| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Inc | 12.99M (19.67%) | -3.54M Decreased by -27.28% | Mar 31, 26 |
| 2 | RA Capital Management, LLC | 9.18M (13.90%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | BlackRock Inc | 6.31M (9.56%) | -454.70K Decreased by -7.20% | Mar 31, 26 |
| 4 | Opaleye Management Inc | 6.30M (9.54%) | 12.84K Increased by +0.20% | Mar 31, 26 |
| 5 | Balyasny Asset Management LLC | 5.05M (7.65%) | 541.56K Increased by +10.73% | Mar 31, 26 |
| 6 | Vanguard Group Inc | 4.79M (7.25%) | 378.43K Increased by +7.90% | Dec 31, 25 |
| 7 | Vanguard Capital Management, LLC | 3.52M (5.33%) | 3.52M Increased by +100.00% | Mar 31, 26 |
| 8 | Jennison Associates LLC | 3.44M (5.21%) | 3.44M Increased by +100.00% | Mar 31, 26 |
| 9 | Siren, L.L.C. | 3.33M (5.04%) | 3.33M Increased by +100.00% | Mar 31, 26 |
| 10 | Blackstone Inc | 3.02M (4.58%) | -536.39K Decreased by -17.74% | Sep 30, 25 |
| 11 | Vanguard Portfolio Management, LLC | 2.98M (4.52%) | 2.98M Increased by +100.00% | Mar 31, 26 |
| 12 | Bank of America Corp | 2.97M (4.50%) | -1.35M Decreased by -45.60% | Mar 31, 26 |
| 13 | Mangrove Partners | 2.88M (4.36%) | 584.66K Increased by +20.29% | Sep 30, 25 |
| 14 | Stonepine Capital Management Llc | 2.77M (4.19%) | -303.82K Decreased by -10.97% | Dec 31, 23 |
| 15 | Morgan Stanley - Brokerage Accounts | 2.75M (4.16%) | 1.23M Increased by +44.81% | Mar 31, 26 |
| 16 | Marshall Wace Asset Management Ltd | 2.73M (4.13%) | -158.17K Decreased by -5.80% | Sep 30, 25 |
| 17 | First Manhattan Co. LLC | 2.68M (4.06%) | -942.10K Decreased by -35.14% | Dec 31, 23 |
| 18 | Adage Capital Partners Gp LLC | 2.53M (3.83%) | 2.21M Increased by +87.50% | Dec 31, 24 |
| 19 | FMR Inc | 2.31M (3.49%) | -10.46M Decreased by -453.63% | Dec 31, 25 |
| 20 | Nantahala Capital Management, LLC | 2.29M (3.47%) | 1.00M Increased by +43.64% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Kaufmann R | 8.49M (12.86%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Federated Hermes Kaufmann Growth | 7.48M (11.33%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Federated Hermes Kaufmann Small Cap A | 6.18M (9.36%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Federated Hermes Kaufmann Small Cap Grow | 5.34M (8.09%) | 585.86K Increased by +10.97% | Mar 31, 26 |
| 5 | Fidelity Select Health Care | 2.80M (4.24%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 2.48M (3.75%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 7 | State Street® SPDR® S&P® Biotech ETF | 2.32M (3.51%) | 12.87K Increased by +0.55% | Feb 28, 26 |
| 8 | Fidelity Advisor Biotechnology I | 1.99M (3.01%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 9 | Fidelity Stock Selector Small Cap | 1.91M (2.90%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 10 | iShares Russell 2000 ETF | 1.74M (2.64%) | 16.07K Increased by +0.92% | May 29, 26 |
| 11 | Fidelity Series Small Cap Opps | 1.65M (2.50%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 12 | Fidelity Advisor Health Care I | 1.60M (2.42%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 13 | Fidelity Small Cap Growth | 1.34M (2.04%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 14 | Vanguard US Total Market Shares ETF | 1.08M (1.64%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Vanguard Strategic Small-Cap Equity Inv | 986.45K (1.49%) | 728.70K Increased by +73.87% | Mar 31, 26 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 965.50K (1.46%) | 164.00 Increased by +0.02% | Apr 30, 26 |
| 17 | Vanguard Explorer Inv | 741.50K (1.12%) | 741.50K Increased by +100.00% | Mar 31, 26 |
| 18 | Kennedy Micro Cap | 738.25K (1.12%) | 373.30K Increased by +50.57% | Mar 31, 26 |
| 19 | Fidelity Small Cap Index | 713.57K (1.08%) | -77.21K Decreased by -10.82% | Mar 31, 26 |
| 20 | Fidelity Small Cap Growth K6 | 676.67K (1.02%) | 0.00 Increased by 0.00% | Nov 30, 25 |