| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 20.22M (16.57%) | 799.94K Increased by +3.96% | Sep 30, 25 |
| 2 | Vanguard Group Inc | 15.29M (12.53%) | -742.75K Decreased by -4.86% | Dec 31, 25 |
| 3 | venBio Select Advisor LLC | 10.63M (8.71%) | -275.00K Decreased by -2.59% | Dec 31, 25 |
| 4 | State Street Corporation | 6.56M (5.38%) | -264.41K Decreased by -4.03% | Mar 31, 24 |
| 5 | FMR Inc | 6.52M (5.34%) | 760.58K Increased by +11.66% | Dec 31, 25 |
| 6 | State Street Corp | 6.40M (5.24%) | 26.31K Increased by +0.41% | Sep 30, 25 |
| 7 | Artal Group S A | 3.19M (2.61%) | 152.72K Increased by +4.79% | Jun 30, 24 |
| 8 | Geode Capital Management, LLC | 3.13M (2.57%) | 152.54K Increased by +4.87% | Sep 30, 25 |
| 9 | Slate Path Capital LP | 2.52M (2.07%) | -2.46M Decreased by -97.42% | Dec 31, 25 |
| 10 | Amvescap Plc. | 2.31M (1.89%) | -136.73K Decreased by -5.93% | Dec 31, 23 |
| 11 | Baker Bros Advisors LP | 2.18M (1.78%) | 504.88K Increased by +23.21% | Dec 31, 25 |
| 12 | Goldman Sachs Group Inc | 2.12M (1.73%) | 373.65K Increased by +17.66% | Jun 30, 25 |
| 13 | Arrowstreet Capital Limited Partnership | 2.09M (1.71%) | 6.26K Increased by +0.30% | Dec 31, 25 |
| 14 | Fred Alger Management, LLC | 1.83M (1.50%) | 1.53M Increased by +83.26% | Dec 31, 25 |
| 15 | Deerfield Management Co | 1.83M (1.50%) | 839.95K Increased by +45.82% | Dec 31, 25 |
| 16 | The Goldman Sachs Group Inc | 1.77M (1.45%) | -341.44K Decreased by -19.25% | Sep 30, 25 |
| 17 | Driehaus Capital Management LLC | 1.77M (1.45%) | -330.06K Decreased by -18.65% | Dec 31, 25 |
| 18 | UBS Asset Mgmt Americas Inc | 1.76M (1.44%) | -924.83K Decreased by -52.56% | Sep 30, 25 |
| 19 | NORGES BANK | 1.70M (1.40%) | -220.49K Decreased by -12.94% | Dec 31, 25 |
| 20 | Morgan Stanley - Brokerage Accounts | 1.70M (1.40%) | -2.59K Decreased by -0.15% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 7.47M (6.12%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 2 | iShares Core S&P Mid-Cap ETF | 4.46M (3.66%) | 529.03K Increased by +11.85% | Feb 28, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 4.08M (3.34%) | 9.45K Increased by +0.23% | Jan 31, 26 |
| 4 | Vanguard US Total Market Shares ETF | 3.70M (3.03%) | 3.98K Increased by +0.11% | Sep 30, 24 |
| 5 | iShares Russell 2000 ETF | 3.23M (2.65%) | 1.01M Increased by +31.16% | Feb 28, 26 |
| 6 | Vanguard Small Cap Index | 2.92M (2.39%) | -314.00 Decreased by -0.01% | Jan 31, 26 |
| 7 | Fidelity Growth Compy Commingled Pl S | 2.74M (2.25%) | 36.67K Increased by +1.34% | Jan 31, 26 |
| 8 | Fidelity Growth Company Fund | 1.97M (1.62%) | 36.10K Increased by +1.83% | Jan 31, 26 |
| 9 | Invesco Global Multi Cap Growth | 1.80M (1.48%) | -196.30K Decreased by -10.88% | Dec 31, 23 |
| 10 | Invesco Global Opportunities A | 1.80M (1.48%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 11 | SPDR® S&P Biotech ETF | 1.73M (1.42%) | 3.86K Increased by +0.22% | Aug 31, 25 |
| 12 | Vanguard Small Cap Growth Index Inv | 1.62M (1.33%) | -25.89K Decreased by -1.59% | Jan 31, 26 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 1.49M (1.22%) | 2.60K Increased by +0.17% | Jan 31, 26 |
| 14 | State Street® SPDR® S&P® Biotech ETF | 1.41M (1.15%) | -49.57K Decreased by -3.52% | Feb 27, 26 |
| 15 | Fidelity Small Cap Index | 1.30M (1.07%) | 82.93K Increased by +6.38% | Dec 31, 25 |
| 16 | American Funds SMALLCAP World A | 1.28M (1.05%) | 454.63K Increased by +35.59% | Dec 31, 23 |
| 17 | Fidelity Growth Compy Commingled Pl O | 1.21M (0.99%) | 127.90K Increased by +10.55% | Aug 31, 24 |
| 18 | CS (Lux) Digital Health Equity SB USD | 1.20M (0.98%) | 50.00K Increased by +4.17% | Mar 31, 24 |
| 19 | UBS (Lux) Digital Health Equity SB USD | 1.20M (0.98%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 20 | SPDR® Portfolio S&P 600™ Sm Cap ETF | 1.12M (0.91%) | 13.33K Increased by +1.20% | Aug 29, 25 |