| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 5.76M (12.93%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | FMR Inc | 4.32M (9.70%) | 28.50K Increased by +0.66% | Sep 30, 23 |
| 3 | Bvf Inc | 1.92M (4.30%) | -250.00K Decreased by -13.05% | Sep 30, 23 |
| 4 | Stonepine Capital Management Llc | 802.54K (1.80%) | 119.88K Increased by +14.94% | Sep 30, 23 |
| 5 | Segall Bryant & Hamill | 737.99K (1.66%) | 346.63K Increased by +46.97% | Sep 30, 23 |
| 6 | Prosight Management, LP | 730.21K (1.64%) | 312.71K Increased by +42.82% | Sep 30, 23 |
| 7 | Hudson Bay Capital Management LP | 700.00K (1.57%) | 375.00K Increased by +53.57% | Sep 30, 23 |
| 8 | PRIMECAP Management Company | 678.88K (1.53%) | 9.20K Increased by +1.36% | Dec 31, 23 |
| 9 | Wellington Management Company LLP | 495.22K (1.11%) | 18.55K Increased by +3.75% | Dec 31, 23 |
| 10 | Citadel Advisors Llc | 469.87K (1.06%) | 236.58K Increased by +50.35% | Sep 30, 23 |
| 11 | Finepoint Capital LP | 458.66K (1.03%) | 51.80K Increased by +11.29% | Sep 30, 23 |
| 12 | BlackRock Inc | 440.61K (0.99%) | -41.26K Decreased by -9.36% | Sep 30, 23 |
| 13 | Renaissance Technologies Corp | 263.20K (0.59%) | -18.60K Decreased by -7.07% | Dec 31, 23 |
| 14 | Newtyn Management LLC | 218.09K (0.49%) | -56.91K Decreased by -26.10% | Dec 31, 23 |
| 15 | Point72 Asset Management, L.P. | 173.30K (0.39%) | -707.37K Decreased by -408.18% | Sep 30, 23 |
| 16 | Greenlight Capital, Inc | 162.58K (0.37%) | 6.20K Increased by +3.81% | Dec 31, 23 |
| 17 | NORGES BANK | 120.00K (0.27%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 18 | AlphaCentric Advisors, LLC | 105.00K (0.24%) | 6.00K Increased by +5.71% | Sep 30, 23 |
| 19 | Citigroup Inc | 90.69K (0.20%) | 89.45K Increased by +98.64% | Sep 30, 23 |
| 20 | TANG CAPITAL MANAGEMENT LLC | 89.65K (0.20%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Contrafund | 1.25M (2.81%) | 6.11K Increased by +0.49% | Dec 31, 23 |
| 2 | Fidelity® Contrafund® | 1.24M (2.79%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 3 | PRIMECAP Odyssey Aggressive Growth | 571.33K (1.28%) | 9.20K Increased by +1.61% | Dec 31, 23 |
| 4 | Fidelity Contrafund Commingled Pl O | 534.28K (1.20%) | 1.22K Increased by +0.23% | Nov 30, 23 |
| 5 | VIP Growth Initial | 453.50K (1.02%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 6 | Fidelity VIP Growth Initial | 431.80K (0.97%) | -21.70K Decreased by -5.03% | Dec 31, 23 |
| 7 | Fidelity Advisor Equity Growth I | 404.33K (0.91%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 8 | Fidelity Advisor® Equity Growth I | 404.33K (0.91%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 9 | iShares Biotechnology ETF | 356.24K (0.80%) | -327.00 Decreased by -0.09% | Jan 31, 24 |
| 10 | Fidelity Capital Appreciation | 354.70K (0.80%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 11 | Fidelity® Capital Appreciation | 354.70K (0.80%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 12 | Fidelity® Contrafund® K6 | 335.75K (0.75%) | -1.22K Decreased by -0.36% | Nov 30, 23 |
| 13 | Fidelity Contrafund K6 | 329.64K (0.74%) | -6.11K Decreased by -1.85% | Dec 31, 23 |
| 14 | Wellington Global Hlthcr Eq USD G Ac | 273.86K (0.62%) | -6.77K Decreased by -2.47% | Dec 31, 23 |
| 15 | Segall Bryant & Hamill Sm Cp Val Ins | 252.89K (0.57%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 16 | Fidelity Growth Discovery | 207.25K (0.47%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 17 | Fidelity® Growth Discovery | 207.25K (0.47%) | 10.50K Increased by +5.07% | Nov 30, 23 |
| 18 | Fidelity Advisor New Insights I | 173.94K (0.39%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 19 | Fidelity Advisor® New Insights I | 173.94K (0.39%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Fidelity VIP Contrafund Initial | 143.88K (0.32%) | 0.00 Increased by 0.00% | Dec 31, 23 |