| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 9.03M (12.88%) | 3.71M Increased by +41.08% | Sep 30, 24 |
| 2 | BlackRock Inc | 7.79M (11.12%) | 407.13K Increased by +5.22% | Sep 30, 24 |
| 3 | Vanguard Group Inc | 6.86M (9.80%) | 2.15M Increased by +31.27% | Sep 30, 24 |
| 4 | RTW INVESTMENTS, LLC | 6.82M (9.73%) | 431.50K Increased by +6.33% | Sep 30, 24 |
| 5 | HHG PLC | 6.81M (9.72%) | 2.19M Increased by +32.13% | Sep 30, 24 |
| 6 | RA Capital Management, LLC | 6.38M (9.11%) | 331.94K Increased by +5.20% | Sep 30, 24 |
| 7 | FCPM III SERVICES BV | 5.95M (8.50%) | -1.89M Decreased by -31.76% | Sep 30, 24 |
| 8 | State Street Corporation | 4.19M (5.99%) | 1.86M Increased by +44.27% | Mar 31, 24 |
| 9 | State Street Corp | 3.64M (5.20%) | 440.89K Increased by +12.11% | Sep 30, 24 |
| 10 | Deep Track Capital, LP | 3.28M (4.68%) | -718.00K Decreased by -21.88% | Sep 30, 24 |
| 11 | Citadel Advisors Llc | 2.94M (4.20%) | -1.38M Decreased by -46.84% | Sep 30, 24 |
| 12 | TCG Crossover Management, LLC | 2.65M (3.78%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | T. Rowe Price Associates, Inc. | 2.64M (3.76%) | 270.22K Increased by +10.25% | Sep 30, 24 |
| 14 | Adage Capital Partners Gp LLC | 2.40M (3.43%) | -925.03K Decreased by -38.50% | Sep 30, 24 |
| 15 | VR Adviser, LLC | 2.17M (3.10%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | Goldman Sachs Group Inc | 2.10M (2.99%) | 434.66K Increased by +20.74% | Jun 30, 24 |
| 17 | Vida Ventures Advisors, LLC | 2.07M (2.96%) | -145.25K Decreased by -7.00% | Dec 31, 23 |
| 18 | Morgan Stanley - Brokerage Accounts | 2.02M (2.89%) | 1.91M Increased by +94.67% | Dec 31, 23 |
| 19 | Holocene Advisors, LP | 1.98M (2.83%) | -93.71K Decreased by -4.73% | Sep 30, 24 |
| 20 | Geode Capital Management, LLC | 1.86M (2.65%) | 84.76K Increased by +4.56% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.63M (3.76%) | 3.17K Increased by +0.12% | Dec 31, 24 |
| 2 | iShares Russell 2000 ETF | 2.22M (3.17%) | -8.53K Decreased by -0.38% | Dec 31, 24 |
| 3 | SPDR® S&P Biotech ETF | 1.90M (2.71%) | -33.80K Decreased by -1.78% | Dec 31, 24 |
| 4 | Fidelity Growth Compy Commingled Pl S | 1.82M (2.59%) | 2.53K Increased by +0.14% | Nov 30, 24 |
| 5 | Fidelity Growth Compy Commingled Pl O | 1.79M (2.55%) | 348.61K Increased by +19.51% | Aug 31, 24 |
| 6 | Janus Henderson Global Life Sciences D | 1.43M (2.05%) | 7.37K Increased by +0.51% | Nov 30, 24 |
| 7 | Janus Henderson Global Life Sciences | 1.42M (2.03%) | 227.22K Increased by +15.95% | Sep 30, 24 |
| 8 | Fidelity Growth Company Fund | 1.33M (1.90%) | -3.24K Decreased by -0.24% | Nov 30, 24 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 1.20M (1.71%) | 25.24K Increased by +2.10% | Dec 31, 24 |
| 10 | Janus Henderson Glb Life Scn I2 USD | 1.14M (1.63%) | 48.50K Increased by +4.26% | Nov 30, 24 |
| 11 | RTW Biotech Opportunities Ord | 1.11M (1.59%) | 1.11M Increased by +100.00% | Jun 30, 24 |
| 12 | Janus Global Life Science AUSD | 1.06M (1.51%) | 188.92K Increased by +17.84% | Sep 30, 24 |
| 13 | Vanguard Small Cap Index | 1.04M (1.48%) | -41.39K Decreased by -3.99% | Dec 31, 24 |
| 14 | T. Rowe Price New Horizons | 984.05K (1.40%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | US Small-Cap Growth II Equity Comp | 984.05K (1.40%) | -846.00 Decreased by -0.09% | Dec 31, 24 |
| 16 | Janus Selection Global Life Science AUSD | 870.12K (1.24%) | 375.63K Increased by +43.17% | Jun 30, 24 |
| 17 | T. Rowe Price Health Sciences | 854.39K (1.22%) | -38.53K Decreased by -4.51% | Aug 31, 24 |
| 18 | Fidelity Small Cap Index | 824.27K (1.18%) | 3.37K Increased by +0.41% | Oct 31, 24 |
| 19 | Fidelity Select Pharmaceuticals Port | 788.70K (1.13%) | -137.10K Decreased by -17.38% | Oct 31, 24 |
| 20 | Fidelity Select Biotechnology | 788.47K (1.13%) | 150.88K Increased by +19.14% | Nov 30, 24 |