| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 16.61M (9.85%) | -484.42K Decreased by -2.92% | Mar 31, 25 |
| 2 | BlackRock Inc | 14.69M (8.71%) | -27.16K Decreased by -0.18% | Mar 31, 25 |
| 3 | Farallon Capital Management, L.L.C. | 13.53M (8.02%) | 286.00K Increased by +2.11% | Mar 31, 25 |
| 4 | Wellington Management Company LLP | 11.79M (6.99%) | 966.23K Increased by +8.20% | Mar 31, 25 |
| 5 | HHG PLC | 10.19M (6.04%) | 706.07K Increased by +6.93% | Mar 31, 25 |
| 6 | Baker Bros Advisors LP | 7.94M (4.70%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Nextech Invest AG | 7.60M (4.50%) | 1.30M Increased by +17.16% | Dec 31, 24 |
| 8 | Nextech Invest, Ltd. | 7.60M (4.50%) | 7.60M Increased by +100.00% | Mar 31, 25 |
| 9 | FMR Inc | 7.54M (4.47%) | 793.69K Increased by +10.53% | Mar 31, 25 |
| 10 | Paradigm Biocapital Advisors LP | 6.18M (3.66%) | -375.00K Decreased by -6.07% | Mar 31, 25 |
| 11 | State Street Corp | 5.80M (3.44%) | 13.17K Increased by +0.23% | Mar 31, 25 |
| 12 | T. Rowe Price Associates, Inc. | 5.60M (3.32%) | -266.32K Decreased by -4.76% | Mar 31, 25 |
| 13 | EcoR1 Capital, LLC | 5.58M (3.31%) | -1.62M Decreased by -29.06% | Sep 30, 23 |
| 14 | State Street Corporation | 5.39M (3.19%) | -867.34K Decreased by -16.10% | Mar 31, 24 |
| 15 | Bvf Inc | 4.98M (2.95%) | 801.21K Increased by +16.08% | Mar 31, 25 |
| 16 | Bellevue Group AG | 4.37M (2.59%) | -12.60K Decreased by -0.29% | Mar 31, 25 |
| 17 | Boxer Capital LLC | 4.28M (2.54%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 18 | Boxer Capital Management, LLC | 4.28M (2.54%) | 4.28M Increased by +100.00% | Dec 31, 24 |
| 19 | Geode Capital Management, LLC | 4.14M (2.46%) | 56.22K Increased by +1.36% | Mar 31, 25 |
| 20 | Alphabet Inc | 4.13M (2.45%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 5.39M (3.19%) | 20.38K Increased by +0.38% | Jun 30, 25 |
| 2 | Vanguard US Total Market Shares ETF | 4.74M (2.81%) | 4.24K Increased by +0.09% | Sep 30, 24 |
| 3 | BB Biotech AG Ord | 4.37M (2.59%) | -484.46K Decreased by -11.08% | Dec 31, 24 |
| 4 | iShares Russell 2000 ETF | 4.27M (2.53%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | Vanguard Small Cap Index | 4.09M (2.43%) | -126.15K Decreased by -3.08% | Jun 30, 25 |
| 6 | Vanguard Health Care Inv | 3.87M (2.30%) | -946.03K Decreased by -24.42% | Jun 30, 25 |
| 7 | Fidelity Growth Compy Commingled Pl S | 3.07M (1.82%) | 317.03K Increased by +10.33% | Jun 30, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 2.70M (1.60%) | -686.00 Decreased by -0.03% | Jun 30, 25 |
| 9 | Janus Henderson Enterprise D | 2.40M (1.42%) | 0.00 Increased by 0.00% | May 31, 25 |
| 10 | Janus Inst Mid Cap Growth CF | 2.40M (1.42%) | 377.18K Increased by +15.69% | Jun 30, 25 |
| 11 | Vanguard Small Cap Growth Index Inv | 2.30M (1.36%) | -25.93K Decreased by -1.13% | Jun 30, 25 |
| 12 | Fidelity Growth Company Fund | 2.25M (1.34%) | 234.80K Increased by +10.42% | Jun 30, 25 |
| 13 | SPDR® S&P Biotech ETF | 1.86M (1.10%) | 45.76K Increased by +2.46% | Jul 31, 25 |
| 14 | Fidelity Small Cap Index | 1.73M (1.02%) | 3.93K Increased by +0.23% | May 31, 25 |
| 15 | US Small-Cap Growth II Equity Comp | 1.66M (0.98%) | -539.14K Decreased by -32.51% | Jun 30, 25 |
| 16 | T. Rowe Price Mid-Cap Growth | 1.50M (0.89%) | 250.20K Increased by +16.68% | Jun 30, 25 |
| 17 | T. Rowe Price US Mid-Cap Growth Equity | 1.50M (0.89%) | 1.50M Increased by +100.00% | Jun 30, 25 |
| 18 | Fidelity Growth Compy Commingled Pl O | 1.44M (0.85%) | 16.60K Increased by +1.15% | Aug 31, 24 |
| 19 | T. Rowe Price Health Sciences | 1.38M (0.82%) | -51.79K Decreased by -3.77% | Jun 30, 25 |
| 20 | T. Rowe Price New Horizons | 1.36M (0.80%) | -242.13K Decreased by -17.86% | Jun 30, 25 |