| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Perceptive Advisors LLC | 6.77M (11.62%) | 4.65M Increased by +68.62% | Dec 31, 24 |
| 2 | TCG Crossover Management, LLC | 4.64M (7.97%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Viking Global Investors LP | 2.96M (5.08%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 4 | Vanguard Group Inc | 2.69M (4.62%) | -397.16K Decreased by -14.75% | Dec 31, 24 |
| 5 | Stonepine Capital Management Llc | 2.50M (4.29%) | -15.87K Decreased by -0.63% | Dec 31, 23 |
| 6 | Bank of America Corp | 2.43M (4.16%) | 1.51M Increased by +62.39% | Dec 31, 24 |
| 7 | BlackRock Inc | 2.28M (3.91%) | -269.27K Decreased by -11.82% | Dec 31, 24 |
| 8 | State Street Corporation | 2.06M (3.53%) | 618.64K Increased by +30.03% | Mar 31, 24 |
| 9 | Almitas Capital LLC | 2.03M (3.49%) | 43.81K Increased by +2.16% | Dec 31, 24 |
| 10 | abrdn PLC | 1.97M (3.38%) | 1.85M Increased by +94.00% | Sep 30, 24 |
| 11 | Citadel Advisors Llc | 1.97M (3.38%) | 71.14K Increased by +3.61% | Dec 31, 24 |
| 12 | 683 Capital Management LLC | 1.93M (3.31%) | -70.00K Decreased by -3.63% | Dec 31, 24 |
| 13 | Goldman Sachs Group Inc | 1.86M (3.19%) | 246.03K Increased by +13.23% | Dec 31, 24 |
| 14 | Franklin Resources Inc | 1.86M (3.18%) | 530.88K Increased by +28.61% | Mar 31, 24 |
| 15 | Morgan Stanley - Brokerage Accounts | 1.85M (3.17%) | -2.29M Decreased by -123.99% | Jun 30, 24 |
| 16 | Avidity Partners Management LP | 1.76M (3.01%) | 855.54K Increased by +48.69% | Sep 30, 23 |
| 17 | Boxer Capital Management, LLC | 1.75M (3.00%) | 1.75M Increased by +100.00% | Dec 31, 24 |
| 18 | Aberdeen Group PLC | 1.72M (2.96%) | -249.44K Decreased by -14.48% | Dec 31, 24 |
| 19 | Adage Capital Partners Gp LLC | 1.70M (2.92%) | 932.00K Increased by +54.82% | Sep 30, 23 |
| 20 | Millennium Management LLC | 1.54M (2.63%) | -936.28K Decreased by -60.99% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.30M (3.94%) | 135.79K Increased by +5.91% | Mar 31, 25 |
| 2 | abrdn Healthcare Investors | 1.69M (2.89%) | 48.97K Increased by +2.90% | Mar 31, 25 |
| 3 | Franklin Biotechnology Discv A(acc)USD | 1.22M (2.10%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 4 | iShares Russell 2000 ETF | 1.16M (1.99%) | -12.93K Decreased by -1.12% | May 29, 24 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 1.13M (1.94%) | 399.85K Increased by +35.32% | Mar 31, 25 |
| 6 | Eventide Healthcare & Life Sciences I | 1.12M (1.92%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 7 | SPDR® S&P Pharmaceuticals ETF | 981.23K (1.68%) | 0.00 Increased by 0.00% | May 30, 24 |
| 8 | abrdn Life Sciences Investors | 743.09K (1.27%) | 21.05K Increased by +2.83% | Mar 31, 25 |
| 9 | Fidelity Select Biotechnology | 670.51K (1.15%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 10 | Vanguard Small Cap Index | 646.02K (1.11%) | 1.52K Increased by +0.24% | Aug 31, 24 |
| 11 | Franklin Biotechnology Discovery A | 633.59K (1.09%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 12 | Fidelity® Select Biotechnology | 529.80K (0.91%) | 326.70K Increased by +61.66% | Nov 30, 23 |
| 13 | CREF Stock R1 | 515.29K (0.88%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 14 | Fidelity Small Cap Index | 508.11K (0.87%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 15 | Fidelity® Small Cap Index | 495.04K (0.85%) | 14.60K Increased by +2.95% | Oct 31, 23 |
| 16 | Jupiter Merian Glb Eq AbsRet I USD Acc | 480.21K (0.82%) | 185.87K Increased by +38.70% | Dec 31, 23 |
| 17 | iShares Russell 2000 Growth ETF | 431.45K (0.74%) | 0.00 Increased by 0.00% | May 29, 24 |
| 18 | iShares Biotechnology ETF | 397.64K (0.68%) | -4.43K Decreased by -1.11% | Mar 31, 25 |
| 19 | Fidelity Series Small Cap Opps | 380.40K (0.65%) | 14.00K Increased by +3.68% | Nov 30, 23 |
| 20 | Fidelity® Series Small Cap Opps | 366.40K (0.63%) | 366.40K Increased by +100.00% | Oct 31, 23 |