| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 9.53M (1.27%) | -1.04M Decreased by -10.88% | Dec 31, 24 |
| 2 | Capital Research & Mgmt Co - Division 3 | 6.11M (0.82%) | -317.72K Decreased by -5.20% | Dec 31, 24 |
| 3 | PRIMECAP Management Company | 5.10M (0.68%) | 124.61K Increased by +2.44% | Dec 31, 24 |
| 4 | Hillhouse Capital Advisors, Ltd. | 3.80M (0.51%) | -1.37M Decreased by -36.08% | Dec 31, 24 |
| 5 | Baillie Gifford & Co Limited. | 3.67M (0.49%) | -34.56K Decreased by -0.94% | Dec 31, 24 |
| 6 | T. Rowe Price Associates, Inc. | 2.94M (0.39%) | 237.08K Increased by +8.07% | Dec 31, 24 |
| 7 | FMR Inc | 1.85M (0.25%) | 188.05K Increased by +10.18% | Dec 31, 24 |
| 8 | Temasek Holdings Ltd. | 1.53M (0.20%) | -863.25K Decreased by -56.59% | Dec 31, 24 |
| 9 | Morgan Stanley - Brokerage Accounts | 738.14K (0.10%) | 565.11K Increased by +76.56% | Dec 31, 24 |
| 10 | BlackRock Inc | 733.98K (0.10%) | -158.37K Decreased by -21.58% | Dec 31, 24 |
| 11 | Point72 Asset Management, L.P. | 667.17K (0.09%) | 285.78K Increased by +42.84% | Sep 30, 24 |
| 12 | Siren, L.L.C. | 653.72K (0.09%) | 90.41K Increased by +13.83% | Dec 31, 24 |
| 13 | Paradigm Biocapital Advisors LP | 616.02K (0.08%) | 415.69K Increased by +67.48% | Dec 31, 24 |
| 14 | Capital International Inc /ca/ | 554.93K (0.07%) | -69.97K Decreased by -12.61% | Dec 31, 24 |
| 15 | Boxer Capital LLC | 500.00K (0.07%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | Goldman Sachs Group Inc | 428.68K (0.06%) | 350.80K Increased by +81.83% | Dec 31, 23 |
| 17 | PUBLIC INVESTMENT FUND | 354.38K (0.05%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Vestal Point Capital LP | 350.00K (0.05%) | 25.00K Increased by +7.14% | Jun 30, 24 |
| 19 | Great West Life Assurance Co | 324.72K (0.04%) | 273.09K Increased by +84.10% | Sep 30, 23 |
| 20 | Artal Group S A | 303.37K (0.04%) | -101.41K Decreased by -33.43% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds New Perspective A | 2.80M (0.37%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Capital Group New Perspective Comp | 2.80M (0.37%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Vanguard PRIMECAP Inv | 2.31M (0.31%) | 105.00K Increased by +4.55% | Dec 31, 24 |
| 4 | AF High Growth (AFRIS) | 1.81M (0.24%) | 1.81M Increased by +100.00% | Feb 29, 24 |
| 5 | American Funds New World A | 1.16M (0.15%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | Capital Group New Geography Equity Comp | 1.16M (0.15%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | Invesco Emerging Markets Equity | 1.15M (0.15%) | -8.69K Decreased by -0.76% | Sep 30, 23 |
| 8 | Vanguard Capital Opportunity Inv | 1.12M (0.15%) | 37.50K Increased by +3.35% | Dec 31, 24 |
| 9 | Global Balanced (AFRIS) | 829.42K (0.11%) | 829.42K Increased by +100.00% | Feb 29, 24 |
| 10 | T. Rowe Price Health Sciences | 725.72K (0.10%) | -17.51K Decreased by -2.41% | Dec 31, 24 |
| 11 | PRIMECAP Odyssey Aggressive Growth | 698.89K (0.09%) | -6.07K Decreased by -0.87% | Dec 31, 24 |
| 12 | T. Rowe Price International Gr Eq Tr-D | 673.60K (0.09%) | 86.03K Increased by +12.77% | Dec 31, 24 |
| 13 | PRIMECAP Odyssey Growth | 671.43K (0.09%) | -12.30K Decreased by -1.83% | Dec 31, 24 |
| 14 | Fidelity Growth Compy Commingled Pl S | 664.76K (0.09%) | 6.55K Increased by +0.98% | Dec 31, 24 |
| 15 | T. Rowe Price International Growth Eq | 651.99K (0.09%) | 33.92K Increased by +5.20% | Dec 31, 24 |
| 16 | T. Rowe Price International Stock | 651.99K (0.09%) | 37.60K Increased by +5.77% | Dec 31, 24 |
| 17 | Fidelity Growth Compy Commingled Pl O | 648.53K (0.09%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 18 | American Funds Europacific Growth A | 637.89K (0.09%) | 37.46K Increased by +5.87% | Dec 31, 24 |
| 19 | Capital Group EuroPacific Growth Comp | 637.89K (0.09%) | 37.46K Increased by +5.87% | Dec 31, 24 |
| 20 | Invesco Developing Markets A | 620.20K (0.08%) | -529.79K Decreased by -85.42% | Nov 30, 23 |