| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 10.74M (23.38%) | 231.97K Increased by +2.16% | Sep 30, 25 |
| 2 | NEA Management Company, LLC | 4.45M (9.68%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | RA Capital Management, LLC | 3.53M (7.67%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 4 | Bellevue Group AG | 2.73M (5.95%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Vanguard Group Inc | 2.19M (4.76%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | TANG CAPITAL MANAGEMENT LLC | 2.07M (4.51%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 7 | Marshall Wace Asset Management Ltd | 1.30M (2.83%) | 561.33K Increased by +43.21% | Sep 30, 25 |
| 8 | Artal Group S A | 1.05M (2.28%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 9 | Siren, L.L.C. | 1.05M (2.28%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Arrowstreet Capital Limited Partnership | 1.04M (2.26%) | 143.62K Increased by +13.80% | Dec 31, 25 |
| 11 | BlackRock Inc | 1.03M (2.24%) | -62.77K Decreased by -6.11% | Sep 30, 25 |
| 12 | Renaissance Technologies Corp | 949.74K (2.07%) | 350.33K Increased by +36.89% | Dec 31, 25 |
| 13 | Deerfield Management Co | 930.45K (2.03%) | -869.55K Decreased by -93.46% | Sep 30, 23 |
| 14 | LAURION CAPITAL MANAGEMENT LP | 878.29K (1.91%) | 878.29K Increased by +100.00% | Mar 31, 24 |
| 15 | ExodusPoint Capital Management, LP | 872.68K (1.90%) | 284.05K Increased by +32.55% | Sep 30, 24 |
| 16 | Vestal Point Capital LP | 870.00K (1.89%) | -4.68M Decreased by -537.93% | Dec 31, 25 |
| 17 | State Street Corp | 867.19K (1.89%) | -16.25K Decreased by -1.87% | Mar 31, 25 |
| 18 | Dimensional Fund Advisors, Inc. | 857.01K (1.87%) | 401.14K Increased by +46.81% | Dec 31, 25 |
| 19 | Millennium Management LLC | 850.33K (1.85%) | -94.52K Decreased by -11.12% | Sep 30, 25 |
| 20 | Ally Bridge Group (NY) LLC | 835.00K (1.82%) | 835.00K Increased by +100.00% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 8.52M (18.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | T. Rowe Price Small-Cap Stock | 2.65M (5.77%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | T. Rowe Price US Small-Cap Core Equity | 2.65M (5.77%) | 98.68K Increased by +3.72% | Dec 31, 25 |
| 4 | T. Rowe Price Small-Cap Value | 2.13M (4.64%) | -91.58K Decreased by -4.29% | Dec 31, 25 |
| 5 | T. Rowe Price Instl Small-Cap Stock | 1.40M (3.04%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | T. Rowe Price U.S. SC Value Eq Tr-D | 1.36M (2.96%) | 2.09K Increased by +0.15% | Dec 31, 25 |
| 7 | Vanguard US Total Market Shares ETF | 1.33M (2.89%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 8 | Vanguard Total Stock Mkt Idx Inv | 1.30M (2.82%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 9 | T. Rowe Price U.S. SC Core Eq Tr-D | 1.28M (2.79%) | 2.63K Increased by +0.21% | Dec 31, 25 |
| 10 | T. Rowe Price U.S. SC Value Eq Tr-Z | 1.24M (2.70%) | 2.28K Increased by +0.18% | Mar 31, 25 |
| 11 | T. Rowe Price U.S. SC Core Eq Tr-Z | 1.22M (2.65%) | 2.29K Increased by +0.19% | Mar 31, 25 |
| 12 | iShares Russell 2000 ETF | 992.11K (2.16%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | Invesco Dorsey Wright SmallCap Momt ETF | 685.85K (1.49%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | T. Rowe Price US Smlr Cm Eq A USD | 670.35K (1.46%) | -34.40K Decreased by -5.13% | Apr 30, 25 |
| 15 | Belfius Equities Cure C Cap | 540.00K (1.18%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 16 | Candriam Global Equities Oncology | 540.00K (1.18%) | 40.00K Increased by +7.41% | Dec 31, 23 |
| 17 | T. Rowe Price US Smlr Coms Eq A | 529.23K (1.15%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 18 | BlackRock Health Sciences Term Trust | 504.98K (1.10%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 465.28K (1.01%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 20 | Fidelity Enhanced Small Cap ETF | 447.45K (0.97%) | 2.17K Increased by +0.48% | Feb 26, 26 |