Healthcare [ 7/13 ] | Biotechnology [ 82/163 ]
NASDAQ | Common Stock
Repare Therapeutics Inc., a clinical-stage precision oncology company, engages in the discovery and development of therapeutics by using its synthetic lethality approach in Canada and the United States.
It uses its SNIPRx, a proprietary, genome-wide, and CRISPR-enabled platform, to discover, validate, and build a pipeline of SL-based therapeutics that focuses on genomic instability, including DNA damage repair.
The company's lead product candidate is Camonsertib (RP-3500), an oral small molecule inhibitor under Phase ½ development for the treatment of solid tumors with specific DNA damage repair-related genomic alterations.
It is also developing Lunresertib (RP-6306), a PKMYT1 Inhibitor, which is under Phase I/Ib clinical trial for tumors with genetic alterations characterized by CCNE1 amplification; RP-1664, an oral PLK4 inhibitor, under Phase 1 clinical trial designed to harness the synthetic lethal relationship with TRIM37 amplification or overexpression in solid tumors; and RP-3467, a polymerase theta adenosinetriphosphatase (ATPase) inhibitor, a SL target associated with BRCA mutations and other genomic alterations.
The company has license and collaboration agreement with Hoffmann-La Roche Inc. and F.
Hoffmann-La Roche Ltd; Bristol-Myers Squibb Company; New York University; with Foundation Medicine, Inc. for the provision of prospective genomic profiling of lunresertib alone or in combinations in genomically-defined patient populations; and Ono Pharmaceutical Co., as well as a clinical study and collaboration agreement with Debiopharm to explore the synthetic lethal combination of PKMYT1 and WEE1 inhibition in cancer.
Repare Therapeutics Inc. was incorporated in 2016 and is headquartered in Montréal, Canada.
| Reported date | EPSChange YoY | EstimateSurprise |
|---|---|---|
| May 7, 24 | 0.30 Increased by +136.14% | -0.78 Increased by +138.30% |
| Feb 28, 24 | -0.67 Increased by +10.67% | -0.36 Decreased by -86.11% |
| Nov 9, 23 | -0.45 Decreased by -126.32% | -0.86 Increased by +47.67% |
| Aug 9, 23 | -0.28 Increased by +69.23% | -0.78 Increased by +64.10% |
| May 9, 23 | -0.83 Increased by 0.00% | -0.81 Decreased by -2.47% |
| Feb 28, 23 | -0.75 Decreased by -7.14% | -0.72 Decreased by -4.17% |
| Nov 9, 22 | 1.71 Increased by +306.02% | -0.89 Increased by +292.13% |
| Aug 4, 22 | -0.91 Decreased by -28.17% | -0.85 Decreased by -7.06% |
| Fiscal ending date | RevenueChange YoY | IncomeChange YoY | ProfitChange YoY |
|---|---|---|---|
| Mar 31, 24 | 52.40 M Increased by +822.93% | 13.16 M Increased by +137.67% | Increased by +25.12% Increased by +104.08% |
| Dec 31, 23 | 13.05 M Decreased by -28.31% | -28.03 M Increased by +11.46% | Decreased by -214.84% Decreased by -23.50% |
| Sep 30, 23 | 2.16 M Decreased by -98.08% | -18.88 M Decreased by -125.02% | Decreased by -874.43% Decreased by -1.40 K% |
| Jun 30, 23 | 30.25 M Increased by +4.35 K% | -11.95 M Increased by +68.64% | Decreased by -39.49% Increased by +99.30% |
| Mar 31, 23 | 5.68 M Increased by +1.29 K% | -34.94 M Decreased by -0.53% | Decreased by -615.38% Increased by +92.78% |
| Dec 31, 22 | 18.20 M Increased by +164.62% | -31.66 M Decreased by -11.91% | Decreased by -173.96% Increased by +57.71% |
| Sep 30, 22 | 112.55 M Increased by +40.38 K% | 75.46 M Increased by +344.27% | Increased by +67.05% Increased by +100.60% |
| Jun 30, 22 | 679.00 K Increased by +143.37% | -38.09 M Decreased by -44.79% | Decreased by -5.61 K% Increased by +40.51% |