| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.28M (17.11%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Westfield Capital Management Company, L.P. | 5.45M (9.07%) | -27.86K Decreased by -0.51% | Jun 30, 25 |
| 3 | Westfield Capital Management Company, LP | 5.13M (8.54%) | 170.94K Increased by +3.33% | Sep 30, 24 |
| 4 | venBio Select Advisor LLC | 4.98M (8.29%) | -238.00K Decreased by -4.78% | Jun 30, 25 |
| 5 | FMR Inc | 4.53M (7.54%) | -141.22K Decreased by -3.12% | Jun 30, 25 |
| 6 | HHG PLC | 4.43M (7.37%) | -59.16K Decreased by -1.34% | Jun 30, 25 |
| 7 | Artisan Partners Limited Partnership | 3.99M (6.64%) | -266.20K Decreased by -6.67% | Jun 30, 25 |
| 8 | T. Rowe Price Investment Management,Inc. | 3.58M (5.96%) | 529.72K Increased by +14.78% | Jun 30, 25 |
| 9 | Capital Research & Mgmt Co - Division 3 | 3.05M (5.07%) | 172.14K Increased by +5.65% | Jun 30, 25 |
| 10 | Morgan Stanley - Brokerage Accounts | 1.90M (3.17%) | 1.08M Increased by +56.62% | Mar 31, 25 |
| 11 | Massachusetts Financial Services Company | 1.90M (3.17%) | 23.93K Increased by +1.26% | Jun 30, 25 |
| 12 | T. Rowe Price Associates, Inc. | 1.88M (3.12%) | -380.61K Decreased by -20.29% | Jun 30, 25 |
| 13 | Franklin Resources Inc | 1.75M (2.92%) | 113.35K Increased by +6.46% | Jun 30, 25 |
| 14 | Perceptive Advisors LLC | 963.89K (1.60%) | 963.89K Increased by +100.00% | Jun 30, 25 |
| 15 | Amvescap Plc. | 947.23K (1.58%) | -251.25K Decreased by -26.53% | Jun 30, 25 |
| 16 | Wellington Management Company LLP | 918.10K (1.53%) | 330.33K Increased by +35.98% | Jun 30, 25 |
| 17 | Polar Capital Holdings PLC | 837.78K (1.39%) | 312.78K Increased by +37.33% | Jun 30, 25 |
| 18 | Adage Capital Partners Gp LLC | 820.51K (1.37%) | 611.00K Increased by +74.47% | Jun 30, 24 |
| 19 | Camber Capital Management LLC | 800.00K (1.33%) | 100.00K Increased by +12.50% | Dec 31, 24 |
| 20 | Sofinnova Ventures | 734.28K (1.22%) | -19.75K Decreased by -2.69% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | TimesSquare CIT Mid Cap Growth A | 9.14M (15.21%) | 9.09M Increased by +99.45% | Dec 31, 23 |
| 2 | MFS Mid Cap Growth Equity | 1.30M (2.17%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | MFS Mid Cap Growth A | 1.27M (2.11%) | -34.08K Decreased by -2.68% | Jul 31, 25 |
| 4 | American Funds Growth Fund of Amer A | 1.06M (1.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Capital Group Growth Fnd of Amer Comp | 1.06M (1.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | T. Rowe Price US Mid-Cap Growth Equity | 1.02M (1.70%) | -1.20K Decreased by -0.12% | Jun 30, 25 |
| 7 | T. Rowe Price Mid-Cap Growth | 1.02M (1.69%) | -1.90K Decreased by -0.19% | Jul 31, 25 |
| 8 | Janus Henderson Enterprise D | 976.88K (1.63%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Janus Inst Mid Cap Growth CF | 976.88K (1.63%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Artisan Mid Cap Investor | 875.65K (1.46%) | -63.21K Decreased by -7.22% | Jun 30, 25 |
| 11 | Artisan U.S. Mid-Cap Growth | 875.65K (1.46%) | -63.21K Decreased by -7.22% | Jun 30, 25 |
| 12 | T. Rowe Price Health Sciences | 828.36K (1.38%) | 135.01K Increased by +16.30% | Jul 31, 25 |
| 13 | Fidelity Select Health Care | 740.00K (1.23%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 14 | Fidelity® Select Biotechnology | 659.41K (1.10%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | CTIVP Westfield Slct LgCap Gro 1 | 631.98K (1.05%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | American Funds New Perspective A | 623.16K (1.04%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 17 | Capital Group New Perspective Comp | 623.16K (1.04%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Bridge Builder Small/Mid Cap Growth | 621.87K (1.03%) | 13.03K Increased by +2.10% | Aug 31, 25 |
| 19 | Fidelity Select Biotechnology | 582.50K (0.97%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 20 | American Funds SMALLCAP World A | 579.16K (0.96%) | 0.00 Increased by 0.00% | Jun 30, 25 |