| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. | 6.70M (16.08%) | -167.88K Decreased by -2.50% | Mar 31, 25 |
| 2 | venBio Select Advisor LLC | 6.46M (15.50%) | 1.31M Increased by +20.28% | Mar 31, 25 |
| 3 | Wellington Management Company LLP | 6.00M (14.39%) | 689.55K Increased by +11.50% | Mar 31, 25 |
| 4 | Baker Bros Advisors LP | 6.00M (14.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 5.23M (12.55%) | 344.08K Increased by +6.58% | Mar 31, 25 |
| 6 | Bvf Inc | 5.16M (12.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | FMR Inc | 4.41M (10.58%) | -421.19K Decreased by -9.55% | Mar 31, 25 |
| 8 | BlackRock Inc | 4.28M (10.28%) | -73.40K Decreased by -1.71% | Mar 31, 25 |
| 9 | Siren, L.L.C. | 3.24M (7.78%) | 270.58K Increased by +8.35% | Mar 31, 25 |
| 10 | Artal Group S A | 3.01M (7.21%) | -21.52K Decreased by -0.72% | Jun 30, 24 |
| 11 | State Street Corporation | 2.67M (6.41%) | 778.24K Increased by +29.12% | Mar 31, 24 |
| 12 | State Street Corp | 1.76M (4.22%) | 71.92K Increased by +4.08% | Mar 31, 25 |
| 13 | T. Rowe Price Investment Management,Inc. | 1.30M (3.11%) | -314.55K Decreased by -24.27% | Dec 31, 23 |
| 14 | Driehaus Capital Management LLC | 1.17M (2.80%) | -221.58K Decreased by -18.96% | Mar 31, 25 |
| 15 | Geode Capital Management, LLC | 1.13M (2.72%) | 28.28K Increased by +2.49% | Mar 31, 25 |
| 16 | Redmile Group, LLC | 983.41K (2.36%) | -117.02K Decreased by -11.90% | Mar 31, 25 |
| 17 | UBS Asset Mgmt Americas Inc | 896.40K (2.15%) | 491.74K Increased by +54.86% | Mar 31, 25 |
| 18 | Aquilo Capital Management, LLC | 881.34K (2.11%) | 99.12K Increased by +11.25% | Dec 31, 23 |
| 19 | Rock Springs Capital Management LP | 794.44K (1.91%) | -239.70K Decreased by -30.17% | Mar 31, 25 |
| 20 | Merck & Co Inc | 772.16K (1.85%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price New Horizons | 3.05M (7.32%) | -41.27K Decreased by -1.35% | Mar 31, 25 |
| 2 | US Small-Cap Growth II Equity Comp | 3.05M (7.32%) | -42.16K Decreased by -1.38% | Mar 31, 25 |
| 3 | Vanguard Health Care Inv | 3.01M (7.23%) | 662.16K Increased by +21.97% | Mar 31, 25 |
| 4 | Fidelity Growth Compy Commingled Pl O | 2.24M (5.37%) | 52.60K Increased by +2.35% | Aug 31, 24 |
| 5 | Fidelity Growth Compy Commingled Pl S | 2.07M (4.96%) | 119.60K Increased by +5.79% | Apr 30, 25 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 1.79M (4.28%) | 2.16K Increased by +0.12% | May 31, 25 |
| 7 | Vanguard US Total Market Shares ETF | 1.54M (3.71%) | 1.91K Increased by +0.12% | Sep 30, 24 |
| 8 | Fidelity Growth Company Fund | 1.44M (3.44%) | 86.70K Increased by +6.04% | Apr 30, 25 |
| 9 | Vanguard Small Cap Index | 1.39M (3.34%) | 5.13K Increased by +0.37% | May 31, 25 |
| 10 | T. Rowe Price Health Sciences | 1.21M (2.90%) | 19.81K Increased by +1.64% | Mar 31, 25 |
| 11 | iShares Russell 2000 ETF | 1.18M (2.82%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Vanguard Explorer Inv | 977.90K (2.35%) | -58.92K Decreased by -6.03% | Mar 31, 25 |
| 13 | T. Rowe Price New Horizons Tr-A | 872.24K (2.09%) | 65.62K Increased by +7.52% | Mar 31, 25 |
| 14 | T. Rowe Price New Horizons Tr-Z | 872.24K (2.09%) | 65.62K Increased by +7.52% | Mar 31, 25 |
| 15 | Vanguard Small Cap Growth Index Inv | 763.26K (1.83%) | -8.15K Decreased by -1.07% | May 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 720.13K (1.73%) | 5.43K Increased by +0.75% | May 31, 25 |
| 17 | SPDR® S&P Biotech ETF | 678.65K (1.63%) | 4.02K Increased by +0.59% | May 31, 25 |
| 18 | T. Rowe Price Integrated US Sm Gr Eq | 570.77K (1.37%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | T. Rowe Price Integrated US SmCapGrEq | 570.77K (1.37%) | -570.77K Decreased by -100.00% | Mar 31, 25 |
| 20 | Fidelity® Select Biotechnology | 532.31K (1.28%) | -193.90K Decreased by -36.43% | Nov 30, 23 |