| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 7.87M (46.99%) | 78.45K Increased by +1.00% | Dec 31, 24 |
| 2 | FMR Inc | 3.03M (18.08%) | -278.94K Decreased by -9.21% | Dec 31, 24 |
| 3 | BlackRock Inc | 2.55M (15.21%) | 368.28K Increased by +14.45% | Dec 31, 24 |
| 4 | Vanguard Group Inc | 1.84M (11.00%) | 143.58K Increased by +7.79% | Dec 31, 24 |
| 5 | Fairmount Funds Management LLC | 1.82M (10.84%) | 1.82M Increased by +100.00% | Dec 31, 24 |
| 6 | TANG CAPITAL MANAGEMENT LLC | 1.33M (7.94%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | Boxer Capital LLC | 1.30M (7.76%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 8 | Boxer Capital Management, LLC | 1.30M (7.76%) | 1.30M Increased by +100.00% | Dec 31, 24 |
| 9 | State Street Corp | 1.29M (7.67%) | 379.57K Increased by +29.52% | Dec 31, 24 |
| 10 | Camber Capital Management LLC | 1.25M (7.46%) | 1.25M Increased by +100.00% | Dec 31, 24 |
| 11 | State Street Corporation | 1.21M (7.21%) | 763.06K Increased by +63.20% | Mar 31, 24 |
| 12 | BRAIDWELL LP | 1.05M (6.26%) | -104.60K Decreased by -9.96% | Sep 30, 23 |
| 13 | Great Point Partners LLC | 976.98K (5.83%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 14 | T. Rowe Price Associates, Inc. | 925.01K (5.52%) | 1.89K Increased by +0.20% | Dec 31, 24 |
| 15 | First Light Asset Management, LLC | 868.88K (5.19%) | -79.25K Decreased by -9.12% | Dec 31, 24 |
| 16 | Point72 Asset Management, L.P. | 864.10K (5.16%) | 72.90K Increased by +8.44% | Mar 31, 24 |
| 17 | Palo Alto Investors, LLC | 843.97K (5.04%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Sanofi | 821.92K (4.90%) | 821.92K Increased by +100.00% | Dec 31, 24 |
| 19 | Mangrove Partners | 689.52K (4.11%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | Morgan Stanley - Brokerage Accounts | 636.11K (3.80%) | 34.08K Increased by +5.36% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 733.95K (4.38%) | 129.10K Increased by +17.59% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 668.95K (3.99%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Fidelity Small Cap Growth | 625.15K (3.73%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Eventide Healthcare & Life Sciences I | 568.32K (3.39%) | 141.32K Increased by +24.87% | Jun 30, 24 |
| 5 | T. Rowe Price New Horizons | 545.28K (3.25%) | -7.37K Decreased by -1.35% | Mar 31, 25 |
| 6 | US Small-Cap Growth II Equity Comp | 545.28K (3.25%) | -7.53K Decreased by -1.38% | Mar 31, 25 |
| 7 | iShares Russell 2000 ETF | 538.85K (3.22%) | -4.37K Decreased by -0.81% | Apr 29, 25 |
| 8 | FIAM Small Cap Core Composite | 471.10K (2.81%) | -76.70K Decreased by -16.28% | Dec 31, 24 |
| 9 | FIAM Small Cap Core CIT Cl B | 460.10K (2.75%) | -11.00K Decreased by -2.39% | Feb 28, 25 |
| 10 | Fidelity Advisor Biotechnology I | 423.10K (2.52%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 11 | SPDR® S&P Biotech ETF | 371.64K (2.22%) | -6.54K Decreased by -1.76% | Apr 30, 25 |
| 12 | T. Rowe Price Health Sciences | 367.82K (2.20%) | 74.18K Increased by +20.17% | Sep 30, 24 |
| 13 | Fidelity Select Biotechnology | 341.57K (2.04%) | 66.10K Increased by +19.35% | Sep 30, 24 |
| 14 | Fidelity Stock Selector Small Cap | 317.17K (1.89%) | 15.50K Increased by +4.89% | Jan 31, 25 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 313.29K (1.87%) | 2.44K Increased by +0.78% | Mar 31, 25 |
| 16 | Fidelity Small Cap Growth K6 | 278.89K (1.66%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 17 | Fidelity Series Small Cap Opps | 269.44K (1.61%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 18 | Vanguard Small Cap Index | 268.97K (1.61%) | 231.00 Increased by +0.09% | Feb 28, 25 |
| 19 | Franklin Biotechnology Discv A(acc)USD | 225.38K (1.34%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | Fidelity Small Cap Index | 214.88K (1.28%) | 4.46K Increased by +2.08% | Feb 28, 25 |