| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | TANG CAPITAL MANAGEMENT LLC | 6.72M (11.04%) | -593.93K Decreased by -8.84% | Mar 31, 25 |
| 2 | Bvf Inc | 5.23M (8.59%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Vanguard Group Inc | 5.12M (8.41%) | -44.93K Decreased by -0.88% | Mar 31, 25 |
| 4 | HHG PLC | 4.81M (7.90%) | -1.49M Decreased by -31.03% | Sep 30, 24 |
| 5 | Prosight Management, LP | 3.93M (6.46%) | 25.01K Increased by +0.64% | Mar 31, 25 |
| 6 | Orbimed Advisors, LLC | 3.54M (5.82%) | 3.54M Increased by +100.00% | Mar 31, 24 |
| 7 | Acadian Asset Management LLC | 3.23M (5.31%) | 3.20M Increased by +98.95% | Mar 31, 25 |
| 8 | Adage Capital Partners Gp LLC | 3.00M (4.93%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | Millennium Management LLC | 2.83M (4.64%) | -394.74K Decreased by -13.97% | Mar 31, 25 |
| 10 | Point72 Asset Management, L.P. | 2.65M (4.35%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Woodline Partners LP | 1.66M (2.72%) | 1.66M Increased by +100.00% | Mar 31, 25 |
| 12 | Sio Capital Management, LLC | 1.60M (2.63%) | 1.60M Increased by +100.00% | Mar 31, 24 |
| 13 | Schonfeld Strategic Advisors LLC | 1.38M (2.27%) | 169.00K Increased by +12.24% | Dec 31, 24 |
| 14 | LAURION CAPITAL MANAGEMENT LP | 1.29M (2.13%) | 45.32K Increased by +3.50% | Mar 31, 25 |
| 15 | RTW INVESTMENTS, LLC | 1.20M (1.97%) | 1.20M Increased by +100.00% | Jun 30, 24 |
| 16 | BlackRock Inc | 1.17M (1.92%) | -73.39K Decreased by -6.29% | Mar 31, 25 |
| 17 | Renaissance Technologies Corp | 1.16M (1.90%) | -190.80K Decreased by -16.51% | Mar 31, 25 |
| 18 | SUPERSTRING CAPITAL MANAGEMENT LP | 1.15M (1.89%) | 472.12K Increased by +41.00% | Jun 30, 24 |
| 19 | RA Capital Management, LLC | 1.00M (1.64%) | 1.00M Increased by +100.00% | Mar 31, 25 |
| 20 | Susquehanna International Group, LLP | 936.78K (1.54%) | 897.79K Increased by +95.84% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Franklin Biotechnology Discv A(acc)USD | 3.72M (6.12%) | 3.72M Increased by +100.00% | May 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.46M (4.03%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 2.46M (4.03%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Biotech Growth Ord | 1.69M (2.77%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 982.29K (1.61%) | 800.00 Increased by +0.08% | Apr 30, 25 |
| 6 | Vanguard Explorer Inv | 820.46K (1.35%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Vanguard Strategic Small-Cap Equity Inv | 555.12K (0.91%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | Acadian Global Small-Cap Equity CIT Cl A | 487.90K (0.80%) | 0.00 Increased by 0.00% | Mar 4, 25 |
| 9 | Fidelity Extended Market Index | 444.97K (0.73%) | -4.25K Decreased by -0.96% | Apr 30, 25 |
| 10 | Fidelity Blue Chip Growth | 378.62K (0.62%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 11 | Fidelity® Blue Chip Growth | 378.62K (0.62%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 12 | Fidelity® Extended Market Index | 350.14K (0.58%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 13 | Formidable ETF | 312.85K (0.51%) | 0.00 Increased by 0.00% | May 30, 25 |
| 14 | iShares Core S&P Total US Stock Mkt ETF | 266.72K (0.44%) | 0.00 Increased by 0.00% | May 31, 25 |
| 15 | BIT Biotech Opportunities S | 250.91K (0.41%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 16 | Vanguard VIF Small Co Gr | 235.81K (0.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Belfius Equities Cure C Cap | 210.00K (0.35%) | -190.00K Decreased by -90.48% | Jun 30, 24 |
| 18 | Candriam Global Equities Oncology | 210.00K (0.35%) | 210.00K Increased by +100.00% | Jun 30, 24 |
| 19 | A4Investments SICAV SIF ACCI IlanaA2EURH | 200.00K (0.33%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 20 | Fidelity Enhanced Small Cap ETF | 195.47K (0.32%) | 0.00 Increased by 0.00% | Feb 28, 25 |