| Rank | Holder | SharesFloat % | Change | Date reported | 
|---|---|---|---|---|
| 1 | Capital Research & Mgmt Co - Division 3 | 4.23M (11.66%) | 236.49K  Increased by +5.59% | Dec 31, 23 | 
| 2 | Vanguard Group Inc | 3.20M (8.83%) | 105.69K  Increased by +3.30% | Sep 30, 23 | 
| 3 | FMR Inc | 2.87M (7.90%) | -2.78M  Decreased by -97.15% | Dec 31, 23 | 
| 4 | T. Rowe Price Investment Management,Inc. | 2.71M (7.47%) | -32.83K  Decreased by -1.21% | Dec 31, 23 | 
| 5 | BlackRock Inc | 2.02M (5.56%) | 52.46K  Increased by +2.60% | Dec 31, 23 | 
| 6 | T. Rowe Price Associates, Inc. | 1.96M (5.41%) | -773.25K  Decreased by -39.42% | Dec 31, 23 | 
| 7 | Sofinnova Ventures | 1.38M (3.81%) | 0.00  Increased by 0.00% | Dec 31, 23 | 
| 8 | Wellington Management Company LLP | 1.13M (3.13%) | -151.46K  Decreased by -13.36% | Dec 31, 23 | 
| 9 | Viking Global Investors LP | 1.13M (3.12%) | 183.31K  Increased by +16.20% | Sep 30, 23 | 
| 10 | General Atlantic Llc | 986.71K (2.72%) | 0.00  Increased by 0.00% | Dec 31, 23 | 
| 11 | State Street Corporation | 974.64K (2.69%) | 45.67K  Increased by +4.69% | Dec 31, 23 | 
| 12 | Pivotal bioVenture Partners Investment Advisor LLC | 797.01K (2.20%) | 0.00  Increased by 0.00% | Dec 31, 23 | 
| 13 | Geode Capital Management, LLC | 569.72K (1.57%) | 24.65K  Increased by +4.33% | Dec 31, 23 | 
| 14 | Farallon Capital Management, L.L.C. | 522.00K (1.44%) | 519.80K  Increased by +99.58% | Dec 31, 23 | 
| 15 | Rock Springs Capital Management LP | 515.02K (1.42%) | 9.59K  Increased by +1.86% | Dec 31, 23 | 
| 16 | UBS Group AG | 422.18K (1.16%) | 419.22K  Increased by +99.30% | Dec 31, 23 | 
| 17 | Goldman Sachs Group Inc | 402.54K (1.11%) | 367.27K  Increased by +91.24% | Dec 31, 23 | 
| 18 | AllianceBernstein L.P. | 363.37K (1.00%) | -20.59K  Decreased by -5.67% | Sep 30, 23 | 
| 19 | Woodline Partners LP | 357.47K (0.99%) | 334.75K  Increased by +93.64% | Dec 31, 23 | 
| 20 | Point72 Asset Management, L.P. | 347.80K (0.96%) | 301.86K  Increased by +86.79% | Sep 30, 23 | 
| Rank | Holder | SharesFloat % | Change | Date reported | 
|---|---|---|---|---|
| 1 | American Funds Growth Fund of Amer A | 2.07M (5.71%) | -353.12K  Decreased by -17.04% | Dec 31, 23 | 
| 2 | Capital Group Growth Fnd of Amer Comp | 2.07M (5.71%) | -353.12K  Decreased by -17.04% | Dec 31, 23 | 
| 3 | Fidelity® Growth Company | 1.26M (3.49%) | 0.00  Increased by 0.00% | Nov 30, 23 | 
| 4 | Fidelity Growth Compy Commingled Pl O | 1.20M (3.30%) | -421.36K  Decreased by -35.26% | Dec 31, 23 | 
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.02M (2.80%) | -2.50K  Decreased by -0.25% | Feb 29, 24 | 
| 6 | Vanguard Small Cap Index | 826.61K (2.28%) | 7.65K  Increased by +0.93% | Feb 29, 24 | 
| 7 | Fidelity Growth Company Fund | 825.58K (2.28%) | -438.53K  Decreased by -53.12% | Dec 31, 23 | 
| 8 | Vanguard Health Care Inv | 796.33K (2.20%) | -103.78K  Decreased by -13.03% | Dec 31, 23 | 
| 9 | American Funds New Perspective A | 681.81K (1.88%) | 306.36K  Increased by +44.93% | Dec 31, 23 | 
| 10 | Capital Group New Perspective Comp | 681.81K (1.88%) | 306.36K  Increased by +44.93% | Dec 31, 23 | 
| 11 | T. Rowe Price Mid-Cap Growth | 648.50K (1.79%) | 23.35K  Increased by +3.60% | Dec 31, 23 | 
| 12 | T. Rowe Price US Mid-Cap Growth Equity | 648.50K (1.79%) | 23.35K  Increased by +3.60% | Dec 31, 23 | 
| 13 | American Funds IS® Growth 1 | 565.35K (1.56%) | 165.80K  Increased by +29.33% | Dec 31, 23 | 
| 14 | Capital Group Growth Composite | 565.35K (1.56%) | 165.80K  Increased by +29.33% | Dec 31, 23 | 
| 15 | Vanguard Small Cap Value Index Inv | 563.79K (1.55%) | 2.81K  Increased by +0.50% | Feb 29, 24 | 
| 16 | BlackRock Event Driven Equity Instl | 553.86K (1.53%) | 27.12K  Increased by +4.90% | Feb 29, 24 | 
| 17 | Vanguard Institutional Extnd Mkt Idx Tr | 529.77K (1.46%) | 1.39K  Increased by +0.26% | Feb 29, 24 | 
| 18 | T. Rowe Price Health Sciences | 471.72K (1.30%) | -270.48K  Decreased by -57.34% | Dec 31, 23 | 
| 19 | Fidelity Growth Company K6 | 465.79K (1.28%) | -8.87K  Decreased by -1.90% | Nov 30, 23 | 
| 20 | Fidelity® Growth Company K6 | 465.79K (1.28%) | -8.87K  Decreased by -1.90% | Nov 30, 23 |