| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 13.70M (19.04%) | 812.98K Increased by +5.93% | Mar 31, 25 |
| 2 | BlackRock Inc | 6.76M (9.39%) | 602.09K Increased by +8.91% | Mar 31, 25 |
| 3 | Vanguard Group Inc | 5.94M (8.26%) | 94.32K Increased by +1.59% | Mar 31, 25 |
| 4 | RA Capital Management, LLC | 5.76M (8.00%) | -2.12M Decreased by -36.77% | Dec 31, 24 |
| 5 | Alyeska Investment Group, L.P. | 4.06M (5.64%) | 1.55M Increased by +38.12% | Mar 31, 25 |
| 6 | Franklin Resources Inc | 4.02M (5.59%) | 135.42K Increased by +3.37% | Mar 31, 25 |
| 7 | Pictet Asset Manangement SA | 3.64M (5.05%) | 145.52K Increased by +4.00% | Mar 31, 25 |
| 8 | BRAIDWELL LP | 3.54M (4.92%) | -1.34M Decreased by -37.80% | Mar 31, 25 |
| 9 | State Street Corporation | 3.38M (4.70%) | 444.18K Increased by +13.14% | Dec 31, 23 |
| 10 | Estuary Capital Management, LP | 3.33M (4.62%) | -389.93K Decreased by -11.72% | Mar 31, 25 |
| 11 | Fairmount Funds Management LLC | 3.10M (4.31%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | Deerfield Management Co | 2.96M (4.12%) | 364.71K Increased by +12.32% | Mar 31, 25 |
| 13 | State Street Corp | 2.71M (3.76%) | -394.98K Decreased by -14.59% | Mar 31, 25 |
| 14 | Viking Global Investors LP | 2.56M (3.56%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Canaan Partners XI LLC | 2.49M (3.46%) | -56.84K Decreased by -2.28% | Sep 30, 23 |
| 16 | Polar Capital Holdings PLC | 2.35M (3.27%) | 2.17M Increased by +92.13% | Mar 31, 25 |
| 17 | Partner Fund Management LP | 2.22M (3.09%) | 1.08M Increased by +48.43% | Sep 30, 23 |
| 18 | Wagonhound Investments, LP | 2.19M (3.04%) | -48.46K Decreased by -2.21% | Sep 30, 23 |
| 19 | Maverick Capital Ltd | 2.11M (2.94%) | 902.87K Increased by +42.71% | Sep 30, 24 |
| 20 | TimesSquare Capital Management, LLC | 1.71M (2.38%) | -116.77K Decreased by -6.82% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 2.46M (3.42%) | 522.40K Increased by +21.25% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.40M (3.34%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 3 | Pictet-Biotech P USD | 2.32M (3.23%) | 264.60K Increased by +11.39% | Jan 31, 25 |
| 4 | Polar Capital Biotech S Inc | 2.00M (2.78%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Fidelity Small Cap Growth | 1.59M (2.21%) | 270.50K Increased by +16.99% | Feb 28, 25 |
| 6 | Franklin Biotechnology Discv A(acc)USD | 1.49M (2.08%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 7 | Franklin Small Cap Growth Adv | 1.48M (2.06%) | -12.32K Decreased by -0.83% | Mar 31, 25 |
| 8 | Franklin US Small Cap Growth Equity | 1.48M (2.06%) | 86.88K Increased by +5.86% | Mar 31, 25 |
| 9 | SPDR® S&P Biotech ETF | 1.42M (1.98%) | -20.84K Decreased by -1.46% | Apr 30, 25 |
| 10 | Pictet Biotech | 1.37M (1.91%) | 1.37M Increased by +100.00% | Mar 31, 24 |
| 11 | FIAM Small Cap Core CIT Cl B | 1.33M (1.85%) | -31.70K Decreased by -2.38% | Feb 28, 25 |
| 12 | iShares Russell 2000 ETF | 1.32M (1.84%) | 223.00 Increased by +0.02% | Apr 30, 25 |
| 13 | FIAM Small Cap Core Composite | 1.24M (1.73%) | 1.24M Increased by +100.00% | Dec 31, 24 |
| 14 | Franklin Small Cap Growth SMA | 1.17M (1.63%) | 1.17M Increased by +99.99% | Mar 31, 24 |
| 15 | US Small-Cap Growth II Equity Comp | 1.14M (1.59%) | -397.68K Decreased by -34.74% | Dec 31, 24 |
| 16 | Fidelity Growth Compy Commingled Pl S | 1.14M (1.58%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Pictet-Global Megatrend Sel I USD | 1.07M (1.48%) | -130.34K Decreased by -12.21% | Jan 31, 25 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 1.06M (1.48%) | 1.98K Increased by +0.19% | Apr 30, 25 |
| 19 | Fidelity Select Health Care | 1.00M (1.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | T. Rowe Price New Horizons | 980.72K (1.36%) | 0.00 Increased by 0.00% | Feb 28, 25 |