| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 8.29M (11.69%) | 762.21K Increased by +9.20% | Mar 31, 25 |
| 2 | venBio Select Advisor LLC | 5.74M (8.10%) | 75.00K Increased by +1.31% | Mar 31, 25 |
| 3 | Driehaus Capital Management LLC | 4.58M (6.47%) | 64.26K Increased by +1.40% | Mar 31, 25 |
| 4 | Wellington Management Company LLP | 3.79M (5.35%) | 11.59K Increased by +0.31% | Mar 31, 25 |
| 5 | HHG PLC | 3.33M (4.69%) | 458.34K Increased by +13.78% | Mar 31, 25 |
| 6 | Capital Research & Mgmt Co - Division 3 | 3.09M (4.36%) | 541.52K Increased by +17.53% | Mar 31, 25 |
| 7 | BRAIDWELL LP | 2.71M (3.82%) | -204.09K Decreased by -7.53% | Mar 31, 25 |
| 8 | Polar Capital Holdings PLC | 2.62M (3.70%) | -74.62K Decreased by -2.84% | Mar 31, 25 |
| 9 | COMMODORE CAPITAL LP | 2.33M (3.28%) | -415.00K Decreased by -17.85% | Mar 31, 25 |
| 10 | Capital World Investors | 2.22M (3.14%) | -69.82K Decreased by -3.14% | Mar 31, 25 |
| 11 | Paradigm Biocapital Advisors LP | 2.04M (2.88%) | -441.59K Decreased by -21.61% | Jun 30, 24 |
| 12 | BlackRock Inc | 2.04M (2.87%) | -69.11K Decreased by -3.39% | Mar 31, 25 |
| 13 | Adage Capital Partners Gp LLC | 1.91M (2.70%) | 51.28K Increased by +2.68% | Mar 31, 25 |
| 14 | Bvf Inc | 1.83M (2.58%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | Pictet Asset Manangement SA | 1.48M (2.08%) | -18.89K Decreased by -1.28% | Mar 31, 25 |
| 16 | AllianceBernstein L.P. | 1.44M (2.04%) | 18.45K Increased by +1.28% | Dec 31, 24 |
| 17 | T. Rowe Price Investment Management,Inc. | 1.44M (2.03%) | -65.98K Decreased by -4.59% | Dec 31, 24 |
| 18 | Westfield Capital Management Company, L.P. | 1.39M (1.96%) | 234.18K Increased by +16.83% | Mar 31, 25 |
| 19 | JPMorgan Chase & Co | 1.36M (1.92%) | 707.00 Increased by +0.05% | Mar 31, 25 |
| 20 | Affinity Asset Advisors, LLC | 1.33M (1.87%) | 166.94K Increased by +12.57% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 5.30M (7.48%) | 471.78K Increased by +8.90% | Mar 31, 25 |
| 2 | Vanguard Health Care Inv | 2.54M (3.59%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Polar Capital Biotech S Inc | 1.70M (2.40%) | -50.00K Decreased by -2.94% | Apr 30, 25 |
| 4 | Strategic Advisers Fidelity US TtlStk | 1.37M (1.93%) | 296.49K Increased by +21.67% | Mar 31, 25 |
| 5 | Fidelity Select Health Care | 1.28M (1.81%) | 30.00K Increased by +2.34% | Mar 31, 25 |
| 6 | Fidelity Advisor Health Care I | 760.00K (1.07%) | -20.00K Decreased by -2.63% | Mar 31, 25 |
| 7 | Fidelity Advisor Biotechnology I | 710.76K (1.00%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | Pictet Biotech | 658.54K (0.93%) | 658.54K Increased by +100.00% | Mar 31, 24 |
| 9 | Polar Capital Healthcare Opports Inc | 652.16K (0.92%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 10 | JPMorgan Small Cap Growth A | 622.19K (0.88%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 11 | Pictet-Biotech P USD | 621.90K (0.88%) | -24.33K Decreased by -3.91% | Feb 28, 25 |
| 12 | Lord Abbett Developing Growth A | 544.23K (0.77%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 13 | Janus Henderson US SMID Cap Growth MA | 529.57K (0.75%) | 529.57K Increased by +100.00% | Dec 31, 24 |
| 14 | Fidelity Select Biotechnology | 528.03K (0.74%) | -11.60K Decreased by -2.20% | Mar 31, 25 |
| 15 | Janus Henderson Triton D | 521.27K (0.74%) | -5.43K Decreased by -1.04% | Mar 31, 25 |
| 16 | Janus Henderson US SMID Cap Growth | 521.27K (0.74%) | -8.30K Decreased by -1.59% | Mar 31, 25 |
| 17 | Fidelity Advisor® Health Care I | 500.00K (0.71%) | -40.00K Decreased by -8.00% | Nov 30, 23 |
| 18 | Fidelity® Select Biotechnology | 487.33K (0.69%) | -42.60K Decreased by -8.74% | Nov 30, 23 |
| 19 | Fidelity Small Cap Growth | 480.34K (0.68%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 20 | FIAM Small Cap Core Composite | 474.30K (0.67%) | -7.70K Decreased by -1.62% | Dec 31, 24 |