| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 8.00M (8.20%) | -1.03M Decreased by -12.88% | Dec 31, 24 |
| 2 | BlackRock Inc | 7.95M (8.15%) | 155.29K Increased by +1.95% | Dec 31, 24 |
| 3 | HHG PLC | 7.38M (7.57%) | 566.15K Increased by +7.67% | Dec 31, 24 |
| 4 | Vanguard Group Inc | 6.70M (6.88%) | -160.21K Decreased by -2.39% | Dec 31, 24 |
| 5 | RA Capital Management, LLC | 6.38M (6.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | FCPM III SERVICES BV | 5.46M (5.60%) | -491.22K Decreased by -8.99% | Dec 31, 24 |
| 7 | RTW INVESTMENTS, LLC | 5.22M (5.35%) | -1.60M Decreased by -30.66% | Dec 31, 24 |
| 8 | State Street Corporation | 4.19M (4.30%) | 1.86M Increased by +44.27% | Mar 31, 24 |
| 9 | State Street Corp | 3.72M (3.81%) | 75.52K Increased by +2.03% | Dec 31, 24 |
| 10 | Citadel Advisors Llc | 2.86M (2.93%) | -77.76K Decreased by -2.72% | Dec 31, 24 |
| 11 | TCG Crossover Management, LLC | 2.65M (2.72%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | T. Rowe Price Associates, Inc. | 2.40M (2.46%) | -233.84K Decreased by -9.73% | Dec 31, 24 |
| 13 | Holocene Advisors, LP | 2.35M (2.41%) | 365.52K Increased by +15.57% | Dec 31, 24 |
| 14 | VR Adviser, LLC | 2.17M (2.23%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Vida Ventures Advisors, LLC | 2.07M (2.13%) | -145.25K Decreased by -7.00% | Dec 31, 23 |
| 16 | Morgan Stanley - Brokerage Accounts | 2.02M (2.07%) | 1.91M Increased by +94.67% | Dec 31, 23 |
| 17 | Deep Track Capital, LP | 2.00M (2.05%) | -1.28M Decreased by -64.10% | Dec 31, 24 |
| 18 | Adage Capital Partners Gp LLC | 1.95M (2.00%) | -452.97K Decreased by -23.23% | Dec 31, 24 |
| 19 | Geode Capital Management, LLC | 1.89M (1.94%) | 27.92K Increased by +1.48% | Dec 31, 24 |
| 20 | BRAIDWELL LP | 1.82M (1.87%) | 444.10K Increased by +24.37% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.08M (3.16%) | 442.20K Increased by +14.37% | Mar 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.65M (2.72%) | 2.40K Increased by +0.09% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 2.06M (2.11%) | 347.00 Increased by +0.02% | Apr 30, 25 |
| 4 | Fidelity Growth Compy Commingled Pl S | 1.84M (1.88%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Janus Henderson Global Life Sciences D | 1.79M (1.84%) | 71.81K Increased by +4.01% | Feb 28, 25 |
| 6 | Fidelity Growth Compy Commingled Pl O | 1.79M (1.83%) | 348.61K Increased by +19.51% | Aug 31, 24 |
| 7 | SPDR® S&P Biotech ETF | 1.76M (1.80%) | -30.79K Decreased by -1.75% | Apr 30, 25 |
| 8 | Janus Henderson Glb Life Scn I2 USD | 1.43M (1.47%) | -31.46K Decreased by -2.20% | Mar 31, 25 |
| 9 | Janus Henderson Global Life Sciences | 1.41M (1.45%) | -12.05K Decreased by -0.85% | Dec 31, 24 |
| 10 | Fidelity Growth Company Fund | 1.30M (1.33%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 1.23M (1.27%) | 31.97K Increased by +2.59% | Mar 31, 25 |
| 12 | Vanguard Small Cap Index | 1.20M (1.23%) | 159.13K Increased by +13.28% | Mar 31, 25 |
| 13 | Janus Global Life Science AUSD | 1.13M (1.15%) | 66.01K Increased by +5.87% | Dec 31, 24 |
| 14 | RTW Biotech Opportunities Ord | 1.11M (1.14%) | 1.11M Increased by +100.00% | Jun 30, 24 |
| 15 | JPMorgan Small Cap Growth A | 1.08M (1.11%) | 94.33K Increased by +8.73% | Mar 31, 25 |
| 16 | T. Rowe Price New Horizons | 900.31K (0.92%) | -12.18K Decreased by -1.35% | Mar 31, 25 |
| 17 | US Small-Cap Growth II Equity Comp | 900.31K (0.92%) | -83.74K Decreased by -9.30% | Mar 31, 25 |
| 18 | Janus Selection Global Life Science AUSD | 870.12K (0.89%) | 375.63K Increased by +43.17% | Jun 30, 24 |
| 19 | T. Rowe Price Health Sciences | 854.39K (0.88%) | -38.53K Decreased by -4.51% | Aug 31, 24 |
| 20 | Fidelity Small Cap Index | 819.16K (0.84%) | 6.16K Increased by +0.75% | Feb 28, 25 |