| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 16.19M (102.96%) | 570.73K Increased by +3.53% | Jun 30, 25 |
| 2 | Vanguard Group Inc | 13.65M (86.82%) | 429.49K Increased by +3.15% | Dec 31, 25 |
| 3 | BlackRock Inc | 12.85M (81.74%) | 3.65M Increased by +28.39% | Dec 31, 25 |
| 4 | T. Rowe Price Associates, Inc. | 9.79M (62.26%) | -1.02M Decreased by -10.43% | Sep 30, 25 |
| 5 | RTW INVESTMENTS, LLC | 9.62M (61.18%) | 871.92K Increased by +9.06% | Jun 30, 25 |
| 6 | Wellington Management Company LLP | 9.25M (58.84%) | -434.87K Decreased by -4.70% | Jun 30, 25 |
| 7 | RA Capital Management, LLC | 8.64M (54.97%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 8 | HHG PLC | 6.94M (44.14%) | -7.58M Decreased by -109.28% | Dec 31, 25 |
| 9 | Balyasny Asset Management LLC | 6.04M (38.42%) | 6.04M Increased by +100.00% | Dec 31, 25 |
| 10 | Pentwater Capital Management LP | 6.03M (38.33%) | 6.03M Increased by +100.00% | Dec 31, 25 |
| 11 | venBio Select Advisor LLC | 5.46M (34.70%) | -2.19M Decreased by -40.15% | Dec 31, 25 |
| 12 | COWEN AND COMPANY, LLC | 5.13M (32.63%) | -500.00K Decreased by -9.75% | Jun 30, 24 |
| 13 | State Street Corp | 4.10M (26.07%) | -790.75K Decreased by -19.30% | Dec 31, 25 |
| 14 | The Goldman Sachs Group Inc | 3.78M (24.02%) | 2.04M Increased by +54.13% | Dec 31, 25 |
| 15 | UBS O'Connor LLC | 3.72M (23.64%) | 3.72M Increased by +100.00% | Dec 31, 25 |
| 16 | The Toronto-Dominion Bank | 3.53M (22.47%) | 3.53M Increased by +100.00% | Jun 30, 25 |
| 17 | State Street Corporation | 3.46M (22.02%) | 23.49K Increased by +0.68% | Mar 31, 24 |
| 18 | Farallon Capital Management, L.L.C. | 3.23M (20.56%) | 3.23M Increased by +100.00% | Dec 31, 25 |
| 19 | Geode Capital Management, LLC | 3.12M (19.85%) | 262.73K Increased by +8.42% | Dec 31, 25 |
| 20 | NORGES BANK | 3.05M (19.38%) | 2.05M Increased by +67.33% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 5.49M (34.91%) | 109.14K Increased by +1.99% | Jul 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 4.86M (30.90%) | -69.00K Decreased by -1.42% | Aug 31, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 4.54M (28.85%) | 10.44K Increased by +0.23% | Jan 31, 26 |
| 4 | Fidelity Growth Company Fund | 3.99M (25.39%) | 77.74K Increased by +1.95% | Jul 31, 25 |
| 5 | US Small-Cap Growth II Equity Comp | 3.95M (25.13%) | -484.27K Decreased by -12.26% | Jun 30, 25 |
| 6 | T. Rowe Price New Horizons | 3.54M (22.49%) | -414.46K Decreased by -11.72% | Jul 31, 25 |
| 7 | Vanguard US Total Market Shares ETF | 3.53M (22.42%) | 3.12K Increased by +0.09% | Sep 30, 24 |
| 8 | Vanguard Small Cap Index | 3.25M (20.65%) | 3.86K Increased by +0.12% | Feb 28, 26 |
| 9 | Vanguard Health Care Inv | 2.83M (18.03%) | -196.40K Decreased by -6.93% | Jun 30, 25 |
| 10 | iShares Russell 2000 ETF | 2.77M (17.65%) | 2.77M Increased by +100.00% | Feb 28, 26 |
| 11 | Fidelity Growth Compy Commingled Pl 3 | 2.64M (16.82%) | 639.36K Increased by +24.17% | Jun 30, 23 |
| 12 | T. Rowe Price Health Sciences | 2.27M (14.45%) | -25.49K Decreased by -1.12% | Jul 31, 25 |
| 13 | BB Biotech AG Ord | 2.15M (13.69%) | 2.15M Increased by +100.00% | Sep 30, 25 |
| 14 | Vanguard Instl Ttl Stck Mkt Idx Tr | 1.95M (12.42%) | -61.60K Decreased by -3.15% | Mar 31, 23 |
| 15 | Fidelity® Growth Company | 1.85M (11.75%) | 542.45K Increased by +29.38% | Jun 30, 23 |
| 16 | RTW Biotech Opportunities Ord | 1.84M (11.71%) | 1.47M Increased by +79.91% | Jun 30, 25 |
| 17 | BlackRock Event Driven Equity Instl | 1.75M (11.16%) | 1.75M Increased by +100.00% | Jan 31, 26 |
| 18 | Janus Henderson Mid Cap Growth MA | 1.67M (10.62%) | 1.67M Increased by +100.00% | Sep 30, 25 |
| 19 | T. Rowe Price Integrated US SmCapGrEq | 1.58M (10.05%) | 789.87K Increased by +50.00% | Dec 31, 24 |
| 20 | SPDR® S&P Biotech ETF | 1.55M (9.85%) | 3.45K Increased by +0.22% | Aug 31, 25 |