| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 13.70M (18.85%) | 812.98K Increased by +5.93% | Mar 31, 25 |
| 2 | BlackRock Inc | 6.76M (9.30%) | 602.09K Increased by +8.91% | Mar 31, 25 |
| 3 | Vanguard Group Inc | 5.94M (8.18%) | 94.32K Increased by +1.59% | Mar 31, 25 |
| 4 | RA Capital Management, LLC | 5.76M (7.92%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Alyeska Investment Group, L.P. | 4.06M (5.58%) | 1.55M Increased by +38.12% | Mar 31, 25 |
| 6 | Franklin Resources Inc | 4.02M (5.53%) | 135.42K Increased by +3.37% | Mar 31, 25 |
| 7 | Pictet Asset Manangement SA | 3.64M (5.00%) | 145.52K Increased by +4.00% | Mar 31, 25 |
| 8 | BRAIDWELL LP | 3.54M (4.86%) | -1.34M Decreased by -37.80% | Mar 31, 25 |
| 9 | State Street Corporation | 3.38M (4.65%) | 444.18K Increased by +13.14% | Dec 31, 23 |
| 10 | Estuary Capital Management, LP | 3.33M (4.58%) | -389.93K Decreased by -11.72% | Mar 31, 25 |
| 11 | Fairmount Funds Management LLC | 3.10M (4.27%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | Deerfield Management Co | 2.96M (4.07%) | 364.71K Increased by +12.32% | Mar 31, 25 |
| 13 | State Street Corp | 2.71M (3.72%) | -394.98K Decreased by -14.59% | Mar 31, 25 |
| 14 | Vestal Point Capital LP | 2.60M (3.57%) | 1.16M Increased by +44.58% | Mar 31, 25 |
| 15 | Viking Global Investors LP | 2.56M (3.52%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | Canaan Partners XI LLC | 2.49M (3.43%) | -56.84K Decreased by -2.28% | Sep 30, 23 |
| 17 | Polar Capital Holdings PLC | 2.35M (3.23%) | 2.17M Increased by +92.13% | Mar 31, 25 |
| 18 | Partner Fund Management LP | 2.22M (3.06%) | 1.08M Increased by +48.43% | Sep 30, 23 |
| 19 | Wagonhound Investments, LP | 2.19M (3.01%) | -48.46K Decreased by -2.21% | Sep 30, 23 |
| 20 | Maverick Capital Ltd | 2.11M (2.91%) | 902.87K Increased by +42.71% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 2.46M (3.38%) | 522.40K Increased by +21.25% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.44M (3.36%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Pictet-Biotech P USD | 2.22M (3.05%) | -37.80K Decreased by -1.70% | Apr 30, 25 |
| 4 | Polar Capital Biotech S Inc | 2.11M (2.90%) | 134.18K Increased by +6.36% | Jun 30, 25 |
| 5 | iShares Russell 2000 ETF | 1.69M (2.33%) | -27.39K Decreased by -1.62% | Jul 30, 25 |
| 6 | Franklin Small Cap Growth SMA | 1.61M (2.22%) | 1.61M Increased by +99.99% | Jun 30, 25 |
| 7 | Franklin US Small Cap Growth Equity | 1.61M (2.22%) | 130.60K Increased by +8.10% | Jun 30, 25 |
| 8 | Fidelity Small Cap Growth | 1.59M (2.18%) | -4.22K Decreased by -0.27% | May 31, 25 |
| 9 | Franklin Biotechnology Discv A(acc)USD | 1.55M (2.14%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Franklin Small Cap Growth Adv | 1.48M (2.04%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Pictet Biotech | 1.37M (1.89%) | 1.37M Increased by +100.00% | Mar 31, 24 |
| 12 | FIAM Small Cap Core Composite | 1.33M (1.83%) | 89.60K Increased by +6.73% | Mar 31, 25 |
| 13 | FIAM Small Cap Core CIT Cl B | 1.30M (1.79%) | -11.10K Decreased by -0.85% | May 31, 25 |
| 14 | SPDR® S&P Biotech ETF | 1.20M (1.65%) | 29.54K Increased by +2.47% | Jul 31, 25 |
| 15 | Pictet-Global Megatrend Sel I USD | 1.15M (1.58%) | 100.75K Increased by +8.76% | Apr 30, 25 |
| 16 | US Small-Cap Growth II Equity Comp | 1.14M (1.57%) | -397.68K Decreased by -34.74% | Dec 31, 24 |
| 17 | Fidelity Growth Compy Commingled Pl S | 1.14M (1.56%) | 1.53K Increased by +0.13% | Jun 30, 25 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 1.08M (1.48%) | 5.23K Increased by +0.49% | Jun 30, 25 |
| 19 | BlackRock Advantage Small Cap Core Instl | 1.05M (1.44%) | 593.17K Increased by +56.61% | Jun 30, 25 |
| 20 | Fidelity Select Health Care | 1.00M (1.38%) | 0.00 Increased by 0.00% | Jun 30, 25 |