| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 4.35M (18.61%) | 8.18K Increased by +0.19% | Dec 31, 25 |
| 2 | BlackRock Inc | 3.94M (16.85%) | 103.69K Increased by +2.63% | Dec 31, 25 |
| 3 | venBio Select Advisor LLC | 2.89M (12.36%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Vanguard Group Inc | 2.78M (11.89%) | -13.36K Decreased by -0.48% | Dec 31, 25 |
| 5 | State Street Corp | 1.34M (5.74%) | -53.66K Decreased by -4.00% | Dec 31, 25 |
| 6 | State Street Corporation | 944.55K (4.04%) | -292.95K Decreased by -31.01% | Mar 31, 24 |
| 7 | Soleus Capital Management, L.P. | 941.06K (4.03%) | -77.77K Decreased by -8.26% | Dec 31, 25 |
| 8 | Capital World Investors | 824.72K (3.53%) | 15.22K Increased by +1.85% | Mar 31, 26 |
| 9 | BRAIDWELL LP | 727.81K (3.11%) | 327.07K Increased by +44.94% | Jun 30, 25 |
| 10 | Point72 Asset Management, L.P. | 698.16K (2.99%) | 138.90K Increased by +19.89% | Sep 30, 23 |
| 11 | Redmile Group, LLC | 673.50K (2.88%) | -4.20K Decreased by -0.62% | Mar 31, 26 |
| 12 | Hood River Capital Management LLC | 613.30K (2.62%) | 6.36K Increased by +1.04% | Dec 31, 25 |
| 13 | Geode Capital Management, LLC | 611.88K (2.62%) | 634.00 Increased by +0.10% | Dec 31, 25 |
| 14 | Goldman Sachs Group Inc | 530.36K (2.27%) | 296.72K Increased by +55.95% | Jun 30, 25 |
| 15 | T. Rowe Price Associates, Inc. | 529.96K (2.27%) | 62.90K Increased by +11.87% | Dec 31, 25 |
| 16 | Frazier Life Sciences Management, L.P. | 488.46K (2.09%) | -200.00K Decreased by -40.95% | Dec 31, 25 |
| 17 | Dimensional Fund Advisors, Inc. | 468.99K (2.01%) | -23.98K Decreased by -5.11% | Mar 31, 26 |
| 18 | Bellevue Group AG | 410.32K (1.76%) | 409.01K Increased by +99.68% | Dec 31, 25 |
| 19 | Citadel Advisors Llc | 386.50K (1.65%) | -250.48K Decreased by -64.81% | Dec 31, 25 |
| 20 | William Blair Investment Management, LLC | 376.34K (1.61%) | 227.04K Increased by +60.33% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Select Biotechnology | 1.99M (8.49%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 2 | Fidelity Select Biotechnology | 1.81M (7.73%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | iShares Core S&P Small-Cap ETF | 1.57M (6.73%) | 327.00 Increased by +0.02% | Apr 30, 26 |
| 4 | Fidelity Growth Compy Commingled Pl S | 1.05M (4.49%) | 5.40K Increased by +0.52% | Mar 31, 26 |
| 5 | Fidelity Growth Compy Commingled Pl O | 915.43K (3.92%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 830.91K (3.56%) | 4.46K Increased by +0.54% | Mar 31, 26 |
| 7 | Vanguard US Total Market Shares ETF | 824.72K (3.53%) | 704.00 Increased by +0.09% | Sep 30, 24 |
| 8 | Fidelity Growth Company Fund | 785.52K (3.36%) | 10.00K Increased by +1.27% | Mar 31, 26 |
| 9 | American Funds SMALLCAP World A | 752.24K (3.22%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 10 | Vanguard Small Cap Index | 607.37K (2.60%) | 14.64K Increased by +2.41% | Mar 31, 26 |
| 11 | iShares Russell 2000 ETF | 583.03K (2.49%) | 4.93K Increased by +0.85% | Apr 30, 26 |
| 12 | SPDR® S&P Biotech ETF | 423.10K (1.81%) | 945.00 Increased by +0.22% | Aug 31, 25 |
| 13 | State Street® SPDR® S&P® Biotech ETF | 371.39K (1.59%) | -2.65K Decreased by -0.71% | Apr 30, 26 |
| 14 | Vanguard Small Cap Growth Index Inv | 340.06K (1.46%) | 10.91K Increased by +3.21% | Mar 31, 26 |
| 15 | Hood River Small-Cap Growth Instl | 329.78K (1.41%) | 256.42K Increased by +77.75% | Dec 31, 25 |
| 16 | First Trust NYSE Arca Biotech ETF | 290.50K (1.24%) | -1.35K Decreased by -0.47% | Apr 30, 26 |
| 17 | CS (Lux) Digital Health Equity SB USD | 290.00K (1.24%) | -40.00K Decreased by -13.79% | Mar 31, 24 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 288.38K (1.23%) | 7.13K Increased by +2.47% | Mar 31, 26 |
| 19 | T. Rowe Price Health Sciences | 281.65K (1.21%) | -13.90K Decreased by -4.94% | Mar 31, 26 |
| 20 | Fidelity Small Cap Index | 242.57K (1.04%) | 2.62K Increased by +1.08% | Feb 28, 26 |