| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 7.88M (44.76%) | 6.65K Increased by +0.08% | Mar 31, 25 |
| 2 | First Light Asset Management, LLC | 4.63M (26.32%) | 3.76M Increased by +81.25% | Mar 31, 25 |
| 3 | Point72 Asset Management, L.P. | 2.37M (13.45%) | 2.37M Increased by +100.00% | Mar 31, 25 |
| 4 | BlackRock Inc | 2.18M (12.36%) | -371.87K Decreased by -17.08% | Mar 31, 25 |
| 5 | FMR Inc | 1.91M (10.82%) | -1.13M Decreased by -59.05% | Mar 31, 25 |
| 6 | Fairmount Funds Management LLC | 1.82M (10.32%) | 1.82M Increased by +100.00% | Dec 31, 24 |
| 7 | TANG CAPITAL MANAGEMENT LLC | 1.55M (8.78%) | 214.27K Increased by +13.87% | Mar 31, 25 |
| 8 | Vanguard Group Inc | 1.52M (8.62%) | -326.42K Decreased by -21.51% | Mar 31, 25 |
| 9 | Boxer Capital LLC | 1.30M (7.38%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Boxer Capital Management, LLC | 1.30M (7.38%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | State Street Corporation | 1.21M (6.86%) | 763.06K Increased by +63.20% | Mar 31, 24 |
| 12 | Sofinnova Ventures | 1.16M (6.59%) | 1.03M Increased by +88.54% | Mar 31, 25 |
| 13 | Bank of America Corp | 1.14M (6.50%) | 1.13M Increased by +98.43% | Mar 31, 25 |
| 14 | Citigroup Inc | 1.07M (6.08%) | 1.02M Increased by +94.98% | Mar 31, 25 |
| 15 | BRAIDWELL LP | 1.05M (5.96%) | -104.60K Decreased by -9.96% | Sep 30, 23 |
| 16 | Palo Alto Investors, LLC | 1.02M (5.80%) | 176.74K Increased by +17.32% | Mar 31, 25 |
| 17 | Great Point Partners LLC | 976.98K (5.55%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 18 | T. Rowe Price Associates, Inc. | 915.08K (5.20%) | -9.93K Decreased by -1.08% | Mar 31, 25 |
| 19 | State Street Corp | 860.72K (4.89%) | -425.03K Decreased by -49.38% | Mar 31, 25 |
| 20 | Sanofi | 821.92K (4.67%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 733.95K (4.17%) | 129.10K Increased by +17.59% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 683.75K (3.88%) | 14.80K Increased by +2.16% | May 31, 25 |
| 3 | Fidelity Small Cap Growth | 625.15K (3.55%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Eventide Healthcare & Life Sciences I | 568.32K (3.23%) | 141.32K Increased by +24.87% | Jun 30, 24 |
| 5 | iShares Russell 2000 ETF | 545.85K (3.10%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | T. Rowe Price New Horizons | 545.28K (3.10%) | -7.37K Decreased by -1.35% | Mar 31, 25 |
| 7 | US Small-Cap Growth II Equity Comp | 545.28K (3.10%) | -7.53K Decreased by -1.38% | Mar 31, 25 |
| 8 | FIAM Small Cap Core Composite | 471.10K (2.68%) | -76.70K Decreased by -16.28% | Dec 31, 24 |
| 9 | FIAM Small Cap Core CIT Cl B | 460.10K (2.61%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Fidelity Advisor Biotechnology I | 423.10K (2.40%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 11 | T. Rowe Price Health Sciences | 367.82K (2.09%) | 74.18K Increased by +20.17% | Sep 30, 24 |
| 12 | SPDR® S&P Biotech ETF | 358.72K (2.04%) | 2.13K Increased by +0.59% | May 31, 25 |
| 13 | Fidelity Select Biotechnology | 341.57K (1.94%) | 66.10K Increased by +19.35% | Sep 30, 24 |
| 14 | Fidelity Stock Selector Small Cap | 317.17K (1.80%) | 15.50K Increased by +4.89% | Jan 31, 25 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 316.38K (1.80%) | 2.56K Increased by +0.81% | May 31, 25 |
| 16 | Fidelity Small Cap Growth K6 | 280.31K (1.59%) | 1.42K Increased by +0.51% | Mar 31, 25 |
| 17 | Nuveen Quant Small Cap Equity R6 | 276.42K (1.57%) | 276.42K Increased by +100.00% | Apr 30, 25 |
| 18 | Fidelity Series Small Cap Opps | 269.44K (1.53%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 19 | Vanguard Small Cap Index | 268.97K (1.53%) | 231.00 Increased by +0.09% | Feb 28, 25 |
| 20 | Bridge Builder Small/Mid Cap Growth | 253.30K (1.44%) | 6.17K Increased by +2.44% | May 31, 25 |