| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Wellington Management Company LLP | 4.75M (9.26%) | -1.31M Decreased by -27.56% | Mar 31, 24 |
| 2 | BlackRock Inc | 4.66M (9.08%) | -189.65K Decreased by -4.07% | Mar 31, 25 |
| 3 | State Street Corporation | 4.49M (8.76%) | 576.57K Increased by +12.83% | Mar 31, 24 |
| 4 | Madison Avenue Partners, LP | 4.48M (8.73%) | 4.48M Increased by +100.00% | Mar 31, 25 |
| 5 | Bellevue Group AG | 4.46M (8.69%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | FMR Inc | 4.12M (8.02%) | -1.15M Decreased by -28.03% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 3.27M (6.36%) | -1.81M Decreased by -55.47% | Jun 30, 25 |
| 8 | Caligan Partners LP | 3.05M (5.95%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | RTW INVESTMENTS, LLC | 3.00M (5.85%) | -2.59M Decreased by -86.24% | Dec 31, 24 |
| 10 | Test Hedge Fund Mgmt | 2.73M (5.32%) | 2.73M Increased by +100.00% | Mar 31, 25 |
| 11 | Deep Track Capital, LP | 2.04M (3.97%) | 2.04M Increased by +100.00% | Mar 31, 25 |
| 12 | D. E. Shaw & Co LP | 1.92M (3.74%) | -170.16K Decreased by -8.88% | Jun 30, 25 |
| 13 | Marshall Wace Asset Management Ltd | 1.76M (3.43%) | 1.76M Increased by +100.00% | Mar 31, 25 |
| 14 | Millennium Management LLC | 1.62M (3.16%) | 124.72K Increased by +7.68% | Dec 31, 24 |
| 15 | Morgan Stanley - Brokerage Accounts | 1.40M (2.73%) | -3.20M Decreased by -228.41% | Mar 31, 25 |
| 16 | BOOTHBAY FUND MANAGEMENT, LLC | 1.38M (2.70%) | -4.04K Decreased by -0.29% | Mar 31, 25 |
| 17 | COWEN AND COMPANY, LLC | 1.34M (2.61%) | 1.34M Increased by +100.00% | Dec 31, 23 |
| 18 | Geode Capital Management, LLC | 1.30M (2.54%) | 46.47K Increased by +3.57% | Mar 31, 25 |
| 19 | Eckert Corp | 1.27M (2.48%) | 1.27M Increased by +100.00% | Jun 30, 25 |
| 20 | JPMorgan Chase & Co | 1.20M (2.34%) | 45.26K Increased by +3.77% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 4.46M (8.69%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Health Care Inv | 4.30M (8.39%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 3 | Fidelity Growth Compy Commingled Pl O | 2.39M (4.66%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.82M (3.55%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Fidelity® Growth Company | 1.81M (3.52%) | -212.30K Decreased by -11.76% | Nov 30, 23 |
| 6 | Vanguard US Total Market Shares ETF | 1.71M (3.34%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | SPDR® S&P Biotech ETF | 1.63M (3.17%) | 23.14K Increased by +1.42% | Nov 30, 24 |
| 8 | iShares Russell 2000 ETF | 1.42M (2.77%) | 9.88K Increased by +0.69% | Jun 30, 25 |
| 9 | Vanguard Strategic Equity Inv | 1.07M (2.09%) | 412.85K Increased by +38.52% | Mar 31, 25 |
| 10 | DWS Vermögensbildungsfonds I LD | 1.00M (1.95%) | 2.00 Increased by +0.00% | May 31, 24 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 861.90K (1.68%) | -19.18K Decreased by -2.22% | Jun 30, 25 |
| 12 | Fidelity Growth Compy Commingled Pl S | 756.86K (1.47%) | -1.27M Decreased by -167.24% | Jan 31, 25 |
| 13 | Merchfondo FI | 746.50K (1.45%) | -233.50K Decreased by -31.28% | Mar 31, 25 |
| 14 | Vanguard Small Cap Index | 694.00K (1.35%) | 4.05K Increased by +0.58% | Nov 30, 24 |
| 15 | Fidelity® Growth Company K6 | 635.97K (1.24%) | -149.66K Decreased by -23.53% | Nov 30, 23 |
| 16 | Fidelity® Select Biotechnology | 579.85K (1.13%) | -73.20K Decreased by -12.62% | Nov 30, 23 |
| 17 | Invesco Biotechnology & Genome ETF | 574.37K (1.12%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | Fidelity Small Cap Index | 549.75K (1.07%) | -4.35K Decreased by -0.79% | May 31, 25 |
| 19 | JPMorgan Small Cap Growth A | 548.54K (1.07%) | -11.50K Decreased by -2.10% | May 31, 24 |
| 20 | T. Rowe Price Health Sciences | 535.36K (1.04%) | 229.71K Increased by +42.91% | Mar 31, 24 |