| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 4.54M (12.27%) | 709.10K Increased by +15.61% | Jun 30, 25 |
| 2 | UBS Asset Mgmt Americas Inc | 4.36M (11.77%) | 2.98M Increased by +68.42% | Mar 31, 25 |
| 3 | RA Capital Management, LLC | 3.21M (8.66%) | 3.21M Increased by +100.00% | Mar 31, 25 |
| 4 | BlackRock Inc | 2.42M (6.54%) | -43.75K Decreased by -1.81% | Mar 31, 25 |
| 5 | MENORA MIVTACHIM HOLDINGS LIMITED | 2.30M (6.22%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Vestal Point Capital LP | 2.15M (5.81%) | 522.96K Increased by +24.29% | Mar 31, 25 |
| 7 | The Toronto-Dominion Bank | 1.75M (4.72%) | 1.75M Increased by +100.00% | Mar 31, 25 |
| 8 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.38M (3.73%) | 260.69K Increased by +18.87% | Mar 31, 25 |
| 9 | Nantahala Capital Management, LLC | 1.36M (3.68%) | -8.24K Decreased by -0.60% | Mar 31, 25 |
| 10 | Adage Capital Partners Gp LLC | 1.28M (3.45%) | -1.65M Decreased by -129.29% | Mar 31, 25 |
| 11 | UBS Group AG | 1.17M (3.17%) | 250.39K Increased by +21.34% | Mar 31, 25 |
| 12 | Rosalind Advisors, Inc. | 950.00K (2.57%) | 80.00K Increased by +8.42% | Mar 31, 25 |
| 13 | Morgan Stanley - Brokerage Accounts | 857.73K (2.32%) | 90.43K Increased by +10.54% | Mar 31, 25 |
| 14 | Jefferies Financial Group Inc | 815.00K (2.20%) | -150.93K Decreased by -18.52% | Mar 31, 25 |
| 15 | State Street Corp | 795.01K (2.15%) | -13.04K Decreased by -1.64% | Mar 31, 25 |
| 16 | Migdal Insurance & Financial Holdings Ltd | 786.47K (2.12%) | 100.00K Increased by +12.72% | Mar 31, 25 |
| 17 | Kynam Capital Management, LP | 656.57K (1.77%) | 631.57K Increased by +96.19% | Jun 30, 25 |
| 18 | Wildcat Capital Management, LLC | 495.61K (1.34%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Dafna Capital Management LLC | 492.51K (1.33%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | Geode Capital Management, LLC | 473.33K (1.28%) | 11.43K Increased by +2.41% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BioPharma Credit Ord | 4.69M (12.68%) | 4.69M Increased by +100.00% | Dec 31, 24 |
| 2 | UBS (Lux) Digital Health Equity SB USD | 1.32M (3.56%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 3 | UBS Lux Dgtl Hlth Eq Fd seeding P acc | 1.25M (3.37%) | 0.00 Increased by 0.00% | May 31, 25 |
| 4 | CS (Lux) Digital Health Equity SB USD | 1.20M (3.24%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 5 | iShares Russell 2000 ETF | 868.93K (2.35%) | -16.48K Decreased by -1.90% | Jul 31, 25 |
| 6 | International Biotechnology Ord | 427.15K (1.15%) | -34.85K Decreased by -8.16% | May 31, 25 |
| 7 | MEDICAL BioHealth EUR Acc | 421.71K (1.14%) | 127.00K Increased by +30.12% | Aug 31, 24 |
| 8 | Fidelity Small Cap Index | 387.38K (1.05%) | -2.63K Decreased by -0.68% | May 31, 25 |
| 9 | iShares Russell 2000 Growth ETF | 264.63K (0.71%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | State St Russell Sm/Mid Cp® Indx NL Cl C | 262.40K (0.71%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 11 | State St Russell Sm/Mid Cp® Indx SL Cl I | 262.40K (0.71%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | iShares Biotechnology ETF | 240.40K (0.65%) | 2.06K Increased by +0.86% | Jul 31, 25 |
| 13 | Fidelity® Small Cap Index | 189.44K (0.51%) | 5.40K Increased by +2.85% | Oct 31, 23 |
| 14 | Vanguard Russell 2000 ETF | 175.92K (0.48%) | -11.93K Decreased by -6.78% | Jul 31, 25 |
| 15 | SPDR® Portfolio Developed Wld ex-US ETF | 156.96K (0.42%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 16 | AlphaCentric LifeSci Healthcare I | 143.90K (0.39%) | -11.10K Decreased by -7.72% | Mar 31, 24 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 134.50K (0.36%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 18 | ARK Israel Innovative Technology ETF | 129.01K (0.35%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | APO Medical Opportunities R | 98.89K (0.27%) | -78.50K Decreased by -79.38% | Sep 30, 24 |
| 20 | Schwab Small Cap Index | 92.88K (0.25%) | 0.00 Increased by 0.00% | Jul 31, 25 |