| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 14.13M (16.10%) | 94.73K Increased by +0.67% | Jun 30, 25 |
| 2 | Vanguard Group Inc | 9.26M (10.55%) | -55.47K Decreased by -0.60% | Jun 30, 25 |
| 3 | BlackRock Inc | 7.42M (8.46%) | -237.85K Decreased by -3.21% | Jun 30, 25 |
| 4 | Driehaus Capital Management LLC | 6.40M (7.29%) | 160.12K Increased by +2.50% | Jun 30, 25 |
| 5 | Wellington Management Company LLP | 5.81M (6.62%) | -1.08M Decreased by -18.67% | Jun 30, 25 |
| 6 | T. Rowe Price Associates, Inc. | 5.59M (6.37%) | 478.14K Increased by +8.55% | Jun 30, 25 |
| 7 | Farallon Capital Management, L.L.C. | 4.65M (5.30%) | 41.00K Increased by +0.88% | Jun 30, 25 |
| 8 | EcoR1 Capital, LLC | 4.29M (4.89%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | HHG PLC | 3.41M (3.89%) | -14.12K Decreased by -0.41% | Jun 30, 25 |
| 10 | State Street Corporation | 3.26M (3.71%) | -308.48K Decreased by -9.48% | Mar 31, 24 |
| 11 | State Street Corp | 3.22M (3.68%) | -58.97K Decreased by -1.83% | Jun 30, 25 |
| 12 | Paradigm Biocapital Advisors LP | 2.34M (2.67%) | 397.38K Increased by +16.96% | Jun 30, 25 |
| 13 | Geode Capital Management, LLC | 2.21M (2.52%) | 22.39K Increased by +1.01% | Jun 30, 25 |
| 14 | Point72 Asset Management, L.P. | 2.00M (2.28%) | 1.22M Increased by +61.04% | Jun 30, 25 |
| 15 | Jennison Associates LLC | 1.99M (2.26%) | -132.65K Decreased by -6.68% | Jun 30, 25 |
| 16 | Siren, L.L.C. | 1.69M (1.92%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 17 | Morgan Stanley - Brokerage Accounts | 1.68M (1.91%) | 452.85K Increased by +27.00% | Jun 30, 24 |
| 18 | Novo A/S | 1.55M (1.77%) | 275.00K Increased by +17.74% | Jun 30, 25 |
| 19 | Vestal Point Capital LP | 1.50M (1.71%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | Perceptive Advisors LLC | 1.48M (1.68%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.95M (3.36%) | -62.07K Decreased by -2.11% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.40M (2.74%) | 2.45K Increased by +0.10% | Sep 30, 24 |
| 3 | Vanguard Small Cap Index | 2.27M (2.59%) | -15.07K Decreased by -0.66% | Jul 31, 25 |
| 4 | Fidelity OTC | 2.22M (2.53%) | 49.02K Increased by +2.20% | Jul 31, 25 |
| 5 | iShares Russell 2000 ETF | 2.17M (2.47%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | US Small-Cap Growth II Equity Comp | 2.06M (2.34%) | -58.41K Decreased by -2.84% | Jun 30, 25 |
| 7 | T. Rowe Price New Horizons | 1.95M (2.22%) | -104.71K Decreased by -5.37% | Jul 31, 25 |
| 8 | Vanguard Health Care Inv | 1.32M (1.51%) | -961.79K Decreased by -72.72% | Jun 30, 25 |
| 9 | Fidelity Select Health Care | 1.29M (1.47%) | 9.10K Increased by +0.71% | Jul 31, 25 |
| 10 | Vanguard Small Cap Growth Index Inv | 1.28M (1.46%) | -1.25K Decreased by -0.10% | Jul 31, 25 |
| 11 | T. Rowe Price Integrated US SmCapGrEq | 1.28M (1.46%) | 722.20K Increased by +56.36% | Dec 31, 24 |
| 12 | Fidelity® Select Biotechnology | 1.23M (1.41%) | -136.40K Decreased by -11.06% | Nov 30, 23 |
| 13 | T. Rowe Price Health Sciences | 1.12M (1.27%) | 63.04K Increased by +5.65% | Jul 31, 25 |
| 14 | SPDR® S&P Biotech ETF | 1.11M (1.26%) | 2.47K Increased by +0.22% | Aug 31, 25 |
| 15 | PGIM Jennison Health Sciences Z | 1.05M (1.20%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 1.01M (1.15%) | -440.74K Decreased by -43.85% | Jul 31, 25 |
| 17 | Vanguard Explorer Inv | 981.22K (1.12%) | -102.61K Decreased by -10.46% | Jun 30, 25 |
| 18 | Bridge Builder Small/Mid Cap Growth | 927.28K (1.06%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 19 | MEDICAL BioHealth EUR Acc | 921.76K (1.05%) | 109.00K Increased by +11.83% | Jan 31, 25 |
| 20 | Fidelity Select Biotechnology | 919.40K (1.05%) | 0.00 Increased by 0.00% | Jul 31, 25 |