| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. | 6.86M (14.45%) | 156.75K Increased by +2.29% | Jun 30, 25 |
| 2 | Baker Bros Advisors LP | 6.65M (14.01%) | 655.50K Increased by +9.86% | Jun 30, 25 |
| 3 | venBio Select Advisor LLC | 6.56M (13.81%) | 95.56K Increased by +1.46% | Jun 30, 25 |
| 4 | Vanguard Group Inc | 5.62M (11.84%) | 388.46K Increased by +6.91% | Jun 30, 25 |
| 5 | Bvf Inc | 5.50M (11.59%) | 340.91K Increased by +6.20% | Jun 30, 25 |
| 6 | FMR Inc | 5.43M (11.44%) | 1.02M Increased by +18.83% | Jun 30, 25 |
| 7 | Wellington Management Company LLP | 5.37M (11.32%) | -624.81K Decreased by -11.63% | Jun 30, 25 |
| 8 | BlackRock Inc | 4.15M (8.74%) | -134.64K Decreased by -3.25% | Jun 30, 25 |
| 9 | Siren, L.L.C. | 3.43M (7.22%) | 187.84K Increased by +5.48% | Jun 30, 25 |
| 10 | Artal Group S A | 3.01M (6.33%) | -21.52K Decreased by -0.72% | Jun 30, 24 |
| 11 | State Street Corporation | 2.67M (5.63%) | 778.24K Increased by +29.12% | Mar 31, 24 |
| 12 | State Street Corp | 1.55M (3.27%) | -206.28K Decreased by -13.27% | Jun 30, 25 |
| 13 | T. Rowe Price Investment Management,Inc. | 1.30M (2.73%) | -314.55K Decreased by -24.27% | Dec 31, 23 |
| 14 | Capital Research Global Investors | 1.26M (2.66%) | 896.99K Increased by +71.07% | Jun 30, 25 |
| 15 | Geode Capital Management, LLC | 1.19M (2.51%) | 59.35K Increased by +4.97% | Jun 30, 25 |
| 16 | Driehaus Capital Management LLC | 933.89K (1.97%) | -234.90K Decreased by -25.15% | Jun 30, 25 |
| 17 | Aquilo Capital Management, LLC | 881.34K (1.86%) | 99.12K Increased by +11.25% | Dec 31, 23 |
| 18 | Jennison Associates LLC | 825.02K (1.74%) | 272.74K Increased by +33.06% | Jun 30, 25 |
| 19 | UBS Asset Mgmt Americas Inc | 818.93K (1.73%) | -77.48K Decreased by -9.46% | Jun 30, 25 |
| 20 | Redmile Group, LLC | 803.29K (1.69%) | -180.12K Decreased by -22.42% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | US Small-Cap Growth II Equity Comp | 2.90M (6.11%) | -150.42K Decreased by -5.18% | Jun 30, 25 |
| 2 | T. Rowe Price New Horizons | 2.67M (5.61%) | -236.19K Decreased by -8.86% | Jul 31, 25 |
| 3 | Vanguard Health Care Inv | 2.39M (5.03%) | -626.58K Decreased by -26.25% | Jun 30, 25 |
| 4 | Fidelity Growth Compy Commingled Pl S | 2.36M (4.96%) | 14.03K Increased by +0.60% | Jul 31, 25 |
| 5 | Fidelity Growth Compy Commingled Pl O | 2.24M (4.71%) | 52.60K Increased by +2.35% | Aug 31, 24 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 1.88M (3.96%) | -39.75K Decreased by -2.12% | Jul 31, 25 |
| 7 | Fidelity Growth Company Fund | 1.64M (3.46%) | -2.90K Decreased by -0.18% | Jul 31, 25 |
| 8 | Vanguard US Total Market Shares ETF | 1.54M (3.25%) | 1.91K Increased by +0.12% | Sep 30, 24 |
| 9 | Vanguard Small Cap Index | 1.45M (3.05%) | -9.73K Decreased by -0.67% | Jul 31, 25 |
| 10 | T. Rowe Price Health Sciences | 1.20M (2.54%) | -161.06K Decreased by -13.37% | Jul 31, 25 |
| 11 | iShares Russell 2000 ETF | 1.13M (2.38%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 12 | American Funds SMALLCAP World A | 1.11M (2.34%) | 794.64K Increased by +71.44% | Jun 30, 25 |
| 13 | Vanguard Explorer Inv | 977.90K (2.06%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 14 | T. Rowe Price New Horizons Tr-A | 931.72K (1.96%) | 59.49K Increased by +6.38% | Jun 30, 25 |
| 15 | T. Rowe Price New Horizons Tr-Z | 872.24K (1.84%) | 65.62K Increased by +7.52% | Mar 31, 25 |
| 16 | Vanguard Small Cap Growth Index Inv | 818.18K (1.72%) | -321.00 Decreased by -0.04% | Jul 31, 25 |
| 17 | T. Rowe Price Integrated US SmCapGrEq | 570.77K (1.20%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Eventide Healthcare & Life Sciences I | 562.99K (1.19%) | 37.85K Increased by +6.72% | Jun 30, 25 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 557.69K (1.17%) | -244.86K Decreased by -43.91% | Jul 31, 25 |
| 20 | T. Rowe Price Integrated US Sm Gr Eq | 535.97K (1.13%) | -34.80K Decreased by -6.49% | Jul 31, 25 |