| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 16.52M (19.93%) | 5.14M Increased by +31.11% | Dec 31, 25 |
| 2 | Perceptive Advisors LLC | 8.95M (10.80%) | 1.05M Increased by +11.73% | Sep 30, 25 |
| 3 | BlackRock Inc | 7.14M (8.62%) | 1.63M Increased by +22.83% | Sep 30, 25 |
| 4 | TCG Crossover Management, LLC | 6.24M (7.53%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 5 | Vanguard Group Inc | 5.80M (7.00%) | 531.16K Increased by +9.15% | Dec 31, 25 |
| 6 | COMMODORE CAPITAL LP | 5.65M (6.82%) | 1.57M Increased by +27.87% | Dec 31, 25 |
| 7 | Saturn V Capital Management LLC | 4.50M (5.43%) | -108.39K Decreased by -2.41% | Dec 31, 25 |
| 8 | First Light Asset Management, LLC | 3.36M (4.05%) | -343.00 Decreased by -0.01% | Dec 31, 25 |
| 9 | Driehaus Capital Management LLC | 3.11M (3.75%) | 688.74K Increased by +22.15% | Dec 31, 25 |
| 10 | Viking Global Investors LP | 2.96M (3.57%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 11 | Nantahala Capital Management, LLC | 2.93M (3.54%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Point72 Asset Management, L.P. | 2.79M (3.37%) | -1.75M Decreased by -62.59% | Sep 30, 25 |
| 13 | Adage Capital Partners Gp LLC | 2.78M (3.35%) | -4.04M Decreased by -145.47% | Dec 31, 25 |
| 14 | HHG PLC | 2.54M (3.06%) | 2.54M Increased by +100.00% | Sep 30, 25 |
| 15 | Stonepine Capital Management Llc | 2.50M (3.02%) | -15.87K Decreased by -0.63% | Dec 31, 23 |
| 16 | Aberdeen Group PLC | 2.43M (2.93%) | 707.55K Increased by +29.11% | Mar 31, 25 |
| 17 | Bank of America Corp | 2.43M (2.93%) | 1.51M Increased by +62.39% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 2.17M (2.61%) | 353.50K Increased by +16.32% | Dec 31, 25 |
| 19 | Almitas Capital LLC | 2.12M (2.56%) | -2.12M Decreased by -100.00% | Dec 31, 25 |
| 20 | State Street Corporation | 2.06M (2.49%) | 618.64K Increased by +30.03% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.10M (3.74%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 2 | Fidelity Advisor Biotechnology I | 2.43M (2.94%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 3 | iShares Russell 2000 ETF | 2.15M (2.59%) | 1.89M Increased by +87.98% | Feb 28, 26 |
| 4 | Fidelity Small Cap Growth | 2.12M (2.55%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 5 | Eventide Healthcare & Life Sciences I | 1.51M (1.82%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | Fidelity Select Health Care | 1.42M (1.71%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 7 | Fidelity Select Biotechnology | 1.33M (1.61%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 8 | Xtrackers S&P 500 Swap ETF 1C | 1.24M (1.50%) | -9.15K Decreased by -0.74% | Dec 31, 25 |
| 9 | Fidelity Stock Selector Small Cap | 1.09M (1.31%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Strategic Advisers Fidelity US TtlStk | 1.08M (1.30%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 11 | Fidelity Small Cap Growth K6 | 1.05M (1.27%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 12 | SPDR® S&P Pharmaceuticals ETF | 981.23K (1.18%) | 0.00 Increased by 0.00% | May 30, 24 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 906.18K (1.09%) | 10.32K Increased by +1.14% | Feb 28, 26 |
| 14 | Fidelity Series Small Cap Opps | 881.40K (1.06%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 15 | Fidelity Balanced | 879.84K (1.06%) | -398.00 Decreased by -0.05% | Dec 31, 25 |
| 16 | Fidelity Small Cap Index | 872.01K (1.05%) | 173.16K Increased by +19.86% | Dec 31, 25 |
| 17 | Janus Henderson Hrzn Biotec E2 USD | 806.92K (0.97%) | 806.92K Increased by +100.00% | Dec 31, 25 |
| 18 | Franklin Biotechnology Discv A(acc)USD | 760.08K (0.92%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 19 | Fidelity Advisor Health Care I | 715.00K (0.86%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 20 | iShares Biotechnology ETF | 678.48K (0.82%) | 0.00 Increased by 0.00% | Feb 28, 26 |