| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 18.20M (20.61%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Adage Capital Partners Gp LLC | 15.02M (17.01%) | 2.50M Increased by +16.65% | Jun 30, 25 |
| 3 | BlackRock Inc | 10.38M (11.76%) | 755.10K Increased by +7.27% | Jun 30, 25 |
| 4 | Maverick Capital Ltd | 8.26M (9.36%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Driehaus Capital Management LLC | 6.53M (7.40%) | 172.92K Increased by +2.65% | Jun 30, 25 |
| 6 | M28 Capital Management LP | 5.66M (6.41%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | T. Rowe Price Associates, Inc. | 5.19M (5.88%) | 1.07M Increased by +20.52% | Jun 30, 25 |
| 8 | Artal Group S A | 4.57M (5.17%) | 514.85K Increased by +11.28% | Jun 30, 24 |
| 9 | Kynam Capital Management, LP | 4.56M (5.16%) | -339.44K Decreased by -7.44% | Jun 30, 25 |
| 10 | 683 Capital Management LLC | 4.10M (4.64%) | 175.00K Increased by +4.27% | Jun 30, 25 |
| 11 | Bellevue Group AG | 4.09M (4.64%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Siren, L.L.C. | 3.70M (4.19%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Vanguard Group Inc | 3.48M (3.94%) | 270.67K Increased by +7.78% | Jun 30, 25 |
| 14 | Loomis, Sayles & Company LP | 3.30M (3.73%) | 859.16K Increased by +26.07% | Jun 30, 25 |
| 15 | Emerald Advisers, LLC | 3.26M (3.69%) | 123.56K Increased by +3.79% | Jun 30, 25 |
| 16 | Geode Capital Management, LLC | 2.76M (3.12%) | 166.98K Increased by +6.05% | Jun 30, 25 |
| 17 | State Street Corp | 2.76M (3.12%) | 338.79K Increased by +12.29% | Jun 30, 25 |
| 18 | PRIMECAP Management Company | 2.47M (2.79%) | -41.67K Decreased by -1.69% | Jun 30, 25 |
| 19 | Artisan Partners Limited Partnership | 2.26M (2.56%) | -105.32K Decreased by -4.65% | Jun 30, 25 |
| 20 | FMR Inc | 2.14M (2.43%) | 317.11K Increased by +14.78% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 4.09M (4.64%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | iShares Russell 2000 ETF | 2.70M (3.06%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 3 | PRIMECAP Odyssey Aggressive Growth | 2.39M (2.71%) | -46.94K Decreased by -1.96% | Jun 30, 25 |
| 4 | US Small-Cap Growth II Equity Comp | 2.13M (2.41%) | 513.86K Increased by +24.15% | Jun 30, 25 |
| 5 | T. Rowe Price New Horizons | 2.12M (2.41%) | -3.58K Decreased by -0.17% | Jul 31, 25 |
| 6 | Loomis Sayles Small Cap Growth Instl | 1.81M (2.05%) | -41.87K Decreased by -2.31% | Jul 31, 25 |
| 7 | Artisan International Small-Mid Investor | 1.51M (1.72%) | -102.46K Decreased by -6.77% | Jun 30, 25 |
| 8 | Artisan Non-U.S. Small-Mid Growth Comp | 1.51M (1.72%) | -102.46K Decreased by -6.77% | Jun 30, 25 |
| 9 | Fidelity Select Biotechnology | 1.44M (1.63%) | 1.11M Increased by +76.84% | Sep 30, 24 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 1.28M (1.45%) | -575.53K Decreased by -44.84% | Jul 31, 25 |
| 11 | Fidelity Small Cap Index | 1.12M (1.27%) | 145.27K Increased by +12.91% | Jun 30, 25 |
| 12 | T. Rowe Price Health Sciences | 1.07M (1.21%) | -8.01K Decreased by -0.75% | Jul 31, 25 |
| 13 | Polar Capital Biotech S Inc | 1.00M (1.13%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 14 | Emerald Growth A | 962.90K (1.09%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 15 | Fidelity Small Cap Growth | 942.80K (1.07%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | iShares Russell 2000 Growth ETF | 879.02K (1.00%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 17 | iShares Biotechnology ETF | 736.77K (0.83%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 18 | Principal SmallCap Growth I Instl | 701.87K (0.79%) | -1.77K Decreased by -0.25% | Jul 31, 25 |
| 19 | iShares Russell 2000 Value ETF | 674.60K (0.76%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 20 | Heptagon Driehaus US Micro Cap Eq C$ Acc | 652.27K (0.74%) | 36.73K Increased by +5.63% | Jul 31, 25 |