| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 8.92M (11.38%) | 1.34K Increased by +0.02% | Dec 31, 25 |
| 2 | venBio Select Advisor LLC | 5.42M (6.92%) | 24.44K Increased by +0.45% | Dec 31, 25 |
| 3 | BlackRock Inc | 4.77M (6.09%) | -594.38K Decreased by -12.46% | Sep 30, 25 |
| 4 | Wellington Management Company LLP | 4.76M (6.08%) | 1.15M Increased by +24.24% | Dec 31, 25 |
| 5 | Driehaus Capital Management LLC | 4.54M (5.79%) | 369.58K Increased by +8.14% | Dec 31, 25 |
| 6 | HHG PLC | 3.94M (5.03%) | 366.15K Increased by +9.28% | Sep 30, 25 |
| 7 | Capital Research & Mgmt Co - Division 3 | 3.41M (4.36%) | 233.47K Increased by +6.84% | Dec 31, 25 |
| 8 | JPMorgan Chase & Co | 2.80M (3.57%) | 1.54M Increased by +55.09% | Sep 30, 25 |
| 9 | Polar Capital Holdings PLC | 2.47M (3.15%) | -81.07K Decreased by -3.29% | Dec 31, 25 |
| 10 | Capital World Investors | 2.22M (2.84%) | -69.82K Decreased by -3.14% | Mar 31, 25 |
| 11 | Paradigm Biocapital Advisors LP | 2.04M (2.61%) | -441.59K Decreased by -21.61% | Jun 30, 24 |
| 12 | Vestal Point Capital LP | 2.00M (2.55%) | 700.00K Increased by +35.00% | Jun 30, 25 |
| 13 | Bvf Inc | 1.83M (2.33%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | BRAIDWELL LP | 1.83M (2.33%) | -1.78M Decreased by -97.53% | Dec 31, 25 |
| 15 | COMMODORE CAPITAL LP | 1.80M (2.30%) | -900.00K Decreased by -50.00% | Dec 31, 25 |
| 16 | AllianceBernstein L.P. | 1.65M (2.11%) | 135.89K Increased by +8.21% | Sep 30, 25 |
| 17 | Pictet Asset Manangement SA | 1.47M (1.88%) | -3.17K Decreased by -0.21% | Jun 30, 25 |
| 18 | State Street Corp | 1.47M (1.87%) | 86.01K Increased by +5.86% | Sep 30, 25 |
| 19 | T. Rowe Price Investment Management,Inc. | 1.44M (1.83%) | -65.98K Decreased by -4.59% | Dec 31, 24 |
| 20 | Millennium Management LLC | 1.38M (1.77%) | 501.17K Increased by +36.21% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 4.05M (5.17%) | 227.47K Increased by +5.61% | Dec 31, 25 |
| 2 | Vanguard Health Care Inv | 3.34M (4.27%) | 863.22K Increased by +25.82% | Dec 31, 25 |
| 3 | iShares Russell 2000 ETF | 2.09M (2.67%) | -17.11K Decreased by -0.82% | Mar 31, 26 |
| 4 | Strategic Advisers Fidelity US TtlStk | 2.04M (2.61%) | 28.13K Increased by +1.38% | Feb 28, 26 |
| 5 | Fidelity Select Health Care | 1.29M (1.65%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 6 | Polar Capital Healthcare Opports Inc | 907.51K (1.16%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 7 | Polar Capital Biotech S Inc | 750.00K (0.96%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 8 | Fidelity Small Cap Index | 734.83K (0.94%) | -9.96K Decreased by -1.36% | Jan 31, 26 |
| 9 | Fidelity Advisor Biotechnology I | 710.76K (0.91%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 10 | iShares Russell 2000 Growth ETF | 704.12K (0.90%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 11 | Fidelity Advisor Health Care I | 690.00K (0.88%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 12 | Pictet Biotech | 658.54K (0.84%) | 658.54K Increased by +100.00% | Mar 31, 24 |
| 13 | BNP Paribas US Small Cap ClassicC | 635.53K (0.81%) | 28.32K Increased by +4.46% | Feb 28, 26 |
| 14 | Pictet-Biotech P USD | 625.53K (0.80%) | 7.66K Increased by +1.22% | May 31, 25 |
| 15 | iShares Biotechnology ETF | 599.63K (0.77%) | 1.24K Increased by +0.21% | Mar 31, 26 |
| 16 | Pictet-Global Megatrend Sel I USD | 555.58K (0.71%) | 124.77K Increased by +22.46% | May 31, 25 |
| 17 | Lord Abbett Developing Growth A | 544.23K (0.69%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 18 | Fidelity Stock Selector Small Cap | 527.88K (0.67%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 19 | Jennison Health Sciences Equity | 522.45K (0.67%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 20 | PGIM Jennison Health Sciences Z | 522.45K (0.67%) | 0.00 Increased by 0.00% | Feb 28, 26 |