Health Care [ 6/12 ] | Biotechnology [ 45/74 ]
NASDAQ | Common Stock
Vigil Neuroscience, Inc., a clinical-stage biotechnology company, focuses on developing treatments for rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain.
Its lead candidate is VGL101(Iluzanebart), a human monoclonal antibody agonist targeting human triggering receptor expressed on myeloid cells 2 and is in a Phase 2 trial in patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rare and fatal neurodegenerative disease.
The company is also developing VG-3927, an orally-available small molecule TREM2 agonist to treat common neurodegenerative diseases associated with microglial dysfunction, with an initial focus on Alzheimer's disease in genetically defined subpopulations, which is being evaluated in a Phase 1 clinical trial.
It has license agreement with Amgen Inc. to commercially develop, manufacture, use, distribute, and sell therapeutic products containing compounds that bind to TREM2.
The company was incorporated in 2020 and is headquartered in Watertown, Massachusetts.
| Reported date | EPSChange YoY | EstimateSurprise |
|---|---|---|
| May 9, 24 | 0.00 Increased by +100.00% | -0.55 Increased by +100.00% |
| Mar 26, 24 | -0.57 Decreased by -18.75% | -0.53 Decreased by -7.55% |
| Nov 7, 23 | -0.53 Increased by 0.00% | -0.57 Increased by +7.02% |
| Aug 8, 23 | -0.52 Increased by +13.33% | -0.54 Increased by +3.70% |
| May 10, 23 | -0.51 Increased by +12.07% | -0.53 Increased by +3.77% |
| Mar 21, 23 | -0.48 Increased by +94.20% | -0.58 Increased by +17.24% |
| Nov 10, 22 | -0.53 Decreased by -253.33% | -0.60 Increased by +11.67% |
| Aug 8, 22 | -0.60 | -0.67 Increased by +10.45% |
| Fiscal ending date | RevenueChange YoY | IncomeChange YoY | ProfitChange YoY |
|---|---|---|---|
| Mar 31, 24 | N/A Decreased by N/A% | -19.94 M Decreased by -6.35% | - - |
| Dec 31, 23 | 1.93 M Increased by +N/A% | -22.17 M Decreased by -254.68% | Decreased by -1.15 K% Decreased by N/A% |
| Sep 30, 23 | 0.00 Decreased by N/A% | -20.50 M Decreased by -18.04% | Decreased by N/A% Decreased by N/A% |
| Jun 30, 23 | 0.00 Decreased by N/A% | -20.17 M Decreased by -18.75% | Decreased by N/A% Decreased by N/A% |
| Mar 31, 23 | 0.00 Decreased by N/A% | -18.75 M Decreased by -22.26% | Decreased by N/A% Decreased by N/A% |
| Dec 31, 22 | 0.00 Decreased by N/A% | 14.34 M Increased by +210.40% | Increased by +N/A% Decreased by N/A% |
| Sep 30, 22 | 0.00 Decreased by N/A% | -17.36 M Decreased by -61.67% | Decreased by N/A% Decreased by N/A% |
| Jun 30, 22 | 0.00 Decreased by N/A% | -16.99 M Decreased by -49.45% | Decreased by N/A% Decreased by N/A% |