| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 15.76M (16.49%) | 1.47M Increased by +9.30% | Mar 31, 26 |
| 2 | Vanguard Group Inc | 9.14M (9.56%) | -34.63K Decreased by -0.38% | Dec 31, 25 |
| 3 | BlackRock Inc | 8.48M (8.87%) | 490.27K Increased by +5.78% | Mar 31, 26 |
| 4 | Farallon Capital Management, L.L.C. | 8.34M (8.73%) | 1.41M Increased by +16.85% | Mar 31, 26 |
| 5 | Wellington Management Company LLP | 8.16M (8.54%) | 119.31K Increased by +1.46% | Mar 31, 26 |
| 6 | Driehaus Capital Management LLC | 6.40M (6.69%) | 8.18K Increased by +0.13% | Mar 31, 26 |
| 7 | T. Rowe Price Associates, Inc. | 5.36M (5.61%) | 131.11K Increased by +2.45% | Mar 31, 26 |
| 8 | Vanguard Capital Management, LLC | 4.67M (4.89%) | 4.67M Increased by +100.00% | Mar 31, 26 |
| 9 | Vanguard Portfolio Management, LLC | 4.64M (4.85%) | 4.64M Increased by +100.00% | Mar 31, 26 |
| 10 | HHG PLC | 4.52M (4.73%) | 79.56K Increased by +1.76% | Mar 31, 26 |
| 11 | EcoR1 Capital, LLC | 4.29M (4.49%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | Bellevue Group AG | 3.28M (3.43%) | 3.28M Increased by +99.88% | Mar 31, 26 |
| 13 | State Street Corporation | 3.26M (3.41%) | -308.48K Decreased by -9.48% | Mar 31, 24 |
| 14 | Geode Capital Management, LLC | 2.48M (2.60%) | 238.13K Increased by +9.60% | Mar 31, 26 |
| 15 | State Street Corp | 2.40M (2.52%) | 241.67K Increased by +10.06% | Mar 31, 26 |
| 16 | Baker Bros Advisors LP | 2.35M (2.46%) | 702.60K Increased by +29.88% | Mar 31, 26 |
| 17 | Point72 Asset Management, L.P. | 2.34M (2.45%) | 333.70K Increased by +14.28% | Dec 31, 25 |
| 18 | Paradigm Biocapital Advisors LP | 2.21M (2.31%) | -340.00K Decreased by -15.38% | Dec 31, 25 |
| 19 | T. Rowe Price Investment Management,Inc. | 1.94M (2.03%) | 1.85M Increased by +95.45% | Mar 31, 26 |
| 20 | Siren, L.L.C. | 1.90M (1.99%) | 396.00K Increased by +20.80% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 3.49M (3.66%) | 306.20K Increased by +8.76% | Mar 31, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.36M (3.52%) | 11.62K Increased by +0.35% | Apr 30, 26 |
| 3 | Fidelity OTC | 3.03M (3.17%) | 20.80K Increased by +0.69% | Apr 30, 26 |
| 4 | Vanguard Small Cap Index | 2.41M (2.52%) | -8.48K Decreased by -0.35% | Apr 30, 26 |
| 5 | Vanguard US Total Market Shares ETF | 2.40M (2.51%) | 2.45K Increased by +0.10% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 2.33M (2.44%) | 21.53K Increased by +0.92% | May 29, 26 |
| 7 | Polar Capital Biotech S Inc | 2.27M (2.38%) | 2.27M Increased by +100.00% | Apr 30, 26 |
| 8 | US Small-Cap Growth II Equity Comp | 1.58M (1.66%) | 89.61K Increased by +5.67% | Mar 31, 26 |
| 9 | T. Rowe Price New Horizons | 1.58M (1.65%) | -709.00 Decreased by -0.04% | Apr 30, 26 |
| 10 | Vanguard Small Cap Growth Index Inv | 1.36M (1.42%) | 4.54K Increased by +0.33% | Apr 30, 26 |
| 11 | Fidelity Select Health Care | 1.28M (1.34%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 12 | Fidelity® Select Biotechnology | 1.23M (1.29%) | -136.40K Decreased by -11.06% | Nov 30, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 1.16M (1.21%) | 12.01K Increased by +1.04% | Apr 30, 26 |
| 14 | Vanguard Explorer Inv | 1.12M (1.17%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | SPDR® S&P Biotech ETF | 1.11M (1.16%) | 2.47K Increased by +0.22% | Aug 31, 25 |
| 16 | T. Rowe Price Health Sciences | 1.10M (1.15%) | -56.90K Decreased by -5.19% | Apr 30, 26 |
| 17 | PGIM Jennison Health Sciences Z | 1.05M (1.10%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Pictet-Biotech P USD | 990.78K (1.04%) | -58.88K Decreased by -5.94% | Feb 28, 26 |
| 19 | Bridge Builder Small/Mid Cap Growth | 988.75K (1.03%) | 23.11K Increased by +2.34% | May 31, 26 |
| 20 | Fidelity Small Cap Index | 958.44K (1.00%) | 1.39K Increased by +0.14% | Mar 31, 26 |