| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.69M (55.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | RTW INVESTMENTS, LLC | 3.19M (16.66%) | 3.19M Increased by +100.00% | Dec 31, 24 |
| 3 | Point72 Asset Management, L.P. | 2.76M (14.40%) | 83.23K Increased by +3.02% | Jun 30, 25 |
| 4 | Millennium Management LLC | 1.51M (7.87%) | 476.18K Increased by +31.55% | Jun 30, 25 |
| 5 | Viking Global Investors LP | 1.48M (7.73%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Adage Capital Partners Gp LLC | 1.35M (7.04%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Vanguard Group Inc | 937.02K (4.89%) | 37.29K Increased by +3.98% | Jun 30, 25 |
| 8 | Perceptive Advisors LLC | 829.54K (4.33%) | -580.90K Decreased by -70.03% | Dec 31, 24 |
| 9 | LAURION CAPITAL MANAGEMENT LP | 810.76K (4.23%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Woodline Partners LP | 691.53K (3.61%) | -89.37K Decreased by -12.92% | Jun 30, 25 |
| 11 | Orbimed Advisors, LLC | 653.02K (3.41%) | -144.34K Decreased by -22.10% | Dec 31, 24 |
| 12 | Samsara BioCapital, LLC | 651.05K (3.40%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | BlackRock Inc | 648.02K (3.38%) | -646.23K Decreased by -99.72% | Jun 30, 25 |
| 14 | Sofinnova Ventures | 561.13K (2.93%) | 57.50K Increased by +10.25% | Jun 30, 24 |
| 15 | Polar Capital Holdings PLC | 531.10K (2.77%) | 531.10K Increased by +100.00% | Jun 30, 24 |
| 16 | HHG PLC | 522.26K (2.72%) | -1.81M Decreased by -347.39% | Dec 31, 24 |
| 17 | Octagon Capital Advisors LP | 376.12K (1.96%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 18 | Suvretta Capital Management, LLC | 300.00K (1.57%) | -1.36M Decreased by -453.64% | Jun 30, 25 |
| 19 | Prosight Management, LP | 243.98K (1.27%) | 243.98K Increased by +100.00% | Jun 30, 25 |
| 20 | State Street Corporation | 240.98K (1.26%) | 24.07K Increased by +9.99% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Select Biotechnology | 737.00K (3.85%) | 444.16K Increased by +60.27% | Nov 30, 23 |
| 2 | Vanguard US Total Market Shares ETF | 492.80K (2.57%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 472.39K (2.46%) | -10.32K Decreased by -2.19% | Jul 31, 25 |
| 4 | Biotech Growth Ord | 409.12K (2.13%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 5 | Fidelity Series Small Cap Opps | 383.52K (2.00%) | -229.55K Decreased by -59.85% | Oct 31, 23 |
| 6 | Fidelity® Series Small Cap Opps | 383.52K (2.00%) | -229.55K Decreased by -59.85% | Oct 31, 23 |
| 7 | Fidelity Small Cap Growth | 225.69K (1.18%) | -117.21K Decreased by -51.93% | Oct 31, 23 |
| 8 | Fidelity® Small Cap Growth | 225.69K (1.18%) | -117.21K Decreased by -51.93% | Oct 31, 23 |
| 9 | Fidelity Stock Selector Small Cap | 213.36K (1.11%) | -118.10K Decreased by -55.35% | Oct 31, 23 |
| 10 | Fidelity® Stock Selector Small Cap | 213.36K (1.11%) | -118.10K Decreased by -55.35% | Oct 31, 23 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 198.86K (1.04%) | -90.61K Decreased by -45.57% | Jul 31, 25 |
| 12 | iShares Biotechnology ETF | 171.31K (0.89%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 13 | Fidelity Small Cap Index | 155.98K (0.81%) | 0.00 Increased by 0.00% | May 31, 25 |
| 14 | Vanguard Balanced Index Inv | 148.11K (0.77%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 15 | Fidelity® Small Cap Index | 94.09K (0.49%) | 3.49K Increased by +3.70% | Oct 31, 23 |
| 16 | Fidelity Extended Market Index | 92.45K (0.48%) | -761.00 Decreased by -0.82% | Jul 31, 25 |
| 17 | State St Russell Sm/Mid Cp® Indx NL Cl C | 90.99K (0.47%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 90.99K (0.47%) | 0.00 Increased by 0.00% | May 31, 25 |
| 19 | iShares Russell 2000 ETF | 88.89K (0.46%) | -3.66K Decreased by -4.12% | Jun 30, 25 |
| 20 | Bridgeway Ultra-Small Company Market | 78.92K (0.41%) | 35.00K Increased by +44.35% | Jun 30, 25 |