| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.37M (27.80%) | 1.20M Increased by +11.58% | Dec 31, 24 |
| 2 | FMR Inc | 8.67M (23.25%) | 845.27K Increased by +9.75% | Dec 31, 24 |
| 3 | HHG PLC | 3.56M (9.55%) | 1.04M Increased by +29.17% | Dec 31, 24 |
| 4 | Paradigm Biocapital Advisors LP | 3.52M (9.43%) | 1.12M Increased by +31.72% | Dec 31, 24 |
| 5 | Adage Capital Partners Gp LLC | 3.06M (8.21%) | 986.75K Increased by +32.23% | Dec 31, 24 |
| 6 | BlackRock Inc | 2.73M (7.31%) | 303.18K Increased by +11.12% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 2.14M (5.73%) | 288.40K Increased by +13.50% | Dec 31, 24 |
| 8 | Cormorant Asset Management, LLC | 2.10M (5.63%) | 1.05M Increased by +50.00% | Dec 31, 24 |
| 9 | Woodline Partners LP | 1.85M (4.97%) | 251.92K Increased by +13.60% | Dec 31, 24 |
| 10 | EcoR1 Capital, LLC | 1.47M (3.94%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | Citadel Advisors Llc | 1.36M (3.65%) | 351.11K Increased by +25.80% | Dec 31, 24 |
| 12 | State Street Corp | 1.27M (3.40%) | -93.23K Decreased by -7.35% | Dec 31, 24 |
| 13 | Lord, Abbett & Co LLC | 1.27M (3.40%) | 564.32K Increased by +44.51% | Dec 31, 24 |
| 14 | Logos Global Management LP | 1.25M (3.35%) | 250.00K Increased by +20.00% | Dec 31, 24 |
| 15 | T. Rowe Price Associates, Inc. | 1.11M (2.98%) | 950.56K Increased by +85.64% | Dec 31, 24 |
| 16 | Holocene Advisors, LP | 1.02M (2.72%) | 1.02M Increased by +100.00% | Dec 31, 24 |
| 17 | RTW INVESTMENTS, LLC | 1.00M (2.68%) | 1.00M Increased by +100.00% | Mar 31, 24 |
| 18 | Perceptive Advisors LLC | 817.89K (2.19%) | 817.89K Increased by +100.00% | Dec 31, 24 |
| 19 | Bank of America Corp | 794.76K (2.13%) | 731.96K Increased by +92.10% | Dec 31, 24 |
| 20 | Orbimed Advisors, LLC | 758.57K (2.03%) | -500.00K Decreased by -65.91% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 2.20M (5.89%) | 268.13K Increased by +12.20% | Feb 28, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 1.65M (4.43%) | 20.65K Increased by +1.25% | Aug 31, 24 |
| 3 | Fidelity Growth Company Fund | 1.57M (4.20%) | 181.58K Increased by +11.59% | Feb 28, 25 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.18M (3.18%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 5 | Vanguard US Total Market Shares ETF | 1.00M (2.69%) | 193.50K Increased by +19.32% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 827.22K (2.22%) | -7.15K Decreased by -0.86% | Mar 31, 25 |
| 7 | Fidelity® Growth Company | 746.62K (2.00%) | 21.70K Increased by +2.91% | Nov 30, 23 |
| 8 | Fidelity Select Health Care | 689.69K (1.85%) | 25.80K Increased by +3.74% | Feb 28, 25 |
| 9 | SPDR® S&P Biotech ETF | 683.14K (1.83%) | -13.70K Decreased by -2.01% | Mar 31, 25 |
| 10 | Fidelity Small Cap Growth | 655.64K (1.76%) | 2.70K Increased by +0.41% | Jan 31, 25 |
| 11 | Fidelity® Small Cap Growth | 653.62K (1.75%) | -794.00 Decreased by -0.12% | Oct 31, 23 |
| 12 | Janus Henderson Global Life Sciences | 539.05K (1.45%) | 110.31K Increased by +20.46% | Dec 31, 24 |
| 13 | Janus Henderson Global Life Sciences D | 531.43K (1.43%) | -7.62K Decreased by -1.43% | Jan 31, 25 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 492.89K (1.32%) | 718.00 Increased by +0.15% | Feb 28, 25 |
| 15 | Fidelity Series Small Cap Opps | 490.53K (1.32%) | -213.89K Decreased by -43.60% | Oct 31, 23 |
| 16 | Fidelity® Series Small Cap Opps | 490.53K (1.32%) | -213.89K Decreased by -43.60% | Oct 31, 23 |
| 17 | Fidelity Growth Company K6 | 484.00K (1.30%) | 47.62K Increased by +9.84% | Feb 28, 25 |
| 18 | Fidelity Advisor® Biotechnology I | 472.43K (1.27%) | -13.35K Decreased by -2.83% | Nov 30, 23 |
| 19 | T. Rowe Price New Horizons | 466.02K (1.25%) | 101.20K Increased by +21.72% | Mar 31, 25 |
| 20 | Fidelity Contrafund | 459.29K (1.23%) | 0.00 Increased by 0.00% | Jan 31, 25 |