| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Deerfield Management Co | 17.99M (43.58%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | FMR Inc | 9.94M (24.07%) | 282.87K Increased by +2.85% | Mar 31, 25 |
| 3 | Paradigm Biocapital Advisors LP | 5.27M (12.77%) | -93.95K Decreased by -1.78% | Mar 31, 25 |
| 4 | Vanguard Group Inc | 4.44M (10.76%) | -60.03K Decreased by -1.35% | Mar 31, 25 |
| 5 | BlackRock Inc | 3.75M (9.08%) | -103.22K Decreased by -2.75% | Mar 31, 25 |
| 6 | COMMODORE CAPITAL LP | 1.85M (4.49%) | 233.40K Increased by +12.58% | Mar 31, 25 |
| 7 | State Street Corporation | 1.70M (4.12%) | 440.77K Increased by +25.91% | Dec 31, 23 |
| 8 | Perceptive Advisors LLC | 1.63M (3.96%) | -986.01K Decreased by -60.34% | Mar 31, 25 |
| 9 | T. Rowe Price Associates, Inc. | 1.45M (3.51%) | 152.69K Increased by +10.53% | Mar 31, 25 |
| 10 | Bain Capital Life Sciences Investors, LLC | 1.45M (3.51%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Wellington Management Company LLP | 1.44M (3.49%) | 157.81K Increased by +10.94% | Mar 31, 25 |
| 12 | State Street Corp | 1.43M (3.47%) | -59.02K Decreased by -4.13% | Mar 31, 25 |
| 13 | Fairmount Funds Management LLC | 1.32M (3.19%) | -369.40K Decreased by -28.03% | Dec 31, 24 |
| 14 | HHG PLC | 1.31M (3.17%) | 1.29M Increased by +98.73% | Mar 31, 25 |
| 15 | Woodline Partners LP | 1.21M (2.92%) | 604.00 Increased by +0.05% | Mar 31, 25 |
| 16 | Boxer Capital LLC | 1.12M (2.71%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | Boxer Capital Management, LLC | 1.12M (2.71%) | 1.12M Increased by +100.00% | Dec 31, 24 |
| 18 | Polar Capital Holdings PLC | 946.72K (2.29%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | Geode Capital Management, LLC | 893.46K (2.16%) | 21.97K Increased by +2.46% | Mar 31, 25 |
| 20 | BRAIDWELL LP | 840.95K (2.04%) | 599.71K Increased by +71.31% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl O | 2.48M (6.00%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 2.42M (5.87%) | 11.35K Increased by +0.47% | Mar 31, 25 |
| 3 | Fidelity Growth Company Fund | 1.71M (4.14%) | -43.90K Decreased by -2.57% | Mar 31, 25 |
| 4 | Fidelity® Growth Company | 1.60M (3.88%) | 36.30K Increased by +2.27% | Nov 30, 23 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.49M (3.60%) | 16.26K Increased by +1.09% | Apr 30, 25 |
| 6 | Vanguard Small Cap Index | 1.16M (2.82%) | 6.11K Increased by +0.53% | Apr 30, 25 |
| 7 | iShares Russell 2000 ETF | 868.25K (2.10%) | 147.00 Increased by +0.02% | Apr 30, 25 |
| 8 | Vanguard Small Cap Value Index Inv | 751.64K (1.82%) | 2.37K Increased by +0.32% | Apr 30, 25 |
| 9 | Fidelity Select Health Care | 700.00K (1.70%) | 30.00K Increased by +4.29% | Mar 31, 25 |
| 10 | Fidelity® Growth Company K6 | 617.41K (1.50%) | 540.00 Increased by +0.09% | Nov 30, 23 |
| 11 | SPDR® S&P Biotech ETF | 611.97K (1.48%) | -8.96K Decreased by -1.46% | Apr 30, 25 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 587.15K (1.42%) | 4.09K Increased by +0.70% | Apr 30, 25 |
| 13 | Fidelity® Small Cap Growth | 549.27K (1.33%) | -667.00 Decreased by -0.12% | Oct 31, 23 |
| 14 | Fidelity Growth Company K6 | 517.68K (1.25%) | -8.20K Decreased by -1.58% | Mar 31, 25 |
| 15 | Fidelity Small Cap Growth | 512.71K (1.24%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 16 | Polar Capital Biotech S Inc | 500.00K (1.21%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Fidelity® Series Growth Company | 472.26K (1.14%) | 10.13K Increased by +2.15% | Nov 30, 23 |
| 18 | Fidelity Series Growth Company | 469.43K (1.14%) | 28.10K Increased by +5.99% | Mar 31, 25 |
| 19 | T. Rowe Price New Horizons | 469.25K (1.14%) | 15.15K Increased by +3.23% | Mar 31, 25 |
| 20 | US Small-Cap Growth II Equity Comp | 469.25K (1.14%) | 15.02K Increased by +3.20% | Mar 31, 25 |