Small Cap | 527.88K (0.74%) | 143.90K Increased by +27.26% | Jun 30, 25 |
| 20 | Janus Henderson Triton D | 515.20K (0.72%) | -6.08K Decreased by -1.18% | Jun 30, 25 |