| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Wellington Management Company LLP | 29.20M (11.05%) | 738.62K Increased by +2.53% | Mar 31, 25 |
| 2 | Vanguard Group Inc | 29.05M (10.99%) | -208.34K Decreased by -0.72% | Mar 31, 25 |
| 3 | BlackRock Inc | 27.82M (10.53%) | -83.77K Decreased by -0.30% | Mar 31, 25 |
| 4 | Perceptive Advisors LLC | 21.46M (8.12%) | -2.78M Decreased by -12.96% | Mar 31, 25 |
| 5 | venBio Select Advisor LLC | 20.50M (7.76%) | -2.67M Decreased by -13.05% | Mar 31, 25 |
| 6 | William Blair Investment Management, LLC | 14.64M (5.54%) | -136.49K Decreased by -0.93% | Jun 30, 25 |
| 7 | State Street Corporation | 12.44M (4.71%) | -720.58K Decreased by -5.79% | Mar 31, 24 |
| 8 | Redmile Group, LLC | 9.53M (3.61%) | 2.48M Increased by +26.00% | Mar 31, 25 |
| 9 | State Street Corp | 9.52M (3.60%) | -842.21K Decreased by -8.85% | Mar 31, 25 |
| 10 | Citadel Advisors Llc | 7.84M (2.97%) | -400.41K Decreased by -5.11% | Mar 31, 25 |
| 11 | Palo Alto Investors, LLC | 7.35M (2.78%) | -317.48K Decreased by -4.32% | Mar 31, 25 |
| 12 | Macquarie Group Ltd | 6.82M (2.58%) | 187.06K Increased by +2.74% | Mar 31, 25 |
| 13 | Geode Capital Management, LLC | 6.76M (2.56%) | 152.84K Increased by +2.26% | Mar 31, 25 |
| 14 | Bank of America Corp | 5.60M (2.12%) | 1.56M Increased by +27.90% | Mar 31, 25 |
| 15 | Fiera Capital Corporation | 5.28M (2.00%) | 58.11K Increased by +1.10% | Jun 30, 24 |
| 16 | JPMorgan Chase & Co | 4.89M (1.85%) | -2.32M Decreased by -47.40% | Mar 31, 25 |
| 17 | Vestal Point Capital LP | 4.28M (1.62%) | 925.00K Increased by +21.64% | Mar 31, 25 |
| 18 | Pictet Asset Manangement SA | 4.22M (1.60%) | -2.55M Decreased by -60.51% | Jun 30, 24 |
| 19 | Morgan Stanley - Brokerage Accounts | 4.22M (1.60%) | -5.77M Decreased by -136.88% | Sep 30, 24 |
| 20 | Artal Group S A | 4.06M (1.54%) | -500.00K Decreased by -12.31% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 20.89M (7.91%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 9.71M (3.67%) | 50.91K Increased by +0.52% | Jun 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 9.38M (3.55%) | 10.28K Increased by +0.11% | Sep 30, 24 |
| 4 | Vanguard Small Cap Index | 7.52M (2.85%) | -41.98K Decreased by -0.56% | Jun 30, 25 |
| 5 | iShares Russell 2000 ETF | 6.67M (2.52%) | -107.83K Decreased by -1.62% | Jul 30, 25 |
| 6 | Macquarie Small Cap Core I | 5.62M (2.13%) | 614.64K Increased by +10.94% | Jun 30, 25 |
| 7 | Delaware US Small Cap Core Equity (SMA) | 5.30M (2.01%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 8 | Macquarie US Small Cap Core Equity | 5.30M (2.01%) | -62.03K Decreased by -1.17% | Mar 31, 24 |
| 9 | Delaware Small Cap Core I | 5.13M (1.94%) | -31.80K Decreased by -0.62% | Sep 30, 24 |
| 10 | SPDR® S&P Biotech ETF | 5.04M (1.91%) | 124.19K Increased by +2.46% | Jul 31, 25 |
| 11 | Janus Henderson Opportunistic Alpha MA | 4.58M (1.73%) | 4.58M Increased by +99.99% | Jun 30, 24 |
| 12 | Janus Henderson US Opportunistic Alpha | 4.58M (1.73%) | -565.02K Decreased by -12.34% | Jun 30, 24 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 4.30M (1.63%) | 91.72K Increased by +2.14% | Jun 30, 25 |
| 14 | Vanguard Small Cap Growth Index Inv | 4.23M (1.60%) | 61.78K Increased by +1.46% | Jun 30, 25 |
| 15 | American Century Heritage Inv | 3.49M (1.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | American Century US Opport. Mid Cap Gr | 3.49M (1.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | JPM Global Healthcare C (acc) USD | 3.27M (1.24%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 18 | Fidelity Small Cap Index | 2.97M (1.12%) | 3.66K Increased by +0.12% | May 31, 25 |
| 19 | JPM US Mid Cap Growth-Composite | 2.94M (1.11%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | JPMorgan Mid Cap Growth I | 2.94M (1.11%) | 0.00 Increased by 0.00% | Sep 30, 24 |