| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 4.85M (9.85%) | -540.20K Decreased by -11.14% | Dec 31, 24 |
| 2 | Vanguard Group Inc | 4.84M (9.82%) | -922.28K Decreased by -19.06% | Dec 31, 24 |
| 3 | Wellington Management Company LLP | 4.75M (9.65%) | -1.31M Decreased by -27.56% | Mar 31, 24 |
| 4 | Morgan Stanley - Brokerage Accounts | 4.59M (9.33%) | 3.79M Increased by +82.40% | Dec 31, 24 |
| 5 | State Street Corporation | 4.49M (9.12%) | 576.57K Increased by +12.83% | Mar 31, 24 |
| 6 | Bellevue Group AG | 4.46M (9.05%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | FMR Inc | 4.12M (8.36%) | -1.15M Decreased by -28.03% | Dec 31, 24 |
| 8 | Caligan Partners LP | 3.05M (6.20%) | 3.05M Increased by +100.00% | Dec 31, 24 |
| 9 | RTW INVESTMENTS, LLC | 3.00M (6.09%) | -2.59M Decreased by -86.24% | Dec 31, 24 |
| 10 | Millennium Management LLC | 1.62M (3.30%) | 124.72K Increased by +7.68% | Dec 31, 24 |
| 11 | BOOTHBAY FUND MANAGEMENT, LLC | 1.39M (2.82%) | 1.39M Increased by +100.00% | Dec 31, 24 |
| 12 | COWEN AND COMPANY, LLC | 1.34M (2.72%) | 1.34M Increased by +100.00% | Dec 31, 23 |
| 13 | State Street Corp | 1.27M (2.58%) | -1.65M Decreased by -129.93% | Dec 31, 24 |
| 14 | Geode Capital Management, LLC | 1.26M (2.55%) | 14.05K Increased by +1.12% | Dec 31, 24 |
| 15 | JPMorgan Chase & Co | 1.20M (2.44%) | 45.26K Increased by +3.77% | Jun 30, 24 |
| 16 | Jacobs Levy Equity Management, Inc. | 1.12M (2.28%) | -136.71K Decreased by -12.17% | Dec 31, 24 |
| 17 | Federated Hermes Inc | 1.11M (2.24%) | 430.43K Increased by +38.93% | Dec 31, 24 |
| 18 | Boxer Capital LLC | 1.09M (2.22%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | Deutsche Bank AG | 1.03M (2.09%) | 2.74K Increased by +0.27% | Mar 31, 24 |
| 20 | Palo Alto Investors, LLC | 1.01M (2.05%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 4.46M (9.05%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Health Care Inv | 4.30M (8.74%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 3 | Fidelity Growth Compy Commingled Pl O | 2.39M (4.85%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 4 | Fidelity® Growth Company | 1.81M (3.66%) | -212.30K Decreased by -11.76% | Nov 30, 23 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.71M (3.47%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 6 | SPDR® S&P Biotech ETF | 1.63M (3.30%) | 23.14K Increased by +1.42% | Nov 30, 24 |
| 7 | iShares Russell 2000 ETF | 1.45M (2.95%) | 6.21K Increased by +0.43% | Mar 31, 25 |
| 8 | DWS Vermögensbildungsfonds I LD | 1.00M (2.03%) | 2.00 Increased by +0.00% | May 31, 24 |
| 9 | Merchfondo FI | 980.00K (1.99%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 872.05K (1.77%) | 1.52K Increased by +0.17% | Feb 28, 25 |
| 11 | Federated Hermes MDT SCC Institutional | 769.44K (1.56%) | 386.23K Increased by +50.20% | Dec 31, 24 |
| 12 | Federated Hermes MDT Small Cap Core IS | 769.44K (1.56%) | 386.23K Increased by +50.20% | Dec 31, 24 |
| 13 | Fidelity Growth Compy Commingled Pl S | 756.86K (1.54%) | -1.27M Decreased by -167.24% | Jan 31, 25 |
| 14 | Vanguard Small Cap Index | 694.00K (1.41%) | 4.05K Increased by +0.58% | Nov 30, 24 |
| 15 | Vanguard Strategic Equity Inv | 659.02K (1.34%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 16 | Fidelity® Growth Company K6 | 635.97K (1.29%) | -149.66K Decreased by -23.53% | Nov 30, 23 |
| 17 | Fidelity® Select Biotechnology | 579.85K (1.18%) | -73.20K Decreased by -12.62% | Nov 30, 23 |
| 18 | Invesco Biotechnology & Genome ETF | 574.37K (1.17%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 19 | JPMorgan Small Cap Growth A | 548.54K (1.11%) | -11.50K Decreased by -2.10% | May 31, 24 |
| 20 | Fidelity Small Cap Index | 547.63K (1.11%) | -10.26K Decreased by -1.87% | Jan 31, 25 |