| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbis Allan Gray Ltd | 12.93M (2.13%) | -1.49M Decreased by -11.55% | Mar 31, 26 |
| 2 | AllianceBernstein L.P. | 9.56M (1.58%) | -1.32M Decreased by -13.81% | Mar 31, 26 |
| 3 | Paradigm Biocapital Advisors LP | 7.97M (1.31%) | 928.00K Increased by +11.65% | Mar 31, 26 |
| 4 | Arrowstreet Capital Limited Partnership | 4.98M (0.82%) | -2.73K Decreased by -0.05% | Mar 31, 26 |
| 5 | BlackRock Inc | 4.54M (0.75%) | -57.34K Decreased by -1.26% | Mar 31, 26 |
| 6 | Renaissance Technologies Corp | 4.41M (0.73%) | 921.70K Increased by +20.88% | Mar 31, 26 |
| 7 | Deep Track Capital, LP | 3.66M (0.60%) | 3.66M Increased by +100.00% | Mar 31, 26 |
| 8 | Citadel Advisors Llc | 3.57M (0.59%) | -857.47K Decreased by -24.02% | Jun 30, 25 |
| 9 | Macquarie Group Ltd | 3.25M (0.54%) | -347.52K Decreased by -10.69% | Sep 30, 23 |
| 10 | Harding Loevner L.P. | 3.23M (0.53%) | -138.54K Decreased by -4.29% | Mar 31, 26 |
| 11 | Capital Research & Mgmt Co - Division 3 | 2.57M (0.42%) | -1.85M Decreased by -71.99% | Dec 31, 24 |
| 12 | Deerfield Management Co | 2.46M (0.41%) | 2.46M Increased by +100.00% | Mar 31, 26 |
| 13 | First Trust Advisors L.P. | 2.46M (0.41%) | 1.13M Increased by +45.75% | Mar 31, 26 |
| 14 | Two Sigma Investments LLC | 2.34M (0.39%) | 1.44M Increased by +61.71% | Mar 31, 26 |
| 15 | Wellington Management Company LLP | 2.31M (0.38%) | -670.00 Decreased by -0.03% | Sep 30, 24 |
| 16 | 1832 Asset Management L.P | 2.24M (0.37%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 17 | Morgan Stanley - Brokerage Accounts | 2.18M (0.36%) | 350.26K Increased by +16.03% | Mar 31, 26 |
| 18 | Two Sigma Advisers, LLC | 1.82M (0.30%) | -152.70K Decreased by -8.39% | Jun 30, 25 |
| 19 | UBS Group AG | 1.44M (0.24%) | 1.38M Increased by +95.80% | Dec 31, 24 |
| 20 | Cubist Systematic Strategies, LLC | 1.26M (0.21%) | 665.89K Increased by +52.93% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | AllianceBernstein US L/C Growth Eqty MF | 3.95M (0.65%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | iShares Biotechnology ETF | 3.52M (0.58%) | 50.72K Increased by +1.44% | May 29, 26 |
| 3 | Orbis SICAV Intl Eq Inv | 3.09M (0.51%) | -306.17K Decreased by -9.90% | Feb 28, 26 |
| 4 | First Trust NYSE Arca Biotech ETF | 2.73M (0.45%) | -11.84K Decreased by -0.43% | May 31, 26 |
| 5 | Vanguard Health Care Inv | 2.29M (0.38%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Delaware Ivy Mid Cap Growth A | 1.98M (0.33%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | T. Rowe Price International Gr Eq SMA | 1.90M (0.31%) | 1.90M Increased by +100.00% | Dec 31, 24 |
| 8 | AB Large Cap Growth A | 1.85M (0.30%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 9 | Orbis SICAV Global Bal Instl Inv | 1.41M (0.23%) | 528.30K Increased by +37.49% | Sep 30, 25 |
| 10 | Orbis Global Equity Investor | 1.31M (0.22%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 11 | Xtrackers S&P 500 Swap ETF 1C | 1.02M (0.17%) | 1.02M Increased by +100.00% | Feb 28, 25 |
| 12 | AB US Large Cap Growth CT B | 988.04K (0.16%) | -7.08K Decreased by -0.72% | Apr 30, 26 |
| 13 | American Growth One D | 949.87K (0.16%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 14 | AB American Growth AX USD | 947.38K (0.16%) | -1.94K Decreased by -0.20% | Apr 30, 26 |
| 15 | Dynamic Power Global Growth Class | 917.30K (0.15%) | -758.10K Decreased by -82.64% | Oct 31, 23 |
| 16 | Pictet-Biotech P USD | 718.47K (0.12%) | 2.83K Increased by +0.39% | Feb 28, 26 |
| 17 | Orbis Optimal (US$) Fund | 693.66K (0.11%) | 27.07K Increased by +3.90% | Sep 30, 25 |
| 18 | Orbis OEIC Global Balanced Fixed Fee | 618.96K (0.10%) | 88.98K Increased by +14.38% | Nov 30, 25 |
| 19 | Federated Hermes Kaufmann Growth | 520.70K (0.09%) | 98.20K Increased by +18.86% | Mar 31, 26 |
| 20 | Federated Hermes Kaufmann R | 520.70K (0.09%) | 98.20K Increased by +18.86% | Mar 31, 26 |