| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 11.19M (30.19%) | 824.04K Increased by +7.36% | Mar 31, 25 |
| 2 | FMR Inc | 8.88M (23.97%) | 214.13K Increased by +2.41% | Mar 31, 25 |
| 3 | HHG PLC | 4.60M (12.41%) | 1.04M Increased by +22.52% | Mar 31, 25 |
| 4 | Adage Capital Partners Gp LLC | 3.65M (9.86%) | 592.82K Increased by +16.22% | Mar 31, 25 |
| 5 | Paradigm Biocapital Advisors LP | 3.33M (8.98%) | -186.08K Decreased by -5.59% | Mar 31, 25 |
| 6 | BlackRock Inc | 2.87M (7.75%) | 147.15K Increased by +5.12% | Mar 31, 25 |
| 7 | Vanguard Group Inc | 2.28M (6.15%) | 142.33K Increased by +6.25% | Mar 31, 25 |
| 8 | Cormorant Asset Management, LLC | 2.00M (5.40%) | -100.00K Decreased by -5.00% | Mar 31, 25 |
| 9 | Logos Global Management LP | 1.65M (4.45%) | 400.00K Increased by +24.24% | Mar 31, 25 |
| 10 | EcoR1 Capital, LLC | 1.47M (3.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Woodline Partners LP | 1.46M (3.93%) | -395.09K Decreased by -27.12% | Mar 31, 25 |
| 12 | T. Rowe Price Associates, Inc. | 1.39M (3.76%) | 282.85K Increased by +20.31% | Mar 31, 25 |
| 13 | State Street Corp | 1.37M (3.70%) | 103.55K Increased by +7.55% | Mar 31, 25 |
| 14 | Lord, Abbett & Co LLC | 1.27M (3.42%) | 564.32K Increased by +44.51% | Dec 31, 24 |
| 15 | Franklin Resources Inc | 1.19M (3.20%) | 689.19K Increased by +58.09% | Mar 31, 25 |
| 16 | Holocene Advisors, LP | 1.02M (2.74%) | 1.02M Increased by +100.00% | Dec 31, 24 |
| 17 | RTW INVESTMENTS, LLC | 1.00M (2.70%) | 1.00M Increased by +100.00% | Mar 31, 24 |
| 18 | Perceptive Advisors LLC | 970.41K (2.62%) | 152.52K Increased by +15.72% | Mar 31, 25 |
| 19 | Geode Capital Management, LLC | 780.91K (2.11%) | 65.95K Increased by +8.45% | Mar 31, 25 |
| 20 | Orbimed Advisors, LLC | 758.57K (2.05%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 2.20M (5.93%) | 1.47K Increased by +0.07% | May 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 1.65M (4.45%) | 20.65K Increased by +1.25% | Aug 31, 24 |
| 3 | Fidelity Growth Company Fund | 1.57M (4.24%) | 3.78K Increased by +0.24% | May 31, 25 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.34M (3.62%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 1.00M (2.70%) | 193.50K Increased by +19.32% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 979.64K (2.64%) | 6.81K Increased by +0.69% | Jun 30, 25 |
| 7 | Fidelity® Growth Company | 746.62K (2.01%) | 21.70K Increased by +2.91% | Nov 30, 23 |
| 8 | Fidelity Select Health Care | 699.39K (1.89%) | 0.00 Increased by 0.00% | May 31, 25 |
| 9 | Fidelity Small Cap Growth | 696.57K (1.88%) | 1.50K Increased by +0.22% | Apr 30, 25 |
| 10 | Fidelity® Small Cap Growth | 653.62K (1.76%) | -794.00 Decreased by -0.12% | Oct 31, 23 |
| 11 | T. Rowe Price New Horizons | 609.99K (1.65%) | 61.16K Increased by +10.03% | Jun 30, 25 |
| 12 | US Small-Cap Growth II Equity Comp | 609.99K (1.65%) | 143.97K Increased by +23.60% | Jun 30, 25 |
| 13 | SPDR® S&P Biotech ETF | 572.95K (1.55%) | -9.39K Decreased by -1.64% | Jun 30, 25 |
| 14 | Janus Henderson Global Life Sciences D | 534.84K (1.44%) | 7.68K Increased by +1.44% | Apr 30, 25 |
| 15 | Janus Henderson Global Life Sciences | 527.16K (1.42%) | -11.89K Decreased by -2.26% | Mar 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 509.83K (1.38%) | 3.84K Increased by +0.75% | May 31, 25 |
| 17 | Janus Henderson Triton D | 501.62K (1.35%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 18 | Janus Henderson US SMID Cap Growth | 501.62K (1.35%) | 182.28K Increased by +36.34% | Mar 31, 25 |
| 19 | Fidelity Series Small Cap Opps | 490.53K (1.32%) | -213.89K Decreased by -43.60% | Oct 31, 23 |
| 20 | Fidelity® Series Small Cap Opps | 490.53K (1.32%) | -213.89K Decreased by -43.60% | Oct 31, 23 |