| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 8.40M (15.30%) | -308.80K Decreased by -3.67% | Mar 31, 26 |
| 2 | Wellington Management Company LLP | 7.26M (13.22%) | 138.30K Increased by +1.90% | Mar 31, 26 |
| 3 | venBio Select Advisor LLC | 6.56M (11.94%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | HHG PLC | 5.35M (9.75%) | 264.83K Increased by +4.95% | Mar 31, 26 |
| 5 | Deep Track Capital, LP | 4.28M (7.79%) | 168.07K Increased by +3.93% | Mar 31, 26 |
| 6 | Bvf Inc | 3.46M (6.30%) | -19.66K Decreased by -0.57% | Mar 31, 26 |
| 7 | Morgan Stanley - Brokerage Accounts | 2.31M (4.20%) | 217.62K Increased by +9.44% | Mar 31, 26 |
| 8 | T. Rowe Price Associates, Inc. | 2.00M (3.64%) | 329.56K Increased by +16.47% | Mar 31, 26 |
| 9 | Principal Financial Group Inc | 1.75M (3.19%) | 469.55K Increased by +26.77% | Mar 31, 26 |
| 10 | Driehaus Capital Management LLC | 1.58M (2.87%) | -65.09K Decreased by -4.13% | Mar 31, 26 |
| 11 | Orbimed Advisors, LLC | 1.48M (2.69%) | 313.60K Increased by +21.26% | Mar 31, 26 |
| 12 | American Century Companies Inc | 1.44M (2.62%) | 931.07K Increased by +64.75% | Mar 31, 26 |
| 13 | Baker Bros Advisors LP | 1.43M (2.61%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 14 | Siren, L.L.C. | 1.33M (2.42%) | 250.00K Increased by +18.82% | Mar 31, 26 |
| 15 | Casdin Capital, LLC | 1.18M (2.14%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | Capitolis Liquid Global Markets LLC | 1.15M (2.10%) | 273.00K Increased by +23.71% | Mar 31, 26 |
| 17 | Citadel Advisors Llc | 772.52K (1.41%) | 328.72K Increased by +42.55% | Dec 31, 25 |
| 18 | Deerfield Management Co | 767.99K (1.40%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 19 | Pacific Heights Asset Management, LLC | 750.00K (1.37%) | 50.00K Increased by +6.67% | Mar 31, 26 |
| 20 | Rock Springs Capital Management LP | 640.22K (1.17%) | -108.02K Decreased by -16.87% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 2.91M (5.30%) | 97.96K Increased by +3.37% | Mar 31, 26 |
| 2 | T. Rowe Price Health Sciences | 997.38K (1.82%) | -320.62K Decreased by -32.15% | Apr 30, 26 |
| 3 | Xtrackers MSCI USA Swap ETF 1C | 837.23K (1.52%) | 837.23K Increased by +100.00% | Dec 31, 25 |
| 4 | American Century Heritage Inv | 767.67K (1.40%) | 767.67K Increased by +100.00% | Mar 31, 26 |
| 5 | American Century US Opport. Mid Cap Gr | 767.67K (1.40%) | 767.67K Increased by +100.00% | Mar 31, 26 |
| 6 | Fidelity Advisor Growth Opps M | 733.50K (1.34%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 7 | Fidelity Contrafund | 635.50K (1.16%) | -150.90K Decreased by -23.74% | Apr 30, 26 |
| 8 | Principal Glb Emerging Markets R5 | 625.75K (1.14%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 9 | Worldwide Healthcare Ord | 581.30K (1.06%) | 49.60K Increased by +8.53% | Feb 28, 26 |
| 10 | Vanguard Explorer Inv | 577.22K (1.05%) | -69.49K Decreased by -12.04% | Mar 31, 26 |
| 11 | Janus Henderson Global Life Sciences | 569.36K (1.04%) | -4.93K Decreased by -0.87% | Mar 31, 26 |
| 12 | Janus Henderson Global Life Sciences D | 569.36K (1.04%) | -3.33K Decreased by -0.58% | Mar 31, 26 |
| 13 | Fidelity Select Biotechnology | 542.04K (0.99%) | -22.40K Decreased by -4.13% | Apr 30, 26 |
| 14 | Fidelity Select Health Care | 540.00K (0.98%) | -60.00K Decreased by -11.11% | Apr 30, 26 |
| 15 | Janus Global Life Science AUSD | 526.49K (0.96%) | 33.72K Increased by +6.40% | Mar 31, 26 |
| 16 | Janus Henderson Glb Life Scn I2 USD | 524.43K (0.96%) | -2.06K Decreased by -0.39% | Apr 30, 26 |
| 17 | Janus Henderson Hrzn Biotec E2 USD | 482.02K (0.88%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 18 | Fidelity Advisor Biotechnology I | 481.20K (0.88%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 19 | Janus Henderson Triton D | 459.49K (0.84%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | Janus Henderson US SMID Cap Growth | 459.49K (0.84%) | -11.28K Decreased by -2.45% | Mar 31, 26 |