| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. | 6.87M (16.05%) | 224.86K Increased by +3.27% | Dec 31, 24 |
| 2 | Baker Bros Advisors LP | 6.00M (14.00%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Wellington Management Company LLP | 5.31M (12.40%) | 688.97K Increased by +12.98% | Dec 31, 24 |
| 4 | Bvf Inc | 5.16M (12.06%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | venBio Select Advisor LLC | 5.15M (12.03%) | 650.00K Increased by +12.62% | Dec 31, 24 |
| 6 | Vanguard Group Inc | 4.89M (11.41%) | 133.55K Increased by +2.73% | Dec 31, 24 |
| 7 | FMR Inc | 4.83M (11.28%) | -278.72K Decreased by -5.77% | Dec 31, 24 |
| 8 | BlackRock Inc | 4.36M (10.17%) | 144.65K Increased by +3.32% | Dec 31, 24 |
| 9 | Artal Group S A | 3.01M (7.02%) | -21.52K Decreased by -0.72% | Jun 30, 24 |
| 10 | Siren, L.L.C. | 2.97M (6.94%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | State Street Corporation | 2.67M (6.24%) | 778.24K Increased by +29.12% | Mar 31, 24 |
| 12 | State Street Corp | 1.69M (3.94%) | -39.35K Decreased by -2.33% | Dec 31, 24 |
| 13 | Driehaus Capital Management LLC | 1.39M (3.25%) | 61.67K Increased by +4.44% | Dec 31, 24 |
| 14 | T. Rowe Price Investment Management,Inc. | 1.30M (3.03%) | -314.55K Decreased by -24.27% | Dec 31, 23 |
| 15 | Geode Capital Management, LLC | 1.11M (2.58%) | 52.26K Increased by +4.73% | Dec 31, 24 |
| 16 | Redmile Group, LLC | 1.10M (2.57%) | -292.82K Decreased by -26.61% | Dec 31, 24 |
| 17 | Rock Springs Capital Management LP | 1.03M (2.42%) | -15.25K Decreased by -1.47% | Dec 31, 24 |
| 18 | Aquilo Capital Management, LLC | 881.34K (2.06%) | 99.12K Increased by +11.25% | Dec 31, 23 |
| 19 | Merck & Co Inc | 772.16K (1.80%) | 772.16K Increased by +100.00% | Dec 31, 24 |
| 20 | Jennison Associates LLC | 716.93K (1.67%) | -80.75K Decreased by -11.26% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | US Small-Cap Growth II Equity Comp | 3.09M (7.23%) | -46.89K Decreased by -1.52% | Dec 31, 24 |
| 2 | T. Rowe Price New Horizons | 3.09M (7.22%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 3 | Vanguard Health Care Inv | 2.35M (5.49%) | 525.72K Increased by +22.36% | Dec 31, 24 |
| 4 | Fidelity Growth Compy Commingled Pl O | 2.24M (5.22%) | 52.60K Increased by +2.35% | Aug 31, 24 |
| 5 | Fidelity Growth Compy Commingled Pl S | 1.93M (4.50%) | -250.03K Decreased by -12.97% | Feb 28, 25 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 1.54M (3.59%) | 1.66K Increased by +0.11% | Feb 28, 25 |
| 7 | Fidelity Growth Company Fund | 1.35M (3.14%) | -196.90K Decreased by -14.63% | Feb 28, 25 |
| 8 | Vanguard Small Cap Index | 1.24M (2.90%) | 1.01K Increased by +0.08% | Feb 28, 25 |
| 9 | iShares Russell 2000 ETF | 1.24M (2.89%) | -10.72K Decreased by -0.87% | Mar 31, 25 |
| 10 | T. Rowe Price Health Sciences | 1.19M (2.78%) | -137.20K Decreased by -11.54% | Feb 28, 25 |
| 11 | T. Rowe Price Integrated US SmCapGrEq | 1.14M (2.67%) | 570.77K Increased by +50.00% | Dec 31, 24 |
| 12 | Vanguard Explorer Inv | 1.04M (2.42%) | 163.14K Increased by +15.73% | Dec 31, 24 |
| 13 | T. Rowe Price New Horizons Tr-Z | 806.61K (1.88%) | 60.00K Increased by +7.44% | Dec 31, 24 |
| 14 | SPDR® S&P Biotech ETF | 722.57K (1.69%) | -7.75K Decreased by -1.07% | Mar 31, 25 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 721.06K (1.68%) | 1.08K Increased by +0.15% | Feb 28, 25 |
| 16 | Vanguard Small Cap Growth Index Inv | 695.75K (1.62%) | -5.85K Decreased by -0.84% | Feb 28, 25 |
| 17 | T. Rowe Price Integrated US Sm Gr Eq | 570.77K (1.33%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 18 | Fidelity® Select Biotechnology | 532.31K (1.24%) | -193.90K Decreased by -36.43% | Nov 30, 23 |
| 19 | UBS: US Equity Small Cap Growth | 483.23K (1.13%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | Fidelity Growth Company K6 | 468.93K (1.10%) | -17.91K Decreased by -3.82% | Jan 31, 25 |