| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 5.86M (15.40%) | -25.07K Decreased by -0.43% | Mar 31, 25 |
| 2 | RTW INVESTMENTS, LLC | 5.12M (13.46%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Baker Bros Advisors LP | 4.63M (12.17%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Redmile Group, LLC | 4.49M (11.78%) | -107.65K Decreased by -2.40% | Mar 31, 25 |
| 5 | Morgan Stanley - Brokerage Accounts | 3.59M (9.43%) | 153.58K Increased by +4.28% | Mar 31, 25 |
| 6 | Skorpios Trust | 3.26M (8.55%) | -3.65M Decreased by -112.09% | Jun 30, 25 |
| 7 | COWEN AND COMPANY, LLC | 3.24M (8.52%) | -121.25K Decreased by -3.74% | Sep 30, 24 |
| 8 | The Toronto-Dominion Bank | 3.17M (8.33%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Vanguard Group Inc | 2.78M (7.31%) | 53.00K Increased by +1.90% | Mar 31, 25 |
| 10 | FMR Inc | 2.54M (6.68%) | 2.38M Increased by +93.50% | Mar 31, 25 |
| 11 | Siren, L.L.C. | 2.25M (5.90%) | 247.35K Increased by +11.01% | Mar 31, 25 |
| 12 | Marshall Wace Asset Management Ltd | 2.13M (5.60%) | 1.18M Increased by +55.37% | Mar 31, 25 |
| 13 | Logos Global Management LP | 2.10M (5.52%) | 2.10M Increased by +100.00% | Jun 30, 24 |
| 14 | Goldman Sachs Group Inc | 1.66M (4.37%) | 293.07K Increased by +17.63% | Mar 31, 25 |
| 15 | State Street Corp | 1.58M (4.14%) | -12.38K Decreased by -0.79% | Mar 31, 25 |
| 16 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.39M (3.64%) | 1.12M Increased by +80.99% | Jun 30, 24 |
| 17 | Franklin Resources Inc | 1.22M (3.19%) | 157.90K Increased by +12.98% | Jun 30, 24 |
| 18 | Geode Capital Management, LLC | 901.99K (2.37%) | 24.89K Increased by +2.76% | Mar 31, 25 |
| 19 | Checkpoint Capital LP | 730.72K (1.92%) | 425.33K Increased by +58.21% | Mar 31, 25 |
| 20 | MPM Oncology Impact Management LP | 693.99K (1.82%) | 8.16K Increased by +1.18% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 1.61M (4.22%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.57M (4.13%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Fidelity Select Biotechnology | 1.24M (3.24%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | Fidelity Select Health Care | 1.00M (2.63%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Fidelity Stock Selector Small Cap | 972.10K (2.55%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | iShares Russell 2000 ETF | 970.93K (2.55%) | -18.48K Decreased by -1.90% | Jul 31, 25 |
| 7 | BlackRock Health Sciences Opps Inv A | 925.94K (2.43%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | Polar Capital Biotech S Inc | 883.65K (2.32%) | 883.65K Increased by +100.00% | Jun 30, 25 |
| 9 | BGF World Healthscience A2 | 851.11K (2.24%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 10 | BGF World Healthscience A2 USD | 851.11K (2.24%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 11 | Fidelity Series Small Cap Opps | 836.30K (2.20%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Fidelity Advisor Biotechnology I | 711.70K (1.87%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | SPDR® S&P Biotech ETF | 626.96K (1.65%) | 18.76K Increased by +2.99% | Jul 31, 25 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 622.73K (1.64%) | 2.69K Increased by +0.43% | Jun 30, 25 |
| 15 | Fidelity Advisor Health Care I | 600.00K (1.58%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | BlackRock Health Sciences Term Trust | 530.09K (1.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | HBM Healthcare Investments AG Ord | 495.85K (1.30%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 18 | M&G (ACS) Granahan US Sm Cp Gr GBPZ1AAcc | 414.93K (1.09%) | 14.31K Increased by +3.45% | Jan 31, 24 |
| 19 | Fidelity Small Cap Index | 366.29K (0.96%) | -1.79K Decreased by -0.49% | May 31, 25 |
| 20 | iShares Russell 2000 Growth ETF | 356.62K (0.94%) | 0.00 Increased by 0.00% | Jul 31, 25 |