| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 7.88M (44.64%) | 6.65K Increased by +0.08% | Mar 31, 25 |
| 2 | Point72 Asset Management, L.P. | 2.37M (13.42%) | 2.37M Increased by +100.00% | Mar 31, 25 |
| 3 | BlackRock Inc | 2.18M (12.33%) | -371.87K Decreased by -17.08% | Mar 31, 25 |
| 4 | FMR Inc | 1.91M (10.79%) | -1.13M Decreased by -59.05% | Mar 31, 25 |
| 5 | Fairmount Funds Management LLC | 1.82M (10.29%) | 1.82M Increased by +100.00% | Dec 31, 24 |
| 6 | TANG CAPITAL MANAGEMENT LLC | 1.55M (8.75%) | 214.27K Increased by +13.87% | Mar 31, 25 |
| 7 | Vanguard Group Inc | 1.52M (8.59%) | -326.42K Decreased by -21.51% | Mar 31, 25 |
| 8 | Boxer Capital LLC | 1.30M (7.36%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | Boxer Capital Management, LLC | 1.30M (7.36%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | State Street Corporation | 1.21M (6.84%) | 763.06K Increased by +63.20% | Mar 31, 24 |
| 11 | Sofinnova Ventures | 1.16M (6.57%) | 1.03M Increased by +88.54% | Mar 31, 25 |
| 12 | Bank of America Corp | 1.14M (6.48%) | 1.13M Increased by +98.43% | Mar 31, 25 |
| 13 | Citigroup Inc | 1.07M (6.07%) | 1.02M Increased by +94.98% | Mar 31, 25 |
| 14 | BRAIDWELL LP | 1.05M (5.95%) | -104.60K Decreased by -9.96% | Sep 30, 23 |
| 15 | Palo Alto Investors, LLC | 1.02M (5.78%) | 176.74K Increased by +17.32% | Mar 31, 25 |
| 16 | Great Point Partners LLC | 976.98K (5.53%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 17 | T. Rowe Price Associates, Inc. | 915.08K (5.18%) | -9.93K Decreased by -1.08% | Mar 31, 25 |
| 18 | First Light Asset Management, LLC | 868.88K (4.92%) | -79.25K Decreased by -9.12% | Dec 31, 24 |
| 19 | State Street Corp | 860.72K (4.88%) | -425.03K Decreased by -49.38% | Mar 31, 25 |
| 20 | Sanofi | 821.92K (4.66%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 733.95K (4.16%) | 129.10K Increased by +17.59% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 668.95K (3.79%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 3 | Fidelity Small Cap Growth | 625.15K (3.54%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Eventide Healthcare & Life Sciences I | 568.32K (3.22%) | 141.32K Increased by +24.87% | Jun 30, 24 |
| 5 | T. Rowe Price New Horizons | 545.28K (3.09%) | -7.37K Decreased by -1.35% | Mar 31, 25 |
| 6 | US Small-Cap Growth II Equity Comp | 545.28K (3.09%) | -7.53K Decreased by -1.38% | Mar 31, 25 |
| 7 | iShares Russell 2000 ETF | 538.94K (3.05%) | 91.00 Increased by +0.02% | Apr 30, 25 |
| 8 | FIAM Small Cap Core Composite | 471.10K (2.67%) | -76.70K Decreased by -16.28% | Dec 31, 24 |
| 9 | FIAM Small Cap Core CIT Cl B | 460.10K (2.61%) | -11.00K Decreased by -2.39% | Feb 28, 25 |
| 10 | Fidelity Advisor Biotechnology I | 423.10K (2.40%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 11 | SPDR® S&P Biotech ETF | 372.70K (2.11%) | -5.47K Decreased by -1.47% | Apr 30, 25 |
| 12 | T. Rowe Price Health Sciences | 367.82K (2.08%) | 74.18K Increased by +20.17% | Sep 30, 24 |
| 13 | Fidelity Select Biotechnology | 341.57K (1.93%) | 66.10K Increased by +19.35% | Sep 30, 24 |
| 14 | Fidelity Stock Selector Small Cap | 317.17K (1.80%) | 15.50K Increased by +4.89% | Jan 31, 25 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 313.81K (1.78%) | 520.00 Increased by +0.17% | Apr 30, 25 |
| 16 | Fidelity Small Cap Growth K6 | 278.89K (1.58%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 17 | Fidelity Series Small Cap Opps | 269.44K (1.53%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 18 | Vanguard Small Cap Index | 268.97K (1.52%) | 231.00 Increased by +0.09% | Feb 28, 25 |
| 19 | Bridge Builder Small/Mid Cap Growth | 247.13K (1.40%) | 55.98K Increased by +22.65% | Apr 30, 25 |
| 20 | Franklin Biotechnology Discv A(acc)USD | 225.38K (1.28%) | 0.00 Increased by 0.00% | Apr 30, 25 |