| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Deerfield Management Co | 17.25M (35.12%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | FMR Inc | 9.27M (18.89%) | -1.58M Decreased by -17.01% | Mar 31, 26 |
| 3 | Paradigm Biocapital Advisors LP | 5.32M (10.84%) | 55.00K Increased by +1.03% | Mar 31, 26 |
| 4 | Vanguard Group Inc | 5.24M (10.68%) | 639.26K Increased by +12.19% | Dec 31, 25 |
| 5 | BlackRock Inc | 4.82M (9.82%) | 19.52K Increased by +0.40% | Mar 31, 26 |
| 6 | JPMorgan Chase & Co | 3.09M (6.29%) | 883.10K Increased by +28.59% | Mar 31, 26 |
| 7 | RA Capital Management, LLC | 2.53M (5.16%) | 654.09K Increased by +25.81% | Mar 31, 26 |
| 8 | Vanguard Portfolio Management, LLC | 2.50M (5.09%) | 2.50M Increased by +100.00% | Mar 31, 26 |
| 9 | Wellington Management Company LLP | 2.47M (5.03%) | 8.67K Increased by +0.35% | Mar 31, 26 |
| 10 | Vanguard Capital Management, LLC | 2.43M (4.95%) | 2.43M Increased by +100.00% | Mar 31, 26 |
| 11 | T. Rowe Price Associates, Inc. | 2.06M (4.19%) | -90.81K Decreased by -4.42% | Mar 31, 26 |
| 12 | State Street Corp | 2.04M (4.15%) | 171.16K Increased by +8.41% | Mar 31, 26 |
| 13 | Polar Capital Holdings PLC | 1.83M (3.73%) | 294.39K Increased by +16.08% | Mar 31, 26 |
| 14 | State Street Corporation | 1.70M (3.46%) | 440.77K Increased by +25.91% | Dec 31, 23 |
| 15 | Perceptive Advisors LLC | 1.58M (3.22%) | -84.60K Decreased by -5.35% | Mar 31, 26 |
| 16 | Bain Capital Life Sciences Investors, LLC | 1.45M (2.95%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 17 | T. Rowe Price Investment Management,Inc. | 1.41M (2.88%) | -275.10K Decreased by -19.46% | Mar 31, 26 |
| 18 | Deep Track Capital, LP | 1.38M (2.80%) | 1.38M Increased by +100.00% | Mar 31, 26 |
| 19 | Geode Capital Management, LLC | 1.30M (2.64%) | 59.87K Increased by +4.61% | Mar 31, 26 |
| 20 | HHG PLC | 1.24M (2.52%) | -261.80K Decreased by -21.15% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl O | 2.48M (5.04%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.75M (3.57%) | 5.84K Increased by +0.33% | Apr 30, 26 |
| 3 | Fidelity® Growth Company | 1.60M (3.26%) | 36.30K Increased by +2.27% | Nov 30, 23 |
| 4 | Vanguard Small Cap Index | 1.26M (2.58%) | -2.52K Decreased by -0.20% | Apr 30, 26 |
| 5 | iShares Russell 2000 ETF | 1.20M (2.44%) | 11.08K Increased by +0.92% | May 29, 26 |
| 6 | Vanguard Health Care Inv | 1.05M (2.15%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Polar Capital Biotech S Inc | 964.07K (1.96%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 8 | State Street® SPDR® S&P® Biotech ETF | 937.41K (1.91%) | -5.78K Decreased by -0.62% | May 31, 26 |
| 9 | Strategic Advisers Fidelity US TtlStk | 844.55K (1.72%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 10 | Fidelity Growth Company Fund | 833.28K (1.70%) | -380.00K Decreased by -45.60% | Apr 30, 26 |
| 11 | Fidelity Growth Compy Commingled Pl S | 820.28K (1.67%) | -554.59K Decreased by -67.61% | Apr 30, 26 |
| 12 | Vanguard Small Cap Value Index Inv | 812.02K (1.65%) | 5.63K Increased by +0.69% | Apr 30, 26 |
| 13 | Fidelity Select Health Care | 700.00K (1.43%) | -28.00K Decreased by -4.00% | Apr 30, 26 |
| 14 | JPMorgan Growth Advantage A | 698.06K (1.42%) | -11.29K Decreased by -1.62% | Apr 30, 26 |
| 15 | Fidelity® Growth Company K6 | 617.41K (1.26%) | 540.00 Increased by +0.09% | Nov 30, 23 |
| 16 | JPM US Mid Cap Growth-Composite | 607.45K (1.24%) | -5.60K Decreased by -0.92% | Mar 31, 26 |
| 17 | JPMorgan Mid Cap Growth I | 604.20K (1.23%) | -3.25K Decreased by -0.54% | Apr 30, 26 |
| 18 | Polar Capital Healthcare Opports Inc | 600.04K (1.22%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 592.41K (1.21%) | 4.72K Increased by +0.80% | Apr 30, 26 |
| 20 | SPDR® S&P Biotech ETF | 590.59K (1.20%) | 1.31K Increased by +0.22% | Aug 31, 25 |