| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. | 6.65M (15.56%) | 254.82K Increased by +3.83% | Sep 30, 24 |
| 2 | Baker Bros Advisors LP | 6.00M (14.04%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Wellington Management Company LLP | 5.31M (12.43%) | 688.97K Increased by +12.98% | Dec 31, 24 |
| 4 | Bvf Inc | 5.16M (12.09%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | venBio Select Advisor LLC | 5.15M (12.06%) | 650.00K Increased by +12.62% | Dec 31, 24 |
| 6 | FMR Inc | 5.11M (11.97%) | 282.30K Increased by +5.53% | Sep 30, 24 |
| 7 | Vanguard Group Inc | 4.89M (11.45%) | 133.55K Increased by +2.73% | Dec 31, 24 |
| 8 | BlackRock Inc | 4.21M (9.86%) | 56.22K Increased by +1.33% | Sep 30, 24 |
| 9 | Artal Group S A | 3.01M (7.04%) | -21.52K Decreased by -0.72% | Jun 30, 24 |
| 10 | Siren, L.L.C. | 2.97M (6.96%) | 2.97M Increased by +100.00% | Sep 30, 24 |
| 11 | State Street Corporation | 2.67M (6.26%) | 778.24K Increased by +29.12% | Mar 31, 24 |
| 12 | State Street Corp | 1.73M (4.05%) | -182.55K Decreased by -10.56% | Sep 30, 24 |
| 13 | Redmile Group, LLC | 1.39M (3.26%) | -186.02K Decreased by -13.35% | Sep 30, 24 |
| 14 | Driehaus Capital Management LLC | 1.33M (3.11%) | 1.11M Increased by +83.19% | Sep 30, 24 |
| 15 | T. Rowe Price Investment Management,Inc. | 1.30M (3.04%) | -314.55K Decreased by -24.27% | Dec 31, 23 |
| 16 | Geode Capital Management, LLC | 1.05M (2.47%) | -996.00 Decreased by -0.09% | Sep 30, 24 |
| 17 | Rock Springs Capital Management LP | 1.05M (2.46%) | -114.59K Decreased by -10.92% | Sep 30, 24 |
| 18 | Aquilo Capital Management, LLC | 881.34K (2.06%) | 99.12K Increased by +11.25% | Dec 31, 23 |
| 19 | Jennison Associates LLC | 716.93K (1.68%) | -80.75K Decreased by -11.26% | Dec 31, 24 |
| 20 | Deep Track Capital, LP | 600.33K (1.41%) | -899.67K Decreased by -149.86% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price New Horizons | 3.09M (7.25%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | US Small-Cap Growth II Equity Comp | 3.09M (7.25%) | -46.89K Decreased by -1.52% | Dec 31, 24 |
| 3 | Vanguard Health Care Inv | 2.35M (5.51%) | 525.72K Increased by +22.36% | Dec 31, 24 |
| 4 | Fidelity Growth Compy Commingled Pl S | 2.29M (5.36%) | 22.80K Increased by +1.00% | Dec 31, 24 |
| 5 | Fidelity Growth Compy Commingled Pl O | 2.24M (5.24%) | 52.60K Increased by +2.35% | Aug 31, 24 |
| 6 | Fidelity Growth Company Fund | 1.61M (3.78%) | -32.98K Decreased by -2.04% | Dec 31, 24 |
| 7 | Vanguard Total Stock Mkt Idx Inv | 1.53M (3.58%) | 2.50K Increased by +0.16% | Dec 31, 24 |
| 8 | T. Rowe Price Health Sciences | 1.37M (3.21%) | 124.68K Increased by +9.10% | Dec 31, 24 |
| 9 | iShares Russell 2000 ETF | 1.28M (2.99%) | -9.70K Decreased by -0.76% | Jan 31, 25 |
| 10 | Vanguard Small Cap Index | 1.24M (2.90%) | 19.68K Increased by +1.59% | Dec 31, 24 |
| 11 | T. Rowe Price Integrated US SmCapGrEq | 1.14M (2.67%) | 570.77K Increased by +50.00% | Dec 31, 24 |
| 12 | Vanguard Explorer Inv | 1.04M (2.43%) | 163.14K Increased by +15.73% | Dec 31, 24 |
| 13 | T. Rowe Price New Horizons Tr-Z | 806.61K (1.89%) | 60.00K Increased by +7.44% | Dec 31, 24 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 719.77K (1.69%) | 47.16K Increased by +6.55% | Dec 31, 24 |
| 15 | Vanguard Small Cap Growth Index Inv | 699.01K (1.64%) | 29.68K Increased by +4.25% | Dec 31, 24 |
| 16 | SPDR® S&P Biotech ETF | 605.79K (1.42%) | -13.74K Decreased by -2.27% | Jan 31, 25 |
| 17 | T. Rowe Price Integrated US Sm Gr Eq | 570.77K (1.34%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Fidelity® Select Biotechnology | 532.31K (1.25%) | -193.90K Decreased by -36.43% | Nov 30, 23 |
| 19 | Eventide Healthcare & Life Sciences I | 507.90K (1.19%) | 45.80K Increased by +9.02% | Sep 30, 24 |
| 20 | Fidelity Growth Company K6 | 486.83K (1.14%) | -10.52K Decreased by -2.16% | Dec 31, 24 |