| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Adage Capital Partners Gp LLC | 6.31M (13.27%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Orbimed Advisors, LLC | 6.31M (13.27%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | Redmile Group, LLC | 5.54M (11.65%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | NEXTBio Capital Management LP | 3.15M (6.63%) | 3.15M Increased by +100.00% | Dec 31, 25 |
| 5 | Prosight Management, LP | 2.38M (5.01%) | -3.07M Decreased by -128.90% | Dec 31, 25 |
| 6 | Vanguard Group Inc | 2.38M (5.00%) | 249.34K Increased by +10.49% | Dec 31, 25 |
| 7 | T. Rowe Price Investment Management,Inc. | 1.86M (3.92%) | 1.86M Increased by +100.00% | Dec 31, 25 |
| 8 | Franklin Resources Inc | 1.57M (3.30%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | Clark Estates Inc | 1.48M (3.10%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | 683 Capital Management LLC | 1.39M (2.92%) | -142.22K Decreased by -10.23% | Dec 31, 25 |
| 11 | Pinnacle Associates Inc | 1.35M (2.84%) | -38.09K Decreased by -2.82% | Dec 31, 25 |
| 12 | Bank of America Corp | 1.13M (2.38%) | 1.09M Increased by +96.74% | Sep 30, 25 |
| 13 | Point72 Asset Management, L.P. | 1.07M (2.25%) | 1.07M Increased by +100.00% | Dec 31, 25 |
| 14 | LAURION CAPITAL MANAGEMENT LP | 661.04K (1.39%) | 155.04K Increased by +23.45% | Mar 31, 24 |
| 15 | MAVEN SECURITIES Ltd | 633.88K (1.33%) | 633.88K Increased by +100.00% | Dec 31, 23 |
| 16 | Geode Capital Management, LLC | 618.28K (1.30%) | 150.32K Increased by +24.31% | Dec 31, 25 |
| 17 | Aberdeen Group PLC | 531.18K (1.12%) | 436.67K Increased by +82.21% | Dec 31, 25 |
| 18 | Takeda Pharmaceutical Co Ltd | 515.62K (1.08%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 19 | Marshall Wace Asset Management Ltd | 489.91K (1.03%) | -166.74K Decreased by -34.03% | Dec 31, 25 |
| 20 | Millennium Management LLC | 477.41K (1.00%) | -213.49K Decreased by -44.72% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Small-Cap Value | 2.83M (5.95%) | 862.80K Increased by +30.49% | Mar 31, 26 |
| 2 | Fidelity Growth Compy Commingled Pl S | 2.22M (4.67%) | 12.22K Increased by +0.55% | Sep 30, 24 |
| 3 | Fidelity Growth Compy Commingled Pl O | 2.21M (4.64%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 4 | T. Rowe Price Small-Cap Stock | 2.02M (4.26%) | 248.30K Increased by +12.27% | Mar 31, 26 |
| 5 | T. Rowe Price U.S. SC Value Eq Tr-D | 1.84M (3.87%) | 1.34M Increased by +72.56% | Mar 31, 26 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 1.59M (3.35%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Fidelity Advisor® Biotechnology I | 1.46M (3.08%) | -25.97K Decreased by -1.77% | Nov 30, 23 |
| 8 | Fidelity® Growth Company | 1.40M (2.94%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 9 | Fidelity Advisor Biotechnology I | 1.32M (2.77%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Vanguard US Total Market Shares ETF | 1.31M (2.77%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | Fidelity Growth Company Fund | 1.28M (2.69%) | -2.72K Decreased by -0.21% | Sep 30, 24 |
| 12 | abrdn Life Sciences Investors | 1.16M (2.44%) | 464.12K Increased by +40.03% | Mar 31, 26 |
| 13 | T. Rowe Price Instl Small-Cap Stock | 1.11M (2.33%) | 134.33K Increased by +12.11% | Mar 31, 26 |
| 14 | Franklin Biotechnology Discv A(acc)USD | 1.06M (2.24%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | T. Rowe Price U.S. SC Core Eq Tr-D | 947.86K (1.99%) | 947.86K Increased by +100.00% | Mar 31, 26 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 630.36K (1.33%) | 23.58K Increased by +3.74% | Mar 31, 26 |
| 17 | Fidelity Series Small Cap Opps | 622.74K (1.31%) | 18.06K Increased by +2.90% | Aug 31, 24 |
| 18 | Fidelity® Growth Company K6 | 617.99K (1.30%) | -11.77K Decreased by -1.90% | Nov 30, 23 |
| 19 | Fidelity Growth Company K6 | 550.52K (1.16%) | -9.50K Decreased by -1.73% | Sep 30, 24 |
| 20 | Franklin Biotechnology Discovery A | 505.80K (1.06%) | 0.00 Increased by 0.00% | Sep 30, 24 |