| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 10.03M (11.26%) | 89.39K Increased by +0.89% | Dec 31, 24 |
| 2 | BlackRock Inc | 6.54M (7.33%) | 707.67K Increased by +10.83% | Dec 31, 24 |
| 3 | Sands Capital Management, LLC | 4.30M (4.82%) | -820.25K Decreased by -19.08% | Dec 31, 24 |
| 4 | State Street Corporation | 2.85M (3.20%) | -401.25K Decreased by -14.07% | Mar 31, 24 |
| 5 | State Street Corp | 2.72M (3.05%) | 58.55K Increased by +2.15% | Dec 31, 24 |
| 6 | T. Rowe Price Associates, Inc. | 2.51M (2.82%) | -556.23K Decreased by -22.14% | Dec 31, 24 |
| 7 | Wellington Management Company LLP | 2.46M (2.76%) | -1.71M Decreased by -69.50% | Dec 31, 24 |
| 8 | ClearBridge Advisors, LLC | 2.32M (2.61%) | -104.77K Decreased by -4.51% | Dec 31, 24 |
| 9 | Federated Hermes Inc | 2.05M (2.30%) | -60.90K Decreased by -2.97% | Dec 31, 24 |
| 10 | RTW INVESTMENTS, LLC | 1.97M (2.21%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | Millennium Management LLC | 1.85M (2.08%) | 1.14M Increased by +61.75% | Jun 30, 24 |
| 12 | Rock Springs Capital Management LP | 1.74M (1.95%) | -238.46K Decreased by -13.71% | Dec 31, 24 |
| 13 | Amvescap Plc. | 1.70M (1.91%) | 25.49K Increased by +1.50% | Dec 31, 24 |
| 14 | Deutsche Bank AG | 1.69M (1.90%) | 4.14K Increased by +0.24% | Dec 31, 24 |
| 15 | Alkeon Capital Management, LLC | 1.69M (1.89%) | -1.32M Decreased by -78.56% | Dec 31, 24 |
| 16 | AllianceBernstein L.P. | 1.63M (1.83%) | 81.67K Increased by +5.02% | Dec 31, 24 |
| 17 | Baker Bros Advisors LP | 1.58M (1.77%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 1.56M (1.75%) | -8.29K Decreased by -0.53% | Dec 31, 24 |
| 19 | Vestal Point Capital LP | 1.50M (1.68%) | 750.00K Increased by +50.00% | Dec 31, 24 |
| 20 | venBio Select Advisor LLC | 1.50M (1.68%) | 750.00K Increased by +50.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.77M (3.11%) | 2.48K Increased by +0.09% | Feb 28, 25 |
| 2 | Vanguard Small Cap Index | 2.24M (2.51%) | 1.83K Increased by +0.08% | Feb 28, 25 |
| 3 | Sands Capital Select Growth TE Inst EQ | 2.09M (2.35%) | -319.65K Decreased by -15.29% | Dec 31, 24 |
| 4 | Vanguard Explorer Inv | 2.00M (2.25%) | 24.46K Increased by +1.22% | Dec 31, 24 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 1.40M (1.57%) | 2.06K Increased by +0.15% | Feb 28, 25 |
| 6 | Hartford MidCap Y | 1.28M (1.44%) | -24.56K Decreased by -1.91% | Oct 31, 24 |
| 7 | Vanguard Small Cap Growth Index Inv | 1.26M (1.41%) | -6.83K Decreased by -0.54% | Feb 28, 25 |
| 8 | Vanguard Health Care Inv | 1.25M (1.40%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | DWS Vermögensbildungsfonds I LD | 1.18M (1.32%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 10 | First Trust NYSE Arca Biotech ETF | 1.14M (1.28%) | -92.00 Decreased by -0.01% | Dec 28, 23 |
| 11 | Federated Hermes Kaufmann Small Cap A | 1.09M (1.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | Federated Hermes Kaufmann Small Cap Grow | 1.09M (1.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | SPDR® S&P Biotech ETF | 1.09M (1.22%) | -11.66K Decreased by -1.07% | Mar 31, 25 |
| 14 | Fidelity® Select Biotechnology | 1.04M (1.17%) | -188.62K Decreased by -18.15% | Nov 30, 23 |
| 15 | T. Rowe Price Integrated US SmCapGrEq | 1.02M (1.15%) | 659.69K Increased by +64.59% | Dec 31, 24 |
| 16 | Federated Hermes Kaufmann Growth | 932.50K (1.05%) | -58.90K Decreased by -6.32% | Dec 31, 24 |
| 17 | Federated Hermes Kaufmann R | 932.50K (1.05%) | -58.90K Decreased by -6.32% | Dec 31, 24 |
| 18 | T. Rowe Price Health Sciences | 905.97K (1.02%) | 95.00K Increased by +10.49% | Feb 28, 25 |
| 19 | Touchstone Sands Capital Select Growth Z | 815.14K (0.91%) | -195.45K Decreased by -23.98% | Dec 31, 24 |
| 20 | T. Rowe Price New Horizons | 794.59K (0.89%) | 0.00 Increased by 0.00% | Feb 28, 25 |