| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 28.80M (11.54%) | 212.21K Increased by +0.74% | Sep 30, 24 |
| 2 | Perceptive Advisors LLC | 28.06M (11.25%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | BlackRock Inc | 24.37M (9.77%) | 1.52M Increased by +6.25% | Jun 30, 24 |
| 4 | Wellington Management Company LLP | 23.96M (9.61%) | 2.86M Increased by +11.92% | Sep 30, 24 |
| 5 | venBio Select Advisor LLC | 23.18M (9.29%) | -4.22M Decreased by -18.23% | Sep 30, 24 |
| 6 | William Blair Investment Management, LLC | 15.58M (6.25%) | 2.58M Increased by +16.55% | Sep 30, 24 |
| 7 | JPMorgan Chase & Co | 12.92M (5.18%) | -1.95M Decreased by -15.10% | Sep 30, 24 |
| 8 | State Street Corporation | 12.44M (4.99%) | -720.58K Decreased by -5.79% | Mar 31, 24 |
| 9 | State Street Corp | 10.97M (4.40%) | -46.22K Decreased by -0.42% | Sep 30, 24 |
| 10 | Redmile Group, LLC | 8.25M (3.31%) | -2.35M Decreased by -28.48% | Sep 30, 24 |
| 11 | Palo Alto Investors, LLC | 8.15M (3.26%) | -884.53K Decreased by -10.86% | Sep 30, 24 |
| 12 | Macquarie Group Ltd | 6.97M (2.79%) | -151.34K Decreased by -2.17% | Sep 30, 24 |
| 13 | Geode Capital Management, LLC | 6.60M (2.65%) | 80.93K Increased by +1.23% | Sep 30, 24 |
| 14 | HHG PLC | 6.34M (2.54%) | -6.90M Decreased by -108.85% | Sep 30, 24 |
| 15 | Fiera Capital Corporation | 5.28M (2.12%) | 58.11K Increased by +1.10% | Jun 30, 24 |
| 16 | Pictet Asset Manangement SA | 4.22M (1.69%) | -2.55M Decreased by -60.51% | Jun 30, 24 |
| 17 | Morgan Stanley - Brokerage Accounts | 4.22M (1.69%) | -5.77M Decreased by -136.88% | Sep 30, 24 |
| 18 | Artal Group S A | 4.06M (1.63%) | -500.00K Decreased by -12.31% | Sep 30, 23 |
| 19 | American Century Companies Inc | 3.90M (1.57%) | -18.81K Decreased by -0.48% | Sep 30, 24 |
| 20 | Nuveen Asset Management, LLC | 3.65M (1.46%) | 1.75M Increased by +47.93% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 18.59M (7.45%) | 2.31M Increased by +12.41% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 9.32M (3.74%) | -51.92K Decreased by -0.56% | Oct 31, 24 |
| 3 | iShares Russell 2000 ETF | 8.13M (3.26%) | -16.98K Decreased by -0.21% | Nov 27, 24 |
| 4 | Vanguard Small Cap Index | 7.44M (2.98%) | 14.55K Increased by +0.20% | Oct 31, 24 |
| 5 | Delaware US Small Cap Core Equity (SMA) | 5.30M (2.12%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 6 | Macquarie US Small Cap Core Equity | 5.30M (2.12%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 7 | Delaware Small Cap Core I | 5.13M (2.06%) | -31.80K Decreased by -0.62% | Sep 30, 24 |
| 8 | Janus Henderson Opportunistic Alpha MA | 4.58M (1.84%) | 4.58M Increased by +99.99% | Jun 30, 24 |
| 9 | Janus Henderson US Opportunistic Alpha | 4.58M (1.84%) | -565.02K Decreased by -12.34% | Jun 30, 24 |
| 10 | SPDR® S&P Biotech ETF | 4.46M (1.79%) | -135.54K Decreased by -3.04% | Nov 27, 24 |
| 11 | Vanguard Small Cap Growth Index Inv | 4.09M (1.64%) | -6.04K Decreased by -0.15% | Oct 31, 24 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 3.96M (1.59%) | -14.75K Decreased by -0.37% | Oct 31, 24 |
| 13 | American Century Heritage Inv | 3.49M (1.40%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | American Century US Opport. Mid Cap Gr | 3.49M (1.40%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | JPMorgan Small Cap Growth A | 3.28M (1.32%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | JPM Global Healthcare C (acc) USD | 3.27M (1.31%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 17 | Fidelity Small Cap Index | 2.98M (1.19%) | -19.63K Decreased by -0.66% | Sep 30, 24 |
| 18 | JPM US Mid Cap Growth-Composite | 2.94M (1.18%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 19 | JPMorgan Mid Cap Growth I | 2.94M (1.18%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | Pictet-Biotech P USD | 2.90M (1.16%) | -545.90K Decreased by -18.85% | Jul 31, 23 |