| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | TANG CAPITAL MANAGEMENT LLC | 2.16M (4.85%) | 1.46M Increased by +67.61% | Dec 31, 24 |
| 2 | FMR Inc | 1.59M (3.58%) | -4.10K Decreased by -0.26% | Dec 31, 24 |
| 3 | Bvf Inc | 1.57M (3.52%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Deerfield Management Co | 1.41M (3.17%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Prosight Management, LP | 1.02M (2.30%) | -3.84K Decreased by -0.37% | Dec 31, 24 |
| 6 | Logos Global Management LP | 800.00K (1.80%) | 800.00K Increased by +100.00% | Sep 30, 24 |
| 7 | Deep Track Capital, LP | 780.78K (1.75%) | 780.78K Increased by +100.00% | Dec 31, 24 |
| 8 | Segall Bryant & Hamill | 685.87K (1.54%) | -19.78K Decreased by -2.88% | Dec 31, 24 |
| 9 | Finepoint Capital LP | 674.76K (1.52%) | 117.00K Increased by +17.34% | Dec 31, 24 |
| 10 | PRIMECAP Management Company | 631.21K (1.42%) | -89.03K Decreased by -14.10% | Dec 31, 24 |
| 11 | Hudson Bay Capital Management LP | 554.30K (1.24%) | 44.30K Increased by +7.99% | Dec 31, 24 |
| 12 | BlackRock Inc | 424.66K (0.95%) | -79.60K Decreased by -18.74% | Dec 31, 24 |
| 13 | Wellington Management Company LLP | 345.05K (0.77%) | -129.83K Decreased by -37.63% | Jun 30, 24 |
| 14 | Renaissance Technologies Corp | 296.10K (0.66%) | 4.42K Increased by +1.49% | Dec 31, 24 |
| 15 | Newtyn Management LLC | 270.00K (0.61%) | -230.00K Decreased by -85.19% | Dec 31, 24 |
| 16 | Millennium Management LLC | 267.35K (0.60%) | -74.28K Decreased by -27.79% | Sep 30, 24 |
| 17 | Stonepine Capital Management Llc | 200.00K (0.45%) | -278.66K Decreased by -139.33% | Dec 31, 24 |
| 18 | Vestal Point Capital LP | 180.00K (0.40%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 19 | Point72 Asset Management, L.P. | 173.30K (0.39%) | -707.37K Decreased by -408.18% | Sep 30, 23 |
| 20 | Greenlight Capital, Inc | 162.58K (0.37%) | 6.20K Increased by +3.81% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Contrafund® | 1.24M (2.79%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 2 | Fidelity Contrafund | 887.83K (1.99%) | -226.48K Decreased by -25.51% | May 31, 24 |
| 3 | PRIMECAP Odyssey Aggressive Growth | 531.30K (1.19%) | -73.40K Decreased by -13.82% | Dec 31, 24 |
| 4 | VIP Growth Initial | 453.50K (1.02%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 5 | Fidelity Advisor Equity Growth I | 431.37K (0.97%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 6 | Fidelity Advisor® Equity Growth I | 404.33K (0.91%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 7 | Fidelity VIP Growth Initial | 395.70K (0.89%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 8 | Fidelity Contrafund Commingled Pl O | 389.12K (0.87%) | -98.50K Decreased by -25.31% | May 31, 24 |
| 9 | Fidelity Capital Appreciation | 354.70K (0.80%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 10 | Fidelity® Capital Appreciation | 354.70K (0.80%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 11 | Fidelity® Contrafund® K6 | 335.75K (0.75%) | -1.22K Decreased by -0.36% | Nov 30, 23 |
| 12 | Wellington Global Hlthcr Eq USD G Ac | 246.19K (0.55%) | -5.30K Decreased by -2.15% | May 31, 24 |
| 13 | Fidelity Contrafund K6 | 231.22K (0.52%) | -58.54K Decreased by -25.32% | May 31, 24 |
| 14 | Fidelity Growth Discovery | 229.55K (0.52%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 15 | iShares Biotechnology ETF | 212.80K (0.48%) | -2.37K Decreased by -1.11% | Mar 31, 25 |
| 16 | Fidelity® Growth Discovery | 207.25K (0.47%) | 10.50K Increased by +5.07% | Nov 30, 23 |
| 17 | Fidelity Advisor® New Insights I | 173.94K (0.39%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | Segall Bryant & Hamill Sm Cp Val Ins | 172.80K (0.39%) | -2.14K Decreased by -1.24% | Feb 28, 25 |
| 19 | VIP Contrafund Initial | 143.88K (0.32%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Fidelity Advisor New Insights I | 124.17K (0.28%) | -31.49K Decreased by -25.36% | May 31, 24 |