| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | venBio Select Advisor LLC | 11.11M (11.50%) | 811.11K Increased by +7.30% | Dec 31, 23 |
| 2 | BlackRock Inc | 9.61M (9.94%) | 1.82M Increased by +18.92% | Dec 31, 23 |
| 3 | RA Capital Management, LLC | 6.94M (7.18%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 4 | Vanguard Group Inc | 6.31M (6.53%) | 558.56K Increased by +8.86% | Dec 31, 23 |
| 5 | HHG PLC | 6.10M (6.32%) | -699.69K Decreased by -11.46% | Dec 31, 23 |
| 6 | T. Rowe Price Associates, Inc. | 4.47M (4.62%) | 2.56M Increased by +57.37% | Dec 31, 23 |
| 7 | Perceptive Advisors LLC | 4.02M (4.16%) | -18.79K Decreased by -0.47% | Dec 31, 23 |
| 8 | Jennison Associates LLC | 3.99M (4.13%) | 437.44K Increased by +10.96% | Dec 31, 23 |
| 9 | Franklin Resources Inc | 3.27M (3.38%) | -39.99K Decreased by -1.22% | Dec 31, 23 |
| 10 | Holocene Advisors, LP | 3.12M (3.23%) | 3.12M Increased by +100.00% | Sep 30, 23 |
| 11 | Octagon Capital Advisors LP | 3.07M (3.18%) | -1.50M Decreased by -48.71% | Sep 30, 23 |
| 12 | FMR Inc | 3.06M (3.17%) | 1.49M Increased by +48.76% | Dec 31, 23 |
| 13 | State Street Corporation | 2.80M (2.90%) | 511.97K Increased by +18.30% | Dec 31, 23 |
| 14 | Adage Capital Partners Gp LLC | 2.63M (2.72%) | -1.50M Decreased by -56.96% | Dec 31, 23 |
| 15 | Point72 Asset Management, L.P. | 2.43M (2.51%) | 2.43M Increased by +100.00% | Sep 30, 23 |
| 16 | Geode Capital Management, LLC | 2.38M (2.46%) | 304.55K Increased by +12.80% | Dec 31, 23 |
| 17 | Fred Alger Management, LLC | 1.97M (2.04%) | -204.45K Decreased by -10.39% | Dec 31, 23 |
| 18 | Wagonhound Investments, LP | 1.84M (1.90%) | 1.14M Increased by +62.12% | Sep 30, 23 |
| 19 | Cormorant Asset Management, LLC | 1.80M (1.86%) | -2.05M Decreased by -113.89% | Dec 31, 23 |
| 20 | Foresite Capital Management IV, LLC | 1.79M (1.85%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.53M (3.66%) | 57.09K Increased by +1.62% | Jan 31, 24 |
| 2 | iShares Russell 2000 ETF | 2.78M (2.88%) | -50.62K Decreased by -1.82% | Jan 31, 24 |
| 3 | T. Rowe Price New Horizons | 2.02M (2.09%) | 1.29M Increased by +64.15% | Dec 31, 23 |
| 4 | US Small-Cap Growth II Equity Comp | 2.02M (2.09%) | 2.02M Increased by +100.00% | Dec 31, 23 |
| 5 | Franklin Biotechnology Discv A(acc)USD | 1.70M (1.76%) | 23.95K Increased by +1.41% | Dec 31, 23 |
| 6 | Janus Henderson Global Life Sciences | 1.61M (1.67%) | -60.78K Decreased by -3.77% | Dec 31, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 1.61M (1.67%) | -16.21K Decreased by -1.01% | Jan 31, 24 |
| 8 | Alger Small Cap Focus Composite | 1.58M (1.64%) | -28.19K Decreased by -1.78% | Nov 30, 23 |
| 9 | Alger Small Cap Focus I | 1.58M (1.64%) | -28.19K Decreased by -1.78% | Nov 30, 23 |
| 10 | Janus Henderson Global Life Sciences D | 1.47M (1.52%) | -140.65K Decreased by -9.55% | Feb 29, 24 |
| 11 | Jennison Health Sciences Equity | 1.22M (1.26%) | -270.45K Decreased by -22.15% | Dec 31, 23 |
| 12 | PGIM Jennison Health Sciences Z | 1.22M (1.26%) | -426.75K Decreased by -34.96% | Dec 31, 23 |
| 13 | Janus Henderson Glb Life Scn I2 USD | 1.22M (1.26%) | -27.18K Decreased by -2.23% | Dec 31, 23 |
| 14 | Janus Selection Global Life Science AUSD | 1.22M (1.26%) | -71.35K Decreased by -5.86% | Dec 31, 23 |
| 15 | MEDICAL BioHealth EUR Acc | 1.17M (1.21%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 16 | Fidelity Small Cap Index | 1.16M (1.20%) | 10.49K Increased by +0.91% | Feb 29, 24 |
| 17 | Fidelity Canadian Large Cp Mlt Ast Bs O | 1.00M (1.03%) | 1.00M Increased by +100.00% | Feb 29, 24 |
| 18 | iShares Russell 2000 Growth ETF | 983.90K (1.02%) | 1.15K Increased by +0.12% | Jan 31, 24 |
| 19 | Janus Henderson US SMID Cap Growth | 970.74K (1.00%) | -223.22K Decreased by -22.99% | Dec 31, 23 |
| 20 | Janus Henderson Triton D | 967.35K (1.00%) | -3.39K Decreased by -0.35% | Feb 29, 24 |