| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 16.61M (9.88%) | -484.42K Decreased by -2.92% | Mar 31, 25 |
| 2 | BlackRock Inc | 14.69M (8.74%) | -27.16K Decreased by -0.18% | Mar 31, 25 |
| 3 | Farallon Capital Management, L.L.C. | 13.53M (8.05%) | 286.00K Increased by +2.11% | Mar 31, 25 |
| 4 | Wellington Management Company LLP | 11.79M (7.01%) | 966.23K Increased by +8.20% | Mar 31, 25 |
| 5 | HHG PLC | 10.19M (6.06%) | 706.07K Increased by +6.93% | Mar 31, 25 |
| 6 | Baker Bros Advisors LP | 7.94M (4.72%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Nextech Invest AG | 7.60M (4.52%) | 1.30M Increased by +17.16% | Dec 31, 24 |
| 8 | Nextech Invest, Ltd. | 7.60M (4.52%) | 7.60M Increased by +100.00% | Mar 31, 25 |
| 9 | FMR Inc | 7.54M (4.48%) | 793.69K Increased by +10.53% | Mar 31, 25 |
| 10 | Paradigm Biocapital Advisors LP | 6.18M (3.67%) | -375.00K Decreased by -6.07% | Mar 31, 25 |
| 11 | State Street Corp | 5.80M (3.45%) | 13.17K Increased by +0.23% | Mar 31, 25 |
| 12 | T. Rowe Price Associates, Inc. | 5.60M (3.33%) | -266.32K Decreased by -4.76% | Mar 31, 25 |
| 13 | EcoR1 Capital, LLC | 5.58M (3.32%) | -1.62M Decreased by -29.06% | Sep 30, 23 |
| 14 | State Street Corporation | 5.39M (3.20%) | -867.34K Decreased by -16.10% | Mar 31, 24 |
| 15 | Bvf Inc | 4.98M (2.96%) | 801.21K Increased by +16.08% | Mar 31, 25 |
| 16 | Bellevue Group AG | 4.37M (2.60%) | -12.60K Decreased by -0.29% | Mar 31, 25 |
| 17 | Boxer Capital LLC | 4.28M (2.54%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 18 | Boxer Capital Management, LLC | 4.28M (2.54%) | 4.28M Increased by +100.00% | Dec 31, 24 |
| 19 | Geode Capital Management, LLC | 4.14M (2.46%) | 56.22K Increased by +1.36% | Mar 31, 25 |
| 20 | Alphabet Inc | 4.13M (2.46%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 5.37M (3.19%) | 3.88K Increased by +0.07% | May 31, 25 |
| 2 | Vanguard Health Care Inv | 4.82M (2.87%) | 524.69K Increased by +10.89% | Mar 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 4.74M (2.82%) | 4.24K Increased by +0.09% | Sep 30, 24 |
| 4 | BB Biotech AG Ord | 4.37M (2.60%) | -484.46K Decreased by -11.08% | Dec 31, 24 |
| 5 | iShares Russell 2000 ETF | 4.27M (2.54%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | Vanguard Small Cap Index | 4.22M (2.51%) | 20.44K Increased by +0.48% | May 31, 25 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 2.71M (1.61%) | 22.58K Increased by +0.83% | May 31, 25 |
| 8 | Fidelity Growth Compy Commingled Pl S | 2.50M (1.49%) | 248.90K Increased by +9.96% | Apr 30, 25 |
| 9 | Janus Henderson Enterprise D | 2.40M (1.43%) | 377.18K Increased by +15.69% | Apr 30, 25 |
| 10 | Vanguard Small Cap Growth Index Inv | 2.32M (1.38%) | -13.87K Decreased by -0.60% | May 31, 25 |
| 11 | US Small-Cap Growth II Equity Comp | 2.20M (1.31%) | -26.18K Decreased by -1.19% | Mar 31, 25 |
| 12 | Janus Inst Mid Cap Growth CF | 2.03M (1.21%) | 171.50K Increased by +8.46% | Mar 31, 25 |
| 13 | T. Rowe Price New Horizons | 1.89M (1.13%) | -25.62K Decreased by -1.35% | Mar 31, 25 |
| 14 | SPDR® S&P Biotech ETF | 1.88M (1.12%) | 11.13K Increased by +0.59% | May 31, 25 |
| 15 | Fidelity Growth Company Fund | 1.80M (1.07%) | 210.50K Increased by +11.68% | Apr 30, 25 |
| 16 | Fidelity Small Cap Index | 1.70M (1.01%) | 41.13K Increased by +2.42% | Mar 31, 25 |
| 17 | T. Rowe Price Health Sciences | 1.60M (0.95%) | -124.00K Decreased by -7.73% | Mar 31, 25 |
| 18 | Fidelity Growth Compy Commingled Pl O | 1.44M (0.86%) | 16.60K Increased by +1.15% | Aug 31, 24 |
| 19 | Vanguard Explorer Inv | 1.24M (0.74%) | 191.82K Increased by +15.50% | Mar 31, 25 |
| 20 | Janus Henderson Global Life Sciences | 1.24M (0.74%) | -89.55K Decreased by -7.24% | Mar 31, 25 |