| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 28.80M (11.95%) | 212.21K Increased by +0.74% | Sep 30, 24 |
| 2 | Perceptive Advisors LLC | 28.06M (11.64%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | BlackRock Inc | 24.37M (10.11%) | 1.52M Increased by +6.25% | Jun 30, 24 |
| 4 | venBio Select Advisor LLC | 23.18M (9.61%) | -4.22M Decreased by -18.23% | Sep 30, 24 |
| 5 | Wellington Management Company LLP | 21.11M (8.76%) | 2.30M Increased by +10.92% | Jun 30, 24 |
| 6 | William Blair Investment Management, LLC | 15.58M (6.46%) | 2.58M Increased by +16.55% | Sep 30, 24 |
| 7 | JPMorgan Chase & Co | 14.87M (6.17%) | -820.38K Decreased by -5.52% | Jun 30, 24 |
| 8 | HHG PLC | 13.23M (5.49%) | -583.12K Decreased by -4.41% | Jun 30, 24 |
| 9 | State Street Corporation | 12.44M (5.16%) | -720.58K Decreased by -5.79% | Mar 31, 24 |
| 10 | State Street Corp | 11.02M (4.57%) | -1.43M Decreased by -12.94% | Jun 30, 24 |
| 11 | Morgan Stanley - Brokerage Accounts | 9.99M (4.14%) | -9.42M Decreased by -94.38% | Jun 30, 24 |
| 12 | Palo Alto Investors, LLC | 9.03M (3.75%) | -314.26K Decreased by -3.48% | Jun 30, 24 |
| 13 | Redmile Group, LLC | 8.25M (3.42%) | -2.35M Decreased by -28.48% | Sep 30, 24 |
| 14 | Macquarie Group Ltd | 7.12M (2.95%) | 50.49K Increased by +0.71% | Jun 30, 24 |
| 15 | Geode Capital Management, LLC | 6.52M (2.70%) | 308.21K Increased by +4.73% | Jun 30, 24 |
| 16 | Fiera Capital Corporation | 5.28M (2.19%) | 58.11K Increased by +1.10% | Jun 30, 24 |
| 17 | Goldman Sachs Group Inc | 4.25M (1.76%) | 1.73M Increased by +40.69% | Dec 31, 23 |
| 18 | Pictet Asset Manangement SA | 4.22M (1.75%) | -2.55M Decreased by -60.51% | Jun 30, 24 |
| 19 | Artal Group S A | 4.06M (1.69%) | -500.00K Decreased by -12.31% | Sep 30, 23 |
| 20 | American Century Companies Inc | 3.90M (1.62%) | -18.81K Decreased by -0.48% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 18.59M (7.71%) | 2.31M Increased by +12.41% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 9.32M (3.87%) | -51.92K Decreased by -0.56% | Oct 31, 24 |
| 3 | iShares Russell 2000 ETF | 7.53M (3.12%) | -16.93K Decreased by -0.22% | Oct 31, 24 |
| 4 | Vanguard Small Cap Index | 7.44M (3.08%) | 14.55K Increased by +0.20% | Oct 31, 24 |
| 5 | Delaware US Small Cap Core Equity (SMA) | 5.30M (2.20%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 6 | Macquarie US Small Cap Core Equity | 5.30M (2.20%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 7 | Delaware Small Cap Core I | 5.13M (2.13%) | -31.80K Decreased by -0.62% | Sep 30, 24 |
| 8 | Janus Henderson Opportunistic Alpha MA | 4.58M (1.90%) | 4.58M Increased by +99.99% | Jun 30, 24 |
| 9 | Janus Henderson US Opportunistic Alpha | 4.58M (1.90%) | -565.02K Decreased by -12.34% | Jun 30, 24 |
| 10 | SPDR® S&P Biotech ETF | 4.38M (1.82%) | -63.25K Decreased by -1.44% | Oct 31, 24 |
| 11 | Vanguard Small Cap Growth Index Inv | 4.09M (1.70%) | -6.04K Decreased by -0.15% | Oct 31, 24 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 3.98M (1.65%) | -91.21K Decreased by -2.29% | Sep 30, 24 |
| 13 | American Century Heritage Inv | 3.49M (1.45%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | American Century US Opport. Mid Cap Gr | 3.49M (1.45%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | JPMorgan Small Cap Growth A | 3.28M (1.36%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | JPM Global Healthcare C (acc) USD | 3.27M (1.35%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 17 | Fidelity Small Cap Index | 3.00M (1.24%) | -71.04K Decreased by -2.37% | Aug 31, 24 |
| 18 | JPM US Mid Cap Growth-Composite | 2.94M (1.22%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 19 | JPMorgan Mid Cap Growth I | 2.94M (1.22%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | Pictet-Biotech P USD | 2.90M (1.20%) | -545.90K Decreased by -18.85% | Jul 31, 23 |