| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 16.72M (8.61%) | 1.06M Increased by +6.32% | Dec 31, 25 |
| 2 | Farallon Capital Management, L.L.C. | 13.60M (7.01%) | -978.00K Decreased by -7.19% | Mar 31, 26 |
| 3 | BlackRock Inc | 11.21M (5.78%) | 2.29M Increased by +20.39% | Mar 31, 26 |
| 4 | HHG PLC | 9.77M (5.03%) | -2.54M Decreased by -25.98% | Mar 31, 26 |
| 5 | Baker Bros Advisors LP | 9.56M (4.92%) | 100.00K Increased by +1.05% | Mar 31, 26 |
| 6 | FMR Inc | 8.46M (4.36%) | -123.67K Decreased by -1.46% | Mar 31, 26 |
| 7 | Vanguard Capital Management, LLC | 8.36M (4.31%) | 8.36M Increased by +100.00% | Mar 31, 26 |
| 8 | Nextech Invest AG | 7.60M (3.92%) | 1.30M Increased by +17.16% | Dec 31, 24 |
| 9 | Nextech Invest, Ltd. | 7.60M (3.92%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Vanguard Portfolio Management, LLC | 7.50M (3.87%) | 7.50M Increased by +100.00% | Mar 31, 26 |
| 11 | Paradigm Biocapital Advisors LP | 6.66M (3.43%) | 11.30K Increased by +0.17% | Mar 31, 26 |
| 12 | Wellington Management Company LLP | 6.03M (3.11%) | -959.82K Decreased by -15.92% | Mar 31, 26 |
| 13 | EcoR1 Capital, LLC | 5.58M (2.87%) | -1.62M Decreased by -29.06% | Sep 30, 23 |
| 14 | Adage Capital Partners Gp LLC | 5.48M (2.82%) | 3.27M Increased by +59.72% | Mar 31, 26 |
| 15 | State Street Corporation | 5.39M (2.77%) | -867.34K Decreased by -16.10% | Mar 31, 24 |
| 16 | Bellevue Group AG | 5.01M (2.58%) | -568.12K Decreased by -11.35% | Dec 31, 25 |
| 17 | JPMorgan Chase & Co | 5.00M (2.57%) | 2.16M Increased by +43.22% | Sep 30, 25 |
| 18 | State Street Corp | 4.40M (2.27%) | 293.37K Increased by +6.66% | Mar 31, 26 |
| 19 | UBS Group AG | 4.39M (2.26%) | 1.30M Increased by +29.61% | Mar 31, 26 |
| 20 | Boxer Capital LLC | 4.28M (2.20%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 6.32M (3.26%) | 335.37K Increased by +5.31% | Apr 30, 26 |
| 2 | Vanguard US Total Market Shares ETF | 4.74M (2.44%) | 4.24K Increased by +0.09% | Sep 30, 24 |
| 3 | Vanguard Small Cap Index | 4.57M (2.35%) | 222.46K Increased by +4.87% | Apr 30, 26 |
| 4 | BB Biotech AG Ord | 4.37M (2.25%) | -484.46K Decreased by -11.08% | Dec 31, 24 |
| 5 | iShares Russell 2000 ETF | 4.27M (2.20%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | Fidelity Growth Compy Commingled Pl S | 3.41M (1.76%) | 18.32K Increased by +0.54% | Apr 30, 26 |
| 7 | Vanguard Health Care Inv | 2.58M (1.33%) | 191.45K Increased by +7.43% | Mar 31, 26 |
| 8 | Vanguard Small Cap Growth Index Inv | 2.56M (1.32%) | 129.82K Increased by +5.07% | Apr 30, 26 |
| 9 | Fidelity Growth Company Fund | 2.54M (1.31%) | 24.90K Increased by +0.98% | Apr 30, 26 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 2.22M (1.14%) | 183.97K Increased by +8.30% | Apr 30, 26 |
| 11 | Janus Henderson Mid Cap Growth MA | 2.09M (1.08%) | 2.09M Increased by +100.00% | Sep 30, 25 |
| 12 | SPDR® S&P Biotech ETF | 1.87M (0.96%) | 4.16K Increased by +0.22% | Aug 31, 25 |
| 13 | Fidelity Small Cap Index | 1.73M (0.89%) | 3.93K Increased by +0.23% | May 31, 25 |
| 14 | US Small-Cap Growth II Equity Comp | 1.66M (0.85%) | -539.14K Decreased by -32.51% | Jun 30, 25 |
| 15 | T. Rowe Price US Mid-Cap Growth Equity | 1.50M (0.77%) | 1.50M Increased by +100.00% | Jun 30, 25 |
| 16 | T. Rowe Price Mid-Cap Growth | 1.50M (0.77%) | -2.70K Decreased by -0.18% | Jul 31, 25 |
| 17 | Fidelity Growth Compy Commingled Pl O | 1.44M (0.74%) | 16.60K Increased by +1.15% | Aug 31, 24 |
| 18 | T. Rowe Price New Horizons | 1.36M (0.70%) | -242.13K Decreased by -17.86% | Jun 30, 25 |
| 19 | iShares Biotechnology ETF | 1.27M (0.65%) | 18.29K Increased by +1.44% | May 29, 26 |
| 20 | JPM Global Healthcare C (acc) USD | 1.24M (0.64%) | 0.00 Increased by 0.00% | Jan 31, 24 |