| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 14.03M (15.12%) | 5.10M Increased by +36.37% | Mar 31, 25 |
| 2 | Vanguard Group Inc | 9.26M (9.98%) | -55.47K Decreased by -0.60% | Jun 30, 25 |
| 3 | BlackRock Inc | 7.66M (8.25%) | 141.38K Increased by +1.85% | Mar 31, 25 |
| 4 | Driehaus Capital Management LLC | 6.24M (6.73%) | 98.89K Increased by +1.58% | Mar 31, 25 |
| 5 | Wellington Management Company LLP | 5.81M (6.26%) | -1.08M Decreased by -18.67% | Jun 30, 25 |
| 6 | T. Rowe Price Associates, Inc. | 5.59M (6.03%) | 478.14K Increased by +8.55% | Jun 30, 25 |
| 7 | Farallon Capital Management, L.L.C. | 4.61M (4.96%) | 530.00K Increased by +11.51% | Mar 31, 25 |
| 8 | EcoR1 Capital, LLC | 4.29M (4.62%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | HHG PLC | 3.41M (3.68%) | -14.12K Decreased by -0.41% | Jun 30, 25 |
| 10 | State Street Corp | 3.28M (3.54%) | 292.44K Increased by +8.91% | Mar 31, 25 |
| 11 | State Street Corporation | 3.26M (3.51%) | -308.48K Decreased by -9.48% | Mar 31, 24 |
| 12 | Point72 Asset Management, L.P. | 2.79M (3.01%) | 488.30K Increased by +17.51% | Dec 31, 24 |
| 13 | Geode Capital Management, LLC | 2.19M (2.36%) | 92.09K Increased by +4.20% | Mar 31, 25 |
| 14 | Jennison Associates LLC | 1.99M (2.14%) | -132.65K Decreased by -6.68% | Jun 30, 25 |
| 15 | Paradigm Biocapital Advisors LP | 1.95M (2.10%) | 35.41K Increased by +1.82% | Mar 31, 25 |
| 16 | Siren, L.L.C. | 1.69M (1.82%) | 78.96K Increased by +4.68% | Mar 31, 25 |
| 17 | Morgan Stanley - Brokerage Accounts | 1.68M (1.81%) | 452.85K Increased by +27.00% | Jun 30, 24 |
| 18 | Vestal Point Capital LP | 1.50M (1.62%) | 1.50M Increased by +100.00% | Mar 31, 25 |
| 19 | Perceptive Advisors LLC | 1.48M (1.59%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Bain Capital Life Sciences Investors, LLC | 1.28M (1.37%) | -1.03M Decreased by -80.75% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.95M (3.17%) | -62.07K Decreased by -2.11% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.40M (2.59%) | 2.45K Increased by +0.10% | Sep 30, 24 |
| 3 | Vanguard Small Cap Index | 2.27M (2.45%) | -15.07K Decreased by -0.66% | Jul 31, 25 |
| 4 | Fidelity OTC | 2.18M (2.34%) | 491.00 Increased by +0.02% | Jun 30, 25 |
| 5 | iShares Russell 2000 ETF | 2.12M (2.29%) | -40.32K Decreased by -1.90% | Jul 31, 25 |
| 6 | T. Rowe Price New Horizons | 2.06M (2.22%) | 136.71K Increased by +6.65% | Jun 30, 25 |
| 7 | US Small-Cap Growth II Equity Comp | 2.06M (2.22%) | -58.41K Decreased by -2.84% | Jun 30, 25 |
| 8 | Vanguard Health Care Inv | 1.32M (1.43%) | -961.79K Decreased by -72.72% | Jun 30, 25 |
| 9 | Vanguard Small Cap Growth Index Inv | 1.28M (1.38%) | -1.25K Decreased by -0.10% | Jul 31, 25 |
| 10 | T. Rowe Price Integrated US SmCapGrEq | 1.28M (1.38%) | 722.20K Increased by +56.36% | Dec 31, 24 |
| 11 | Fidelity Select Health Care | 1.28M (1.38%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Fidelity® Select Biotechnology | 1.23M (1.33%) | -136.40K Decreased by -11.06% | Nov 30, 23 |
| 13 | SPDR® S&P Biotech ETF | 1.11M (1.19%) | 33.10K Increased by +2.99% | Jul 31, 25 |
| 14 | T. Rowe Price Health Sciences | 1.05M (1.14%) | 137.56K Increased by +13.06% | Jun 30, 25 |
| 15 | PGIM Jennison Health Sciences Z | 1.05M (1.13%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 1.01M (1.08%) | -440.74K Decreased by -43.85% | Jul 31, 25 |
| 17 | Vanguard Explorer Inv | 981.22K (1.06%) | -102.61K Decreased by -10.46% | Jun 30, 25 |
| 18 | Fidelity Small Cap Index | 929.12K (1.00%) | 584.00 Increased by +0.06% | May 31, 25 |
| 19 | Bridge Builder Small/Mid Cap Growth | 927.28K (1.00%) | -87.16K Decreased by -9.40% | Jul 31, 25 |
| 20 | MEDICAL BioHealth EUR Acc | 921.76K (0.99%) | 109.00K Increased by +11.83% | Jan 31, 25 |