| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | venBio Partners LLC | 9.70M (9.32%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Vivo Capital, LLC | 4.03M (3.88%) | -185.53K Decreased by -4.60% | Sep 30, 24 |
| 3 | Vestal Point Capital LP | 3.60M (3.46%) | 990.00K Increased by +27.50% | Jun 30, 24 |
| 4 | Redmile Group, LLC | 3.33M (3.20%) | -58.47K Decreased by -1.75% | Sep 30, 25 |
| 5 | Millennium Management LLC | 3.20M (3.08%) | 581.76K Increased by +18.15% | Dec 31, 25 |
| 6 | TANG CAPITAL MANAGEMENT LLC | 3.16M (3.03%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Cormorant Asset Management, LLC | 3.14M (3.02%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 8 | Almitas Capital LLC | 2.54M (2.44%) | -2.54M Decreased by -100.00% | Dec 31, 25 |
| 9 | Orbimed Advisors, LLC | 1.89M (1.82%) | -823.51K Decreased by -43.47% | Jun 30, 24 |
| 10 | FMR Inc | 1.85M (1.78%) | -4.01M Decreased by -216.77% | Dec 31, 24 |
| 11 | Vanguard Group Inc | 1.63M (1.57%) | 102.32K Increased by +6.27% | Dec 31, 25 |
| 12 | Paradigm Biocapital Advisors LP | 1.58M (1.51%) | 1.58M Increased by +100.00% | Jun 30, 24 |
| 13 | Driehaus Capital Management LLC | 1.42M (1.37%) | 627.11K Increased by +44.07% | Dec 31, 25 |
| 14 | BRAIDWELL LP | 1.25M (1.20%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | Acadian Asset Management LLC | 1.22M (1.17%) | 1.22M Increased by +100.00% | Sep 30, 25 |
| 16 | Logos Global Management LP | 1.00M (0.96%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 17 | State Street Corp | 718.85K (0.69%) | 34.73K Increased by +4.83% | Mar 31, 25 |
| 18 | Two Sigma Advisers, LLC | 710.40K (0.68%) | -9.40K Decreased by -1.32% | Dec 31, 25 |
| 19 | Ameriprise Financial Inc | 652.90K (0.63%) | 652.90K Increased by +100.00% | Sep 30, 25 |
| 20 | Two Sigma Investments LLC | 640.21K (0.62%) | 33.53K Increased by +5.24% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HBM Healthcare Investments AG Ord | 4.77M (4.58%) | 269.04K Increased by +5.64% | Dec 31, 25 |
| 2 | Fidelity Small Cap Growth | 1.69M (1.62%) | -78.26K Decreased by -4.63% | Aug 31, 24 |
| 3 | Fidelity® Small Cap Growth | 1.35M (1.29%) | 564.89K Increased by +41.98% | Oct 31, 23 |
| 4 | Fidelity® Select Biotechnology | 1.14M (1.09%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 5 | Vanguard US Total Market Shares ETF | 984.59K (0.95%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Fidelity® Small Cap Value | 970.00K (0.93%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 7 | Vanguard Total Stock Mkt Idx Inv | 960.45K (0.92%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 8 | Fidelity Advisor Biotechnology I | 924.23K (0.89%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | Fidelity Advisor® Biotechnology I | 922.70K (0.89%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 10 | Fidelity Advisor® Growth Opps M | 900.50K (0.87%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 11 | Fidelity Advisor Growth Opps M | 899.00K (0.86%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 12 | Fidelity® Series Small Cap Opps | 856.84K (0.82%) | 519.24K Increased by +60.60% | Oct 31, 23 |
| 13 | Fidelity Stock Selector Small Cap | 837.11K (0.80%) | 10.71K Increased by +1.28% | Dec 31, 24 |
| 14 | Fidelity Select Biotechnology | 835.50K (0.80%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Fidelity Series Small Cap Opps | 769.53K (0.74%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 16 | Fidelity Small Cap Value Fund | 678.40K (0.65%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 17 | Fidelity Small Cap Growth K6 | 621.50K (0.60%) | -25.03K Decreased by -4.03% | Aug 31, 24 |
| 18 | Biotech Growth Ord | 512.26K (0.49%) | 105.00K Increased by +20.50% | Jun 30, 24 |
| 19 | Fidelity® Small Cap Growth K6 | 475.80K (0.46%) | 242.87K Increased by +51.05% | Oct 31, 23 |
| 20 | Fidelity® Stock Selector Small Cap | 416.50K (0.40%) | 266.70K Increased by +64.03% | Oct 31, 23 |