| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 5.62M (12.03%) | 76.67K Increased by +1.36% | Mar 31, 26 |
| 2 | FMR Inc | 5.60M (11.98%) | -1.26M Decreased by -22.57% | Dec 31, 25 |
| 3 | BlackRock Inc | 5.21M (11.15%) | -774.89K Decreased by -14.87% | Dec 31, 25 |
| 4 | Lynx1 Capital Management, LP | 4.76M (10.19%) | -641.00K Decreased by -13.46% | Mar 31, 26 |
| 5 | Redmile Group, LLC | 4.16M (8.91%) | 130.05K Increased by +3.12% | Mar 31, 26 |
| 6 | Morgan Stanley - Brokerage Accounts | 3.55M (7.58%) | 9.11K Increased by +0.26% | Dec 31, 25 |
| 7 | Baker Bros Advisors LP | 3.34M (7.14%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | COWEN AND COMPANY, LLC | 3.24M (6.94%) | -121.25K Decreased by -3.74% | Sep 30, 24 |
| 9 | The Toronto-Dominion Bank | 3.17M (6.79%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Vanguard Group Inc | 3.15M (6.74%) | -14.63K Decreased by -0.46% | Dec 31, 25 |
| 11 | State Street Corp | 2.50M (5.34%) | 1.07M Increased by +42.92% | Dec 31, 25 |
| 12 | Marshall Wace Asset Management Ltd | 2.30M (4.92%) | 168.77K Increased by +7.34% | Jun 30, 25 |
| 13 | Bvf Inc | 2.27M (4.85%) | 608.58K Increased by +26.86% | Dec 31, 25 |
| 14 | Skorpios Trust | 2.26M (4.83%) | -1.00M Decreased by -44.32% | Sep 30, 25 |
| 15 | Siren, L.L.C. | 2.25M (4.81%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 16 | Logos Global Management LP | 2.10M (4.49%) | 2.10M Increased by +100.00% | Jun 30, 24 |
| 17 | Deerfield Management Co | 1.82M (3.90%) | 1.82M Increased by +100.00% | Dec 31, 25 |
| 18 | HHG PLC | 1.45M (3.10%) | 1.12M Increased by +76.95% | Dec 31, 25 |
| 19 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.39M (2.97%) | 1.12M Increased by +80.99% | Jun 30, 24 |
| 20 | Goldman Sachs Group Inc | 1.30M (2.78%) | -360.66K Decreased by -27.71% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.72M (3.69%) | 11.88K Increased by +0.69% | Mar 31, 26 |
| 2 | Vanguard Health Care Inv | 1.65M (3.53%) | 1.65M Increased by +100.00% | Mar 31, 26 |
| 3 | Vanguard US Total Market Shares ETF | 1.61M (3.44%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 1.24M (2.66%) | -8.93K Decreased by -0.72% | Apr 30, 26 |
| 5 | Fidelity Select Biotechnology | 1.21M (2.58%) | 413.80K Increased by +34.30% | Mar 31, 26 |
| 6 | iShares Russell 2000 ETF | 1.16M (2.47%) | 9.73K Increased by +0.84% | Apr 30, 26 |
| 7 | Polar Capital Biotech S Inc | 1.07M (2.29%) | -114.55K Decreased by -10.69% | Mar 31, 26 |
| 8 | BGF World Healthscience A2 USD | 851.11K (1.82%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 9 | Fidelity Select Health Care | 680.00K (1.45%) | -70.00K Decreased by -10.29% | Mar 31, 26 |
| 10 | SPDR® S&P Biotech ETF | 626.96K (1.34%) | 1.40K Increased by +0.22% | Aug 31, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 574.53K (1.23%) | 14.82K Increased by +2.58% | Mar 31, 26 |
| 12 | Fidelity Stock Selector Small Cap | 562.90K (1.20%) | 30.00K Increased by +5.33% | Feb 28, 26 |
| 13 | Fidelity Small Cap Growth | 520.83K (1.11%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 14 | FIAM Small Cap Core Composite | 511.40K (1.09%) | -41.90K Decreased by -8.19% | Dec 31, 25 |
| 15 | HBM Healthcare Investments AG Ord | 495.85K (1.06%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 16 | T. Rowe Price New Horizons | 483.24K (1.03%) | 296.37K Increased by +61.33% | Mar 31, 26 |
| 17 | US Small-Cap Growth II Equity Comp | 483.24K (1.03%) | 483.24K Increased by +100.00% | Mar 31, 26 |
| 18 | BlackRock Health Sciences Opps Inv A | 473.15K (1.01%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 19 | RTW Biotech Opportunities Ord | 457.19K (0.98%) | 457.19K Increased by +100.00% | Jun 30, 25 |
| 20 | FIAM Small Cap Core CIT Cl B | 445.00K (0.95%) | 0.00 Increased by 0.00% | Feb 28, 26 |