| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Adage Capital Partners Gp LLC | 5.16M (14.40%) | -513.63K Decreased by -9.95% | Dec 31, 24 |
| 2 | Pivotal bioVenture Partners Investment Advisor LLC | 4.49M (12.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Sofinnova Ventures | 4.28M (11.94%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Affinity Asset Advisors, LLC | 3.97M (11.08%) | 1.15M Increased by +28.95% | Dec 31, 24 |
| 5 | Rock Springs Capital Management LP | 3.86M (10.78%) | 59.10K Increased by +1.53% | Dec 31, 24 |
| 6 | BlackRock Inc | 3.81M (10.64%) | 321.30K Increased by +8.43% | Dec 31, 24 |
| 7 | Samlyn Capital, LLC | 3.26M (9.09%) | -91.38K Decreased by -2.80% | Sep 30, 24 |
| 8 | Vanguard Group Inc | 2.63M (7.35%) | 8.91K Increased by +0.34% | Dec 31, 24 |
| 9 | NEA Management Company, LLC | 2.44M (6.80%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | Eventide Asset Management, LLC | 2.22M (6.19%) | -1.91M Decreased by -86.24% | Dec 31, 24 |
| 11 | Millennium Management LLC | 1.88M (5.25%) | 137.82K Increased by +7.32% | Dec 31, 24 |
| 12 | FMR Inc | 1.82M (5.09%) | -654.23K Decreased by -35.86% | Dec 31, 24 |
| 13 | Samsara BioCapital, LLC | 1.56M (4.36%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | Saturn V Capital Management LLC | 1.37M (3.84%) | 5.77K Increased by +0.42% | Dec 31, 24 |
| 15 | Octagon Capital Advisors LP | 1.30M (3.63%) | 1.25M Increased by +96.18% | Sep 30, 23 |
| 16 | CHI Advisors LLC | 1.27M (3.54%) | 75.00K Increased by +5.91% | Sep 30, 23 |
| 17 | Sphera Funds Management Ltd. | 1.19M (3.32%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 1.18M (3.29%) | 8.45K Increased by +0.72% | Dec 31, 24 |
| 19 | Blue Owl Capital Holdings LP | 1.08M (3.01%) | -40.00K Decreased by -3.70% | Dec 31, 24 |
| 20 | State Street Corp | 1.01M (2.81%) | -42.97K Decreased by -4.26% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Select Biotechnology | 2.27M (6.33%) | -198.00K Decreased by -8.73% | Nov 30, 23 |
| 2 | Eventide Healthcare & Life Sciences I | 2.22M (6.19%) | -1.91M Decreased by -86.24% | Dec 31, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.67M (4.65%) | 108.95K Increased by +6.54% | Feb 28, 25 |
| 4 | iShares Russell 2000 ETF | 1.36M (3.79%) | -11.77K Decreased by -0.87% | Mar 31, 25 |
| 5 | Fidelity Select Biotechnology | 1.17M (3.25%) | -311.00K Decreased by -26.69% | Feb 28, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 679.65K (1.90%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 7 | Fidelity Small Cap Index | 521.06K (1.45%) | -9.76K Decreased by -1.87% | Jan 31, 25 |
| 8 | iShares Russell 2000 Value ETF | 466.26K (1.30%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | abrdn Life Sciences Investors | 326.76K (0.91%) | 156.24K Increased by +47.81% | Feb 28, 25 |
| 10 | Fidelity® Small Cap Index | 321.38K (0.90%) | 6.80K Increased by +2.12% | Oct 31, 23 |
| 11 | State St Russell Sm/Mid Cp® Indx NL Cl C | 318.10K (0.89%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 12 | Kennedy Micro Cap | 280.86K (0.78%) | -6.52K Decreased by -2.32% | Mar 31, 24 |
| 13 | iShares Biotechnology ETF | 260.25K (0.73%) | -2.90K Decreased by -1.11% | Mar 31, 25 |
| 14 | Fidelity Extended Market Index | 259.46K (0.72%) | -1.65K Decreased by -0.64% | Feb 28, 25 |
| 15 | Vanguard Russell 2000 ETF | 235.83K (0.66%) | 5.59K Increased by +2.37% | Feb 28, 25 |
| 16 | Fidelity® Extended Market Index | 220.50K (0.62%) | 18.94K Increased by +8.59% | Nov 30, 23 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 175.30K (0.49%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 18 | NT R2000 Value Index Fund - NL | 125.70K (0.35%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 19 | NT R2000 Index Fund - NL | 124.35K (0.35%) | 100.00 Increased by +0.08% | Dec 31, 24 |
| 20 | Schwab Small Cap Index | 122.28K (0.34%) | 0.00 Increased by 0.00% | Feb 28, 25 |