| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 4.17M (12.12%) | 4.17M Increased by +100.00% | Sep 30, 25 |
| 2 | Orbimed Advisors, LLC | 3.06M (8.90%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | TCG Crossover Management, LLC | 2.68M (7.78%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Bvf Inc | 2.00M (5.82%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Nantahala Capital Management, LLC | 1.98M (5.75%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 1.82M (5.31%) | 137.00K Increased by +7.51% | Dec 31, 25 |
| 7 | COMMODORE CAPITAL LP | 1.57M (4.58%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 8 | Great Point Partners LLC | 674.08K (1.96%) | -855.26K Decreased by -126.88% | Sep 30, 24 |
| 9 | ADAR1 Capital Management LLC | 623.58K (1.81%) | 510.51K Increased by +81.87% | Dec 31, 25 |
| 10 | StemPoint Capital LP | 616.75K (1.79%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 11 | Acadian Asset Management LLC | 589.66K (1.71%) | 589.66K Increased by +100.00% | Mar 31, 26 |
| 12 | Soleus Capital Management, L.P. | 550.00K (1.60%) | 550.00K Increased by +100.00% | Sep 30, 25 |
| 13 | JPMorgan Chase & Co | 543.65K (1.58%) | -205.21K Decreased by -37.75% | Sep 30, 25 |
| 14 | Jane Street Group LLC | 527.13K (1.53%) | 224.44K Increased by +42.58% | Dec 31, 25 |
| 15 | Almitas Capital LLC | 522.80K (1.52%) | 261.40K Increased by +50.00% | Sep 30, 25 |
| 16 | Ikarian Capital, LLC | 519.08K (1.51%) | -101.79K Decreased by -19.61% | Dec 31, 25 |
| 17 | Sphera Funds Management Ltd. | 447.94K (1.30%) | -342.61K Decreased by -76.49% | Jun 30, 25 |
| 18 | BlackRock Inc | 422.76K (1.23%) | -369.00 Decreased by -0.09% | Dec 31, 25 |
| 19 | Geode Capital Management, LLC | 352.84K (1.03%) | 54.56K Increased by +15.46% | Dec 31, 25 |
| 20 | Luminus Management, LLC | 350.00K (1.02%) | 350.00K Increased by +100.00% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 1.28M (3.72%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.16M (3.38%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Biotech Growth Ord | 808.70K (2.35%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 413.75K (1.20%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | AdvisorShares Psychedelics ETF | 383.70K (1.12%) | 5.86K Increased by +1.53% | Apr 30, 26 |
| 6 | Fidelity Extended Market Index | 267.11K (0.78%) | 26.49K Increased by +9.92% | Mar 31, 26 |
| 7 | iShares Micro-Cap ETF | 98.43K (0.29%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 8 | DFA US Small Cap I | 74.27K (0.22%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 9 | Blackrock Extended Mkt Fund CF | 71.01K (0.21%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 10 | Extended Equity Market Fund B | 71.01K (0.21%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 11 | Extended Equity Market Fund E | 71.01K (0.21%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 12 | BlackRock Extended Equity Market K | 61.89K (0.18%) | -26.00 Decreased by -0.04% | Sep 30, 24 |
| 13 | BlackRock Extended Equity Market Fund K | 60.46K (0.18%) | -443.00 Decreased by -0.73% | Mar 31, 26 |
| 14 | Extended Equity Market Fund K | 60.46K (0.18%) | -443.00 Decreased by -0.73% | Mar 31, 26 |
| 15 | A4Investments SICAV SIF ACCI IlanaA2EURH | 60.00K (0.17%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 16 | PGIM US Micro Cap Quant Equity | 53.10K (0.15%) | 47.00K Increased by +88.51% | Mar 31, 26 |
| 17 | Spartan Extended Market Index Pool F | 51.60K (0.15%) | 17.44K Increased by +33.80% | Mar 31, 26 |
| 18 | Fidelity Series Total Market Index | 48.90K (0.14%) | 8.84K Increased by +18.08% | Mar 31, 26 |
| 19 | Fidelity Total Market Index | 46.96K (0.14%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | NT Ext Equity Mkt Idx Fd - L | 43.62K (0.13%) | 0.00 Increased by 0.00% | Mar 31, 26 |