| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 4.17M (12.33%) | 4.17M Increased by +100.00% | Sep 30, 25 |
| 2 | Orbimed Advisors, LLC | 3.06M (9.06%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | TCG Crossover Management, LLC | 2.68M (7.92%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | Bvf Inc | 2.00M (5.92%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Nantahala Capital Management, LLC | 1.98M (5.86%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 1.82M (5.40%) | 137.00K Increased by +7.51% | Dec 31, 25 |
| 7 | COMMODORE CAPITAL LP | 1.57M (4.66%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 8 | Great Point Partners LLC | 674.08K (2.00%) | -855.26K Decreased by -126.88% | Sep 30, 24 |
| 9 | ADAR1 Capital Management LLC | 623.58K (1.85%) | 510.51K Increased by +81.87% | Dec 31, 25 |
| 10 | StemPoint Capital LP | 616.75K (1.83%) | -1.87M Decreased by -303.52% | Dec 31, 25 |
| 11 | Soleus Capital Management, L.P. | 550.00K (1.63%) | 550.00K Increased by +100.00% | Sep 30, 25 |
| 12 | JPMorgan Chase & Co | 543.65K (1.61%) | -205.21K Decreased by -37.75% | Sep 30, 25 |
| 13 | Jane Street Group LLC | 527.13K (1.56%) | 224.44K Increased by +42.58% | Dec 31, 25 |
| 14 | Almitas Capital LLC | 522.80K (1.55%) | 261.40K Increased by +50.00% | Sep 30, 25 |
| 15 | Ikarian Capital, LLC | 519.08K (1.54%) | -101.79K Decreased by -19.61% | Dec 31, 25 |
| 16 | Sphera Funds Management Ltd. | 447.94K (1.33%) | -342.61K Decreased by -76.49% | Jun 30, 25 |
| 17 | BlackRock Inc | 423.13K (1.25%) | 6.24K Increased by +1.47% | Sep 30, 25 |
| 18 | Geode Capital Management, LLC | 352.84K (1.04%) | 54.56K Increased by +15.46% | Dec 31, 25 |
| 19 | Luminus Management, LLC | 350.00K (1.04%) | 350.00K Increased by +100.00% | Dec 31, 25 |
| 20 | Diadema Partners LP | 349.79K (1.04%) | -54.13K Decreased by -15.48% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 1.28M (3.79%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.16M (3.44%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 3 | Biotech Growth Ord | 808.70K (2.39%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 413.75K (1.22%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 5 | AdvisorShares Psychedelics ETF | 277.11K (0.82%) | 0.00 Increased by 0.00% | Feb 27, 26 |
| 6 | Fidelity Extended Market Index | 198.69K (0.59%) | -688.00 Decreased by -0.35% | Jan 31, 26 |
| 7 | iShares Micro-Cap ETF | 78.44K (0.23%) | 78.44K Increased by +100.00% | Feb 28, 26 |
| 8 | DFA US Small Cap I | 74.27K (0.22%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 9 | Blackrock Extended Mkt Fund CF | 71.01K (0.21%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 10 | BlackRock Extended Equity Market K | 61.89K (0.18%) | -26.00 Decreased by -0.04% | Sep 30, 24 |
| 11 | Extended Equity Market Fund K | 60.91K (0.18%) | 40.00 Increased by +0.07% | Dec 31, 25 |
| 12 | A4Investments SICAV SIF ACCI IlanaA2EURH | 60.00K (0.18%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 13 | Fidelity Total Market Index | 46.96K (0.14%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 14 | NT Ext Equity Mkt Idx Fd - L | 43.62K (0.13%) | 16.36K Increased by +37.52% | Dec 31, 25 |
| 15 | Fidelity® Extended Market Index | 43.29K (0.13%) | 27.32K Increased by +63.10% | Nov 30, 23 |
| 16 | Fidelity Series Total Market Index | 35.53K (0.11%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 17 | Spartan Extended Market Index Pool F | 34.16K (0.10%) | 688.00 Increased by +2.01% | Jan 31, 26 |
| 18 | Avantis US Small Cap Equity ETF | 31.24K (0.09%) | 0.00 Increased by 0.00% | Aug 30, 25 |
| 19 | Vifag 2002 SICAV | 30.00K (0.09%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 20 | DFA US Micro Cap I | 29.11K (0.09%) | 0.00 Increased by 0.00% | Jan 31, 26 |