| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 4.17M (11.67%) | 4.17M Increased by +100.00% | Sep 30, 25 |
| 2 | Orbimed Advisors, LLC | 3.06M (8.57%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | TCG Crossover Management, LLC | 2.68M (7.50%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Bvf Inc | 2.00M (5.60%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Nantahala Capital Management, LLC | 1.98M (5.54%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 1.82M (5.11%) | 137.00K Increased by +7.51% | Dec 31, 25 |
| 7 | COMMODORE CAPITAL LP | 1.57M (4.41%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 8 | Vanguard Capital Management, LLC | 1.57M (4.41%) | 1.57M Increased by +100.00% | Mar 31, 26 |
| 9 | StemPoint Capital LP | 1.23M (3.45%) | 616.75K Increased by +50.00% | Mar 31, 26 |
| 10 | ADAR1 Capital Management LLC | 751.14K (2.10%) | 127.57K Increased by +16.98% | Mar 31, 26 |
| 11 | Great Point Partners LLC | 674.08K (1.89%) | -855.26K Decreased by -126.88% | Sep 30, 24 |
| 12 | Acadian Asset Management LLC | 589.66K (1.65%) | 589.66K Increased by +100.00% | Mar 31, 26 |
| 13 | Soleus Capital Management, L.P. | 550.00K (1.54%) | 550.00K Increased by +100.00% | Sep 30, 25 |
| 14 | JPMorgan Chase & Co | 543.65K (1.52%) | -205.21K Decreased by -37.75% | Sep 30, 25 |
| 15 | Almitas Capital LLC | 522.80K (1.46%) | 261.40K Increased by +50.00% | Sep 30, 25 |
| 16 | Ikarian Capital, LLC | 519.08K (1.45%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 17 | Two Sigma Investments LLC | 469.62K (1.32%) | 274.05K Increased by +58.36% | Mar 31, 26 |
| 18 | Geode Capital Management, LLC | 453.39K (1.27%) | 100.56K Increased by +22.18% | Mar 31, 26 |
| 19 | BlackRock Inc | 448.51K (1.26%) | 25.75K Increased by +5.74% | Mar 31, 26 |
| 20 | Sphera Funds Management Ltd. | 447.94K (1.25%) | -342.61K Decreased by -76.49% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 1.28M (3.58%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.16M (3.25%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 3 | Biotech Growth Ord | 808.70K (2.26%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 413.75K (1.16%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 5 | AdvisorShares Psychedelics ETF | 397.73K (1.11%) | 0.00 Increased by 0.00% | May 29, 26 |
| 6 | Fidelity Extended Market Index | 266.14K (0.75%) | -972.00 Decreased by -0.37% | Apr 30, 26 |
| 7 | iShares Micro-Cap ETF | 97.14K (0.27%) | 0.00 Increased by 0.00% | May 29, 26 |
| 8 | DFA US Small Cap I | 74.27K (0.21%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 9 | Blackrock Extended Mkt Fund CF | 71.01K (0.20%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 10 | Extended Equity Market Fund B | 71.01K (0.20%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 11 | Extended Equity Market Fund E | 71.01K (0.20%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 12 | BlackRock Extended Equity Market K | 61.89K (0.17%) | -26.00 Decreased by -0.04% | Sep 30, 24 |
| 13 | BlackRock Extended Equity Market Fund K | 60.46K (0.17%) | -443.00 Decreased by -0.73% | Mar 31, 26 |
| 14 | Extended Equity Market Fund K | 60.46K (0.17%) | -443.00 Decreased by -0.73% | Mar 31, 26 |
| 15 | A4Investments SICAV SIF ACCI IlanaA2EURH | 60.00K (0.17%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 16 | PGIM US Micro Cap Quant Equity | 53.10K (0.15%) | 47.00K Increased by +88.51% | Mar 31, 26 |
| 17 | Spartan Extended Market Index Pool F | 52.57K (0.15%) | 972.00 Increased by +1.85% | Apr 30, 26 |
| 18 | Fidelity Series Total Market Index | 48.90K (0.14%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 19 | Fidelity Total Market Index | 46.96K (0.13%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 20 | NT Ext Equity Mkt Idx Fd - L | 43.62K (0.12%) | 0.00 Increased by 0.00% | Mar 31, 26 |