| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 14.29M (14.85%) | 106.28K Increased by +0.74% | Dec 31, 25 |
| 2 | Vanguard Group Inc | 9.14M (9.49%) | -34.63K Decreased by -0.38% | Dec 31, 25 |
| 3 | Wellington Management Company LLP | 8.04M (8.35%) | -344.10K Decreased by -4.28% | Dec 31, 25 |
| 4 | BlackRock Inc | 7.59M (7.88%) | 167.88K Increased by +2.21% | Sep 30, 25 |
| 5 | Farallon Capital Management, L.L.C. | 6.93M (7.20%) | 1.16M Increased by +16.77% | Dec 31, 25 |
| 6 | Driehaus Capital Management LLC | 6.39M (6.64%) | -93.87K Decreased by -1.47% | Dec 31, 25 |
| 7 | T. Rowe Price Associates, Inc. | 5.31M (5.51%) | -284.26K Decreased by -5.36% | Sep 30, 25 |
| 8 | EcoR1 Capital, LLC | 4.29M (4.46%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 9 | HHG PLC | 3.86M (4.01%) | 448.47K Increased by +11.62% | Sep 30, 25 |
| 10 | State Street Corporation | 3.26M (3.38%) | -308.48K Decreased by -9.48% | Mar 31, 24 |
| 11 | JPMorgan Chase & Co | 2.52M (2.62%) | 2.19M Increased by +86.81% | Sep 30, 25 |
| 12 | Point72 Asset Management, L.P. | 2.34M (2.43%) | 333.70K Increased by +14.28% | Dec 31, 25 |
| 13 | Geode Capital Management, LLC | 2.24M (2.33%) | -36.20K Decreased by -1.61% | Dec 31, 25 |
| 14 | Paradigm Biocapital Advisors LP | 2.21M (2.30%) | -340.00K Decreased by -15.38% | Dec 31, 25 |
| 15 | State Street Corp | 2.21M (2.29%) | -1.02M Decreased by -46.05% | Sep 30, 25 |
| 16 | Morgan Stanley - Brokerage Accounts | 1.68M (1.74%) | 452.85K Increased by +27.00% | Jun 30, 24 |
| 17 | Baker Bros Advisors LP | 1.65M (1.71%) | 1.37M Increased by +83.02% | Dec 31, 25 |
| 18 | Novo A/S | 1.63M (1.69%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 19 | Pictet Asset Manangement SA | 1.56M (1.62%) | 95.04K Increased by +6.09% | Dec 31, 25 |
| 20 | Siren, L.L.C. | 1.51M (1.57%) | -180.97K Decreased by -12.00% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.24M (3.36%) | 7.51K Increased by +0.23% | Feb 28, 26 |
| 2 | Vanguard Health Care Inv | 3.19M (3.31%) | -408.52K Decreased by -12.81% | Dec 31, 25 |
| 3 | Fidelity OTC | 2.73M (2.84%) | 28.50K Increased by +1.04% | Feb 28, 26 |
| 4 | Vanguard US Total Market Shares ETF | 2.40M (2.50%) | 2.45K Increased by +0.10% | Sep 30, 24 |
| 5 | iShares Russell 2000 ETF | 2.37M (2.46%) | -19.36K Decreased by -0.82% | Mar 31, 26 |
| 6 | Vanguard Small Cap Index | 2.33M (2.42%) | 6.89K Increased by +0.30% | Feb 28, 26 |
| 7 | T. Rowe Price New Horizons | 1.58M (1.64%) | 89.61K Increased by +5.67% | Jan 31, 26 |
| 8 | US Small-Cap Growth II Equity Comp | 1.49M (1.55%) | -178.66K Decreased by -11.97% | Dec 31, 25 |
| 9 | T. Rowe Price Health Sciences | 1.30M (1.35%) | 123.13K Increased by +9.51% | Jan 31, 26 |
| 10 | Vanguard Small Cap Growth Index Inv | 1.29M (1.34%) | 4.20K Increased by +0.33% | Feb 28, 26 |
| 11 | Fidelity Select Health Care | 1.28M (1.33%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 12 | Fidelity® Select Biotechnology | 1.23M (1.28%) | -136.40K Decreased by -11.06% | Nov 30, 23 |
| 13 | Vanguard Explorer Inv | 1.12M (1.16%) | 138.45K Increased by +12.37% | Dec 31, 25 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 1.12M (1.16%) | 12.03K Increased by +1.08% | Feb 28, 26 |
| 15 | SPDR® S&P Biotech ETF | 1.11M (1.15%) | 2.47K Increased by +0.22% | Aug 31, 25 |
| 16 | PGIM Jennison Health Sciences Z | 1.05M (1.09%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Pictet-Biotech P USD | 993.55K (1.03%) | 90.62K Increased by +9.12% | Dec 31, 25 |
| 18 | Bridge Builder Small/Mid Cap Growth | 965.64K (1.00%) | 16.12K Increased by +1.67% | Mar 31, 26 |
| 19 | Fidelity Small Cap Index | 946.64K (0.98%) | 59.73K Increased by +6.31% | Jan 31, 26 |
| 20 | Fidelity Small Cap Growth | 938.59K (0.98%) | 49.40K Increased by +5.26% | Jan 31, 26 |