| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 13.45M (8.30%) | -4.88M Decreased by -36.31% | Dec 31, 24 |
| 2 | RA Capital Management, LLC | 7.51M (4.63%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | T. Rowe Price Associates, Inc. | 6.81M (4.20%) | -4.36M Decreased by -64.00% | Dec 31, 24 |
| 4 | Hillhouse Capital Advisors, Ltd. | 5.98M (3.69%) | -651.95K Decreased by -10.89% | Dec 31, 24 |
| 5 | Westfield Capital Management Company, L.P. | 5.71M (3.53%) | 675.19K Increased by +11.82% | Dec 31, 24 |
| 6 | Westfield Capital Management Company, LP | 5.04M (3.11%) | 266.30K Increased by +5.29% | Sep 30, 24 |
| 7 | BlackRock Inc | 4.61M (2.84%) | 113.37K Increased by +2.46% | Dec 31, 24 |
| 8 | Suvretta Capital Management, LLC | 3.50M (2.16%) | 3.50M Increased by +100.00% | Dec 31, 24 |
| 9 | Amvescap Plc. | 3.31M (2.04%) | 1.02M Increased by +30.89% | Dec 31, 24 |
| 10 | BRAIDWELL LP | 2.98M (1.84%) | 1.44M Increased by +48.23% | Dec 31, 24 |
| 11 | Citadel Advisors Llc | 2.90M (1.79%) | 1.59M Increased by +54.68% | Dec 31, 24 |
| 12 | Goldman Sachs Group Inc | 2.49M (1.54%) | 2.04M Increased by +81.67% | Dec 31, 24 |
| 13 | Capital World Investors | 2.39M (1.47%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 14 | Massachusetts Financial Services Company | 2.26M (1.40%) | -11.60K Decreased by -0.51% | Dec 31, 24 |
| 15 | Capital Research & Mgmt Co - Division 3 | 2.16M (1.33%) | -62.88K Decreased by -2.91% | Dec 31, 24 |
| 16 | HHG PLC | 2.16M (1.33%) | -28.89K Decreased by -1.34% | Dec 31, 24 |
| 17 | Wellington Management Company LLP | 2.12M (1.31%) | 84.41K Increased by +3.98% | Dec 31, 24 |
| 18 | Adage Capital Partners Gp LLC | 1.71M (1.05%) | 860.41K Increased by +50.36% | Sep 30, 23 |
| 19 | Millennium Management LLC | 1.66M (1.02%) | 1.29M Increased by +77.63% | Jun 30, 24 |
| 20 | Deerfield Management Co | 1.55M (0.96%) | 1.55M Increased by +100.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Invesco Emerging Markets Equity | 2.96M (1.83%) | 929.05K Increased by +31.34% | Dec 31, 24 |
| 2 | Fidelity Select Health Care | 2.80M (1.73%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 3 | Invesco Developing Markets A | 2.70M (1.67%) | -266.36K Decreased by -9.87% | Feb 28, 25 |
| 4 | Fidelity Growth Compy Commingled Pl S | 2.45M (1.51%) | 15.11K Increased by +0.62% | Sep 30, 24 |
| 5 | Fidelity Growth Compy Commingled Pl O | 2.43M (1.50%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 6 | T. Rowe Price Growth Stock | 2.32M (1.43%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | T. Rowe Price US Growth Stock Composite | 2.32M (1.43%) | -77.22K Decreased by -3.33% | Sep 30, 24 |
| 8 | T. Rowe Price U.S. Growth Stock SMA | 2.07M (1.28%) | 2.07M Increased by +100.00% | Dec 31, 23 |
| 9 | Fidelity® Growth Company | 1.82M (1.12%) | 62.20K Increased by +3.42% | Nov 30, 23 |
| 10 | Fidelity Growth Company Fund | 1.76M (1.09%) | -3.75K Decreased by -0.21% | Sep 30, 24 |
| 11 | Fidelity Advisor Health Care I | 1.67M (1.03%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 12 | MFS Mid Cap Growth Equity | 1.58M (0.97%) | 15.32K Increased by +0.97% | Dec 31, 24 |
| 13 | MFS Mid Cap Growth A | 1.56M (0.96%) | -10.13K Decreased by -0.65% | Feb 28, 25 |
| 14 | T. Rowe Price US Large-Cap Growth Equity | 1.48M (0.91%) | -8.75K Decreased by -0.59% | Dec 31, 24 |
| 15 | T. Rowe Price Lrg Cp Gr I | 1.47M (0.91%) | -1.24K Decreased by -0.08% | Feb 28, 25 |
| 16 | Vanguard Health Care Inv | 1.44M (0.89%) | -97.46K Decreased by -6.78% | Dec 31, 24 |
| 17 | T. Rowe Price Growth Stock Tr-B | 1.41M (0.87%) | -10.57K Decreased by -0.75% | Sep 30, 24 |
| 18 | Strategic Advisers Fidelity US TtlStk | 1.28M (0.79%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 19 | American Funds SMALLCAP World A | 1.27M (0.78%) | -60.57K Decreased by -4.78% | Dec 31, 24 |
| 20 | Polar Capital Healthcare Opports Inc | 1.07M (0.66%) | -175.82K Decreased by -16.43% | Nov 30, 23 |