| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Inc | 14.03M (21.42%) | 2.76M Increased by +19.63% | Jun 30, 25 |
| 2 | FMR Inc | 12.81M (19.55%) | 6.30M Increased by +49.21% | Jun 30, 25 |
| 3 | BlackRock Inc | 4.08M (6.23%) | 3.63M Increased by +89.04% | Jun 30, 25 |
| 4 | Vanguard Group Inc | 4.02M (6.14%) | 1.65M Increased by +40.95% | Jun 30, 25 |
| 5 | Blackstone Inc | 3.56M (5.43%) | 1.82M Increased by +50.99% | Jun 30, 25 |
| 6 | UBS Group AG | 3.04M (4.63%) | 2.42M Increased by +79.70% | Jun 30, 25 |
| 7 | Great Point Partners LLC | 3.03M (4.63%) | 2.20M Increased by +72.54% | Jun 30, 25 |
| 8 | Marshall Wace Asset Management Ltd | 2.89M (4.40%) | 1.04M Increased by +36.07% | Jun 30, 25 |
| 9 | Stonepine Capital Management Llc | 2.77M (4.22%) | -303.82K Decreased by -10.97% | Dec 31, 23 |
| 10 | First Manhattan Co. LLC | 2.68M (4.09%) | -942.10K Decreased by -35.14% | Dec 31, 23 |
| 11 | Adage Capital Partners Gp LLC | 2.53M (3.85%) | 2.21M Increased by +87.50% | Dec 31, 24 |
| 12 | Mangrove Partners | 2.30M (3.51%) | 2.30M Increased by +100.00% | Jun 30, 25 |
| 13 | Nantahala Capital Management, LLC | 2.29M (3.50%) | 1.00M Increased by +43.64% | Jun 30, 25 |
| 14 | Affinity Asset Advisors, LLC | 2.20M (3.36%) | 500.00K Increased by +22.73% | Jun 30, 25 |
| 15 | Vivo Capital, LLC | 2.11M (3.22%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | Woodline Partners LP | 1.90M (2.91%) | 875.92K Increased by +46.00% | Jun 30, 25 |
| 17 | Integral Health Asset Management, LLC | 1.80M (2.75%) | 1.30M Increased by +72.22% | Jun 30, 25 |
| 18 | Rosalind Advisors, Inc. | 1.74M (2.66%) | 1.74M Increased by +100.00% | Jun 30, 25 |
| 19 | Geode Capital Management, LLC | 1.71M (2.61%) | 1.14M Increased by +66.85% | Jun 30, 25 |
| 20 | Altium Capital Management, LP | 1.69M (2.58%) | -6.00K Decreased by -0.35% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Kaufmann R | 6.99M (10.66%) | 2.15M Increased by +30.82% | Jun 30, 25 |
| 2 | Federated Hermes Kaufmann Growth | 5.98M (9.12%) | 2.15M Increased by +36.03% | Jun 30, 25 |
| 3 | Federated Hermes Kaufmann Small Cap A | 5.19M (7.91%) | 533.00K Increased by +10.28% | Jun 30, 25 |
| 4 | Federated Hermes Kaufmann Small Cap Grow | 4.35M (6.63%) | 533.00K Increased by +12.26% | Jun 30, 25 |
| 5 | Fidelity Select Health Care | 2.80M (4.27%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Fidelity Advisor Biotechnology I | 2.75M (4.19%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 7 | Vanguard Total Stock Mkt Idx Inv | 2.23M (3.40%) | -49.47K Decreased by -2.22% | Jul 31, 25 |
| 8 | Fidelity Stock Selector Small Cap | 2.17M (3.31%) | 560.60K Increased by +25.85% | Jun 30, 25 |
| 9 | Fidelity Series Small Cap Opps | 1.91M (2.92%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | iShares Russell 2000 ETF | 1.61M (2.46%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 11 | Fidelity Advisor Health Care I | 1.60M (2.44%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | Vanguard US Total Market Shares ETF | 1.08M (1.65%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 786.87K (1.20%) | -368.37K Decreased by -46.81% | Jul 31, 25 |
| 14 | Fidelity Small Cap Index | 671.29K (1.02%) | 671.29K Increased by +100.00% | Jun 30, 25 |
| 15 | Fidelity Select Biotechnology | 631.08K (0.96%) | -9.70K Decreased by -1.54% | Jul 31, 25 |
| 16 | MEDICAL BioHealth EUR Acc | 611.07K (0.93%) | 199.07K Increased by +32.58% | Jun 30, 25 |
| 17 | iShares Russell 2000 Growth ETF | 519.04K (0.79%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 18 | Fidelity VIP Health Care Initial | 450.00K (0.69%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Fidelity Extended Market Index | 381.57K (0.58%) | -3.14K Decreased by -0.82% | Jul 31, 25 |
| 20 | Vanguard Russell 2000 ETF | 319.38K (0.49%) | -21.37K Decreased by -6.69% | Jul 31, 25 |