| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 16.19M (15.01%) | 570.73K Increased by +3.53% | Jun 30, 25 |
| 2 | T. Rowe Price Associates, Inc. | 10.81M (10.02%) | -529.37K Decreased by -4.90% | Jun 30, 25 |
| 3 | HHG PLC | 10.78M (9.99%) | -649.38K Decreased by -6.03% | Jun 30, 25 |
| 4 | RTW INVESTMENTS, LLC | 9.62M (8.92%) | 871.92K Increased by +9.06% | Jun 30, 25 |
| 5 | BlackRock Inc | 9.34M (8.66%) | -580.64K Decreased by -6.22% | Jun 30, 25 |
| 6 | Wellington Management Company LLP | 9.25M (8.58%) | -434.87K Decreased by -4.70% | Jun 30, 25 |
| 7 | Vanguard Group Inc | 9.25M (8.58%) | 5.10K Increased by +0.06% | Jun 30, 25 |
| 8 | RA Capital Management, LLC | 7.27M (6.74%) | 965.62K Increased by +13.29% | Jun 30, 25 |
| 9 | venBio Select Advisor LLC | 7.05M (6.54%) | -575.00K Decreased by -8.16% | Jun 30, 25 |
| 10 | COWEN AND COMPANY, LLC | 5.13M (4.76%) | -500.00K Decreased by -9.75% | Jun 30, 24 |
| 11 | State Street Corp | 4.20M (3.90%) | -119.85K Decreased by -2.85% | Jun 30, 25 |
| 12 | The Toronto-Dominion Bank | 3.53M (3.28%) | 3.53M Increased by +100.00% | Jun 30, 25 |
| 13 | State Street Corporation | 3.46M (3.21%) | 23.49K Increased by +0.68% | Mar 31, 24 |
| 14 | Geode Capital Management, LLC | 2.85M (2.64%) | 92.72K Increased by +3.26% | Jun 30, 25 |
| 15 | Federated Hermes Inc | 2.36M (2.19%) | 0.00 Increased by 0.00% | Mar 31, 23 |
| 16 | Bank of America Corp | 1.84M (1.71%) | 264.83K Increased by +14.40% | Jun 30, 25 |
| 17 | Orbimed Advisors, LLC | 1.81M (1.68%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Casdin Capital, LLC | 1.77M (1.65%) | -270.00K Decreased by -15.21% | Jun 30, 25 |
| 19 | Polar Capital Holdings PLC | 1.77M (1.64%) | -18.48K Decreased by -1.04% | Jun 30, 25 |
| 20 | Boxer Capital LLC | 1.73M (1.60%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 5.49M (5.09%) | 109.14K Increased by +1.99% | Jul 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 4.86M (4.50%) | -69.00K Decreased by -1.42% | Aug 31, 24 |
| 3 | Fidelity Growth Company Fund | 3.99M (3.70%) | 77.74K Increased by +1.95% | Jul 31, 25 |
| 4 | US Small-Cap Growth II Equity Comp | 3.95M (3.66%) | -484.27K Decreased by -12.26% | Jun 30, 25 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 3.57M (3.31%) | -76.02K Decreased by -2.13% | Jul 31, 25 |
| 6 | T. Rowe Price New Horizons | 3.54M (3.28%) | -414.46K Decreased by -11.72% | Jul 31, 25 |
| 7 | Vanguard US Total Market Shares ETF | 3.53M (3.27%) | 3.12K Increased by +0.09% | Sep 30, 24 |
| 8 | Vanguard Health Care Inv | 2.83M (2.63%) | -196.40K Decreased by -6.93% | Jun 30, 25 |
| 9 | iShares Russell 2000 ETF | 2.76M (2.56%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 10 | Fidelity Growth Compy Commingled Pl 3 | 2.64M (2.45%) | 639.36K Increased by +24.17% | Jun 30, 23 |
| 11 | T. Rowe Price Health Sciences | 2.27M (2.11%) | -25.49K Decreased by -1.12% | Jul 31, 25 |
| 12 | Vanguard Instl Ttl Stck Mkt Idx Tr | 1.95M (1.81%) | -61.60K Decreased by -3.15% | Mar 31, 23 |
| 13 | Fidelity® Growth Company | 1.85M (1.71%) | 542.45K Increased by +29.38% | Jun 30, 23 |
| 14 | Janus Henderson Global Life Sciences | 1.64M (1.52%) | -28.26K Decreased by -1.73% | Jun 30, 25 |
| 15 | Janus Henderson Global Life Sciences D | 1.64M (1.52%) | -12.21K Decreased by -0.75% | Jun 30, 25 |
| 16 | T. Rowe Price Integrated US SmCapGrEq | 1.58M (1.47%) | 789.87K Increased by +50.00% | Dec 31, 24 |
| 17 | SPDR® S&P Biotech ETF | 1.55M (1.44%) | 3.45K Increased by +0.22% | Aug 31, 25 |
| 18 | Fidelity® Select Health Care | 1.40M (1.30%) | 900.00K Increased by +64.29% | Jun 30, 23 |
| 19 | Vanguard Small Cap Index | 1.39M (1.29%) | -8.34K Decreased by -0.60% | Jul 31, 25 |
| 20 | Janus Henderson Glb Life Scn I2 USD | 1.35M (1.25%) | 4.27K Increased by +0.32% | Jul 31, 25 |