| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbimed Advisors, LLC | 7.96M (14.94%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | FMR Inc | 6.83M (12.82%) | -278.39K Decreased by -4.08% | Mar 31, 26 |
| 3 | Polar Capital Holdings PLC | 5.07M (9.51%) | 1.55M Increased by +30.64% | Mar 31, 26 |
| 4 | BlackRock Inc | 3.68M (6.92%) | 71.38K Increased by +1.94% | Mar 31, 26 |
| 5 | COMMODORE CAPITAL LP | 3.27M (6.15%) | -1.42M Decreased by -43.29% | Mar 31, 26 |
| 6 | Vestal Point Capital LP | 3.25M (6.10%) | -580.00K Decreased by -17.85% | Mar 31, 26 |
| 7 | Vanguard Group Inc | 2.80M (5.26%) | 248.65K Increased by +8.88% | Dec 31, 25 |
| 8 | Bellevue Group AG | 2.32M (4.36%) | 2.32M Increased by +100.00% | Mar 31, 26 |
| 9 | Vanguard Capital Management, LLC | 2.17M (4.07%) | 2.17M Increased by +100.00% | Mar 31, 26 |
| 10 | Fairmount Funds Management LLC | 1.86M (3.48%) | -1.86M Decreased by -100.01% | Mar 31, 26 |
| 11 | Citadel Advisors Llc | 1.74M (3.27%) | 319.57K Increased by +18.32% | Mar 31, 26 |
| 12 | VR Adviser, LLC | 1.73M (3.24%) | -1.50M Decreased by -86.89% | Mar 31, 26 |
| 13 | Point72 Asset Management, L.P. | 1.50M (2.82%) | 464.19K Increased by +30.85% | Dec 31, 25 |
| 14 | Novo A/S | 1.28M (2.40%) | -200.00K Decreased by -15.63% | Mar 31, 26 |
| 15 | State Street Corp | 1.09M (2.05%) | 38.24K Increased by +3.51% | Mar 31, 26 |
| 16 | Geode Capital Management, LLC | 1.07M (2.00%) | 17.70K Increased by +1.66% | Mar 31, 26 |
| 17 | Soleus Capital Management, L.P. | 1.02M (1.92%) | 1.02M Increased by +100.00% | Dec 31, 25 |
| 18 | Blackstone Inc | 954.95K (1.79%) | -365.65K Decreased by -38.29% | Dec 31, 25 |
| 19 | Pictet Asset Manangement SA | 929.54K (1.75%) | -373.69K Decreased by -40.20% | Mar 31, 26 |
| 20 | Baker Bros Advisors LP | 905.19K (1.70%) | 633.78K Increased by +70.02% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Polar Capital Healthcare Opports Inc | 2.80M (5.25%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | Polar Capital Biotech S Inc | 2.14M (4.02%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.62M (3.05%) | 5.16K Increased by +0.32% | Apr 30, 26 |
| 4 | Fidelity Select Health Care | 1.15M (2.16%) | -100.00K Decreased by -8.70% | Apr 30, 26 |
| 5 | Fidelity Small Cap Growth | 1.07M (2.01%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 6 | iShares Russell 2000 ETF | 943.53K (1.77%) | 8.74K Increased by +0.93% | May 29, 26 |
| 7 | Pictet-Biotech P USD | 754.73K (1.42%) | -72.50K Decreased by -9.61% | Feb 28, 26 |
| 8 | Fidelity Stock Selector Small Cap | 653.09K (1.23%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 9 | Fidelity Advisor Health Care I | 580.00K (1.09%) | -48.00K Decreased by -8.28% | Apr 30, 26 |
| 10 | Fidelity Small Cap Growth K6 | 569.80K (1.07%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 501.95K (0.94%) | 4.30K Increased by +0.86% | Apr 30, 26 |
| 12 | Candriam Eqs L Biotech C USD Cap | 453.02K (0.85%) | 76.85K Increased by +16.96% | Nov 30, 25 |
| 13 | Fidelity Small Cap Index | 386.04K (0.72%) | 477.00 Increased by +0.12% | Mar 31, 26 |
| 14 | Pictet-Global Megatrend Sel I USD | 340.40K (0.64%) | 340.40K Increased by +100.00% | Jan 31, 26 |
| 15 | Fidelity Select Biotechnology | 340.07K (0.64%) | -23.20K Decreased by -6.82% | Apr 30, 26 |
| 16 | Fidelity Advisor Biotechnology I | 328.86K (0.62%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 17 | Fidelity Series Small Cap Opps | 325.13K (0.61%) | -7.60K Decreased by -2.34% | Mar 31, 26 |
| 18 | iShares Biotechnology ETF | 319.99K (0.60%) | 6.12K Increased by +1.91% | May 29, 26 |
| 19 | iShares Russell 2000 Growth ETF | 319.91K (0.60%) | -2.08K Decreased by -0.65% | May 29, 26 |
| 20 | AB Small Cap Growth A | 317.19K (0.60%) | -14.31K Decreased by -4.51% | Apr 30, 26 |