| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 8.19M (7.12%) | 2.64M Increased by +32.25% | Dec 31, 25 |
| 2 | Soleus Capital Management, L.P. | 8.13M (7.06%) | -40.00K Decreased by -0.49% | Sep 30, 25 |
| 3 | Morgan Stanley - Brokerage Accounts | 7.95M (6.90%) | 356.51K Increased by +4.49% | Dec 31, 25 |
| 4 | Deep Track Capital, LP | 7.50M (6.51%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 5 | Adage Capital Partners Gp LLC | 5.55M (4.82%) | 1.61M Increased by +29.03% | Dec 31, 25 |
| 6 | Vanguard Group Inc | 5.52M (4.80%) | 964.03K Increased by +17.45% | Dec 31, 25 |
| 7 | Vivo Capital, LLC | 5.35M (4.64%) | -1.55M Decreased by -28.97% | Dec 31, 25 |
| 8 | Vestal Point Capital LP | 4.50M (3.91%) | 4.50M Increased by +100.00% | Dec 31, 25 |
| 9 | venBio Select Advisor LLC | 4.35M (3.78%) | 4.35M Increased by +100.00% | Dec 31, 25 |
| 10 | HHG PLC | 3.38M (2.94%) | 3.38M Increased by +100.00% | Dec 31, 25 |
| 11 | Citadel Advisors Llc | 3.17M (2.75%) | 1.58M Increased by +49.81% | Dec 31, 25 |
| 12 | Schonfeld Strategic Advisors LLC | 3.05M (2.65%) | -794.98K Decreased by -26.07% | Jun 30, 25 |
| 13 | Capitolis Liquid Global Markets LLC | 3.05M (2.65%) | 3.05M Increased by +100.00% | Dec 31, 25 |
| 14 | BRAIDWELL LP | 2.84M (2.47%) | 997.70K Increased by +35.13% | Sep 30, 23 |
| 15 | Holocene Advisors, LP | 2.78M (2.41%) | 2.78M Increased by +100.00% | Dec 31, 25 |
| 16 | Franklin Resources Inc | 2.73M (2.37%) | 1.45M Increased by +53.23% | Dec 31, 25 |
| 17 | Lord, Abbett & Co LLC | 2.71M (2.36%) | 2.71M Increased by +100.00% | Dec 31, 25 |
| 18 | Nuveen Asset Management, LLC | 2.63M (2.29%) | 617.01K Increased by +23.43% | Dec 31, 24 |
| 19 | Candriam Luxembourg S.C.A. | 2.37M (2.06%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 20 | Orbimed Advisors, LLC | 2.15M (1.87%) | -5.41M Decreased by -251.23% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.29M (2.85%) | 86.47K Increased by +2.63% | Mar 31, 26 |
| 2 | iShares Russell 2000 ETF | 2.23M (1.94%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 3 | Vanguard US Total Market Shares ETF | 2.09M (1.81%) | 792.70K Increased by +38.01% | Sep 30, 24 |
| 4 | Fidelity® Small Cap Growth | 1.98M (1.72%) | -2.40K Decreased by -0.12% | Oct 31, 23 |
| 5 | Fidelity Small Cap Growth | 1.97M (1.71%) | 0.00 Increased by 0.00% | May 31, 24 |
| 6 | Lord Abbett & Co. Growth Equity- SA | 1.59M (1.38%) | 601.50K Increased by +37.86% | Mar 31, 26 |
| 7 | Lord Abbett Growth Leaders I | 1.59M (1.38%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | American Funds SMALLCAP World A | 1.42M (1.24%) | 364.50K Increased by +25.59% | Mar 31, 26 |
| 9 | HBM Healthcare Investments AG Ord | 1.15M (1.00%) | 478.02K Increased by +41.57% | Dec 31, 25 |
| 10 | Candriam Eqs L Biotech C USD Cap | 1.11M (0.96%) | 26.75K Increased by +2.41% | Oct 31, 25 |
| 11 | Pictet-Biotech P USD | 1.08M (0.94%) | 1.08M Increased by +100.00% | Jan 31, 26 |
| 12 | Fidelity Select Biotechnology | 1.08M (0.94%) | -27.10K Decreased by -2.51% | Feb 28, 26 |
| 13 | CREF Stock R1 | 1.08M (0.94%) | -160.00K Decreased by -14.86% | Feb 28, 25 |
| 14 | T. Rowe Price New Horizons | 1.04M (0.90%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | US Small-Cap Growth II Equity Comp | 1.04M (0.90%) | 529.45K Increased by +50.83% | Dec 31, 24 |
| 16 | Franklin Biotechnology Discv A(acc)USD | 1.04M (0.90%) | -311.36K Decreased by -29.96% | Mar 31, 26 |
| 17 | Lord Abbett Growth Leaders SMA | 987.23K (0.86%) | 987.23K Increased by +100.00% | Dec 31, 25 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 961.64K (0.84%) | 23.49K Increased by +2.44% | Mar 31, 26 |
| 19 | Fidelity Small Cap Index | 839.46K (0.73%) | 8.74K Increased by +1.04% | Feb 28, 26 |
| 20 | iShares Russell 2000 Value ETF | 812.30K (0.71%) | 0.00 Increased by 0.00% | Apr 30, 26 |