| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 18.16M (14.79%) | -3.16M Decreased by -17.38% | Mar 31, 26 |
| 2 | Vanguard Group Inc | 15.29M (12.46%) | -742.75K Decreased by -4.86% | Dec 31, 25 |
| 3 | venBio Select Advisor LLC | 10.70M (8.71%) | 75.00K Increased by +0.70% | Mar 31, 26 |
| 4 | FMR Inc | 7.27M (5.92%) | 746.24K Increased by +10.27% | Mar 31, 26 |
| 5 | Vanguard Portfolio Management, LLC | 7.15M (5.82%) | 7.15M Increased by +100.00% | Mar 31, 26 |
| 6 | State Street Corporation | 6.56M (5.34%) | -264.41K Decreased by -4.03% | Mar 31, 24 |
| 7 | State Street Corp | 6.50M (5.29%) | 92.30K Increased by +1.42% | Mar 31, 26 |
| 8 | Vanguard Capital Management, LLC | 6.03M (4.91%) | 6.03M Increased by +100.00% | Mar 31, 26 |
| 9 | Geode Capital Management, LLC | 4.28M (3.48%) | 1.01M Increased by +23.69% | Mar 31, 26 |
| 10 | Fred Alger Management, LLC | 3.34M (2.72%) | 1.51M Increased by +45.16% | Mar 31, 26 |
| 11 | Amvescap Plc. | 3.28M (2.67%) | 2.73M Increased by +83.30% | Mar 31, 26 |
| 12 | Artal Group S A | 3.19M (2.60%) | 152.72K Increased by +4.79% | Jun 30, 24 |
| 13 | Slate Path Capital LP | 2.52M (2.06%) | -2.46M Decreased by -97.42% | Dec 31, 25 |
| 14 | Vestal Point Capital LP | 2.27M (1.85%) | 1.38M Increased by +60.44% | Mar 31, 26 |
| 15 | Goldman Sachs Group Inc | 2.12M (1.72%) | 373.65K Increased by +17.66% | Jun 30, 25 |
| 16 | Arrowstreet Capital Limited Partnership | 2.09M (1.70%) | 6.26K Increased by +0.30% | Dec 31, 25 |
| 17 | Baker Bros Advisors LP | 1.99M (1.62%) | -182.86K Decreased by -9.18% | Mar 31, 26 |
| 18 | Driehaus Capital Management LLC | 1.77M (1.44%) | -330.06K Decreased by -18.65% | Dec 31, 25 |
| 19 | The Goldman Sachs Group Inc | 1.74M (1.42%) | 62.40K Increased by +3.59% | Mar 31, 26 |
| 20 | NORGES BANK | 1.70M (1.39%) | -220.49K Decreased by -12.94% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 7.47M (6.09%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 2 | iShares Core S&P Mid-Cap ETF | 4.75M (3.87%) | 894.00 Increased by +0.02% | May 29, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 4.24M (3.45%) | 10.58K Increased by +0.25% | Apr 30, 26 |
| 4 | Vanguard US Total Market Shares ETF | 3.70M (3.02%) | 3.98K Increased by +0.11% | Sep 30, 24 |
| 5 | iShares Russell 2000 ETF | 3.24M (2.64%) | 29.90K Increased by +0.92% | May 29, 26 |
| 6 | Vanguard Small Cap Index | 3.06M (2.50%) | -6.09K Decreased by -0.20% | Apr 30, 26 |
| 7 | Fidelity Growth Compy Commingled Pl S | 3.00M (2.44%) | 76.02K Increased by +2.54% | Apr 30, 26 |
| 8 | Fidelity Growth Company Fund | 2.27M (1.85%) | 58.10K Increased by +2.56% | Apr 30, 26 |
| 9 | Invesco Global Multi Cap Growth | 1.80M (1.47%) | -196.30K Decreased by -10.88% | Dec 31, 23 |
| 10 | Invesco Global Opportunities A | 1.80M (1.47%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 11 | SPDR® S&P Biotech ETF | 1.73M (1.41%) | 3.86K Increased by +0.22% | Aug 31, 25 |
| 12 | Vanguard Small Cap Growth Index Inv | 1.72M (1.40%) | 1.69K Increased by +0.10% | Apr 30, 26 |
| 13 | State Street® SPDR® S&P® Biotech ETF | 1.61M (1.31%) | -9.93K Decreased by -0.62% | May 31, 26 |
| 14 | Invesco S&P MidCap Momentum ETF | 1.59M (1.30%) | 2.15K Increased by +0.14% | May 29, 26 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 1.58M (1.29%) | 16.10K Increased by +1.02% | Apr 30, 26 |
| 16 | Fidelity Small Cap Index | 1.33M (1.08%) | 27.82K Increased by +2.10% | Mar 31, 26 |
| 17 | American Funds SMALLCAP World A | 1.28M (1.04%) | 454.63K Increased by +35.59% | Dec 31, 23 |
| 18 | Fidelity Growth Compy Commingled Pl O | 1.21M (0.99%) | 127.90K Increased by +10.55% | Aug 31, 24 |
| 19 | CS (Lux) Digital Health Equity SB USD | 1.20M (0.98%) | 50.00K Increased by +4.17% | Mar 31, 24 |
| 20 | UBS (Lux) Digital Health Equity SB USD | 1.20M (0.98%) | 0.00 Increased by 0.00% | Feb 28, 25 |