| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 18.20M (24.62%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Adage Capital Partners Gp LLC | 15.02M (20.31%) | 2.50M Increased by +16.65% | Jun 30, 25 |
| 3 | BlackRock Inc | 10.38M (14.05%) | 755.10K Increased by +7.27% | Jun 30, 25 |
| 4 | Maverick Capital Ltd | 8.26M (11.18%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Driehaus Capital Management LLC | 6.53M (8.84%) | 172.92K Increased by +2.65% | Jun 30, 25 |
| 6 | M28 Capital Management LP | 5.66M (7.66%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | T. Rowe Price Associates, Inc. | 5.19M (7.02%) | 1.07M Increased by +20.52% | Jun 30, 25 |
| 8 | Artal Group S A | 4.57M (6.18%) | 514.85K Increased by +11.28% | Jun 30, 24 |
| 9 | Kynam Capital Management, LP | 4.56M (6.17%) | -339.44K Decreased by -7.44% | Jun 30, 25 |
| 10 | 683 Capital Management LLC | 4.10M (5.55%) | 175.00K Increased by +4.27% | Jun 30, 25 |
| 11 | Bellevue Group AG | 4.09M (5.54%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Siren, L.L.C. | 3.70M (5.00%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Vanguard Group Inc | 3.48M (4.70%) | 270.67K Increased by +7.78% | Jun 30, 25 |
| 14 | Loomis, Sayles & Company LP | 3.30M (4.46%) | 859.16K Increased by +26.07% | Jun 30, 25 |
| 15 | Emerald Advisers, LLC | 3.26M (4.41%) | 123.56K Increased by +3.79% | Jun 30, 25 |
| 16 | Geode Capital Management, LLC | 2.76M (3.73%) | 166.98K Increased by +6.05% | Jun 30, 25 |
| 17 | State Street Corp | 2.76M (3.73%) | 338.79K Increased by +12.29% | Jun 30, 25 |
| 18 | PRIMECAP Management Company | 2.47M (3.34%) | -41.67K Decreased by -1.69% | Jun 30, 25 |
| 19 | Artisan Partners Limited Partnership | 2.26M (3.06%) | -105.32K Decreased by -4.65% | Jun 30, 25 |
| 20 | FMR Inc | 2.14M (2.90%) | 317.11K Increased by +14.78% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 4.09M (5.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | iShares Russell 2000 ETF | 2.70M (3.65%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 3 | PRIMECAP Odyssey Aggressive Growth | 2.39M (3.24%) | -46.94K Decreased by -1.96% | Jun 30, 25 |
| 4 | US Small-Cap Growth II Equity Comp | 2.13M (2.88%) | 513.86K Increased by +24.15% | Jun 30, 25 |
| 5 | T. Rowe Price New Horizons | 2.12M (2.87%) | -3.58K Decreased by -0.17% | Jul 31, 25 |
| 6 | Loomis Sayles Small Cap Growth Instl | 1.81M (2.45%) | -41.87K Decreased by -2.31% | Jul 31, 25 |
| 7 | Artisan International Small-Mid Investor | 1.51M (2.05%) | -102.46K Decreased by -6.77% | Jun 30, 25 |
| 8 | Artisan Non-U.S. Small-Mid Growth Comp | 1.51M (2.05%) | -102.46K Decreased by -6.77% | Jun 30, 25 |
| 9 | Fidelity Select Biotechnology | 1.44M (1.95%) | 1.11M Increased by +76.84% | Sep 30, 24 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 1.28M (1.74%) | -575.53K Decreased by -44.84% | Jul 31, 25 |
| 11 | Fidelity Small Cap Index | 1.12M (1.52%) | 145.27K Increased by +12.91% | Jun 30, 25 |
| 12 | T. Rowe Price Health Sciences | 1.07M (1.44%) | -8.01K Decreased by -0.75% | Jul 31, 25 |
| 13 | Polar Capital Biotech S Inc | 1.00M (1.35%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 14 | Emerald Growth A | 962.90K (1.30%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 15 | Fidelity Small Cap Growth | 942.80K (1.28%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | iShares Russell 2000 Growth ETF | 879.02K (1.19%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 17 | iShares Biotechnology ETF | 736.77K (1.00%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 18 | Principal SmallCap Growth I Instl | 701.87K (0.95%) | -1.77K Decreased by -0.25% | Jul 31, 25 |
| 19 | iShares Russell 2000 Value ETF | 674.60K (0.91%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 20 | Heptagon Driehaus US Micro Cap Eq C$ Acc | 652.27K (0.88%) | 36.73K Increased by +5.63% | Jul 31, 25 |