| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 10.39M (17.39%) | 5.36M Increased by +51.64% | Mar 31, 26 |
| 2 | Paradigm Biocapital Advisors LP | 8.02M (13.43%) | 476.40K Increased by +5.94% | Mar 31, 26 |
| 3 | Bain Capital Life Sciences Investors, LLC | 7.47M (12.51%) | -1.04M Decreased by -13.85% | Mar 31, 26 |
| 4 | HHG PLC | 7.11M (11.90%) | 398.29K Increased by +5.60% | Mar 31, 26 |
| 5 | BlackRock Inc | 5.65M (9.46%) | 88.88K Increased by +1.57% | Mar 31, 26 |
| 6 | Bvf Inc | 5.30M (8.87%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Siren, L.L.C. | 4.76M (7.97%) | 1.46M Increased by +30.61% | Mar 31, 26 |
| 8 | State Street Corp | 3.94M (6.59%) | 2.05M Increased by +52.15% | Mar 31, 26 |
| 9 | Cormorant Asset Management, LLC | 3.90M (6.53%) | 1.15M Increased by +29.49% | Mar 31, 26 |
| 10 | Vanguard Group Inc | 3.56M (5.96%) | 364.04K Increased by +10.22% | Dec 31, 25 |
| 11 | Deep Track Capital, LP | 3.47M (5.81%) | 27.34K Increased by +0.79% | Sep 30, 25 |
| 12 | Logos Global Management LP | 3.21M (5.37%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 13 | State Street Corporation | 3.18M (5.32%) | 2.51M Increased by +78.82% | Mar 31, 24 |
| 14 | Vanguard Capital Management, LLC | 3.08M (5.16%) | 3.08M Increased by +100.00% | Mar 31, 26 |
| 15 | RA Capital Management, LLC | 2.60M (4.35%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | MPM Oncology Impact Management LP | 2.38M (3.98%) | -551.68K Decreased by -23.19% | Jun 30, 25 |
| 17 | Pictet Asset Manangement SA | 1.88M (3.15%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Jennison Associates LLC | 1.82M (3.05%) | 858.13K Increased by +47.09% | Mar 31, 26 |
| 19 | venBio Select Advisor LLC | 1.65M (2.77%) | 1.65M Increased by +100.00% | Dec 31, 24 |
| 20 | Vestal Point Capital LP | 1.65M (2.76%) | 1.65M Increased by +100.00% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | State Street® SPDR® S&P® Biotech ETF | 2.74M (4.58%) | -16.83K Decreased by -0.62% | May 31, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.43M (4.06%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 3 | iShares Russell 2000 ETF | 1.67M (2.79%) | 15.39K Increased by +0.92% | May 29, 26 |
| 4 | Polar Capital Healthcare Opports Inc | 1.60M (2.68%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 5 | Fidelity Select Health Care | 1.50M (2.51%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 6 | Vanguard US Total Market Shares ETF | 1.49M (2.49%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Strategic Advisers Fidelity US TtlStk | 1.11M (1.86%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 8 | Belfius Equities Cure C Cap | 1.04M (1.73%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 9 | Pictet-Biotech P USD | 931.49K (1.56%) | 11.40K Increased by +1.22% | May 31, 25 |
| 10 | Franklin Small Cap Growth SMA | 917.80K (1.54%) | 917.80K Increased by +100.00% | Jun 30, 25 |
| 11 | Franklin Small Cap Growth Adv | 893.20K (1.50%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | Janus Henderson Hrzn Biotec E2 USD | 877.34K (1.47%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 13 | SPDR® S&P Biotech ETF | 864.83K (1.45%) | -5.26K Decreased by -0.61% | Feb 28, 25 |
| 14 | Candriam Global Equities Oncology | 860.55K (1.44%) | 187.55K Increased by +21.79% | Sep 30, 24 |
| 15 | Pictet-Global Megatrend Sel I USD | 795.67K (1.33%) | 12.16K Increased by +1.53% | May 31, 25 |
| 16 | Columbia Small Cap Value Discv A | 778.62K (1.30%) | 21.40K Increased by +2.75% | Jul 31, 25 |
| 17 | Columbia Small Cap Value I A | 778.62K (1.30%) | 21.40K Increased by +2.75% | Jul 31, 25 |
| 18 | Fidelity Advisor Biotechnology I | 777.20K (1.30%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 19 | Columbia Small Cap Value Discovery Fund | 757.22K (1.27%) | 241.23K Increased by +31.86% | Jun 30, 25 |
| 20 | Columbia Small Cap Value I | 757.22K (1.27%) | 241.23K Increased by +31.86% | Jun 30, 25 |