| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 11.34M (15.39%) | -2.36M Decreased by -20.79% | Jun 30, 25 |
| 2 | BlackRock Inc | 9.83M (13.34%) | 3.07M Increased by +31.26% | Jun 30, 25 |
| 3 | Vanguard Group Inc | 6.18M (8.38%) | 233.25K Increased by +3.78% | Jun 30, 25 |
| 4 | RA Capital Management, LLC | 5.76M (7.81%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Franklin Resources Inc | 4.10M (5.56%) | 79.25K Increased by +1.93% | Jun 30, 25 |
| 6 | Deerfield Management Co | 3.72M (5.05%) | 762.39K Increased by +20.48% | Jun 30, 25 |
| 7 | Pictet Asset Manangement SA | 3.72M (5.05%) | 87.15K Increased by +2.34% | Jun 30, 25 |
| 8 | State Street Corporation | 3.38M (4.59%) | 444.18K Increased by +13.14% | Dec 31, 23 |
| 9 | Estuary Capital Management, LP | 3.33M (4.51%) | -389.93K Decreased by -11.72% | Mar 31, 25 |
| 10 | Fairmount Funds Management LLC | 3.10M (4.21%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | Alyeska Investment Group, L.P. | 3.01M (4.09%) | -1.05M Decreased by -34.78% | Jun 30, 25 |
| 12 | Vestal Point Capital LP | 3.00M (4.07%) | 401.87K Increased by +13.40% | Jun 30, 25 |
| 13 | State Street Corp | 2.69M (3.65%) | -17.01K Decreased by -0.63% | Jun 30, 25 |
| 14 | Viking Global Investors LP | 2.56M (3.47%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Canaan Partners XI LLC | 2.49M (3.38%) | -56.84K Decreased by -2.28% | Sep 30, 23 |
| 16 | Partner Fund Management LP | 2.22M (3.02%) | 1.08M Increased by +48.43% | Sep 30, 23 |
| 17 | Wagonhound Investments, LP | 2.19M (2.97%) | -48.46K Decreased by -2.21% | Sep 30, 23 |
| 18 | BRAIDWELL LP | 2.18M (2.96%) | -1.36M Decreased by -62.12% | Jun 30, 25 |
| 19 | Maverick Capital Ltd | 2.11M (2.87%) | 902.87K Increased by +42.71% | Sep 30, 24 |
| 20 | Polar Capital Holdings PLC | 2.11M (2.86%) | -240.82K Decreased by -11.42% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 2.46M (3.34%) | 522.40K Increased by +21.25% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.39M (3.24%) | -52.94K Decreased by -2.22% | Jul 31, 25 |
| 3 | Pictet-Biotech P USD | 2.25M (3.05%) | 27.52K Increased by +1.22% | May 31, 25 |
| 4 | Polar Capital Biotech S Inc | 2.11M (2.86%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 5 | iShares Russell 2000 ETF | 1.70M (2.31%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | Franklin Small Cap Growth SMA | 1.61M (2.19%) | 1.61M Increased by +99.99% | Jun 30, 25 |
| 7 | Franklin US Small Cap Growth Equity | 1.61M (2.19%) | 130.60K Increased by +8.10% | Jun 30, 25 |
| 8 | Fidelity Small Cap Growth | 1.59M (2.15%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Franklin Biotechnology Discv A(acc)USD | 1.55M (2.11%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 10 | Franklin Small Cap Growth Adv | 1.48M (2.01%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | Pictet Biotech | 1.37M (1.86%) | 1.37M Increased by +100.00% | Mar 31, 24 |
| 12 | FIAM Small Cap Core Composite | 1.33M (1.81%) | 89.60K Increased by +6.73% | Mar 31, 25 |
| 13 | FIAM Small Cap Core CIT Cl B | 1.32M (1.79%) | 19.45K Increased by +1.47% | Jun 30, 25 |
| 14 | SPDR® S&P Biotech ETF | 1.20M (1.63%) | 2.69K Increased by +0.22% | Aug 31, 25 |
| 15 | Pictet-Global Megatrend Sel I USD | 1.17M (1.59%) | 17.86K Increased by +1.53% | May 31, 25 |
| 16 | US Small-Cap Growth II Equity Comp | 1.14M (1.55%) | -397.68K Decreased by -34.74% | Dec 31, 24 |
| 17 | Fidelity Growth Compy Commingled Pl S | 1.14M (1.55%) | 1.44K Increased by +0.13% | Jul 31, 25 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 1.08M (1.46%) | 5.23K Increased by +0.49% | Jun 30, 25 |
| 19 | Fidelity Select Health Care | 1.00M (1.36%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 20 | T. Rowe Price New Horizons | 980.72K (1.33%) | 0.00 Increased by 0.00% | Feb 28, 25 |