| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 10.82M (11.92%) | 1.90M Increased by +17.55% | Mar 31, 26 |
| 2 | venBio Select Advisor LLC | 5.78M (6.37%) | 353.33K Increased by +6.12% | Mar 31, 26 |
| 3 | BlackRock Inc | 5.64M (6.21%) | 539.83K Increased by +9.57% | Mar 31, 26 |
| 4 | Wellington Management Company LLP | 4.83M (5.32%) | 64.86K Increased by +1.34% | Mar 31, 26 |
| 5 | Driehaus Capital Management LLC | 4.49M (4.95%) | -47.04K Decreased by -1.05% | Mar 31, 26 |
| 6 | Polar Capital Holdings PLC | 4.41M (4.85%) | 1.94M Increased by +44.03% | Mar 31, 26 |
| 7 | HHG PLC | 4.18M (4.60%) | 91.95K Increased by +2.20% | Mar 31, 26 |
| 8 | Capital Research & Mgmt Co - Division 3 | 2.67M (2.95%) | -740.23K Decreased by -27.68% | Mar 31, 26 |
| 9 | Citadel Advisors Llc | 2.65M (2.92%) | 1.33M Increased by +50.20% | Mar 31, 26 |
| 10 | Capital World Investors | 2.22M (2.45%) | -69.82K Decreased by -3.14% | Mar 31, 25 |
| 11 | Paradigm Biocapital Advisors LP | 2.04M (2.25%) | -441.59K Decreased by -21.61% | Jun 30, 24 |
| 12 | Vestal Point Capital LP | 2.00M (2.20%) | 700.00K Increased by +35.00% | Jun 30, 25 |
| 13 | JPMorgan Chase & Co | 1.92M (2.12%) | 429.58K Increased by +22.33% | Mar 31, 26 |
| 14 | Bvf Inc | 1.83M (2.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | COMMODORE CAPITAL LP | 1.80M (1.98%) | -900.00K Decreased by -50.00% | Dec 31, 25 |
| 16 | State Street Corp | 1.72M (1.90%) | 227.98K Increased by +13.25% | Mar 31, 26 |
| 17 | Affinity Asset Advisors, LLC | 1.68M (1.85%) | 425.00K Increased by +25.37% | Mar 31, 26 |
| 18 | Deerfield Management Co | 1.62M (1.78%) | 1.07M Increased by +66.45% | Mar 31, 26 |
| 19 | Holocene Advisors, LP | 1.52M (1.67%) | 236.60K Increased by +15.58% | Mar 31, 26 |
| 20 | Pictet Asset Manangement SA | 1.47M (1.62%) | -3.17K Decreased by -0.21% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 3.50M (3.86%) | -550.85K Decreased by -15.73% | Mar 31, 26 |
| 2 | Vanguard Health Care Inv | 3.21M (3.54%) | -127.83K Decreased by -3.98% | Mar 31, 26 |
| 3 | Strategic Advisers Fidelity US TtlStk | 3.06M (3.38%) | 69.70K Increased by +2.27% | Apr 30, 26 |
| 4 | Polar Capital Biotech S Inc | 2.58M (2.85%) | 173.84K Increased by +6.73% | Apr 30, 26 |
| 5 | iShares Russell 2000 ETF | 2.07M (2.28%) | 19.08K Increased by +0.92% | May 29, 26 |
| 6 | Polar Capital Healthcare Opports Inc | 1.54M (1.70%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 7 | Fidelity Select Health Care | 1.18M (1.30%) | -20.00K Decreased by -1.69% | Apr 30, 26 |
| 8 | Fidelity Small Cap Index | 847.30K (0.93%) | 103.54K Increased by +12.22% | Mar 31, 26 |
| 9 | Fidelity Advisor Biotechnology I | 710.76K (0.78%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 10 | iShares Russell 2000 Growth ETF | 705.19K (0.78%) | -4.59K Decreased by -0.65% | May 29, 26 |
| 11 | iShares Biotechnology ETF | 683.21K (0.75%) | 9.84K Increased by +1.44% | May 29, 26 |
| 12 | Pictet Biotech | 658.54K (0.73%) | 658.54K Increased by +100.00% | Mar 31, 24 |
| 13 | Pictet-Biotech P USD | 625.53K (0.69%) | 7.66K Increased by +1.22% | May 31, 25 |
| 14 | Fidelity Advisor Health Care I | 600.00K (0.66%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 15 | Fidelity Small Cap Growth | 582.62K (0.64%) | 103.69K Increased by +17.80% | Mar 31, 26 |
| 16 | Pictet-Global Megatrend Sel I USD | 555.58K (0.61%) | 124.77K Increased by +22.46% | May 31, 25 |
| 17 | Lord Abbett Developing Growth A | 544.23K (0.60%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 18 | Fidelity Stock Selector Small Cap | 532.18K (0.59%) | -600.00 Decreased by -0.11% | Mar 31, 26 |
| 19 | State St Russell Sm/Mid Cp® Indx SL Cl I | 522.90K (0.58%) | 0.00 Increased by 0.00% | May 31, 26 |
| 20 | Federated Hermes Kaufmann Growth | 522.50K (0.58%) | 182.50K Increased by +34.93% | Mar 31, 26 |