| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 10.35M (8.44%) | 2.97M Increased by +28.73% | Mar 31, 25 |
| 2 | RA Capital Management, LLC | 9.71M (7.92%) | 3.33M Increased by +34.31% | Mar 31, 25 |
| 3 | BlackRock Inc | 8.05M (6.56%) | 97.54K Increased by +1.21% | Mar 31, 25 |
| 4 | Vanguard Group Inc | 7.41M (6.04%) | 702.42K Increased by +9.48% | Mar 31, 25 |
| 5 | FCPM III SERVICES BV | 5.46M (4.45%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | FMR Inc | 5.20M (4.24%) | -2.80M Decreased by -53.93% | Mar 31, 25 |
| 7 | State Street Corporation | 4.19M (3.42%) | 1.86M Increased by +44.27% | Mar 31, 24 |
| 8 | BRAIDWELL LP | 3.62M (2.95%) | 2.94M Increased by +81.19% | Mar 31, 25 |
| 9 | State Street Corp | 3.61M (2.94%) | -107.73K Decreased by -2.98% | Mar 31, 25 |
| 10 | Citadel Advisors Llc | 3.01M (2.45%) | 147.81K Increased by +4.91% | Mar 31, 25 |
| 11 | Armistice Capital, LLC | 2.77M (2.26%) | 1.80M Increased by +65.15% | Mar 31, 25 |
| 12 | Siren, L.L.C. | 2.72M (2.22%) | 1.37M Increased by +50.42% | Mar 31, 25 |
| 13 | TCG Crossover Management, LLC | 2.65M (2.16%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 14 | JPMorgan Chase & Co | 2.53M (2.06%) | 2.43M Increased by +96.11% | Mar 31, 25 |
| 15 | Holocene Advisors, LP | 2.35M (1.91%) | 365.52K Increased by +15.57% | Dec 31, 24 |
| 16 | Perceptive Advisors LLC | 2.31M (1.89%) | 1.77M Increased by +76.52% | Mar 31, 25 |
| 17 | VR Adviser, LLC | 2.17M (1.77%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Vida Ventures Advisors, LLC | 2.07M (1.69%) | -145.25K Decreased by -7.00% | Dec 31, 23 |
| 19 | Morgan Stanley - Brokerage Accounts | 2.02M (1.65%) | 1.91M Increased by +94.67% | Dec 31, 23 |
| 20 | Deep Track Capital, LP | 2.00M (1.63%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.08M (2.51%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.65M (2.16%) | 2.40K Increased by +0.09% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 2.19M (1.79%) | -41.69K Decreased by -1.90% | Jul 31, 25 |
| 4 | Janus Henderson Global Life Sciences | 1.89M (1.54%) | 124.72K Increased by +6.61% | Jun 30, 25 |
| 5 | Fidelity Growth Compy Commingled Pl S | 1.84M (1.50%) | -831.00 Decreased by -0.05% | Jun 30, 25 |
| 6 | Janus Henderson Global Life Sciences D | 1.81M (1.47%) | -5.14K Decreased by -0.28% | May 31, 25 |
| 7 | Fidelity Growth Compy Commingled Pl O | 1.79M (1.46%) | 348.61K Increased by +19.51% | Aug 31, 24 |
| 8 | Janus Global Life Science AUSD | 1.55M (1.27%) | 121.81K Increased by +7.84% | Jun 30, 25 |
| 9 | Janus Henderson Glb Life Scn I2 USD | 1.55M (1.27%) | 91.50K Increased by +5.89% | Jun 30, 25 |
| 10 | Fidelity Select Biotechnology | 1.53M (1.24%) | -151.40K Decreased by -9.92% | Jun 30, 25 |
| 11 | JPMorgan Small Cap Growth A | 1.45M (1.18%) | 375.33K Increased by +25.96% | Jun 30, 25 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 1.39M (1.13%) | 144.60K Increased by +10.40% | Jun 30, 25 |
| 13 | SPDR® S&P Biotech ETF | 1.34M (1.10%) | 40.20K Increased by +2.99% | Jul 31, 25 |
| 14 | Fidelity Growth Company Fund | 1.30M (1.06%) | -1.50K Decreased by -0.12% | Jun 30, 25 |
| 15 | Vanguard Small Cap Index | 1.18M (0.96%) | -37.74K Decreased by -3.20% | Jun 30, 25 |
| 16 | T. Rowe Price New Horizons | 1.12M (0.91%) | -5.57K Decreased by -0.50% | Jun 30, 25 |
| 17 | US Small-Cap Growth II Equity Comp | 1.12M (0.91%) | 219.42K Increased by +19.60% | Jun 30, 25 |
| 18 | RTW Biotech Opportunities Ord | 1.11M (0.91%) | 1.11M Increased by +100.00% | Jun 30, 24 |
| 19 | T. Rowe Price Small-Cap Value | 1.01M (0.82%) | 170.22K Increased by +16.88% | Jun 30, 25 |
| 20 | Biotech Growth Ord | 899.48K (0.73%) | 467.06K Increased by +51.93% | Apr 30, 25 |