| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 5.14M (12.47%) | -47.37K Decreased by -0.92% | Mar 31, 25 |
| 2 | Vivo Capital, LLC | 4.46M (10.81%) | -1.83M Decreased by -41.13% | Mar 31, 25 |
| 3 | Adage Capital Partners Gp LLC | 4.39M (10.65%) | 1.62M Increased by +36.80% | Mar 31, 25 |
| 4 | venBio Select Advisor LLC | 2.52M (6.12%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | T. Rowe Price Associates, Inc. | 2.40M (5.82%) | 769.70K Increased by +32.07% | Mar 31, 25 |
| 6 | FMR Inc | 2.23M (5.42%) | 1.42M Increased by +63.60% | Mar 31, 25 |
| 7 | BlackRock Inc | 1.91M (4.64%) | -96.46K Decreased by -5.04% | Mar 31, 25 |
| 8 | Vanguard Group Inc | 1.87M (4.53%) | -18.21K Decreased by -0.98% | Mar 31, 25 |
| 9 | Nantahala Capital Management, LLC | 1.76M (4.26%) | -2.17M Decreased by -123.61% | Mar 31, 25 |
| 10 | Citadel Advisors Llc | 1.58M (3.82%) | 603.63K Increased by +38.30% | Mar 31, 25 |
| 11 | Perceptive Advisors LLC | 1.51M (3.65%) | 5.56K Increased by +0.37% | Mar 31, 25 |
| 12 | RA Capital Management, LLC | 1.24M (3.01%) | 1.24M Increased by +100.00% | Sep 30, 23 |
| 13 | Westfield Capital Management Company, L.P. | 1.21M (2.94%) | 329.79K Increased by +27.23% | Mar 31, 25 |
| 14 | Holocene Advisors, LP | 1.20M (2.90%) | 241.52K Increased by +20.18% | Mar 31, 25 |
| 15 | State Street Corp | 1.17M (2.84%) | -177.82K Decreased by -15.21% | Mar 31, 25 |
| 16 | COMMODORE CAPITAL LP | 1.15M (2.79%) | -375.00K Decreased by -32.61% | Mar 31, 25 |
| 17 | Fairmount Funds Management LLC | 1.14M (2.77%) | 1.14M Increased by +100.00% | Sep 30, 23 |
| 18 | Vestal Point Capital LP | 1.06M (2.57%) | 340.00K Increased by +32.08% | Dec 31, 24 |
| 19 | Alyeska Investment Group, L.P. | 976.11K (2.37%) | 976.11K Increased by +100.00% | Sep 30, 24 |
| 20 | State Street Corporation | 970.57K (2.35%) | 469.17K Increased by +48.34% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.48M (3.58%) | 339.77K Increased by +23.01% | Jun 30, 25 |
| 2 | T. Rowe Price All-Cap Opportunities Fund | 1.12M (2.72%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | T. Rowe Price US All-Cap Opp Eq Comp | 1.12M (2.72%) | 390.37K Increased by +34.76% | Jun 30, 25 |
| 4 | iShares Russell 2000 ETF | 965.12K (2.34%) | -15.56K Decreased by -1.61% | Jul 30, 25 |
| 5 | Janus Henderson Global Life Sciences D | 919.83K (2.23%) | -5.22K Decreased by -0.57% | May 31, 25 |
| 6 | Vanguard US Total Market Shares ETF | 913.59K (2.22%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Janus Henderson Global Life Sciences | 905.88K (2.20%) | -17.78K Decreased by -1.96% | Jun 30, 25 |
| 8 | Polar Capital Biotech S Inc | 817.50K (1.98%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Janus Global Life Science AUSD | 749.01K (1.82%) | 10.14K Increased by +1.35% | Mar 31, 25 |
| 10 | Janus Henderson Glb Life Scn I2 USD | 747.16K (1.81%) | 3.65K Increased by +0.49% | Jun 30, 25 |
| 11 | American Funds SMALLCAP World A | 614.83K (1.49%) | 150.00K Increased by +24.40% | Jun 30, 25 |
| 12 | T. Rowe Price Health Sciences | 586.46K (1.42%) | -10.99K Decreased by -1.87% | Jun 30, 25 |
| 13 | SPDR® S&P Biotech ETF | 575.48K (1.40%) | 14.19K Increased by +2.47% | Jul 31, 25 |
| 14 | T. Rowe Price New Horizons | 539.98K (1.31%) | 114.59K Increased by +21.22% | Jun 30, 25 |
| 15 | US Small-Cap Growth II Equity Comp | 539.98K (1.31%) | 132.83K Increased by +24.60% | Jun 30, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 522.36K (1.27%) | 113.28K Increased by +21.69% | Jun 30, 25 |
| 17 | Fidelity Select Health Care | 520.00K (1.26%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Janus Henderson Triton D | 450.38K (1.09%) | 0.00 Increased by 0.00% | May 31, 25 |
| 19 | Janus Henderson US SMID Cap Growth | 445.13K (1.08%) | -5.25K Decreased by -1.18% | Jun 30, 25 |
| 20 | Janus Henderson US SMID Cap Growth MA | 445.13K (1.08%) | 445.10K Increased by +99.99% | Jun 30, 25 |