| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Perceptive Advisors LLC | 7.90M (13.48%) | 28.02K Increased by +0.35% | Jun 30, 25 |
| 2 | TCG Crossover Management, LLC | 5.94M (10.14%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Adage Capital Partners Gp LLC | 5.70M (9.72%) | 5.70M Increased by +100.00% | Mar 31, 25 |
| 4 | Point72 Asset Management, L.P. | 4.54M (7.74%) | 3.62M Increased by +79.79% | Jun 30, 25 |
| 5 | Vanguard Group Inc | 4.50M (7.67%) | 381.52K Increased by +8.48% | Jun 30, 25 |
| 6 | Millennium Management LLC | 3.08M (5.26%) | 2.49M Increased by +80.72% | Mar 31, 25 |
| 7 | FMR Inc | 3.05M (5.20%) | 1.89M Increased by +62.01% | Jun 30, 25 |
| 8 | Viking Global Investors LP | 2.96M (5.05%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 9 | Nantahala Capital Management, LLC | 2.93M (5.01%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Stonepine Capital Management Llc | 2.50M (4.27%) | -15.87K Decreased by -0.63% | Dec 31, 23 |
| 11 | Aberdeen Group PLC | 2.43M (4.15%) | 707.55K Increased by +29.11% | Mar 31, 25 |
| 12 | Saturn V Capital Management LLC | 2.43M (4.14%) | 1.54M Increased by +63.36% | Mar 31, 25 |
| 13 | Bank of America Corp | 2.43M (4.14%) | 1.51M Increased by +62.39% | Dec 31, 24 |
| 14 | BlackRock Inc | 2.39M (4.07%) | 108.47K Increased by +4.54% | Mar 31, 25 |
| 15 | 683 Capital Management LLC | 2.16M (3.69%) | -251.40K Decreased by -11.64% | Jun 30, 25 |
| 16 | Almitas Capital LLC | 2.12M (3.62%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 17 | State Street Corporation | 2.06M (3.51%) | 618.64K Increased by +30.03% | Mar 31, 24 |
| 18 | Great Point Partners LLC | 2.00M (3.41%) | 188.00K Increased by +9.40% | Jun 30, 25 |
| 19 | abrdn PLC | 1.97M (3.36%) | 1.85M Increased by +94.00% | Sep 30, 24 |
| 20 | Franklin Resources Inc | 1.86M (3.17%) | 530.88K Increased by +28.61% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.25M (3.83%) | -49.88K Decreased by -2.22% | Jul 31, 25 |
| 2 | iShares Russell 2000 ETF | 1.67M (2.85%) | -18.65K Decreased by -1.11% | Aug 29, 25 |
| 3 | Fidelity Select Biotechnology | 1.34M (2.28%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 4 | Franklin Biotechnology Discv A(acc)USD | 1.22M (2.09%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 5 | Eventide Healthcare & Life Sciences I | 1.12M (1.91%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 6 | Fidelity Small Cap Growth | 987.13K (1.68%) | 987.13K Increased by +100.00% | Jun 30, 25 |
| 7 | SPDR® S&P Pharmaceuticals ETF | 981.23K (1.67%) | 0.00 Increased by 0.00% | May 30, 24 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 779.02K (1.33%) | -356.52K Decreased by -45.77% | Jul 31, 25 |
| 9 | Fidelity Small Cap Index | 695.51K (1.19%) | 695.51K Increased by +100.00% | Jun 30, 25 |
| 10 | Vanguard Small Cap Index | 646.02K (1.10%) | 1.52K Increased by +0.24% | Aug 31, 24 |
| 11 | Franklin Biotechnology Discovery A | 633.59K (1.08%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 12 | Fidelity® Select Biotechnology | 529.80K (0.90%) | 326.70K Increased by +61.66% | Nov 30, 23 |
| 13 | CREF Stock R1 | 515.29K (0.88%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 14 | Fidelity® Small Cap Index | 495.04K (0.84%) | 14.60K Increased by +2.95% | Oct 31, 23 |
| 15 | Fidelity Small Cap Growth K6 | 492.63K (0.84%) | 492.63K Increased by +100.00% | Jun 30, 25 |
| 16 | Jupiter Merian Glb Eq AbsRet I USD Acc | 480.21K (0.82%) | 185.87K Increased by +38.70% | Dec 31, 23 |
| 17 | iShares Russell 2000 Growth ETF | 471.66K (0.80%) | 0.00 Increased by 0.00% | Aug 29, 25 |
| 18 | Invesco Dorsey Wright SmallCap Momt ETF | 446.98K (0.76%) | 580.00 Increased by +0.13% | Aug 29, 25 |
| 19 | abrdn Healthcare Investors | 403.36K (0.69%) | -115.08K Decreased by -28.53% | Jul 31, 25 |
| 20 | iShares Biotechnology ETF | 392.05K (0.67%) | -3.45K Decreased by -0.88% | Aug 29, 25 |