| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 29.41M (10.20%) | 356.97K Increased by +1.21% | Jun 30, 25 |
| 2 | Wellington Management Company LLP | 29.12M (10.11%) | -76.66K Decreased by -0.26% | Jun 30, 25 |
| 3 | BlackRock Inc | 27.82M (9.65%) | -83.77K Decreased by -0.30% | Mar 31, 25 |
| 4 | venBio Select Advisor LLC | 18.00M (6.25%) | -2.50M Decreased by -13.89% | Jun 30, 25 |
| 5 | William Blair Investment Management, LLC | 14.64M (5.08%) | -136.49K Decreased by -0.93% | Jun 30, 25 |
| 6 | State Street Corporation | 12.44M (4.32%) | -720.58K Decreased by -5.79% | Mar 31, 24 |
| 7 | Redmile Group, LLC | 9.53M (3.31%) | 2.48M Increased by +26.00% | Mar 31, 25 |
| 8 | State Street Corp | 9.52M (3.30%) | -842.21K Decreased by -8.85% | Mar 31, 25 |
| 9 | Citadel Advisors Llc | 7.84M (2.72%) | -400.41K Decreased by -5.11% | Mar 31, 25 |
| 10 | Perceptive Advisors LLC | 7.41M (2.57%) | -14.05M Decreased by -189.56% | Jun 30, 25 |
| 11 | Macquarie Group Ltd | 6.82M (2.36%) | 187.06K Increased by +2.74% | Mar 31, 25 |
| 12 | Geode Capital Management, LLC | 6.76M (2.35%) | 152.84K Increased by +2.26% | Mar 31, 25 |
| 13 | D. E. Shaw & Co LP | 6.36M (2.21%) | 4.07M Increased by +64.00% | Jun 30, 25 |
| 14 | Palo Alto Investors, LLC | 5.61M (1.95%) | -1.73M Decreased by -30.91% | Jun 30, 25 |
| 15 | Bank of America Corp | 5.60M (1.94%) | 1.56M Increased by +27.90% | Mar 31, 25 |
| 16 | Fiera Capital Corporation | 5.28M (1.83%) | 58.11K Increased by +1.10% | Jun 30, 24 |
| 17 | JPMorgan Chase & Co | 4.89M (1.70%) | -2.32M Decreased by -47.40% | Mar 31, 25 |
| 18 | Goldman Sachs Group Inc | 4.34M (1.51%) | 1.64M Increased by +37.75% | Jun 30, 25 |
| 19 | Vestal Point Capital LP | 4.28M (1.48%) | 925.00K Increased by +21.64% | Mar 31, 25 |
| 20 | Morgan Stanley - Brokerage Accounts | 4.22M (1.46%) | -5.77M Decreased by -136.88% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 20.89M (7.25%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 9.51M (3.30%) | -200.71K Decreased by -2.11% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 9.38M (3.25%) | 10.28K Increased by +0.11% | Sep 30, 24 |
| 4 | Vanguard Small Cap Index | 7.47M (2.59%) | -48.88K Decreased by -0.65% | Jul 31, 25 |
| 5 | iShares Russell 2000 ETF | 6.55M (2.27%) | -124.42K Decreased by -1.90% | Jul 31, 25 |
| 6 | Macquarie Small Cap Core I | 5.62M (1.95%) | 614.64K Increased by +10.94% | Jun 30, 25 |
| 7 | Delaware US Small Cap Core Equity (SMA) | 5.30M (1.84%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 8 | Macquarie US Small Cap Core Equity | 5.30M (1.84%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 9 | Delaware Small Cap Core I | 5.13M (1.78%) | -31.80K Decreased by -0.62% | Sep 30, 24 |
| 10 | SPDR® S&P Biotech ETF | 5.07M (1.76%) | 151.29K Increased by +2.99% | Jul 31, 25 |
| 11 | Janus Henderson Opportunistic Alpha MA | 4.58M (1.59%) | 4.58M Increased by +99.99% | Jun 30, 24 |
| 12 | Janus Henderson US Opportunistic Alpha | 4.58M (1.59%) | -565.02K Decreased by -12.34% | Jun 30, 24 |
| 13 | Vanguard Small Cap Growth Index Inv | 4.23M (1.47%) | -1.21K Decreased by -0.03% | Jul 31, 25 |
| 14 | American Century Heritage Inv | 3.49M (1.21%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | American Century US Opport. Mid Cap Gr | 3.49M (1.21%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | JPM Global Healthcare C (acc) USD | 3.27M (1.13%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 17 | Vanguard Institutional Extnd Mkt Idx Tr | 2.98M (1.04%) | -1.31M Decreased by -43.94% | Jul 31, 25 |
| 18 | Fidelity Small Cap Index | 2.97M (1.03%) | 3.66K Increased by +0.12% | May 31, 25 |
| 19 | JPM US Mid Cap Growth-Composite | 2.94M (1.02%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | JPMorgan Mid Cap Growth I | 2.94M (1.02%) | 0.00 Increased by 0.00% | Sep 30, 24 |