| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bain Capital Life Sciences Investors, LLC | 8.51M (14.33%) | 1.66M Increased by +19.56% | Dec 31, 25 |
| 2 | Paradigm Biocapital Advisors LP | 8.02M (13.51%) | 476.40K Increased by +5.94% | Mar 31, 26 |
| 3 | HHG PLC | 6.71M (11.30%) | 3.12M Increased by +46.56% | Dec 31, 25 |
| 4 | BlackRock Inc | 5.56M (9.37%) | 836.87K Increased by +15.04% | Dec 31, 25 |
| 5 | Bvf Inc | 5.30M (8.92%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | FMR Inc | 5.02M (8.46%) | 4.99M Increased by +99.41% | Dec 31, 25 |
| 7 | Cormorant Asset Management, LLC | 3.90M (6.57%) | 1.15M Increased by +29.49% | Mar 31, 26 |
| 8 | Vanguard Group Inc | 3.56M (6.00%) | 364.04K Increased by +10.22% | Dec 31, 25 |
| 9 | Deep Track Capital, LP | 3.47M (5.84%) | 27.34K Increased by +0.79% | Sep 30, 25 |
| 10 | Siren, L.L.C. | 3.30M (5.56%) | 3.30M Increased by +100.00% | Dec 31, 25 |
| 11 | Logos Global Management LP | 3.21M (5.40%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | State Street Corporation | 3.18M (5.35%) | 2.51M Increased by +78.82% | Mar 31, 24 |
| 13 | RA Capital Management, LLC | 2.60M (4.38%) | 2.60M Increased by +100.00% | Dec 31, 25 |
| 14 | MPM Oncology Impact Management LP | 2.38M (4.01%) | -551.68K Decreased by -23.19% | Jun 30, 25 |
| 15 | Lightspeed Management Co LLC | 1.93M (3.25%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 16 | State Street Corp | 1.88M (3.17%) | 790.83K Increased by +41.97% | Dec 31, 25 |
| 17 | Pictet Asset Manangement SA | 1.88M (3.16%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Jennison Associates LLC | 1.82M (3.07%) | 858.13K Increased by +47.09% | Mar 31, 26 |
| 19 | venBio Select Advisor LLC | 1.65M (2.78%) | 1.65M Increased by +100.00% | Dec 31, 24 |
| 20 | Vestal Point Capital LP | 1.65M (2.78%) | 1.65M Increased by +100.00% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | State Street® SPDR® S&P® Biotech ETF | 2.73M (4.60%) | -19.62K Decreased by -0.72% | Apr 30, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.43M (4.09%) | 183.65K Increased by +7.57% | Mar 31, 26 |
| 3 | iShares Russell 2000 ETF | 1.65M (2.78%) | 13.91K Increased by +0.84% | Apr 30, 26 |
| 4 | Polar Capital Healthcare Opports Inc | 1.60M (2.70%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | Fidelity Select Health Care | 1.50M (2.53%) | 150.00K Increased by +10.00% | Mar 31, 26 |
| 6 | Vanguard US Total Market Shares ETF | 1.49M (2.51%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Strategic Advisers Fidelity US TtlStk | 1.11M (1.87%) | 110.40K Increased by +9.94% | Mar 31, 26 |
| 8 | Belfius Equities Cure C Cap | 1.04M (1.74%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 9 | Pictet-Biotech P USD | 931.49K (1.57%) | 11.40K Increased by +1.22% | May 31, 25 |
| 10 | Franklin Small Cap Growth SMA | 917.80K (1.55%) | 917.80K Increased by +100.00% | Jun 30, 25 |
| 11 | Franklin Small Cap Growth Adv | 893.20K (1.50%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | Janus Henderson Hrzn Biotec E2 USD | 877.34K (1.48%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 13 | SPDR® S&P Biotech ETF | 864.83K (1.46%) | -5.26K Decreased by -0.61% | Feb 28, 25 |
| 14 | Candriam Global Equities Oncology | 860.55K (1.45%) | 187.55K Increased by +21.79% | Sep 30, 24 |
| 15 | Pictet-Global Megatrend Sel I USD | 795.67K (1.34%) | 12.16K Increased by +1.53% | May 31, 25 |
| 16 | Columbia Small Cap Value Discv A | 778.62K (1.31%) | 21.40K Increased by +2.75% | Jul 31, 25 |
| 17 | Columbia Small Cap Value I A | 778.62K (1.31%) | 21.40K Increased by +2.75% | Jul 31, 25 |
| 18 | Fidelity Advisor Biotechnology I | 777.20K (1.31%) | -5.60K Decreased by -0.72% | Mar 31, 26 |
| 19 | Columbia Small Cap Value Discovery Fund | 757.22K (1.28%) | 241.23K Increased by +31.86% | Jun 30, 25 |
| 20 | Columbia Small Cap Value I | 757.22K (1.28%) | 241.23K Increased by +31.86% | Jun 30, 25 |