| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. | 6.86M (14.61%) | 156.75K Increased by +2.29% | Jun 30, 25 |
| 2 | Baker Bros Advisors LP | 6.65M (14.16%) | 655.50K Increased by +9.86% | Jun 30, 25 |
| 3 | venBio Select Advisor LLC | 6.56M (13.96%) | 95.56K Increased by +1.46% | Jun 30, 25 |
| 4 | Vanguard Group Inc | 5.62M (11.97%) | 388.46K Increased by +6.91% | Jun 30, 25 |
| 5 | Bvf Inc | 5.50M (11.72%) | 340.91K Increased by +6.20% | Jun 30, 25 |
| 6 | FMR Inc | 5.43M (11.57%) | 1.02M Increased by +18.83% | Jun 30, 25 |
| 7 | Wellington Management Company LLP | 5.37M (11.44%) | -624.81K Decreased by -11.63% | Jun 30, 25 |
| 8 | BlackRock Inc | 4.28M (9.12%) | -73.40K Decreased by -1.71% | Mar 31, 25 |
| 9 | Siren, L.L.C. | 3.43M (7.30%) | 187.84K Increased by +5.48% | Jun 30, 25 |
| 10 | Artal Group S A | 3.01M (6.40%) | -21.52K Decreased by -0.72% | Jun 30, 24 |
| 11 | State Street Corporation | 2.67M (5.69%) | 778.24K Increased by +29.12% | Mar 31, 24 |
| 12 | State Street Corp | 1.76M (3.75%) | 71.92K Increased by +4.08% | Mar 31, 25 |
| 13 | T. Rowe Price Investment Management,Inc. | 1.30M (2.76%) | -314.55K Decreased by -24.27% | Dec 31, 23 |
| 14 | Capital Research Global Investors | 1.26M (2.69%) | 896.99K Increased by +71.07% | Jun 30, 25 |
| 15 | Driehaus Capital Management LLC | 1.17M (2.49%) | -221.58K Decreased by -18.96% | Mar 31, 25 |
| 16 | Geode Capital Management, LLC | 1.13M (2.41%) | 28.28K Increased by +2.49% | Mar 31, 25 |
| 17 | Aquilo Capital Management, LLC | 881.34K (1.88%) | 99.12K Increased by +11.25% | Dec 31, 23 |
| 18 | Jennison Associates LLC | 825.02K (1.76%) | 272.74K Increased by +33.06% | Jun 30, 25 |
| 19 | UBS Asset Mgmt Americas Inc | 818.93K (1.74%) | -77.48K Decreased by -9.46% | Jun 30, 25 |
| 20 | Redmile Group, LLC | 803.29K (1.71%) | -180.12K Decreased by -22.42% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price New Horizons | 2.90M (6.18%) | 131.16K Increased by +4.52% | Jun 30, 25 |
| 2 | US Small-Cap Growth II Equity Comp | 2.90M (6.18%) | -150.42K Decreased by -5.18% | Jun 30, 25 |
| 3 | Vanguard Health Care Inv | 2.39M (5.08%) | -626.58K Decreased by -26.25% | Jun 30, 25 |
| 4 | Fidelity Growth Compy Commingled Pl S | 2.36M (5.02%) | 14.03K Increased by +0.60% | Jul 31, 25 |
| 5 | Fidelity Growth Compy Commingled Pl O | 2.24M (4.76%) | 52.60K Increased by +2.35% | Aug 31, 24 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 1.88M (4.00%) | -39.75K Decreased by -2.12% | Jul 31, 25 |
| 7 | Fidelity Growth Company Fund | 1.64M (3.49%) | -2.90K Decreased by -0.18% | Jul 31, 25 |
| 8 | Vanguard US Total Market Shares ETF | 1.54M (3.29%) | 1.91K Increased by +0.12% | Sep 30, 24 |
| 9 | Vanguard Small Cap Index | 1.45M (3.09%) | -9.73K Decreased by -0.67% | Jul 31, 25 |
| 10 | T. Rowe Price Health Sciences | 1.37M (2.91%) | 190.87K Increased by +13.97% | Jun 30, 25 |
| 11 | iShares Russell 2000 ETF | 1.13M (2.40%) | -12.60K Decreased by -1.12% | Aug 29, 25 |
| 12 | American Funds SMALLCAP World A | 1.11M (2.37%) | 794.64K Increased by +71.44% | Jun 30, 25 |
| 13 | Vanguard Explorer Inv | 977.90K (2.08%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 14 | T. Rowe Price New Horizons Tr-A | 931.72K (1.98%) | 59.49K Increased by +6.38% | Jun 30, 25 |
| 15 | T. Rowe Price New Horizons Tr-Z | 872.24K (1.86%) | 65.62K Increased by +7.52% | Mar 31, 25 |
| 16 | Vanguard Small Cap Growth Index Inv | 818.18K (1.74%) | -321.00 Decreased by -0.04% | Jul 31, 25 |
| 17 | T. Rowe Price Integrated US Sm Gr Eq | 570.77K (1.22%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | T. Rowe Price Integrated US SmCapGrEq | 570.77K (1.22%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Eventide Healthcare & Life Sciences I | 562.99K (1.20%) | 37.85K Increased by +6.72% | Jun 30, 25 |
| 20 | Vanguard Institutional Extnd Mkt Idx Tr | 557.69K (1.19%) | -244.86K Decreased by -43.91% | Jul 31, 25 |