Price
$23.07
Decreased by -0.30%
Dollar volume (20D)
6.22 M
ADR%
6.32
Earnings report date
Nov 19, 2025
Shares float
18.18 M
Shares short
3.07 M [16.91%]
Shares outstanding
44.59 M
Market cap
1.03 B
Beta
N/A
Price/earnings
N/A
20D range
14.00 23.61
50D range
10.62 23.61
200D range
4.17 28.99

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases.

It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves' disease and thyroid eye disease.

The company also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders, including obesity and type 2 diabetes.

In addition, it focuses on other therapeutic areas, including neurology, women's health, cardiovascular disease, and respiratory disease.

The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021.

Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

Reported date EPSChange YoY EstimateSurprise
Aug 11, 25 -0.56
Increased by +95.61%
-0.63
Increased by +11.11%
May 15, 25 -0.49 -0.54
Increased by +9.26%
Mar 27, 25 -0.64 -0.69
Increased by +6.80%
Nov 20, 24 -4.62 -
Aug 28, 24 -12.76 -
Fiscal ending date RevenueChange YoY IncomeChange YoY ProfitChange YoY
Jun 30, 25 119.00 K
Decreased by -67.84%
-24.84 M
Decreased by -51.07%
Decreased by -20.87 K%
Decreased by -369.72%
Mar 31, 25 219.00 K
Decreased by -30.91%
-21.48 M
Decreased by -51.60%
Decreased by -9.81 K%
Decreased by -119.44%
Dec 31, 24 212.00 K
Increased by +79.66%
-20.67 M
Decreased by -159.23%
Decreased by -9.75 K%
Decreased by -132.97%
Sep 30, 24 176.00 K
Increased by +433.33%
-20.52 M
Decreased by -87.51%
Decreased by -11.66 K%
Increased by +64.84%
Jun 30, 24 370.00 K - -16.44 M -
Decreased by -4.44 K%
-
Mar 31, 24 317.00 K - -14.17 M -
Decreased by -4.47 K%
-
Dec 31, 23 118.00 K - 34.89 M -
Increased by +29.57 K%
-
Sep 30, 23 33.00 K - -10.95 M -
Decreased by -33.17 K%
-
Open dropdown content
Open dropdown content
DAILY
WEEKLY
MONTHLY