| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 14.03M (15.20%) | 5.10M Increased by +36.37% | Mar 31, 25 |
| 2 | Vanguard Group Inc | 9.31M (10.09%) | 222.21K Increased by +2.39% | Mar 31, 25 |
| 3 | BlackRock Inc | 7.66M (8.30%) | 141.38K Increased by +1.85% | Mar 31, 25 |
| 4 | Wellington Management Company LLP | 6.89M (7.47%) | -59.17K Decreased by -0.86% | Mar 31, 25 |
| 5 | Driehaus Capital Management LLC | 6.24M (6.76%) | 98.89K Increased by +1.58% | Mar 31, 25 |
| 6 | T. Rowe Price Associates, Inc. | 5.11M (5.54%) | -302.14K Decreased by -5.91% | Mar 31, 25 |
| 7 | Farallon Capital Management, L.L.C. | 4.61M (4.99%) | 530.00K Increased by +11.51% | Mar 31, 25 |
| 8 | EcoR1 Capital, LLC | 4.29M (4.65%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | HHG PLC | 3.42M (3.71%) | 629.00K Increased by +18.37% | Mar 31, 25 |
| 10 | State Street Corp | 3.28M (3.56%) | 292.44K Increased by +8.91% | Mar 31, 25 |
| 11 | State Street Corporation | 3.26M (3.53%) | -308.48K Decreased by -9.48% | Mar 31, 24 |
| 12 | Point72 Asset Management, L.P. | 2.79M (3.02%) | 488.30K Increased by +17.51% | Dec 31, 24 |
| 13 | Geode Capital Management, LLC | 2.19M (2.37%) | 92.09K Increased by +4.20% | Mar 31, 25 |
| 14 | Jennison Associates LLC | 2.12M (2.30%) | -588.58K Decreased by -27.77% | Mar 31, 25 |
| 15 | Paradigm Biocapital Advisors LP | 1.95M (2.11%) | 35.41K Increased by +1.82% | Mar 31, 25 |
| 16 | Siren, L.L.C. | 1.69M (1.83%) | 78.96K Increased by +4.68% | Mar 31, 25 |
| 17 | Morgan Stanley - Brokerage Accounts | 1.68M (1.82%) | 452.85K Increased by +27.00% | Jun 30, 24 |
| 18 | Perceptive Advisors LLC | 1.48M (1.60%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 19 | Goldman Sachs Group Inc | 1.30M (1.41%) | 747.75K Increased by +57.50% | Dec 31, 23 |
| 20 | Bain Capital Life Sciences Investors, LLC | 1.28M (1.38%) | -1.03M Decreased by -80.75% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.99M (3.24%) | 11.40K Increased by +0.38% | Apr 30, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.40M (2.60%) | 2.45K Increased by +0.10% | Sep 30, 24 |
| 3 | Vanguard Small Cap Index | 2.33M (2.52%) | 11.78K Increased by +0.51% | Apr 30, 25 |
| 4 | Vanguard Health Care Inv | 2.28M (2.48%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | iShares Russell 2000 ETF | 2.26M (2.45%) | 381.00 Increased by +0.02% | Apr 30, 25 |
| 6 | T. Rowe Price New Horizons | 2.11M (2.29%) | -28.60K Decreased by -1.35% | Mar 31, 25 |
| 7 | US Small-Cap Growth II Equity Comp | 2.11M (2.29%) | -29.22K Decreased by -1.38% | Mar 31, 25 |
| 8 | Fidelity OTC | 1.66M (1.80%) | 1.66M Increased by +100.00% | Mar 31, 25 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 1.43M (1.55%) | 5.62K Increased by +0.39% | Apr 30, 25 |
| 10 | Vanguard Small Cap Growth Index Inv | 1.30M (1.41%) | -977.00 Decreased by -0.08% | Apr 30, 25 |
| 11 | T. Rowe Price Integrated US SmCapGrEq | 1.28M (1.39%) | 722.20K Increased by +56.36% | Dec 31, 24 |
| 12 | Fidelity Select Health Care | 1.28M (1.39%) | 280.00K Increased by +21.88% | Mar 31, 25 |
| 13 | Fidelity® Select Biotechnology | 1.23M (1.34%) | -136.40K Decreased by -11.06% | Nov 30, 23 |
| 14 | SPDR® S&P Biotech ETF | 1.22M (1.32%) | -17.90K Decreased by -1.47% | Apr 30, 25 |
| 15 | Vanguard Explorer Inv | 1.08M (1.17%) | 105.64K Increased by +9.75% | Mar 31, 25 |
| 16 | PGIM Jennison Health Sciences Z | 1.05M (1.14%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Bridge Builder Small/Mid Cap Growth | 1.01M (1.10%) | -4.77K Decreased by -0.47% | Apr 30, 25 |
| 18 | Fidelity Select Biotechnology | 942.20K (1.02%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | T. Rowe Price Health Sciences | 922.48K (1.00%) | -50.48K Decreased by -5.47% | Mar 31, 25 |
| 20 | MEDICAL BioHealth EUR Acc | 921.76K (1.00%) | 109.00K Increased by +11.83% | Jan 31, 25 |