| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | VR Adviser, LLC | 6.47M (16.96%) | -254.50K Decreased by -3.93% | Mar 31, 26 |
| 2 | Frazier Life Sciences Management, L.P. | 4.96M (12.99%) | -78.76K Decreased by -1.59% | Mar 31, 26 |
| 3 | Suvretta Capital Management, LLC | 4.77M (12.49%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | TANG CAPITAL MANAGEMENT LLC | 4.57M (11.98%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | BlackRock Inc | 3.80M (9.94%) | 41.75K Increased by +1.10% | Mar 31, 26 |
| 6 | SILVERARC CAPITAL MANAGEMENT, LLC | 2.88M (7.53%) | 449.29K Increased by +15.62% | Mar 31, 26 |
| 7 | Capital World Investors | 2.81M (7.36%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | Vanguard Group Inc | 2.51M (6.57%) | 7.90K Increased by +0.31% | Dec 31, 25 |
| 9 | Point72 Asset Management, L.P. | 2.14M (5.60%) | -146.83K Decreased by -6.87% | Mar 31, 26 |
| 10 | Tudor Investment Corp Et AL | 2.00M (5.24%) | 2.00M Increased by +100.00% | Sep 30, 25 |
| 11 | State Street Corp | 1.96M (5.12%) | 44.15K Increased by +2.26% | Mar 31, 26 |
| 12 | Millennium Management LLC | 1.91M (5.01%) | -984.52K Decreased by -51.49% | Mar 31, 26 |
| 13 | Vestal Point Capital LP | 1.85M (4.85%) | -40.00K Decreased by -2.16% | Mar 31, 26 |
| 14 | Parkman Healthcare Partners LLC | 1.84M (4.81%) | 67.00K Increased by +3.65% | Mar 31, 26 |
| 15 | Vanguard Capital Management, LLC | 1.83M (4.79%) | 1.83M Increased by +100.00% | Mar 31, 26 |
| 16 | Kynam Capital Management, LP | 1.82M (4.77%) | 10.00K Increased by +0.55% | Mar 31, 26 |
| 17 | Boxer Capital LLC | 1.59M (4.16%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 18 | Boxer Capital Management, LLC | 1.59M (4.16%) | 1.59M Increased by +100.00% | Dec 31, 24 |
| 19 | Woodline Partners LP | 1.51M (3.95%) | -411.17K Decreased by -27.23% | Mar 31, 26 |
| 20 | Octagon Capital Advisors LP | 1.45M (3.80%) | 176.67K Increased by +12.18% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 2.81M (7.36%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.35M (3.54%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 3 | Vanguard US Total Market Shares ETF | 1.20M (3.14%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 1.19M (3.12%) | -7.33K Decreased by -0.62% | May 31, 26 |
| 5 | APO Medical Opportunities R | 1.17M (3.05%) | 866.80K Increased by +74.33% | Jul 31, 25 |
| 6 | iShares Russell 2000 ETF | 914.71K (2.40%) | 8.48K Increased by +0.93% | May 29, 26 |
| 7 | MEDICAL BioHealth EUR Acc | 861.55K (2.26%) | -116.38K Decreased by -13.51% | Apr 30, 26 |
| 8 | apo Medical Opportunities R | 771.44K (2.02%) | -3.47K Decreased by -0.45% | Apr 30, 26 |
| 9 | International Biotechnology Ord | 746.05K (1.95%) | -425.70K Decreased by -57.06% | Feb 28, 26 |
| 10 | SPDR® S&P Biotech ETF | 571.42K (1.50%) | 1.27K Increased by +0.22% | Aug 31, 25 |
| 11 | AZ InvestEd Ivy Small Cap Growth E | 497.47K (1.30%) | 144.19K Increased by +28.98% | Apr 30, 26 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 442.25K (1.16%) | 2.52K Increased by +0.57% | Apr 30, 26 |
| 13 | Impax Small Cap Institutional | 400.00K (1.05%) | 400.00K Increased by +100.00% | Apr 30, 26 |
| 14 | Biotech Growth Ord | 382.40K (1.00%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 15 | Fidelity Small Cap Index | 375.92K (0.98%) | 212.00 Increased by +0.06% | Mar 31, 26 |
| 16 | SEB Läkemedelsfond | 351.31K (0.92%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 17 | Candriam Eqs L Biotech C USD Cap | 350.00K (0.92%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 18 | Principal SmallCap Growth I Instl | 321.05K (0.84%) | -370.00 Decreased by -0.12% | Apr 30, 26 |
| 19 | iShares Russell 2000 Growth ETF | 315.81K (0.83%) | -2.06K Decreased by -0.65% | May 29, 26 |
| 20 | iShares Russell 2000 Value ETF | 286.26K (0.75%) | -380.00 Decreased by -0.13% | May 30, 24 |