| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 11.19M (24.86%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | FMR Inc | 8.89M (19.74%) | 4.67K Increased by +0.05% | Jun 30, 25 |
| 3 | HHG PLC | 4.46M (9.91%) | -137.76K Decreased by -3.09% | Jun 30, 25 |
| 4 | BlackRock Inc | 3.40M (7.56%) | 529.89K Increased by +15.57% | Jun 30, 25 |
| 5 | Paradigm Biocapital Advisors LP | 2.92M (6.49%) | -409.65K Decreased by -14.03% | Jun 30, 25 |
| 6 | Adage Capital Partners Gp LLC | 2.52M (5.61%) | -1.13M Decreased by -44.74% | Jun 30, 25 |
| 7 | Vanguard Group Inc | 2.19M (4.86%) | -89.23K Decreased by -4.08% | Jun 30, 25 |
| 8 | Point72 Asset Management, L.P. | 2.14M (4.76%) | 1.77M Increased by +82.43% | Jun 30, 25 |
| 9 | T. Rowe Price Associates, Inc. | 1.79M (3.98%) | 400.60K Increased by +22.34% | Jun 30, 25 |
| 10 | Cormorant Asset Management, LLC | 1.50M (3.33%) | -500.00K Decreased by -33.33% | Jun 30, 25 |
| 11 | EcoR1 Capital, LLC | 1.47M (3.26%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | State Street Corp | 1.39M (3.08%) | 16.61K Increased by +1.20% | Jun 30, 25 |
| 13 | Woodline Partners LP | 1.24M (2.76%) | -215.16K Decreased by -17.32% | Jun 30, 25 |
| 14 | Citadel Advisors Llc | 1.23M (2.73%) | 524.46K Increased by +42.60% | Jun 30, 25 |
| 15 | Orbimed Advisors, LLC | 1.21M (2.69%) | 451.73K Increased by +37.32% | Jun 30, 25 |
| 16 | Franklin Resources Inc | 1.07M (2.38%) | -117.28K Decreased by -10.97% | Jun 30, 25 |
| 17 | Holocene Advisors, LP | 1.02M (2.25%) | 1.02M Increased by +100.00% | Dec 31, 24 |
| 18 | Logos Global Management LP | 1.00M (2.22%) | -650.00K Decreased by -65.00% | Jun 30, 25 |
| 19 | RTW INVESTMENTS, LLC | 1.00M (2.22%) | 1.00M Increased by +100.00% | Mar 31, 24 |
| 20 | Perceptive Advisors LLC | 970.41K (2.16%) | 152.52K Increased by +15.72% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 2.20M (4.89%) | 2.89K Increased by +0.13% | Jul 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 1.65M (3.67%) | 20.65K Increased by +1.25% | Aug 31, 24 |
| 3 | Fidelity Growth Company Fund | 1.56M (3.47%) | -9.34K Decreased by -0.60% | Jul 31, 25 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.18M (2.61%) | -26.09K Decreased by -2.22% | Jul 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 1.00M (2.23%) | 193.50K Increased by +19.32% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 945.98K (2.10%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 7 | Fidelity® Growth Company | 746.62K (1.66%) | 21.70K Increased by +2.91% | Nov 30, 23 |
| 8 | Fidelity Select Health Care | 699.39K (1.55%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 9 | Fidelity Small Cap Growth | 696.57K (1.55%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Fidelity® Small Cap Growth | 653.62K (1.45%) | -794.00 Decreased by -0.12% | Oct 31, 23 |
| 11 | US Small-Cap Growth II Equity Comp | 609.99K (1.35%) | 143.97K Increased by +23.60% | Jun 30, 25 |
| 12 | SPDR® S&P Biotech ETF | 571.67K (1.27%) | 1.27K Increased by +0.22% | Aug 31, 25 |
| 13 | T. Rowe Price New Horizons | 538.34K (1.20%) | -71.65K Decreased by -13.31% | Jul 31, 25 |
| 14 | Janus Henderson Global Life Sciences | 517.85K (1.15%) | -9.31K Decreased by -1.80% | Jun 30, 25 |
| 15 | Janus Henderson Global Life Sciences D | 517.85K (1.15%) | -13.98K Decreased by -2.70% | Jun 30, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 511.82K (1.14%) | 1.99K Increased by +0.39% | Jun 30, 25 |
| 17 | Janus Henderson Triton D | 495.77K (1.10%) | -5.85K Decreased by -1.18% | Jun 30, 25 |
| 18 | Janus Henderson US SMID Cap Growth | 495.77K (1.10%) | -5.85K Decreased by -1.18% | Jun 30, 25 |
| 19 | Janus Henderson US SMID Cap Growth MA | 495.77K (1.10%) | 495.74K Increased by +99.99% | Jun 30, 25 |
| 20 | Fidelity Series Small Cap Opps | 490.53K (1.09%) | -213.89K Decreased by -43.60% | Oct 31, 23 |