| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.28M (16.55%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Westfield Capital Management Company, LP | 5.13M (8.27%) | 170.94K Increased by +3.33% | Sep 30, 24 |
| 3 | venBio Select Advisor LLC | 5.06M (8.15%) | -48.61K Decreased by -0.96% | Mar 31, 26 |
| 4 | Westfield Capital Management Company, L.P. | 4.81M (7.75%) | -372.26K Decreased by -7.73% | Mar 31, 26 |
| 5 | Lombard Odier Asset Management (Europe) Ltd | 4.27M (6.87%) | 4.27M Increased by +100.00% | Sep 30, 25 |
| 6 | FMR Inc | 4.15M (6.69%) | -318.42K Decreased by -7.67% | Dec 31, 25 |
| 7 | HHG PLC | 4.06M (6.54%) | -261.42K Decreased by -6.44% | Dec 31, 25 |
| 8 | Artisan Partners Limited Partnership | 3.23M (5.20%) | 4.30K Increased by +0.13% | Mar 31, 26 |
| 9 | T. Rowe Price Investment Management,Inc. | 2.75M (4.42%) | 81.23K Increased by +2.96% | Dec 31, 25 |
| 10 | Franklin Resources Inc | 2.05M (3.30%) | 141.87K Increased by +6.91% | Mar 31, 26 |
| 11 | Capital Research & Mgmt Co - Division 3 | 1.96M (3.15%) | -1.11M Decreased by -56.42% | Mar 31, 26 |
| 12 | Massachusetts Financial Services Company | 1.86M (3.00%) | -25.72K Decreased by -1.38% | Mar 31, 26 |
| 13 | Wellington Management Company LLP | 1.76M (2.84%) | -36.21K Decreased by -2.05% | Dec 31, 25 |
| 14 | T. Rowe Price Associates, Inc. | 1.57M (2.53%) | -155.97K Decreased by -9.93% | Dec 31, 25 |
| 15 | American Century Companies Inc | 1.44M (2.32%) | 898.53K Increased by +62.26% | Dec 31, 25 |
| 16 | Perceptive Advisors LLC | 1.09M (1.75%) | 124.61K Increased by +11.45% | Sep 30, 25 |
| 17 | Capital World Investors | 900.52K (1.45%) | 900.52K Increased by +100.00% | Mar 31, 26 |
| 18 | Principal Financial Group Inc | 896.40K (1.44%) | -130.01K Decreased by -14.50% | Mar 31, 26 |
| 19 | Polar Capital Holdings PLC | 857.91K (1.38%) | 20.13K Increased by +2.35% | Sep 30, 25 |
| 20 | Adage Capital Partners Gp LLC | 820.51K (1.32%) | 611.00K Increased by +74.47% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | TimesSquare CIT Mid Cap Growth A | 9.14M (14.71%) | 9.09M Increased by +99.45% | Dec 31, 23 |
| 2 | T. Rowe Price Capital Appreciation | 2.74M (4.41%) | 453.50K Increased by +16.55% | Mar 31, 26 |
| 3 | MFS Mid Cap Growth A | 1.27M (2.05%) | -5.90K Decreased by -0.46% | Mar 31, 26 |
| 4 | MFS Mid Cap Growth Equity | 1.27M (2.05%) | -5.90K Decreased by -0.46% | Mar 31, 26 |
| 5 | American Funds Growth Fund of Amer A | 1.21M (1.95%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 6 | Capital Group Growth Fnd of Amer Comp | 1.21M (1.95%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Vanguard Health Care Inv | 1.10M (1.78%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | Franklin DynaTech A | 1.10M (1.77%) | 100.00K Increased by +9.09% | Mar 31, 26 |
| 9 | Franklin Innovation Composite | 1.10M (1.77%) | 100.00K Increased by +9.09% | Mar 31, 26 |
| 10 | Franklin DynaTech Fund A | 1.00M (1.61%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 11 | Janus Henderson Mid Cap Growth MA | 976.88K (1.57%) | 976.88K Increased by +100.00% | Sep 30, 25 |
| 12 | T. Rowe Price Mid-Cap Growth | 783.40K (1.26%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 13 | T. Rowe Price US Mid-Cap Growth Equity | 783.40K (1.26%) | -700.00 Decreased by -0.09% | Mar 31, 26 |
| 14 | Janus Inst Mid Cap Growth CF | 731.87K (1.18%) | -245.01K Decreased by -33.48% | Dec 31, 25 |
| 15 | Fidelity Select Health Care | 700.00K (1.13%) | -16.00K Decreased by -2.29% | Mar 31, 26 |
| 16 | T. Rowe Price Health Sciences | 699.37K (1.13%) | 16.20K Increased by +2.32% | Mar 31, 26 |
| 17 | Artisan Mid Cap Investor | 678.34K (1.09%) | -26.83K Decreased by -3.95% | Mar 31, 26 |
| 18 | Artisan U.S. Mid-Cap Growth | 678.34K (1.09%) | -26.83K Decreased by -3.95% | Mar 31, 26 |
| 19 | American Century US Premier Lg Cp Gr | 664.00K (1.07%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | American Century Ultra® Inv | 664.00K (1.07%) | 0.00 Increased by 0.00% | Mar 31, 26 |