| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 12.89M (17.91%) | 5.48M Increased by +42.48% | Dec 31, 24 |
| 2 | BlackRock Inc | 6.16M (8.55%) | 1.45M Increased by +23.50% | Dec 31, 24 |
| 3 | Vanguard Group Inc | 5.85M (8.13%) | -38.29K Decreased by -0.65% | Dec 31, 24 |
| 4 | RA Capital Management, LLC | 5.76M (8.00%) | -2.12M Decreased by -36.77% | Dec 31, 24 |
| 5 | BRAIDWELL LP | 4.87M (6.77%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | Franklin Resources Inc | 3.88M (5.40%) | 13.32K Increased by +0.34% | Dec 31, 24 |
| 7 | Estuary Capital Management, LP | 3.72M (5.16%) | 973.00K Increased by +26.18% | Dec 31, 24 |
| 8 | Pictet Asset Manangement SA | 3.49M (4.85%) | 507.40K Increased by +14.54% | Dec 31, 24 |
| 9 | State Street Corporation | 3.38M (4.70%) | 444.18K Increased by +13.14% | Dec 31, 23 |
| 10 | Fairmount Funds Management LLC | 3.10M (4.31%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | State Street Corp | 3.10M (4.31%) | 277.86K Increased by +8.96% | Dec 31, 24 |
| 12 | Deerfield Management Co | 2.60M (3.61%) | -21.68K Decreased by -0.84% | Dec 31, 24 |
| 13 | Viking Global Investors LP | 2.56M (3.55%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Alyeska Investment Group, L.P. | 2.51M (3.49%) | 2.51M Increased by +100.00% | Dec 31, 24 |
| 15 | Canaan Partners XI LLC | 2.49M (3.46%) | -56.84K Decreased by -2.28% | Sep 30, 23 |
| 16 | Partner Fund Management LP | 2.22M (3.09%) | 1.08M Increased by +48.43% | Sep 30, 23 |
| 17 | Wagonhound Investments, LP | 2.19M (3.04%) | -48.46K Decreased by -2.21% | Sep 30, 23 |
| 18 | Maverick Capital Ltd | 2.11M (2.94%) | 902.87K Increased by +42.71% | Sep 30, 24 |
| 19 | Goldman Sachs Group Inc | 1.77M (2.47%) | -128.80K Decreased by -7.26% | Sep 30, 24 |
| 20 | TimesSquare Capital Management, LLC | 1.71M (2.38%) | -116.77K Decreased by -6.82% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.40M (3.34%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 2 | Pictet-Biotech P USD | 2.06M (2.86%) | -3.79K Decreased by -0.18% | Dec 31, 24 |
| 3 | Polar Capital Biotech S Inc | 2.00M (2.78%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Franklin Small Cap Growth Adv | 1.49M (2.08%) | 99.20K Increased by +6.64% | Feb 28, 25 |
| 5 | Franklin Biotechnology Discv A(acc)USD | 1.49M (2.07%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 6 | SPDR® S&P Biotech ETF | 1.46M (2.03%) | -15.63K Decreased by -1.07% | Mar 31, 25 |
| 7 | iShares Russell 2000 ETF | 1.42M (1.97%) | -12.27K Decreased by -0.86% | Mar 31, 25 |
| 8 | Franklin US Small Cap Growth Equity | 1.40M (1.94%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | Pictet Biotech | 1.37M (1.91%) | 1.37M Increased by +100.00% | Mar 31, 24 |
| 10 | FIAM Small Cap Core CIT Cl B | 1.36M (1.89%) | 121.30K Increased by +8.90% | Jan 31, 25 |
| 11 | Fidelity Small Cap Growth | 1.32M (1.84%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 12 | FIAM Small Cap Core Composite | 1.24M (1.73%) | 1.24M Increased by +100.00% | Dec 31, 24 |
| 13 | Pictet-Global Megatrend Sel I USD | 1.20M (1.66%) | 2.88K Increased by +0.24% | Dec 31, 24 |
| 14 | Franklin Small Cap Growth SMA | 1.17M (1.63%) | 1.17M Increased by +99.99% | Mar 31, 24 |
| 15 | US Small-Cap Growth II Equity Comp | 1.14M (1.59%) | -397.68K Decreased by -34.74% | Dec 31, 24 |
| 16 | Fidelity Growth Compy Commingled Pl S | 1.14M (1.58%) | 3.13K Increased by +0.28% | Feb 28, 25 |
| 17 | Vanguard Institutional Extnd Mkt Idx Tr | 1.03M (1.43%) | 1.81K Increased by +0.18% | Feb 28, 25 |
| 18 | Fidelity Select Health Care | 1.00M (1.39%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 19 | T. Rowe Price New Horizons | 980.72K (1.36%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 20 | Vanguard Small Cap Index | 962.73K (1.34%) | 781.00 Increased by +0.08% | Feb 28, 25 |