| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Deerfield Management Co | 17.99M (43.68%) | -2.00M Decreased by -11.12% | Dec 31, 24 |
| 2 | FMR Inc | 9.65M (23.44%) | -26.00 Decreased by -0.00% | Dec 31, 24 |
| 3 | Paradigm Biocapital Advisors LP | 5.36M (13.02%) | 363.38K Increased by +6.78% | Dec 31, 24 |
| 4 | Vanguard Group Inc | 4.50M (10.93%) | 366.24K Increased by +8.14% | Dec 31, 24 |
| 5 | BlackRock Inc | 3.85M (9.35%) | 226.60K Increased by +5.88% | Dec 31, 24 |
| 6 | Perceptive Advisors LLC | 2.62M (6.36%) | -359.26K Decreased by -13.71% | Dec 31, 24 |
| 7 | State Street Corporation | 1.70M (4.13%) | 440.77K Increased by +25.91% | Dec 31, 23 |
| 8 | COMMODORE CAPITAL LP | 1.62M (3.94%) | 681.60K Increased by +42.03% | Dec 31, 24 |
| 9 | State Street Corp | 1.49M (3.62%) | 246.58K Increased by +16.55% | Dec 31, 24 |
| 10 | Bain Capital Life Sciences Investors, LLC | 1.45M (3.51%) | -1.25M Decreased by -86.37% | Dec 31, 24 |
| 11 | Fairmount Funds Management LLC | 1.32M (3.20%) | -369.40K Decreased by -28.03% | Dec 31, 24 |
| 12 | T. Rowe Price Associates, Inc. | 1.30M (3.15%) | 215.63K Increased by +16.61% | Dec 31, 24 |
| 13 | Wellington Management Company LLP | 1.28M (3.12%) | 272.74K Increased by +21.23% | Dec 31, 24 |
| 14 | Woodline Partners LP | 1.20M (2.93%) | 11.25K Increased by +0.93% | Dec 31, 24 |
| 15 | Boxer Capital LLC | 1.12M (2.72%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | Boxer Capital Management, LLC | 1.12M (2.72%) | 1.12M Increased by +100.00% | Dec 31, 24 |
| 17 | Polar Capital Holdings PLC | 946.72K (2.30%) | 584.22K Increased by +61.71% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 871.49K (2.12%) | 15.88K Increased by +1.82% | Dec 31, 24 |
| 19 | venBio Select Advisor LLC | 812.50K (1.97%) | -787.50K Decreased by -96.92% | Sep 30, 23 |
| 20 | Driehaus Capital Management LLC | 793.42K (1.93%) | -70.54K Decreased by -8.89% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl O | 2.48M (6.01%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 2.42M (5.88%) | 11.35K Increased by +0.47% | Mar 31, 25 |
| 3 | Fidelity Growth Company Fund | 1.71M (4.15%) | -43.90K Decreased by -2.57% | Mar 31, 25 |
| 4 | Fidelity® Growth Company | 1.60M (3.89%) | 36.30K Increased by +2.27% | Nov 30, 23 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.47M (3.57%) | 5.53K Increased by +0.38% | Mar 31, 25 |
| 6 | Vanguard Small Cap Index | 1.16M (2.81%) | -16.16K Decreased by -1.40% | Mar 31, 25 |
| 7 | iShares Russell 2000 ETF | 868.11K (2.11%) | -7.06K Decreased by -0.81% | Apr 29, 25 |
| 8 | Vanguard Small Cap Value Index Inv | 749.27K (1.82%) | -23.17K Decreased by -3.09% | Mar 31, 25 |
| 9 | Fidelity Select Health Care | 700.00K (1.70%) | 30.00K Increased by +4.29% | Mar 31, 25 |
| 10 | Fidelity® Growth Company K6 | 617.41K (1.50%) | 540.00 Increased by +0.09% | Nov 30, 23 |
| 11 | SPDR® S&P Biotech ETF | 610.23K (1.48%) | -10.71K Decreased by -1.75% | Apr 30, 25 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 583.07K (1.42%) | -1.71K Decreased by -0.29% | Mar 31, 25 |
| 13 | Fidelity® Small Cap Growth | 549.27K (1.33%) | -667.00 Decreased by -0.12% | Oct 31, 23 |
| 14 | Fidelity Growth Company K6 | 525.88K (1.28%) | -103.28K Decreased by -19.64% | Feb 28, 25 |
| 15 | Fidelity Small Cap Growth | 512.71K (1.24%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 16 | Polar Capital Biotech S Inc | 500.00K (1.21%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Fidelity® Series Growth Company | 472.26K (1.15%) | 10.13K Increased by +2.15% | Nov 30, 23 |
| 18 | T. Rowe Price New Horizons | 469.25K (1.14%) | 15.15K Increased by +3.23% | Mar 31, 25 |
| 19 | US Small-Cap Growth II Equity Comp | 469.25K (1.14%) | 15.02K Increased by +3.20% | Mar 31, 25 |
| 20 | Fidelity Series Growth Company | 441.32K (1.07%) | -94.00K Decreased by -21.30% | Feb 28, 25 |