| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 14.29M (14.95%) | 106.28K Increased by +0.74% | Dec 31, 25 |
| 2 | Vanguard Group Inc | 9.14M (9.56%) | -34.63K Decreased by -0.38% | Dec 31, 25 |
| 3 | Wellington Management Company LLP | 8.04M (8.41%) | -344.10K Decreased by -4.28% | Dec 31, 25 |
| 4 | BlackRock Inc | 7.99M (8.36%) | 401.95K Increased by +5.03% | Dec 31, 25 |
| 5 | Farallon Capital Management, L.L.C. | 6.93M (7.25%) | 1.16M Increased by +16.77% | Dec 31, 25 |
| 6 | Driehaus Capital Management LLC | 6.39M (6.68%) | -93.87K Decreased by -1.47% | Dec 31, 25 |
| 7 | T. Rowe Price Associates, Inc. | 5.22M (5.47%) | -81.86K Decreased by -1.57% | Dec 31, 25 |
| 8 | HHG PLC | 4.44M (4.65%) | 581.90K Increased by +13.10% | Dec 31, 25 |
| 9 | EcoR1 Capital, LLC | 4.29M (4.49%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 10 | State Street Corporation | 3.26M (3.41%) | -308.48K Decreased by -9.48% | Mar 31, 24 |
| 11 | Baker Bros Advisors LP | 2.35M (2.46%) | 702.60K Increased by +29.88% | Mar 31, 26 |
| 12 | Point72 Asset Management, L.P. | 2.34M (2.44%) | 333.70K Increased by +14.28% | Dec 31, 25 |
| 13 | Geode Capital Management, LLC | 2.24M (2.35%) | -36.20K Decreased by -1.61% | Dec 31, 25 |
| 14 | Paradigm Biocapital Advisors LP | 2.21M (2.31%) | -340.00K Decreased by -15.38% | Dec 31, 25 |
| 15 | State Street Corp | 2.16M (2.26%) | -46.33K Decreased by -2.14% | Dec 31, 25 |
| 16 | Pictet Asset Manangement SA | 1.88M (1.97%) | 323.98K Increased by +17.19% | Mar 31, 26 |
| 17 | Morgan Stanley - Brokerage Accounts | 1.68M (1.75%) | 452.85K Increased by +27.00% | Jun 30, 24 |
| 18 | Novo A/S | 1.55M (1.62%) | -75.00K Decreased by -4.84% | Mar 31, 26 |
| 19 | Siren, L.L.C. | 1.51M (1.58%) | -180.97K Decreased by -12.00% | Dec 31, 25 |
| 20 | Vestal Point Capital LP | 1.50M (1.57%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 3.49M (3.66%) | 306.20K Increased by +8.76% | Mar 31, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.35M (3.51%) | 114.20K Increased by +3.41% | Mar 31, 26 |
| 3 | Fidelity OTC | 3.01M (3.15%) | 277.66K Increased by +9.22% | Mar 31, 26 |
| 4 | Vanguard Small Cap Index | 2.42M (2.53%) | 89.94K Increased by +3.72% | Mar 31, 26 |
| 5 | Vanguard US Total Market Shares ETF | 2.40M (2.51%) | 2.45K Increased by +0.10% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 2.30M (2.40%) | 19.36K Increased by +0.84% | Apr 30, 26 |
| 7 | T. Rowe Price New Horizons | 1.58M (1.65%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | US Small-Cap Growth II Equity Comp | 1.58M (1.65%) | 89.61K Increased by +5.67% | Mar 31, 26 |
| 9 | Vanguard Small Cap Growth Index Inv | 1.35M (1.41%) | 57.94K Increased by +4.29% | Mar 31, 26 |
| 10 | Fidelity Select Health Care | 1.28M (1.34%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 11 | Fidelity® Select Biotechnology | 1.23M (1.29%) | -136.40K Decreased by -11.06% | Nov 30, 23 |
| 12 | T. Rowe Price Health Sciences | 1.15M (1.21%) | -98.73K Decreased by -8.57% | Mar 31, 26 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 1.14M (1.20%) | 25.11K Increased by +2.20% | Mar 31, 26 |
| 14 | Vanguard Explorer Inv | 1.12M (1.17%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | SPDR® S&P Biotech ETF | 1.11M (1.16%) | 2.47K Increased by +0.22% | Aug 31, 25 |
| 16 | Pictet-Biotech P USD | 1.05M (1.10%) | 1.05M Increased by +100.00% | Jan 31, 26 |
| 17 | PGIM Jennison Health Sciences Z | 1.05M (1.10%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Bridge Builder Small/Mid Cap Growth | 965.64K (1.01%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 19 | Fidelity Small Cap Index | 957.05K (1.00%) | 10.41K Increased by +1.09% | Feb 28, 26 |
| 20 | Fidelity Small Cap Growth | 939.59K (0.98%) | 1.00K Increased by +0.11% | Feb 28, 26 |