| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 26.98M (29.66%) | 8.77M Increased by +32.52% | Mar 30, 26 |
| 2 | GSK PLC | 18.25M (20.06%) | 0.00 Increased by 0.00% | Mar 30, 26 |
| 3 | BlackRock Inc | 14.12M (15.52%) | 1.47M Increased by +10.40% | Mar 30, 26 |
| 4 | Maverick Capital Ltd | 10.16M (11.17%) | 881.16K Increased by +8.67% | Mar 30, 26 |
| 5 | Adage Capital Partners Gp LLC | 9.79M (10.76%) | -4.78M Decreased by -48.86% | Dec 30, 25 |
| 6 | T. Rowe Price Associates, Inc. | 8.70M (9.57%) | 1.30M Increased by +14.90% | Mar 30, 26 |
| 7 | Darwin Global Management, Ltd. | 7.30M (8.02%) | 7.30M Increased by +100.00% | Dec 30, 25 |
| 8 | Driehaus Capital Management LLC | 5.43M (5.97%) | -1.15M Decreased by -21.18% | Mar 30, 26 |
| 9 | Federated Hermes Inc | 5.32M (5.85%) | 572.94K Increased by +10.77% | Mar 30, 26 |
| 10 | FMR Inc | 5.19M (5.71%) | -9.94M Decreased by -191.48% | Mar 30, 26 |
| 11 | 683 Capital Management LLC | 4.90M (5.39%) | 885.00K Increased by +18.06% | Mar 30, 26 |
| 12 | PRIMECAP Management Company | 4.83M (5.31%) | 737.67K Increased by +15.26% | Mar 30, 26 |
| 13 | M28 Capital Management LP | 4.59M (5.04%) | -1.08M Decreased by -23.46% | Mar 30, 26 |
| 14 | Artal Group S A | 4.57M (5.02%) | 514.85K Increased by +11.28% | Jun 29, 24 |
| 15 | Bellevue Group AG | 4.09M (4.50%) | 0.00 Increased by 0.00% | Jun 29, 25 |
| 16 | State Street Corp | 3.67M (4.04%) | 677.95K Increased by +18.45% | Mar 30, 26 |
| 17 | Geode Capital Management, LLC | 3.58M (3.93%) | 408.99K Increased by +11.43% | Mar 30, 26 |
| 18 | Vanguard Group Inc | 3.57M (3.93%) | 433.91K Increased by +12.14% | Dec 30, 25 |
| 19 | The Goldman Sachs Group Inc | 2.85M (3.14%) | 728.95K Increased by +25.54% | Dec 30, 25 |
| 20 | Affinity Asset Advisors, LLC | 2.70M (2.97%) | 600.00K Increased by +22.22% | Dec 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 4.11M (4.52%) | 348.89K Increased by +8.49% | Jun 29, 26 |
| 2 | BB Biotech AG Ord | 4.09M (4.50%) | 0.00 Increased by 0.00% | Sep 29, 25 |
| 3 | iShares Russell 2000 ETF | 3.58M (3.94%) | -2.60K Decreased by -0.07% | Jul 29, 26 |
| 4 | Federated Hermes Kaufmann Growth | 2.48M (2.73%) | -331.93K Decreased by -13.38% | Mar 30, 26 |
| 5 | Federated Hermes Kaufmann R | 2.48M (2.73%) | -331.93K Decreased by -13.38% | Mar 30, 26 |
| 6 | US Small-Cap Growth II Equity Comp | 2.29M (2.51%) | -2.34K Decreased by -0.10% | Mar 30, 26 |
| 7 | T. Rowe Price New Horizons | 2.29M (2.51%) | -1.03K Decreased by -0.04% | Apr 29, 26 |
| 8 | Fidelity Small Cap Growth | 2.06M (2.26%) | 179.10K Increased by +8.70% | Feb 27, 26 |
| 9 | Fidelity Growth Compy Commingled Pl S | 1.98M (2.18%) | 1.54K Increased by +0.08% | May 30, 26 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 1.75M (1.93%) | 113.39K Increased by +6.47% | Jun 29, 26 |
| 11 | Fidelity Growth Company Fund | 1.66M (1.82%) | -2.05K Decreased by -0.12% | Jun 29, 26 |
| 12 | Federated Hermes Kaufmann Small Cap A | 1.64M (1.80%) | -235.07K Decreased by -14.36% | Mar 30, 26 |
| 13 | Federated Hermes Kaufmann Small Cap Grow | 1.64M (1.80%) | -235.07K Decreased by -14.36% | Mar 30, 26 |
| 14 | Fidelity Select Health Care | 1.60M (1.76%) | -1.40M Decreased by -87.50% | Feb 27, 26 |
| 15 | Fidelity Advisor Health Care I | 1.55M (1.70%) | 90.00K Increased by +5.81% | Jan 30, 26 |
| 16 | BlackRock Advantage Small Cap Core Instl | 1.52M (1.67%) | 217.71K Increased by +14.36% | Jun 29, 26 |
| 17 | Artisan International Small-Mid Investor | 1.51M (1.66%) | -102.46K Decreased by -6.77% | Jun 29, 25 |
| 18 | Artisan Non-U.S. Small-Mid Growth Comp | 1.51M (1.66%) | -102.46K Decreased by -6.77% | Jun 29, 25 |
| 19 | Fidelity Select Biotechnology | 1.44M (1.58%) | 1.11M Increased by +76.84% | Sep 29, 24 |
| 20 | T. Rowe Price Integrated US Sm Gr Eq | 1.41M (1.55%) | 0.00 Increased by 0.00% | Apr 29, 26 |