| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 10.51M (26.73%) | 112.89K Increased by +1.07% | Jun 30, 25 |
| 2 | Vestal Point Capital LP | 5.60M (14.24%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | NEA Management Company, LLC | 4.45M (11.31%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | RA Capital Management, LLC | 3.53M (8.97%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 5 | Bellevue Group AG | 2.73M (6.95%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 2.10M (5.35%) | -253.80K Decreased by -12.07% | Jun 30, 25 |
| 7 | TANG CAPITAL MANAGEMENT LLC | 2.07M (5.26%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | BlackRock Inc | 1.09M (2.77%) | -2.38M Decreased by -218.35% | Jun 30, 25 |
| 9 | Artal Group S A | 1.05M (2.66%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 10 | Siren, L.L.C. | 1.05M (2.66%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Millennium Management LLC | 944.85K (2.40%) | -159.06K Decreased by -16.83% | Jun 30, 25 |
| 12 | Deerfield Management Co | 930.45K (2.37%) | -869.55K Decreased by -93.46% | Sep 30, 23 |
| 13 | Renaissance Technologies Corp | 904.00K (2.30%) | 650.20K Increased by +71.92% | Dec 31, 24 |
| 14 | LAURION CAPITAL MANAGEMENT LP | 878.29K (2.23%) | 878.29K Increased by +100.00% | Mar 31, 24 |
| 15 | ExodusPoint Capital Management, LP | 872.68K (2.22%) | 284.05K Increased by +32.55% | Sep 30, 24 |
| 16 | State Street Corp | 867.19K (2.21%) | -16.25K Decreased by -1.87% | Mar 31, 25 |
| 17 | Ally Bridge Group (NY) LLC | 835.00K (2.12%) | 835.00K Increased by +100.00% | Jun 30, 24 |
| 18 | JPMorgan Chase & Co | 821.63K (2.09%) | -285.95K Decreased by -34.80% | Dec 31, 23 |
| 19 | Marshall Wace Asset Management Ltd | 737.88K (1.88%) | 737.88K Increased by +100.00% | Jun 30, 25 |
| 20 | CHI Advisors LLC | 720.00K (1.83%) | -30.00K Decreased by -4.17% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 8.52M (21.66%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | T. Rowe Price Small-Cap Stock | 2.53M (6.44%) | 32.28K Increased by +1.27% | Jul 31, 25 |
| 3 | T. Rowe Price US Small-Cap Core Equity | 2.50M (6.36%) | 130.07K Increased by +5.20% | Jun 30, 25 |
| 4 | T. Rowe Price Small-Cap Value | 2.50M (6.35%) | 80.16K Increased by +3.21% | Jul 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 1.33M (3.38%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 1.30M (3.31%) | -28.70K Decreased by -2.21% | Jul 31, 25 |
| 7 | T. Rowe Price Instl Small-Cap Stock | 1.30M (3.30%) | 12.42K Increased by +0.96% | Jul 31, 25 |
| 8 | T. Rowe Price U.S. SC Core Eq Tr-D | 1.26M (3.21%) | 46.68K Increased by +3.70% | Jun 30, 25 |
| 9 | T. Rowe Price U.S. SC Value Eq Tr-D | 1.25M (3.18%) | 6.86K Increased by +0.55% | Jun 30, 25 |
| 10 | T. Rowe Price U.S. SC Value Eq Tr-Z | 1.24M (3.16%) | 2.28K Increased by +0.18% | Mar 31, 25 |
| 11 | T. Rowe Price U.S. SC Core Eq Tr-Z | 1.22M (3.09%) | 2.29K Increased by +0.19% | Mar 31, 25 |
| 12 | iShares Russell 2000 ETF | 992.11K (2.52%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | Invesco Dorsey Wright SmallCap Momt ETF | 685.85K (1.74%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | T. Rowe Price US Smlr Cm Eq A USD | 670.35K (1.70%) | -34.40K Decreased by -5.13% | Apr 30, 25 |
| 15 | Belfius Equities Cure C Cap | 540.00K (1.37%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 16 | Candriam Global Equities Oncology | 540.00K (1.37%) | 40.00K Increased by +7.41% | Dec 31, 23 |
| 17 | T. Rowe Price US Smlr Coms Eq A | 537.62K (1.37%) | -6.90K Decreased by -1.28% | Jul 31, 25 |
| 18 | BlackRock Health Sciences Term Trust | 504.98K (1.28%) | -361.03K Decreased by -71.49% | Jun 30, 25 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 465.28K (1.18%) | -155.08K Decreased by -33.33% | Jul 31, 25 |
| 20 | Fidelity Small Cap Index | 408.17K (1.04%) | -18.90K Decreased by -4.63% | May 31, 25 |